DE3685895D1 - Dosierungssystem fuer transdermale absorption von arzneimittelwirkstoffen. - Google Patents
Dosierungssystem fuer transdermale absorption von arzneimittelwirkstoffen.Info
- Publication number
- DE3685895D1 DE3685895D1 DE8686301330T DE3685895T DE3685895D1 DE 3685895 D1 DE3685895 D1 DE 3685895D1 DE 8686301330 T DE8686301330 T DE 8686301330T DE 3685895 T DE3685895 T DE 3685895T DE 3685895 D1 DE3685895 D1 DE 3685895D1
- Authority
- DE
- Germany
- Prior art keywords
- active substances
- dosing system
- transdermal absorption
- drug active
- layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000010521 absorption reaction Methods 0.000 title 1
- 239000013543 active substance Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000011159 matrix material Substances 0.000 abstract 2
- 239000002998 adhesive polymer Substances 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 229920003168 pharmaceutical polymer Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70519485A | 1985-02-25 | 1985-02-25 | |
US77096885A | 1985-08-30 | 1985-08-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3685895D1 true DE3685895D1 (de) | 1992-08-13 |
DE3685895T2 DE3685895T2 (de) | 1992-12-24 |
Family
ID=27107455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686301330T Expired - Lifetime DE3685895T2 (de) | 1985-02-25 | 1986-02-24 | Dosierungssystem fuer transdermale absorption von arzneimittelwirkstoffen. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0196769B1 (de) |
JP (1) | JP2511405B2 (de) |
AT (1) | ATE77962T1 (de) |
CA (1) | CA1272445A (de) |
DE (1) | DE3685895T2 (de) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4806341A (en) * | 1985-02-25 | 1989-02-21 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration |
US4818540A (en) * | 1985-02-25 | 1989-04-04 | Rutgers, The State University Of New Jersey | Transdermal fertility control system and process |
US4883669A (en) * | 1985-02-25 | 1989-11-28 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration |
CA1288698C (en) * | 1985-08-30 | 1991-09-10 | Yie W. Chien | Transdermal anti-anginal pharmaceutical dosage |
US4764381A (en) * | 1985-12-06 | 1988-08-16 | Key Pharmaceuticals, Inc. | Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol |
US5145682A (en) * | 1986-05-30 | 1992-09-08 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration |
US5560922A (en) * | 1986-05-30 | 1996-10-01 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process |
AU607172B2 (en) * | 1986-12-22 | 1991-02-28 | Cygnus, Inc. | Diffusion matrix for transdermal drug administration |
CN1021196C (zh) * | 1986-12-29 | 1993-06-16 | 新泽西州州立大学(鲁杰斯) | 透皮雌激素/孕激素药剂单元、系统及方法 |
US4788062A (en) * | 1987-02-26 | 1988-11-29 | Alza Corporation | Transdermal administration of progesterone, estradiol esters, and mixtures thereof |
US4746515A (en) * | 1987-02-26 | 1988-05-24 | Alza Corporation | Skin permeation enhancer compositions using glycerol monolaurate |
EP0282156B1 (de) * | 1987-03-09 | 1991-04-17 | Alza Corporation | Zusammensetzung zur Vorbeugung einer Kontaktallergie durch gleichzeitiges Verabreichen eines Kortikosteroids mit einem sensiblisierenden Arzneistoff |
US5000956A (en) * | 1987-03-09 | 1991-03-19 | Alza Corporation | Prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug |
US5077054A (en) * | 1987-03-09 | 1991-12-31 | Alza Corporation | Prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug |
US5171576A (en) * | 1987-03-09 | 1992-12-15 | Alza Corporation | Prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug |
US5118509A (en) * | 1987-03-09 | 1992-06-02 | Alza Corporation | Inducing skin tolerance to a sensitizing drug |
CH674618A5 (de) * | 1987-04-02 | 1990-06-29 | Ciba Geigy Ag | |
US5045553A (en) * | 1987-06-24 | 1991-09-03 | Fujisawa Pharmaceutical Company, Ltd. | Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter |
DK158336C (da) * | 1987-09-22 | 1990-10-01 | Coloplast As | Forbindsmateriale til behandling af saar samt smaalegemer til brug ved fremstilling deraf |
US4898920A (en) * | 1987-10-15 | 1990-02-06 | Dow Corning Corporation | Adhesive compositions, controlled release compositions and transdermal delivery device |
US5028431A (en) * | 1987-10-29 | 1991-07-02 | Hercon Laboratories Corporation | Article for the delivery to animal tissue of a pharmacologically active agent |
JPH01265021A (ja) * | 1987-10-29 | 1989-10-23 | Hercon Lab Corp | 薬理学的活性物質を含有する組成物を動物組織に制御放出および供給するための物品 |
US4863738A (en) * | 1987-11-23 | 1989-09-05 | Alza Corporation | Skin permeation enhancer compositions using glycerol monooleate |
IE62871B1 (en) * | 1988-03-08 | 1995-03-08 | Warner Lambert Co | Compositions with enhanced penetration |
US4840796A (en) * | 1988-04-22 | 1989-06-20 | Dow Corning Corporation | Block copolymer matrix for transdermal drug release |
IL92537A (en) * | 1988-12-15 | 1994-04-12 | Riker Laboratories Inc | Topical preparations and dermal systems containing 1-isobutyl-H1-imidazo [C-4,5] quinoline-4-amine |
DE3910543A1 (de) * | 1989-04-01 | 1990-10-11 | Lohmann Therapie Syst Lts | Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung |
JP2512805B2 (ja) * | 1989-07-14 | 1996-07-03 | 積水化学工業株式会社 | ケトチフェン経皮吸収製剤 |
FR2650747B1 (fr) * | 1989-08-11 | 1994-02-11 | Oreal | Film composite pour traitement cutane local et procedes de fabrication correspondants |
US5262165A (en) * | 1992-02-04 | 1993-11-16 | Schering Corporation | Transdermal nitroglycerin patch with penetration enhancers |
CA2064845A1 (en) * | 1989-08-17 | 1991-02-18 | Sharad K. Govil | Transdermal nitroglycerin patch with penetration enhancers |
EP0425968A3 (en) * | 1989-10-23 | 1992-01-22 | G.D. Searle & Co. | Novel multiple layer transdermal drug administration system |
DE69009946T2 (de) * | 1989-12-04 | 1994-11-03 | Searle & Co | System zur transdermalen Albuterol Applikation. |
AU653156B2 (en) * | 1990-06-14 | 1994-09-22 | Dermamed | Transdermal administration to humans and animals |
FR2664815B1 (fr) * | 1990-07-23 | 1994-11-04 | Adir | Systeme matriciel autoadhesif pour la liberation prolongee du piribedil par voie transcutanee. |
BR9105371A (pt) * | 1990-12-20 | 1992-08-25 | Lilly Co Eli | Formulacao apropriada para a administracao transdermica de dobutamina e processo para aumentar a contratilidade cardiaca |
US5518734A (en) * | 1991-09-25 | 1996-05-21 | Beta Pharmaceuticals Co. | Transdermal delivery system for estradiol and process for manufacturing said device |
US5705185A (en) * | 1991-09-25 | 1998-01-06 | Beta Pharmaceuticals Co. | Transdermal delivery of estradiol and process for manufacturing said device |
IL116539A (en) * | 1995-01-06 | 2002-02-10 | Noven Pharma | Preparations given through the skin of unstable anti-acid drugs |
US6024974A (en) * | 1995-01-06 | 2000-02-15 | Noven Pharmaceuticals, Inc. | Composition and methods for transdermal delivery of acid labile drugs |
IL122432A (en) * | 1995-06-07 | 2000-07-16 | Cygnus Therapeutic Systems | Transdermal patch for preventing ovulation |
US6063398A (en) * | 1995-09-20 | 2000-05-16 | L'oreal | Cosmetic or dermopharmaceutical patch containing, in an anhydrous polymeric matrix, at least one active compound which is, in particular, unstable in oxidizing mediums, and at least one water-absorbing agent |
FR2738744B1 (fr) * | 1995-09-20 | 1997-10-24 | Oreal | Patch cosmetique ou dermo-pharmaceutique contenant dans une matrice polymerique au moins un compose actif en particulier instable en milieu oxydant et au moins un agent hydro-absorbant |
DE19705138A1 (de) * | 1997-02-11 | 1998-08-13 | Lohmann Therapie Syst Lts | Dehnbares transdermales therapeutisches System |
BR0012152A (pt) | 1999-07-02 | 2002-03-12 | Lohmann Therapie Syst Lts | Sistema de microrreservatórios na base de polissiloxanos e solventes ambifìlicos |
DE19958554C2 (de) * | 1999-07-02 | 2002-06-13 | Lohmann Therapie Syst Lts | Mikroreservoirsystem auf Basis von Polysiloxanen und ambiphilen Lösemitteln und ihre Herstellung |
US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
SE0300693D0 (sv) * | 2003-03-14 | 2003-03-14 | Sca Hygiene Prod Ab | Bärare för tillsatsämne vid absorberande alster |
US7601882B2 (en) | 2003-03-14 | 2009-10-13 | Sca Hygiene Products Ab | Carrier for additive in an absorbent article |
CA2624788C (en) | 2005-10-12 | 2011-04-19 | Unimed Pharmaceuticals, Llc | Improved testosterone gel and method of use |
FR2934162B1 (fr) * | 2008-07-23 | 2012-08-17 | Millet Innovation | Timbre dermique pour l'application d'actifs secs |
KR101239150B1 (ko) * | 2012-02-28 | 2013-03-06 | 에스케이케미칼주식회사 | 도네페질-함유 경피흡수제제 및 그의 제조방법 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3797494A (en) * | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
US4316893A (en) * | 1975-06-19 | 1982-02-23 | Nelson Research & Development Co. | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
US4286592A (en) * | 1980-02-04 | 1981-09-01 | Alza Corporation | Therapeutic system for administering drugs to the skin |
JPS5928533B2 (ja) * | 1980-06-14 | 1984-07-13 | 日東電工株式会社 | 貼付剤 |
US4336243A (en) * | 1980-08-11 | 1982-06-22 | G. D. Searle & Co. | Transdermal nitroglycerin pad |
JPS5843368B2 (ja) * | 1980-10-30 | 1983-09-27 | 日東電工株式会社 | 消炎鎮痛貼付剤 |
JPS57116011A (en) * | 1981-01-08 | 1982-07-19 | Nitto Electric Ind Co Ltd | Pharmaceutical preparation |
JPS6059207B2 (ja) * | 1981-03-13 | 1985-12-24 | 日東電工株式会社 | 複合製剤の製法 |
JPS58208216A (ja) * | 1982-05-28 | 1983-12-03 | Nitto Electric Ind Co Ltd | テ−プ製剤 |
DK243084A (da) * | 1983-05-26 | 1984-11-27 | Takeda Chemical Industries Ltd | Perkutane farmaceutiske praeparater til udvortes brug |
-
1986
- 1986-02-24 EP EP86301330A patent/EP0196769B1/de not_active Expired - Lifetime
- 1986-02-24 CA CA000502499A patent/CA1272445A/en not_active Expired
- 1986-02-24 AT AT86301330T patent/ATE77962T1/de not_active IP Right Cessation
- 1986-02-24 DE DE8686301330T patent/DE3685895T2/de not_active Expired - Lifetime
- 1986-02-25 JP JP61040159A patent/JP2511405B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0196769A2 (de) | 1986-10-08 |
JP2511405B2 (ja) | 1996-06-26 |
EP0196769A3 (en) | 1988-12-07 |
JPS61246122A (ja) | 1986-11-01 |
CA1272445A (en) | 1990-08-07 |
DE3685895T2 (de) | 1992-12-24 |
ATE77962T1 (de) | 1992-07-15 |
EP0196769B1 (de) | 1992-07-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |