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DE3688983D1 - Faktor IX-Protein. - Google Patents

Faktor IX-Protein.

Info

Publication number
DE3688983D1
DE3688983D1 DE91200265T DE3688983T DE3688983D1 DE 3688983 D1 DE3688983 D1 DE 3688983D1 DE 91200265 T DE91200265 T DE 91200265T DE 3688983 T DE3688983 T DE 3688983T DE 3688983 D1 DE3688983 D1 DE 3688983D1
Authority
DE
Germany
Prior art keywords
protein
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE91200265T
Other languages
English (en)
Other versions
DE3688983T2 (de
Inventor
Donald Stewart Anson
George Gow Brownlee
Ian Martin Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858506767A external-priority patent/GB8506767D0/en
Priority claimed from GB858515416A external-priority patent/GB8515416D0/en
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Application granted granted Critical
Publication of DE3688983D1 publication Critical patent/DE3688983D1/de
Publication of DE3688983T2 publication Critical patent/DE3688983T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/644Coagulation factor IXa (3.4.21.22)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21022Coagulation factor IXa (3.4.21.22)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE19863688983 1985-03-15 1986-03-12 Faktor IX-Protein. Expired - Lifetime DE3688983T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858506767A GB8506767D0 (en) 1985-03-15 1985-03-15 Factor 1x protein
GB858515416A GB8515416D0 (en) 1985-06-18 1985-06-18 Factor ix protein

Publications (2)

Publication Number Publication Date
DE3688983D1 true DE3688983D1 (de) 1993-10-07
DE3688983T2 DE3688983T2 (de) 1994-02-17

Family

ID=26288979

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19863688983 Expired - Lifetime DE3688983T2 (de) 1985-03-15 1986-03-12 Faktor IX-Protein.
DE8686301791T Expired - Lifetime DE3684947D1 (de) 1985-03-15 1986-03-12 Faktor-ix-protein.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8686301791T Expired - Lifetime DE3684947D1 (de) 1985-03-15 1986-03-12 Faktor-ix-protein.

Country Status (3)

Country Link
EP (2) EP0430930B1 (de)
JP (1) JPH082300B2 (de)
DE (2) DE3688983T2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3684546D1 (de) * 1985-04-22 1992-04-30 Genetics Inst Herstellung mit hoher leistung des aktivfaktors ix.
FR2599752B1 (fr) * 1986-06-10 1989-11-03 Transgene Sa Variants de l'alpha1- antitrypsine utiles notamment comme inhibiteurs de la kallikreine
FR2600334B1 (fr) * 1986-06-23 1989-05-12 Transgene Sa Vecteurs d'integration dans les cellules eucaryotes assurant l'expression du facteur ix, lignees celullaires obtenues et procede pour leur preparation
JPH01502080A (ja) * 1986-11-17 1989-07-27 ニュー・イングランド・メディカル・センター 組み換えビタミンk依存性蛋白質のガンマカルボキシル化の増強
US5648254A (en) * 1988-01-15 1997-07-15 Zymogenetics, Inc. Co-expression in eukaryotic cells
US5120537A (en) * 1989-06-14 1992-06-09 Oklahoma Medical Research Foundation Factor xa based anticoagulant compositions
GB9122609D0 (en) * 1991-10-24 1991-12-04 Brownlee George G Improvements relating to the treatment of haemophilia
CA2198589C (en) * 1994-09-08 2010-06-15 Florian M. Wurm Methods for calcium phosphate transfection
US5484720A (en) * 1994-09-08 1996-01-16 Genentech, Inc. Methods for calcium phosphate transfection
DE4435520A1 (de) * 1994-10-04 1996-04-11 Immuno Ag Verfahren zur Trennung von rekombinantem pro-Faktor IX von rekombinantem Faktor IX
JP2002531093A (ja) 1998-12-01 2002-09-24 アベンティス、パストゥール、リミテッド クラミジア抗原および対応するdna断片ならびにその使用
US7125841B2 (en) 2000-11-14 2006-10-24 The University Of Texas Systems Mutant human factor IX with an increased resistance to inhibition by heparin
JP4855074B2 (ja) * 2003-09-30 2012-01-18 一般財団法人化学及血清療法研究所 高純度血液凝固ix因子調製物およびその精製方法
US7829745B1 (en) 2009-08-18 2010-11-09 Corning Incorporated Methods for selectively synthesizing 1-aryl-2-tetralones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125409B (en) * 1982-08-04 1985-11-13 Nat Res Dev Genetic engineering
FR2564106B1 (fr) * 1984-05-09 1988-04-22 Transgene Sa Vecteurs d'expression du facteur ix, cellules transformees par ces vecteurs et procede de preparation du facteur ix.

Also Published As

Publication number Publication date
EP0195592A3 (en) 1987-06-24
JPH082300B2 (ja) 1996-01-17
EP0195592A2 (de) 1986-09-24
EP0430930B1 (de) 1993-09-01
JPS61263926A (ja) 1986-11-21
DE3684947D1 (de) 1992-05-27
EP0195592B1 (de) 1992-04-22
EP0430930A1 (de) 1991-06-05
DE3688983T2 (de) 1994-02-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition