DE3729253A1 - Device for preventing infections in external fixators in bone surgery - Google Patents
Device for preventing infections in external fixators in bone surgeryInfo
- Publication number
- DE3729253A1 DE3729253A1 DE19873729253 DE3729253A DE3729253A1 DE 3729253 A1 DE3729253 A1 DE 3729253A1 DE 19873729253 DE19873729253 DE 19873729253 DE 3729253 A DE3729253 A DE 3729253A DE 3729253 A1 DE3729253 A1 DE 3729253A1
- Authority
- DE
- Germany
- Prior art keywords
- sleeve
- preventing infections
- bone surgery
- bones
- external fixators
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 208000015181 infectious disease Diseases 0.000 title claims abstract description 10
- 210000000988 bone and bone Anatomy 0.000 title claims description 11
- 238000001356 surgical procedure Methods 0.000 title description 2
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 5
- 239000000463 material Substances 0.000 claims description 6
- 239000004480 active ingredient Substances 0.000 claims description 5
- 230000003115 biocidal effect Effects 0.000 claims description 3
- 239000000499 gel Substances 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 2
- 210000004872 soft tissue Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- RDEIXVOBVLKYNT-VQBXQJRRSA-N (2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2r,3r,6s)-3-amino-6-(1-aminoethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;(2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2r,3r,6s)-3-amino-6-(aminomethyl)oxan-2-yl]o Chemical group OS(O)(=O)=O.O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC[C@@H](CN)O2)N)[C@@H](N)C[C@H]1N.O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC[C@H](O2)C(C)N)N)[C@@H](N)C[C@H]1N.O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N RDEIXVOBVLKYNT-VQBXQJRRSA-N 0.000 description 1
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000003557 bones of lower extremity Anatomy 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/60—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements for external osteosynthesis, e.g. distractors, contractors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/60—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements for external osteosynthesis, e.g. distractors, contractors
- A61B17/64—Devices extending alongside the bones to be positioned
- A61B17/6441—Bilateral fixators, i.e. with both ends of pins or wires clamped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Surgical Instruments (AREA)
Abstract
Description
Die Erfindung bezieht sich auf eine Vorrichtung zur Ver hinderung von Infektionen an den Körperaustrittsstellen von Haltestäben zum externen Fixieren gebrochener oder durchtrennter Knochen, von Knochen mit Falschgelenken oder von zu versteifenden Gelenken.The invention relates to a device for ver prevention of infections at the body exit points of holding rods for external fixation of broken or severed bones, from bones with false joints or of joints to be stiffened.
Bei einem Fixateur extern (äußeren Spanner) zur Befesti gung von komplizierten Knochenbrüchen, Knochendurchtren nungen, Knochen mit Falschgelenken oder zu versteifenden Gelenken tritt das Problem auf, daß es an den Körperaus trittsstellen der Haltestäbe zu Entzündungen durch von außen eindringende Infektionserreger kommen kann. Bisher hat man solche Infektionen nicht suffizient lokal, son dern nur durch Antibiotikagaben über den Blutkreislauf verhindern können. Es gibt zwar zur Behandlung von Infek tionen in Knochen und Wundhöhlen örtlich wirkende Ket ten, bestehend aus antibiotikaabgebenden Kugeln (Septopal-Ketten der Firma E. Merck, Darmstadt), jedoch lassen sich solche Ketten naturgemäß nicht im Bereich der Körperaustrittsstellen von Haltestäben eines Fixa teurs extern sinnvoll verwenden.With an external fixator (external tensioner) for fastening of complicated bone fractures, bone penetrations openings, bones with false joints or stiffened Joints the problem arises that it affects the body points of contact of the holding rods to inflammation from infectious agents can enter the outside. So far such infections are not sufficiently local, son but only by giving antibiotics via the bloodstream can prevent. Although there is to treat infectiousness ions in bones and wound cavities localized ket consisting of antibiotic-releasing balls (Septopal chains from E. Merck, Darmstadt), however such chains are naturally not in the range the body exit points of fixa support rods Use expensive externally.
Der Erfindung liegt die Aufgabe zugrunde, eine Vorrich tung zu entwickeln, mit der das Infektionsrisiko im Be reich der Körperaustrittsstellen von Haltestäben von äußeren Spannern örtlich suffizient bekämpft werden kann. The invention has for its object a Vorrich to develop with which the risk of infection in the Be range of body exits from holding bars of local tensioners are adequately controlled can.
Diese Aufgabe wird erfindungsgemäß dadurch gelöst, daß es sich bei der Vorrichtung jeweils um eine den Halte stab einfassende Manschette oder Hülse aus einem Werk stoff handelt, der einen das Infektionsrisiko mindernden Wirkstoff abzugeben vermag.This object is achieved in that it is in each case a holding device rod-enclosing sleeve or sleeve from a factory is a substance that reduces the risk of infection Active ingredient is able to deliver.
Durch diese Manschette oder Hülse erreicht man, daß der das Infektionsrisiko mindernde Wirkstoff genau dort und zwar kontinuierlich über einen genügend langen Zeitraum abgegeben wird, wo das Infektionsrisiko besteht. Man kann deshalb mit geringen Wirkstoffmengen arbeiten, so daß der Körper nur in vermindertem Maße durch den Wirk stoff selbst beansprucht wird und entsprechenden Neben wirkungen ausgesetzt ist. Der Wirkstoff braucht nicht den Wirkort über den Weg des Blutkreislaufes zu errei chen, er braucht also weder über den Magen-Darm-Trakt noch durch Injektion zugeführt zu werden.Through this cuff or sleeve you can achieve that the infection risk reducing agent right there and continuously over a sufficiently long period of time is given where there is a risk of infection. Man can therefore work with small amounts of active ingredient, so that the body works only to a lesser extent material itself is claimed and the corresponding ancillary is exposed to effects. The active ingredient does not need to reach the site of action via the path of the blood circulation Chen, so he does not need the gastrointestinal tract still to be delivered by injection.
Von besonderem Vorteil ist es, wenn die Manschette oder Hülse aus einem ein Antibiotikum abgebenden Werkstoff be steht, welcher zum Beispiel als sogenannter Knochenze ment (Polymethylmetacrylat) bekannt ist. Solche Werkstof fe werden für andere Anwendungsfälle, beispielsweise als Kittsubstanz beim Einpflanzen von künstlichen Gelenken, verwendet und zum Beispiel von der Firma E. Merck in Darmstadt unter der Bezeichnung "Refobacin-Palacos" ver trieben und sind zugelassen. Sie können daher ohne Risi ken auch für den neuen Verwendungszweck eingesetzt wer den.It is particularly advantageous if the cuff or Sleeve made of an antibiotic material stands, which for example as a so-called bone zen ment (polymethyl methacrylate) is known. Such material fe are used for other applications, such as Cement substance when implanting artificial joints, used and for example by E. Merck in Darmstadt under the name "Refobacin-Palacos" ver driven and are approved. You can therefore without Risi ken also used for the new purpose the.
Zur weiteren Erläuterung der Erfindung wird nunmehr auf die Zeichnung Bezug genommen. Diese zeigt einen Schnitt durch einen Extremitätenabschnitt mit fixiertem äußeren Spanner (Fixateur extern) mit in diesem Fall zur besse ren Übersichtlichkeit nur zwei intraossär liegenden Stä ben. To further explain the invention, reference is now made to referred to the drawing. This shows a cut through a limb section with a fixed outer Tensioner (external fixator) to be better in this case For clarity, only two intraosseous columns ben.
In der Zeichnung ist ein Teilbereich eines gebrochenen Extremitätenknochens 1 mit dem ihn umgebenden Weichgewe be dargestellt. Die beiden den Knochen durchbohrenden Haltestäbe 5 sind durch außen liegende Verspannungsstäbe 3 verbunden. Es handelt sich bis hierher um bekannte und sehr häufig verwendete Techniken und Methoden im Bereich der Knochenchirurgie.In the drawing, a portion of a broken limb bone 1 is shown with the surrounding soft tissue be. The two holding rods 5 piercing the bone are connected by external tension rods 3 . So far, these are known and very frequently used techniques and methods in the field of bone surgery.
Wichtig für die Erfindung ist, daß an den Austrittsstel len der Haltestäbe 5 aus dem Weichgewebe 2 auf ihm jeweils eine ein- oder mehrteilige Manschette oder Hülse 4 plaziert wird, die aus einem Werkstoff besteht, der Antibiotika kontinuierlich abzugeben vermag. Ein geeig neter Werkstoff wird beispielsweise von der Firma E. Merck Darmstadt unter der Bezeichnung "Refobacin-Pala cos angeboten.It is important for the invention that at the exit points len of the holding rods 5 from the soft tissue 2 , a one- or multi-part sleeve or sleeve 4 is placed on it, which consists of a material that is able to deliver antibiotics continuously. A suitable material is offered, for example, by E. Merck Darmstadt under the name "Refobacin-Pala cos.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873729253 DE3729253A1 (en) | 1987-09-02 | 1987-09-02 | Device for preventing infections in external fixators in bone surgery |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873729253 DE3729253A1 (en) | 1987-09-02 | 1987-09-02 | Device for preventing infections in external fixators in bone surgery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3729253A1 true DE3729253A1 (en) | 1989-03-23 |
Family
ID=6335016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19873729253 Withdrawn DE3729253A1 (en) | 1987-09-02 | 1987-09-02 | Device for preventing infections in external fixators in bone surgery |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE3729253A1 (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19611881C1 (en) * | 1996-03-26 | 1997-06-26 | Ewald Rueter | External fixture system for bone fracture, with screws and cross pieces |
| WO1998044967A1 (en) | 1997-04-04 | 1998-10-15 | Mediport Biotechnik Gmbh | Sealing device for an element to be introduced through the skin into a human or animal body |
| DE19837762A1 (en) * | 1998-06-13 | 2000-01-20 | Pfefferkorn & Co | Two-part pressure body with guide bar |
| EP1466566A1 (en) | 2003-04-09 | 2004-10-13 | Affeld, Klaus, Prof. Dr. Ing. | Infection prevention device for transcutaneous implants |
| US9642658B2 (en) | 2008-10-15 | 2017-05-09 | Orthoclip Llc | Device and method for delivery of therapeutic agents via internal implants |
| US10010350B2 (en) | 2016-06-14 | 2018-07-03 | Stryker European Holdings I, Llc | Gear mechanisms for fixation frame struts |
| US10874433B2 (en) | 2017-01-30 | 2020-12-29 | Stryker European Holdings I, Llc | Strut attachments for external fixation frame |
| US11529238B2 (en) | 2019-09-12 | 2022-12-20 | DePuy Synthes Products, Inc. | Sleeve for percutaneous device and methods of production and use thereof |
| US11806050B2 (en) | 2020-09-21 | 2023-11-07 | DePuy Synthes Products, Inc. | Tension isolating adjustable adapter for external fixation and methods of production and use thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1307055A (en) * | 1970-10-01 | 1973-02-14 | Tecna Corp | Percutaneous lead device |
| DE2806609B1 (en) * | 1978-02-16 | 1979-07-05 | Haerle Anton | Osteosynthesis aids |
| DE2912852A1 (en) * | 1979-03-30 | 1980-10-16 | Erich Prof Dr Med D Matouschek | Lubricating film for catheter - comprises non-conducting polymer with pH 5 6.8 |
| DE3206726A1 (en) * | 1982-02-25 | 1983-09-01 | Merck Patent Gmbh, 6100 Darmstadt | PHARMACADEPOT |
| WO1984001721A1 (en) * | 1982-11-05 | 1984-05-10 | Baxter Travenol Lab | Antimicrobial compositions |
| DE3331562A1 (en) * | 1983-09-01 | 1985-03-21 | Orthoplant Vertriebs-GmbH, 2800 Bremen | Metal endoprosthesis and method for the production thereof |
| DE3533369A1 (en) * | 1985-09-19 | 1987-03-19 | Alois Prof Dr Med Bloemer | ANTIBIOTIC CONTAINER AND ITS USE AS SURGICAL PLASTIC MATERIAL |
-
1987
- 1987-09-02 DE DE19873729253 patent/DE3729253A1/en not_active Withdrawn
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1307055A (en) * | 1970-10-01 | 1973-02-14 | Tecna Corp | Percutaneous lead device |
| DE2806609B1 (en) * | 1978-02-16 | 1979-07-05 | Haerle Anton | Osteosynthesis aids |
| DE2912852A1 (en) * | 1979-03-30 | 1980-10-16 | Erich Prof Dr Med D Matouschek | Lubricating film for catheter - comprises non-conducting polymer with pH 5 6.8 |
| DE3206726A1 (en) * | 1982-02-25 | 1983-09-01 | Merck Patent Gmbh, 6100 Darmstadt | PHARMACADEPOT |
| WO1984001721A1 (en) * | 1982-11-05 | 1984-05-10 | Baxter Travenol Lab | Antimicrobial compositions |
| DE3331562A1 (en) * | 1983-09-01 | 1985-03-21 | Orthoplant Vertriebs-GmbH, 2800 Bremen | Metal endoprosthesis and method for the production thereof |
| DE3533369A1 (en) * | 1985-09-19 | 1987-03-19 | Alois Prof Dr Med Bloemer | ANTIBIOTIC CONTAINER AND ITS USE AS SURGICAL PLASTIC MATERIAL |
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19611881C1 (en) * | 1996-03-26 | 1997-06-26 | Ewald Rueter | External fixture system for bone fracture, with screws and cross pieces |
| WO1998044967A1 (en) | 1997-04-04 | 1998-10-15 | Mediport Biotechnik Gmbh | Sealing device for an element to be introduced through the skin into a human or animal body |
| DE19714907C1 (en) * | 1997-04-04 | 1998-10-29 | Mediport Biotech Gmbh | Sealing device for a skin passage element to be inserted into a human or animal body |
| DE19837762A1 (en) * | 1998-06-13 | 2000-01-20 | Pfefferkorn & Co | Two-part pressure body with guide bar |
| DE19837762C2 (en) * | 1998-06-13 | 2002-08-29 | Pfefferkorn & Co | Device for an external fixator with a holding device for a wound care agent |
| EP1466566A1 (en) | 2003-04-09 | 2004-10-13 | Affeld, Klaus, Prof. Dr. Ing. | Infection prevention device for transcutaneous implants |
| DE10316726A1 (en) * | 2003-04-09 | 2005-01-13 | Klaus Prof. Dr.-Ing. Affeld | Infection protection device for endoexo implants |
| DE10316726B4 (en) * | 2003-04-09 | 2008-03-27 | Klaus Prof. Dr.-Ing. Affeld | Infection protection device for an endoexo implant |
| US9642658B2 (en) | 2008-10-15 | 2017-05-09 | Orthoclip Llc | Device and method for delivery of therapeutic agents via internal implants |
| US10010350B2 (en) | 2016-06-14 | 2018-07-03 | Stryker European Holdings I, Llc | Gear mechanisms for fixation frame struts |
| US11504160B2 (en) | 2016-06-14 | 2022-11-22 | Stryker European Operations Holdings Llc | Gear mechanisms for fixation frame struts |
| US11974781B2 (en) | 2016-06-14 | 2024-05-07 | Stryker European Operations Holdings Llc | Gear mechanisms for fixation frame struts |
| US12201325B2 (en) | 2016-06-14 | 2025-01-21 | Stryker European Operations Holdings Llc | Gear mechanisms for fixation frame struts |
| US10874433B2 (en) | 2017-01-30 | 2020-12-29 | Stryker European Holdings I, Llc | Strut attachments for external fixation frame |
| US11723690B2 (en) | 2017-01-30 | 2023-08-15 | Stryker European Operations Holdings Llc | Strut attachments for external fixation frame |
| US11529238B2 (en) | 2019-09-12 | 2022-12-20 | DePuy Synthes Products, Inc. | Sleeve for percutaneous device and methods of production and use thereof |
| US11806050B2 (en) | 2020-09-21 | 2023-11-07 | DePuy Synthes Products, Inc. | Tension isolating adjustable adapter for external fixation and methods of production and use thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OM8 | Search report available as to paragraph 43 lit. 1 sentence 1 patent law | ||
| 8139 | Disposal/non-payment of the annual fee |