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DE3875705D1 - Carbidopa-levodopa-zusammensetzung mit gesteuerter freigabe. - Google Patents

Carbidopa-levodopa-zusammensetzung mit gesteuerter freigabe.

Info

Publication number
DE3875705D1
DE3875705D1 DE8888202760T DE3875705T DE3875705D1 DE 3875705 D1 DE3875705 D1 DE 3875705D1 DE 8888202760 T DE8888202760 T DE 8888202760T DE 3875705 T DE3875705 T DE 3875705T DE 3875705 D1 DE3875705 D1 DE 3875705D1
Authority
DE
Germany
Prior art keywords
controlled release
carbidopa
levodopa
levodopa composition
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888202760T
Other languages
English (en)
Other versions
DE3875705T2 (de
Inventor
Robert E Dempski
Scott A Reines
Edward C Scholtz
Donald W Nibbelink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26829626&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3875705(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3875705D1 publication Critical patent/DE3875705D1/de
Publication of DE3875705T2 publication Critical patent/DE3875705T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE8888202760T 1987-12-11 1988-12-02 Carbidopa-levodopa-zusammensetzung mit gesteuerter freigabe. Expired - Lifetime DE3875705T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13160187A 1987-12-11 1987-12-11
US07/223,861 US4832957A (en) 1987-12-11 1988-07-25 Controlled release combination of carbidopa/levodopa

Publications (2)

Publication Number Publication Date
DE3875705D1 true DE3875705D1 (de) 1992-12-10
DE3875705T2 DE3875705T2 (de) 1993-05-13

Family

ID=26829626

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888202760T Expired - Lifetime DE3875705T2 (de) 1987-12-11 1988-12-02 Carbidopa-levodopa-zusammensetzung mit gesteuerter freigabe.

Country Status (15)

Country Link
US (1) US4832957A (de)
EP (1) EP0320051B1 (de)
JP (1) JPH0667830B2 (de)
KR (1) KR890009377A (de)
AT (1) ATE81970T1 (de)
AU (1) AU616449B2 (de)
CA (1) CA1318602C (de)
DE (1) DE3875705T2 (de)
DK (1) DK170515B1 (de)
ES (1) ES2052691T3 (de)
GR (1) GR3006220T3 (de)
HK (1) HK7997A (de)
IE (1) IE61547B1 (de)
IL (1) IL88563A0 (de)
PT (1) PT89157B (de)

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DE4101873C2 (de) 1991-01-23 1993-12-09 Isis Pharma Gmbh Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände
US5624960A (en) * 1991-01-23 1997-04-29 Isis Pharma Gmbh Orally administrable drugs for the treatment of central dopamine deficiency conditions
HU209564B (en) * 1991-01-30 1994-07-28 Egyt Gyogyszervegyeszeti Gyar Process for producing rapide tablets containing levodopa and carbidopa
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
DE4226753A1 (de) * 1992-08-13 1994-02-17 Basf Ag Wirkstoffe enthaltende Zubereitungen in Form fester Teilchen
SE9203594D0 (sv) * 1992-11-30 1992-11-30 Christer Nystroem Laekemedel i dispersa system
FR2725624B1 (fr) * 1994-10-14 1997-01-17 Jouveinal Inst Rech Procede de preparation de formes pharmaceutiques a liberation controlee
US7179486B1 (en) 1997-04-01 2007-02-20 Nostrum Pharmaceuticals, Inc. Process for preparing sustained release tablets
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US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
US20040121014A1 (en) * 1999-03-22 2004-06-24 Control Delivery Systems, Inc. Method for treating and/or preventing retinal diseases with sustained release corticosteroids
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US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
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US20060159753A1 (en) * 2004-12-27 2006-07-20 Eisai Co. Ltd. Matrix type sustained-release preparation containing basic drug or salt thereof
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JP5517453B2 (ja) * 2005-07-26 2014-06-11 ノヴィファーマ，エス．アー． Ｃｏｍｔ阻害剤
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US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
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EP1945188A2 (de) * 2005-11-07 2008-07-23 Teva Pharmaceutical Industries Ltd. Levodopa-zusammensetzung
CN101304764B (zh) 2005-11-11 2012-12-05 旭化成化学株式会社 控释固体制剂
US20080131492A1 (en) * 2006-06-23 2008-06-05 Spherics, Inc. Dosage forms for movement disorder treatment
KR100756977B1 (ko) * 2006-09-28 2007-09-07 한국전자통신연구원 휴대 인터넷 망과 인터넷 프로토콜 멀티미디어 서브시스템연동망에서 단말의 핸드오버 방법 및 장치
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KR100892220B1 (ko) * 2007-07-02 2009-04-07 순천대학교 산학협력단 근사기법을 이용한 태양광 발전의 mppt 제어시스템
KR101451564B1 (ko) 2007-12-28 2014-11-04 임팩스 라보라토리즈, 인코포레이티드 레보도파 방출 제어형 제제 및 이의 용도
JP2012500221A (ja) * 2008-08-15 2012-01-05 ディポメド，インコーポレイティド Ｃｎｓ障害の処理及び予防のための胃保持性医薬組成物
JP2013515741A (ja) * 2009-12-23 2013-05-09 サイヴィーダ ユーエス，インコーポレイテッド 持続放出性送達デバイス
EP2508174A1 (de) 2011-04-06 2012-10-10 Ljiljana Sovic Brkicic Pharmazeutische Zusammensetzung
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US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
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US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
ES2836325T3 (es) 2014-03-13 2021-06-24 Neuroderm Ltd Composiciones del inhibidor de la dopa descarboxilasa
CA3030089C (en) 2016-07-11 2024-04-23 Contera Pharma Aps Pulsatile drug delivery system for treating morning akinesia
US11464756B1 (en) 2017-05-19 2022-10-11 Jerry Darm Mecuna pruriens, L-DOPA and 5-HTP based dietary supplements, pharmaceutical formulations and uses thereof
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
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Also Published As

Publication number Publication date
KR890009377A (ko) 1989-08-01
ES2052691T3 (es) 1994-07-16
DK170515B1 (da) 1995-10-09
IE883679L (en) 1989-06-11
IL88563A0 (en) 1989-07-31
EP0320051B1 (de) 1992-11-04
DE3875705T2 (de) 1993-05-13
AU616449B2 (en) 1991-10-31
IE61547B1 (en) 1994-11-16
HK7997A (en) 1997-01-24
US4832957A (en) 1989-05-23
AU2673388A (en) 1989-06-15
DK685888A (da) 1989-07-25
PT89157A (pt) 1989-12-29
ATE81970T1 (de) 1992-11-15
PT89157B (pt) 1993-06-30
EP0320051A1 (de) 1989-06-14
GR3006220T3 (de) 1993-06-21
JPH02209A (ja) 1990-01-05
JPH0667830B2 (ja) 1994-08-31
DK685888D0 (da) 1988-12-09
CA1318602C (en) 1993-06-01

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