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DE3770644D1 - Monosulfactame. - Google Patents

Monosulfactame.

Info

Publication number
DE3770644D1
DE3770644D1 DE8787100056T DE3770644T DE3770644D1 DE 3770644 D1 DE3770644 D1 DE 3770644D1 DE 8787100056 T DE8787100056 T DE 8787100056T DE 3770644 T DE3770644 T DE 3770644T DE 3770644 D1 DE3770644 D1 DE 3770644D1
Authority
DE
Germany
Prior art keywords
sub
monosulfactame
formulawherein
monocyclic
exhibited
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787100056T
Other languages
English (en)
Inventor
Joseph Edward Sundeen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of DE3770644D1 publication Critical patent/DE3770644D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8787100056T 1986-01-06 1987-01-05 Monosulfactame. Expired - Fee Related DE3770644D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/816,475 US4684722A (en) 1986-01-06 1986-01-06 Monosulfactams

Publications (1)

Publication Number Publication Date
DE3770644D1 true DE3770644D1 (de) 1991-07-18

Family

ID=25220721

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787100056T Expired - Fee Related DE3770644D1 (de) 1986-01-06 1987-01-05 Monosulfactame.

Country Status (21)

Country Link
US (1) US4684722A (de)
EP (1) EP0229012B1 (de)
JP (1) JPS62158278A (de)
KR (1) KR900002244B1 (de)
AT (1) ATE64393T1 (de)
AU (3) AU602133B2 (de)
CA (1) CA1308107C (de)
DD (3) DD256700A5 (de)
DE (1) DE3770644D1 (de)
DK (1) DK3087A (de)
ES (1) ES2038127T3 (de)
FI (1) FI870030L (de)
GR (1) GR3002312T3 (de)
HU (2) HU198700B (de)
IL (1) IL81153A (de)
NO (1) NO166860C (de)
NZ (1) NZ218682A (de)
PH (1) PH23052A (de)
SU (1) SU1517762A3 (de)
YU (2) YU227886A (de)
ZA (1) ZA8771B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6452767A (en) * 1986-03-19 1989-02-28 Banyu Pharma Co Ltd 2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-vinyloxyimino)acetic acid derivative and production thereof
JPS6393796A (ja) * 1986-10-09 1988-04-25 Shin Etsu Chem Co Ltd ペプチド合成の脱保護基用薬剤
US5143913A (en) * 1988-04-04 1992-09-01 E. R. Squibb & Sons, Inc. [3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate
JPH07165740A (ja) * 1994-11-07 1995-06-27 Banyu Pharmaceut Co Ltd ２−（２−アミノチアゾリル）−２−（１−カルボキシ−１−ビニルオキシイミノ）酢酸及びその製法
US5952306A (en) * 1996-01-16 1999-09-14 Merck & Co., Inc. Integrin receptor antagonists
EP0880511A4 (de) * 1996-01-16 1999-06-16 Merck & Co Inc Integrin-rezeptor-antagonisten
US9120796B2 (en) 2013-10-02 2015-09-01 Cubist Pharmaceuticals, Inc. B-lactamase inhibitor picoline salt
CN108368040B (zh) 2015-12-15 2024-08-23 默沙东有限责任公司 二芳基单环β-内酰胺化合物及其用于治疗细菌感染的方法
RU2733402C2 (ru) 2016-03-07 2020-10-01 Мерк Шарп И Доум Корп. Бициклические арильные монобактамовые соединения и способы их применения для лечения бактериальных инфекций
US10002721B1 (en) * 2017-02-27 2018-06-19 Carling Technologies, Inc. Multiple contact circuit breaker
MX2020003581A (es) 2017-10-02 2020-07-22 Merck Sharp & Dohme Compuestos monobactamicos cromanos para el tratamiento de infecciones bacterianas.
CN113754651B (zh) * 2020-06-02 2023-04-18 中国医学科学院医药生物技术研究所 一种β-内酰胺化合物、其用途及其制备方法
CN118255695B (zh) * 2024-02-26 2025-03-14 广州艾奇西医药科技有限公司 一种β-内酰胺类化合物的中间体的纯化方法和制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU526540B2 (en) * 1976-04-12 1983-01-20 Fujisawa Pharmaceutical Co., Ltd. Oximes of substituted phenyl, thiazolyl - glyoxylic acids
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
GB1602725A (en) * 1977-04-27 1981-11-18 Glaxo Operations Ltd 7-(a-oxyiminoacetamido)-ceph-3-em-4-carboxylic acid derivatives
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4533660A (en) * 1980-10-31 1985-08-06 E. R. Squibb & Sons, Inc. Antibacterial O-sulfated β-lactam hydroxamic acids
JPS58113174A (ja) * 1981-12-26 1983-07-05 Toyama Chem Co Ltd 新規なアゼチジン誘導体またはその塩類を含有する抗菌剤
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
AU564150B2 (en) * 1982-04-30 1987-08-06 Takeda Chemical Industries Ltd. 1-sulfo-2-azetidinone derivatives
JPS58206589A (ja) * 1982-05-26 1983-12-01 Yamanouchi Pharmaceut Co Ltd ２−アゼチジノン誘導体
JPS58210060A (ja) * 1982-05-31 1983-12-07 Takeda Chem Ind Ltd ２−オキソアゼチジン誘導体、その製造法および用途
HU189290B (en) * 1982-05-31 1986-06-30 Banyu Pharmaceutical Co Ltd,Jp Process for preparing new 2-oxo-1-azetidine-sulphonic acid derivatives and pharmaceutically acceptable salts thereof, further pharmaceutical compositions containing such derivatives as active substances
EP0096296B1 (de) * 1982-06-03 1987-07-29 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft 1-Sulfo-2-oxoazetidinderivate
DE3377061D1 (en) * 1982-06-03 1988-07-21 Hoffmann La Roche Process for the preparation of 1-sulfo-2-oxoazetidine derivatives
US4704457A (en) * 1982-06-21 1987-11-03 E. R. Squibb & Sons, Inc. Process for the preparation of (3S)-3-[[[2-(protected amino)-4-thiazolyl]-oxoacetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
DE3342929A1 (de) * 1983-11-26 1985-06-05 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
NO870031L (no) 1987-07-07
DD256700A5 (de) 1988-05-18
HU198926B (en) 1989-12-28
FI870030L (fi) 1987-07-07
KR870007164A (ko) 1987-08-17
NO870031D0 (no) 1987-01-05
YU227886A (en) 1988-02-29
CA1308107C (en) 1992-09-29
SU1517762A3 (ru) 1989-10-23
US4684722A (en) 1987-08-04
DK3087D0 (da) 1987-01-05
DK3087A (da) 1987-07-07
AU5885090A (en) 1990-11-15
AU602133B2 (en) 1990-10-04
IL81153A (en) 1991-06-10
KR900002244B1 (ko) 1990-04-07
AU5885190A (en) 1990-10-25
GR3002312T3 (en) 1992-12-30
ATE64393T1 (de) 1991-06-15
IL81153A0 (en) 1987-08-31
NO166860B (no) 1991-06-03
NZ218682A (en) 1990-05-28
ES2038127T3 (es) 1993-07-16
AU617059B2 (en) 1991-11-14
HU198700B (en) 1989-11-28
JPS62158278A (ja) 1987-07-14
DD267035A5 (de) 1989-04-19
HUT44540A (en) 1988-03-28
NO166860C (no) 1991-09-11
ZA8771B (en) 1987-08-26
PH23052A (en) 1989-03-10
YU127887A (en) 1988-04-30
HUT48876A (en) 1989-07-28
AU6680886A (en) 1987-07-09
EP0229012B1 (de) 1991-06-12
EP0229012A1 (de) 1987-07-15
FI870030A0 (fi) 1987-01-05
DD267039A5 (de) 1989-04-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee