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DE3887194D1 - Antitumor-Platinkomplexe, deren Herstellung und deren therapeutische Verwendung. - Google Patents

Antitumor-Platinkomplexe, deren Herstellung und deren therapeutische Verwendung.

Info

Publication number
DE3887194D1
DE3887194D1 DE88304140T DE3887194T DE3887194D1 DE 3887194 D1 DE3887194 D1 DE 3887194D1 DE 88304140 T DE88304140 T DE 88304140T DE 3887194 T DE3887194 T DE 3887194T DE 3887194 D1 DE3887194 D1 DE 3887194D1
Authority
DE
Germany
Prior art keywords
production
therapeutic use
platinum complexes
antitumor platinum
antitumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88304140T
Other languages
English (en)
Other versions
DE3887194T2 (de
Inventor
Yokio Sugimura
Yukiko Kameyama
Toshihiko Hashimoto
Kimio Iino
Tomoyuki Shibata
Shigeki Muramatsu
Tomowo Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of DE3887194D1 publication Critical patent/DE3887194D1/de
Application granted granted Critical
Publication of DE3887194T2 publication Critical patent/DE3887194T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE3887194T 1987-05-08 1988-05-06 Antitumor-Platinkomplexe, deren Herstellung und deren therapeutische Verwendung. Expired - Fee Related DE3887194T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11218187 1987-05-08
JP11450087 1987-05-13

Publications (2)

Publication Number Publication Date
DE3887194D1 true DE3887194D1 (de) 1994-03-03
DE3887194T2 DE3887194T2 (de) 1994-07-28

Family

ID=26451415

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3887194T Expired - Fee Related DE3887194T2 (de) 1987-05-08 1988-05-06 Antitumor-Platinkomplexe, deren Herstellung und deren therapeutische Verwendung.

Country Status (13)

Country Link
US (2) US5527905A (de)
EP (1) EP0290280B1 (de)
KR (1) KR950008372B1 (de)
CN (1) CN1017803B (de)
AU (1) AU617314B2 (de)
CA (1) CA1308723C (de)
DE (1) DE3887194T2 (de)
DK (1) DK252688A (de)
ES (1) ES2061646T3 (de)
FI (1) FI87572C (de)
HU (1) HU199492B (de)
NO (1) NO178069C (de)
RU (1) RU2039064C1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0164460B1 (ko) * 1995-10-02 1999-03-20 김은영 고분자 백금 착화합물, 그의 제조방법 및 그를 유효성분으로 하는 항암제
US6235782B1 (en) 1998-11-12 2001-05-22 Rifat Pamukcu Method for treating a patient with neoplasia by treatment with a platinum coordination complex
US6235776B1 (en) 1998-11-12 2001-05-22 Cell Pathways, Inc. Method for treating a patient with neoplasia by treatment with a paclitaxel derivative
EP1229934B1 (de) 1999-10-01 2014-03-05 Immunogen, Inc. Zusammensetzungen und verfahren zur behandlung von krebs mittels immunkonjugaten und chemotherapeutischen agenzien
EP1235598A2 (de) * 1999-11-12 2002-09-04 Angiotech Pharmaceuticals, Inc. Zusammensetzung von ein kombination von radioaktive therapie und zellzyklus inhibitoren
KR100363394B1 (ko) 2000-08-21 2002-12-05 한국과학기술연구원 온도감응성을 갖는 포스파젠삼량체-백금착물 복합체, 그의제조방법 및 그를 함유하는 항암제 조성물
AU2003300076C1 (en) 2002-12-30 2010-03-04 Angiotech International Ag Drug delivery from rapid gelling polymer composition
US7138520B2 (en) * 2003-01-13 2006-11-21 Massachusetts Institute Of Technology Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
PT1695991E (pt) * 2003-12-10 2010-03-02 Toudai Tlo Ltd Complexo de coordenação de diaminociclohexano platina (ii) com copolímero de bloco contendo segmento poli(ácido carboxílico) e agente antitumoral compreendendo o mesmo
CA2807823C (en) 2010-08-24 2023-02-07 The Brigham And Women's Hospital, Inc. Methods for predicting anti-cancer response
ES2768344T3 (es) 2011-06-17 2020-06-22 Myriad Genetics Inc Métodos y materiales para evaluar el desequilibrio alélico
WO2013096843A1 (en) 2011-12-21 2013-06-27 Myriad Genetics, Inc. Methods and materials for assessing loss of heterozygosity
AU2013226400B2 (en) 2012-02-23 2018-09-06 Dana-Farber Cancer Institute, Inc. Methods for predicting anti-cancer response
CA3190075A1 (en) 2012-06-07 2013-12-12 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
WO2014160080A1 (en) 2013-03-14 2014-10-02 Children's Medical Center Corporation Cancer diagnosis, treatment selection and treatment
WO2015086473A1 (en) 2013-12-09 2015-06-18 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
EP4234711B1 (de) 2014-08-15 2025-05-28 Myriad Genetics, Inc. Verfahren und materialien zur beurteilung eines mangels an homologer rekombination
CN111721842B (zh) * 2019-03-19 2022-07-12 海南长安国际制药有限公司 洛铂中有关物质的检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体
GB2019397B (en) * 1978-04-20 1982-10-27 Johnson Matthey Co Ltd Pt 2 and 4 complexes with amino-acids
IL67789A (en) * 1983-01-31 1986-09-30 Yissum Res Dev Co Amino-substituted malonato platinum(ii)complexes and method for their preparation
PH25038A (en) * 1985-09-06 1991-01-28 Sankyo Co Anti-tumor platinum complexes
DE3630497A1 (de) * 1986-09-08 1988-03-10 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel

Also Published As

Publication number Publication date
KR950008372B1 (ko) 1995-07-28
CN1034544A (zh) 1989-08-09
KR880013961A (ko) 1988-12-22
FI87572C (fi) 1993-01-25
NO882012D0 (no) 1988-05-09
NO178069C (no) 1996-01-17
FI882130A0 (fi) 1988-05-06
AU1581388A (en) 1988-11-10
EP0290280A3 (en) 1990-07-25
ES2061646T3 (es) 1994-12-16
RU2039064C1 (ru) 1995-07-09
DK252688A (da) 1988-11-09
DE3887194T2 (de) 1994-07-28
EP0290280A2 (de) 1988-11-09
DK252688D0 (da) 1988-05-06
HUT47301A (en) 1989-02-28
NO882012L (no) 1989-02-27
CA1308723C (en) 1992-10-13
US5633243A (en) 1997-05-27
US5527905A (en) 1996-06-18
NO178069B (no) 1995-10-09
FI882130A7 (fi) 1988-11-09
EP0290280B1 (de) 1994-01-19
CN1017803B (zh) 1992-08-12
AU617314B2 (en) 1991-11-28
HU199492B (en) 1990-02-28
FI87572B (fi) 1992-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee