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DE3878167D1 - Auf ultrakleine kolloidale metallteilchen gegruendetes, allgemein anwendbares nachweissystem. - Google Patents

Auf ultrakleine kolloidale metallteilchen gegruendetes, allgemein anwendbares nachweissystem.

Info

Publication number
DE3878167D1
DE3878167D1 DE8888202521T DE3878167T DE3878167D1 DE 3878167 D1 DE3878167 D1 DE 3878167D1 DE 8888202521 T DE8888202521 T DE 8888202521T DE 3878167 T DE3878167 T DE 3878167T DE 3878167 D1 DE3878167 D1 DE 3878167D1
Authority
DE
Germany
Prior art keywords
ultra
system based
metal particles
detecting system
colloidal metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888202521T
Other languages
English (en)
Other versions
DE3878167T2 (de
Inventor
Johannes L M Leunissen
Brabander Marc J De
De Plas Petrus F E M Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of DE3878167D1 publication Critical patent/DE3878167D1/de
Publication of DE3878167T2 publication Critical patent/DE3878167T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/801—Electron dense compounds, e.g. ferritin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/811—Peptides or proteins is immobilized on, or in, an inorganic carrier

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE8888202521T 1987-11-16 1988-11-11 Auf ultrakleine kolloidale metallteilchen gegruendetes, allgemein anwendbares nachweissystem. Expired - Lifetime DE3878167T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87202231 1987-11-16

Publications (2)

Publication Number Publication Date
DE3878167D1 true DE3878167D1 (de) 1993-03-18
DE3878167T2 DE3878167T2 (de) 1993-05-27

Family

ID=8197700

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888202521T Expired - Lifetime DE3878167T2 (de) 1987-11-16 1988-11-11 Auf ultrakleine kolloidale metallteilchen gegruendetes, allgemein anwendbares nachweissystem.

Country Status (7)

Country Link
US (1) US5872013A (de)
EP (1) EP0317001B1 (de)
JP (1) JP2701058B2 (de)
CA (1) CA1335254C (de)
DE (1) DE3878167T2 (de)
ES (1) ES2039025T3 (de)
GR (1) GR3007112T3 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0416764A (ja) * 1990-05-11 1992-01-21 Meiji Seika Kaisha Ltd 免疫分析法
GB9028038D0 (en) * 1990-12-24 1991-02-13 Nycomed Pharma As Test method and reagent kit therefor
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
AT402674B (de) * 1993-01-18 1997-07-25 Waldheim Pharmazeutika Gmbh Verfahren und mittel zum nachweisen von verfahren und mittel zum nachweisen von antigenen antigenen
DK0599803T3 (da) * 1992-11-23 2000-07-03 Sanochemia Pharmazeutica Aktie Fremgangsmåde til påvisning af antistoffer og antigener
AT399781B (de) * 1992-11-23 1995-07-25 Waldheim Pharmazeutika Gmbh Verfahren und reaktionsgemisch zum nachweisen von antikörpern und verfahren zum herstellen des reaktionsgemisches
US5879951A (en) 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US5939252A (en) 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US6833275B1 (en) * 1997-07-22 2004-12-21 Roche Diagnostics Gmbh Gold conjugates containing detergent
JP2002535656A (ja) * 1999-01-23 2002-10-22 ミナーヴァ・バイオテクノロジーズ・コーポレーション コロイド固定化種と非コロイド構造上の種との相互作用
JP2003515438A (ja) * 1999-12-03 2003-05-07 サーロメッド・インコーポレーテッド 金属コロイドナノ粒子のヒドキシルアミン播種
JP2003527584A (ja) * 2000-03-09 2003-09-16 ヘスカ コーポレイション 動物の免疫状態を決定するための組換え抗原の使用
WO2002004947A2 (en) * 2000-07-12 2002-01-17 University Of South Florida Spectrophotometric system and method for the identification and characterization of a particle in a bodily fluid
DE10239739B4 (de) * 2002-08-29 2006-05-11 Leica Mikrosysteme Gmbh Vorrichtung und Verfahren zur Durchführung von immunologischen Markierungstechniken für Gewebedünnschnitte
KR100893525B1 (ko) * 2002-12-09 2009-04-17 삼성전자주식회사 금 콜리이드 입자에 의하여 형성된 미세전선를 이용하는표적 분자 검출 방법
DE10309210B4 (de) * 2003-02-28 2006-04-27 Leica Mikrosysteme Gmbh Verwendung eines Transportbehälters für Objektträger zur immunologischen Markierung für Gewebedünnschnitte
DE10309211A1 (de) 2003-02-28 2004-09-09 Leica Mikrosysteme Gmbh Vorrichtung und Verfahren zur immunologischen Markierung für Gewebedünnschnitte
US7341841B2 (en) * 2003-07-12 2008-03-11 Accelr8 Technology Corporation Rapid microbial detection and antimicrobial susceptibility testing
US20120077206A1 (en) 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
CA2956645A1 (en) 2003-07-12 2005-03-31 David A. Goldberg Sensitive and rapid biodetection
EP3276349B1 (de) 2006-11-01 2019-08-07 Ventana Medical Systems, Inc. Haptene, haptenkonjugate, zusammensetzungen daraus und verfahren für ihre herstellung und verwendung
US8679858B2 (en) * 2011-01-11 2014-03-25 The Board Of Trustees Of The Leland Stanford Junior University Lanthanide mass dots: nanoparticle isotope tags
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
WO2012122314A2 (en) 2011-03-07 2012-09-13 Accelr8 Technology Corporation Rapid cell purification systems
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
AU2016243656A1 (en) 2015-03-30 2017-11-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
CN107312083A (zh) * 2017-07-12 2017-11-03 江南大学 一种氮哌酮人工抗原的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206094A (en) * 1976-06-09 1980-06-03 California Institute Of Technology Method for producing a biological reagent
NL7807532A (nl) * 1978-07-13 1980-01-15 Akzo Nv Metaal-immunotest.
US4420558A (en) * 1981-02-12 1983-12-13 Janssen Pharmaceutica N.V. Bright field light microscopic method of enumerating and characterizing subtypes of white blood cells and their precursors
GB2095258B (en) * 1981-03-19 1984-09-05 Janssen Pharmaceutica Nv A bright field light microscopic method of localizing tissue antigens
GB8331514D0 (en) * 1983-11-25 1984-01-04 Janssen Pharmaceutica Nv Visualization method
EP0167834A3 (de) * 1984-06-08 1988-03-09 Yeda Research And Development Company, Ltd. Metall enthaltende Polyaldehydmikrokugeln
GB2160673A (en) * 1984-06-20 1985-12-24 Philips Electronic Associated Electrothermal atomiser
US4752567A (en) * 1984-06-21 1988-06-21 Janssen Pharmaceutica N.V. Method of visualizing individual submicroscopic metal particles
GB8415998D0 (en) * 1984-06-22 1984-07-25 Janssen Pharmaceutica Nv Staining method
US4877647A (en) * 1986-04-17 1989-10-31 Kansas State University Research Foundation Method of coating substrates with solvated clusters of metal particles
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles

Also Published As

Publication number Publication date
DE3878167T2 (de) 1993-05-27
JPH01201160A (ja) 1989-08-14
GR3007112T3 (de) 1993-07-30
JP2701058B2 (ja) 1998-01-21
CA1335254C (en) 1995-04-18
EP0317001A1 (de) 1989-05-24
EP0317001B1 (de) 1993-02-03
US5872013A (en) 1999-02-16
ES2039025T3 (es) 1993-08-16

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