|
JPH0775593A
(ja)
*
|
1993-09-08 |
1995-03-20 |
Suntory Ltd |
蛋白質の製造方法
|
|
EP0827946A1
(de)
*
|
1996-09-04 |
1998-03-11 |
Vrije Universiteit Brussel |
Inhibitoren der Differenzierung von Zellen, insbesondere von Kupffer-Sternzellen
|
|
WO1998029108A2
(en)
*
|
1996-12-30 |
1998-07-09 |
The Johns Hopkins University School Of Medicine |
Compositions and methods for restoring a normal pattern of imprinting to cells
|
|
EP1332756A3
(de)
*
|
1996-12-30 |
2003-12-10 |
The Johns Hopkins University School Of Medicine |
Zusammensetzungen und Methoden zur Wiederherstellung einer normalen Zellprägung
|
|
US6387673B1
(en)
*
|
1997-05-01 |
2002-05-14 |
The Salk Institute For Biological Studies |
Compounds useful for the modulation of processes mediated by nuclear hormone receptors, methods for the identification and use of such compounds
|
|
AUPO721997A0
(en)
*
|
1997-06-06 |
1997-07-03 |
Queensland Institute Of Medical Research, The |
Anticancer compounds
|
|
US6518012B1
(en)
|
1999-04-02 |
2003-02-11 |
Health Research, Inc. |
Method for regulating the expression of MHC antigens and CD40 by inhibitors of histone deacetylation
|
|
US6544957B2
(en)
|
2000-01-04 |
2003-04-08 |
The Johns Hopkins University |
Methods and reagents for facilitating transcription
|
|
AU2002243231A1
(en)
*
|
2000-11-21 |
2002-07-24 |
Wake Forest University |
Method of treating autoimmune diseases
|
|
AR035659A1
(es)
*
|
2000-12-07 |
2004-06-23 |
Hoffmann La Roche |
Hidroxiamidas de acido (1-oxo-1,2,3,4-tetrahidro-naftalen-2-il)-alcanoico, proceso para la manufactura de estos compuestos, composiciones farmaceuticas que contienen dichos compuestos y los usos de los mismos
|
|
US6613753B2
(en)
*
|
2001-02-21 |
2003-09-02 |
Supergen, Inc. |
Restore cancer-suppressing functions to neoplastic cells through DNA hypomethylation
|
|
EP1249246B1
(de)
*
|
2001-04-10 |
2005-09-28 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Verwendung von Histonedeacetylasehemmern zur Behandlung von Papillomaviren assoziierte Krankheiten
|
|
US6905669B2
(en)
*
|
2001-04-24 |
2005-06-14 |
Supergen, Inc. |
Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
|
|
US7241743B2
(en)
*
|
2001-06-15 |
2007-07-10 |
The Trustees Of Columbia University In The City Of New York |
Sir2α-based therapeutic and prophylactic methods
|
|
WO2003032921A2
(en)
*
|
2001-10-16 |
2003-04-24 |
Sloan-Kettering Institute For Cancer Research |
Treatment of neurodegenerative diseases and cancer of the brain
|
|
US20030147813A1
(en)
*
|
2002-02-07 |
2003-08-07 |
John Lyons |
Method for treating chronic myelogenous leukemia
|
|
US6998391B2
(en)
*
|
2002-02-07 |
2006-02-14 |
Supergen.Inc. |
Method for treating diseases associated with abnormal kinase activity
|
|
WO2003070188A2
(en)
*
|
2002-02-15 |
2003-08-28 |
Sloan-Kettering Institute For Cancer Research |
Method of treating trx mediated diseases
|
|
US20030170299A1
(en)
*
|
2002-02-27 |
2003-09-11 |
Lee Robert J. |
Therapeutic methods for acute myeloid leukemia
|
|
US20060276547A1
(en)
*
|
2002-03-04 |
2006-12-07 |
Bacopoulos Nicholas G |
Methods of treating cancer with HDAC inhibitors
|
|
US20070060614A1
(en)
*
|
2002-03-04 |
2007-03-15 |
Bacopoulos Nicholas G |
Methods of treating cancer with hdac inhibitors
|
|
US7456219B2
(en)
*
|
2002-03-04 |
2008-11-25 |
Merck Hdac Research, Llc |
Polymorphs of suberoylanilide hydroxamic acid
|
|
MXPA04008577A
(es)
*
|
2002-03-04 |
2005-07-13 |
Aton Pharma Inc |
Metodos para inducir diferenciacion terminal.
|
|
US7148257B2
(en)
*
|
2002-03-04 |
2006-12-12 |
Merck Hdac Research, Llc |
Methods of treating mesothelioma with suberoylanilide hydroxamic acid
|
|
US20040132825A1
(en)
*
|
2002-03-04 |
2004-07-08 |
Bacopoulos Nicholas G. |
Methods of treating cancer with HDAC inhibitors
|
|
AU2003226408B2
(en)
*
|
2002-04-15 |
2007-06-14 |
Sloan-Kettering Institute For Cancer Research |
Combination therapy for the treatment of cancer
|
|
US6982253B2
(en)
*
|
2002-06-05 |
2006-01-03 |
Supergen, Inc. |
Liquid formulation of decitabine and use of the same
|
|
CA2503150A1
(en)
*
|
2002-10-31 |
2004-05-21 |
Supergen, Inc. |
Pharmaceutical formulations targeting specific regions of the gastrointestinal tract
|
|
CA2529840A1
(en)
*
|
2003-06-27 |
2005-01-06 |
Astellas Pharma Inc. |
Therapeutic agent for soft tissue sarcoma
|
|
US20050037992A1
(en)
*
|
2003-07-22 |
2005-02-17 |
John Lyons |
Composition and method for treating neurological disorders
|
|
PL379887A1
(pl)
*
|
2003-08-26 |
2006-11-27 |
Merck Hdac Research, Llc |
Sposób leczenia raka inhibitorami HDAC
|
|
US20050059682A1
(en)
*
|
2003-09-12 |
2005-03-17 |
Supergen, Inc., A Delaware Corporation |
Compositions and methods for treatment of cancer
|
|
US7875275B2
(en)
*
|
2004-06-16 |
2011-01-25 |
The General Hospital Corporation |
Use of Bridge-1 and activators and inhibitors thereof in the treatment of insulin deficiency and diabetes
|
|
US20060063735A1
(en)
*
|
2004-09-17 |
2006-03-23 |
Supergen, Inc. |
Salts of 5-azacytidine
|
|
US20060069060A1
(en)
*
|
2004-09-27 |
2006-03-30 |
Sanjeev Redkar |
Salts of decitabine
|
|
US7235688B1
(en)
|
2004-11-04 |
2007-06-26 |
University Of Notre Dame Du Lac |
Process for preparing histone deacetylase inhibitors and intermediates thereof
|
|
US20060128653A1
(en)
*
|
2004-12-10 |
2006-06-15 |
Chunlin Tang |
Pharmaceutical formulation of decitabine
|
|
US20060128654A1
(en)
*
|
2004-12-10 |
2006-06-15 |
Chunlin Tang |
Pharmaceutical formulation of cytidine analogs and derivatives
|
|
US7250416B2
(en)
*
|
2005-03-11 |
2007-07-31 |
Supergen, Inc. |
Azacytosine analogs and derivatives
|
|
TWI365068B
(en)
|
2005-05-20 |
2012-06-01 |
Merck Sharp & Dohme |
Formulations of suberoylanilide hydroxamic acid and methods for producing same
|
|
AU2006283677A1
(en)
*
|
2005-08-19 |
2007-03-01 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Topical formulations of histone deacetylase inhibitors and methods of using the same
|
|
US7700567B2
(en)
|
2005-09-29 |
2010-04-20 |
Supergen, Inc. |
Oligonucleotide analogues incorporating 5-aza-cytosine therein
|
|
JP2009514891A
(ja)
*
|
2005-11-04 |
2009-04-09 |
メルク エンド カムパニー インコーポレーテッド |
癌を治療するためのｓａｈａ及びエルロチニブを用いる方法
|
|
US20070105792A1
(en)
*
|
2005-11-04 |
2007-05-10 |
Dimartino Jorge F |
Administration Of DNA Methylation Inhibitors For Treating Epigenetic Diseases
|
|
US20070117776A1
(en)
*
|
2005-11-04 |
2007-05-24 |
John Lyons |
Low Dose Therapy Of DNA Methylation Inhibitors
|
|
AU2006311808A1
(en)
*
|
2005-11-04 |
2007-05-18 |
Merck Sharp & Dohme Corp. |
Methods of using SAHA and bortezomib for treating cancer
|
|
JP2007262058A
(ja)
*
|
2006-03-03 |
2007-10-11 |
Tokyo Univ Of Science |
糸状菌の分化抑制剤
|
|
US20090018142A9
(en)
*
|
2006-05-02 |
2009-01-15 |
Zhengping Zhuang |
Use of phosphatases to treat tumors overexpressing N-CoR
|
|
US20100144885A1
(en)
*
|
2006-09-29 |
2010-06-10 |
The Board Of Trustees Of The University Of Illinois |
Histone acetyl transferase activators and histone deacetylase inhibitors in the treatment of alcoholism
|
|
AU2007317921A1
(en)
*
|
2006-11-03 |
2008-05-15 |
University Of Maryland, Baltimore |
Methods of using SAHA and Bortezomib for treating multiple myeloma
|
|
US7998957B2
(en)
|
2007-02-06 |
2011-08-16 |
Lixte Biotechnology, Inc. |
Oxabicycloheptanes and oxabicylcoheptenes, their preparation and use
|
|
US8043804B2
(en)
*
|
2007-05-23 |
2011-10-25 |
The Trustees Of Columbia University In The City Of New York |
DBC1, a novel native inhibitor of anti-aging protein SIRT1
|
|
CA2718472A1
(en)
*
|
2007-08-03 |
2009-02-12 |
Lixte Biotechnology, Inc. |
Use of phosphatases to treat neuroblastomas and medulloblastomas
|
|
AU2008307541B2
(en)
|
2007-10-01 |
2015-02-12 |
Lixte Biotechnology, Inc. |
HDAC inhibitors
|
|
CA2730428A1
(en)
*
|
2008-08-01 |
2010-02-04 |
Lixte Biotechnology, Inc. |
Methods for regulating cell mitosis by inhibiting serine/threonine phosphatase
|
|
WO2010147612A1
(en)
|
2009-06-18 |
2010-12-23 |
Lixte Biotechnology, Inc. |
Methods of modulating cell regulation by inhibiting p53
|
|
US8227473B2
(en)
*
|
2008-08-01 |
2012-07-24 |
Lixte Biotechnology, Inc. |
Oxabicycloheptanes and oxabicycloheptenes, their preparation and use
|
|
AU2009277086B2
(en)
|
2008-08-01 |
2015-12-10 |
Lixte Biotechnology, Inc. |
Neuroprotective agents for the prevention and treatment of neurodegenerative diseases
|
|
US9381207B2
(en)
|
2011-08-30 |
2016-07-05 |
Astex Pharmaceuticals, Inc. |
Drug formulations
|
|
ES2984267T3
(es)
|
2013-04-09 |
2024-10-29 |
Lixte Biotechnology Inc |
Formulaciones de oxabicicloheptanos y oxabicicloheptenos
|
|
MX2016002307A
(es)
*
|
2013-08-22 |
2016-06-15 |
Vanda Pharmaceuticals Inc |
Tratamiento para el cancer.
|
|
KR20220153684A
(ko)
*
|
2013-08-22 |
2022-11-18 |
반다 파마슈티칼즈, 인코퍼레이티드. |
다발성 골수종 치료
|
|
JP6980534B2
(ja)
|
2015-06-25 |
2021-12-15 |
ザ チルドレンズ メディカル センター コーポレーション |
造血幹細胞の増大、富化、および維持に関する方法および組成物
|
|
CN108024535A
(zh)
|
2015-07-02 |
2018-05-11 |
大塚制药株式会社 |
冻干药物组合物
|
|
US20190119642A1
(en)
|
2016-03-15 |
2019-04-25 |
Children's Medical Center Corporation |
Methods and compositions relating to hematopoietic stem cell expansion
|
|
CN110234647B
(zh)
|
2016-12-08 |
2023-05-23 |
利克斯特生物技术公司 |
用于调节免疫应答的氧杂双环庚烷
|
|
RU2020108580A
(ru)
|
2017-08-03 |
2021-09-03 |
Оцука Фармасьютикал Ко., Лтд. |
Лекарственное соединение и способы его очистки
|