DE3673737D1 - Insulinabkoemmlinge und arzneimittel die diese enthalten. - Google Patents

Insulinabkoemmlinge und arzneimittel die diese enthalten.

Info

Publication number: DE3673737D1
Authority: DE; Germany
Prior art keywords: pct; insuline; bottles; contain; medicinal products
Prior art date: 1985-03-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE8686901826T

Other languages

English (en)

Inventor

Per Balschmidt

Benned Hansen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novo Nordisk AS

Original Assignee

Novo Nordisk AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-15

Filing date

1986-03-14

Publication date

1990-10-04

1986-03-14 Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS

1990-10-04 Application granted granted Critical

1990-10-04 Publication of DE3673737D1 publication Critical patent/DE3673737D1/de

2006-03-15 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

229940126601 medicinal product Drugs 0.000 title 1
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical class N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
125000000539 amino acid group Chemical group 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

DE8686901826T 1985-03-15 1986-03-14 Insulinabkoemmlinge und arzneimittel die diese enthalten. Expired - Lifetime DE3673737D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK119785A DK119785D0 (da)	1985-03-15	1985-03-15	Insulinpraeparat
PCT/DK1986/000022 WO1986005496A1 (en)	1985-03-15	1986-03-14	Novel insulin derivatives and pharmaceutical preparations containing these derivatives

Publications (1)

Publication Number	Publication Date
DE3673737D1 true DE3673737D1 (de)	1990-10-04

Family

ID=8102063

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DE8686901827T Expired - Fee Related DE3687500T2 (de)	1985-03-15	1986-03-14	Insulinabkoemmlinge und arzneimittel die diese enthalten.
DE8686901826T Expired - Lifetime DE3673737D1 (de)	1985-03-15	1986-03-14	Insulinabkoemmlinge und arzneimittel die diese enthalten.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DE8686901827T Expired - Fee Related DE3687500T2 (de)	1985-03-15	1986-03-14	Insulinabkoemmlinge und arzneimittel die diese enthalten.

Country Status (11)

Country	Link
US (1)	US5028586A (de)
EP (2)	EP0216832B1 (de)
JP (2)	JPS62502196A (de)
AT (2)	ATE84546T1 (de)
AU (2)	AU596968B2 (de)
DE (2)	DE3687500T2 (de)
DK (3)	DK119785D0 (de)
FI (2)	FI864559A0 (de)
IL (2)	IL78160A (de)
NO (2)	NO174278C (de)
WO (2)	WO1986005497A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK113585D0 (da) *	1985-03-12	1985-03-12	Novo Industri As	Nye peptider
DK347086D0 (da) *	1986-07-21	1986-07-21	Novo Industri As	Novel peptides
US5157021A (en) *	1985-03-15	1992-10-20	Novo Nordisk A/S	Insulin derivatives and pharmaceutical preparations containing these derivatives
DK437786D0 (da) *	1986-09-12	1986-09-12	Nordisk Gentofte	Insulinprecursorer
IE62879B1 (en) *	1987-02-25	1995-03-08	Novo Nordisk As	Novel insulin derivatives
BR8803345A (pt) *	1988-06-30	1990-02-13	Biobras Bioquimica Do Brasil S	Processo aperfeicoado para producao em larga escala de cristais de insulina humana purificada
BR8803346A (pt) *	1988-06-30	1990-02-13	Biobras Bioquimica Do Brasil S	Processo aperfeicoado para producao em larga escala de cristais de insulina purificada
EP0425482B1 (de) *	1988-07-20	1993-08-18	Novo Nordisk A/S	Menschliche insulinanalage und zubereitungen daraus
US5716927A (en) *	1988-12-23	1998-02-10	Novo Nordisk A/S	Insulin analogs having a modified B-chain
DK134189D0 (da) *	1989-03-20	1989-03-20	Nordisk Gentofte	Insulinforbindelser
WO1992010284A2 (en)	1990-12-07	1992-06-25	Cnc Development, Inc.	Catalytic chemical reactor
DK33591D0 (de) *	1991-02-27	1991-02-27	Novo Nordisk As
AU669110B2 (en) *	1991-05-24	1996-05-30	Amylin Pharmaceuticals, Inc.	Amylin and possibly insulin containing composition for the treatment of anorexia and related states
US5461031A (en) *	1994-06-16	1995-10-24	Eli Lilly And Company	Monomeric insulin analog formulations
AUPO269996A0 (en) *	1996-10-01	1996-10-24	Walter And Eliza Hall Institute Of Medical Research, The	A method of prophylaxis and treatment
US5898067A (en) *	1997-02-07	1999-04-27	Novo Nordisk A/S	Crystallization of proteins
EP1560618A4 (de) *	2002-11-01	2007-07-18	Antares Pharma Inc	Insulinverabreichung mittels jet-injektion
BRPI0506864A (pt)	2004-01-21	2007-05-29	Novo Nordisk As	método para conjugar peptìdeos, peptìdeo conjugado, composto e sais, pró-drogas e solvatos farmaceuticamente aceitáveis destes, composição farmacêutica, uso de um composto, e, método para tratamento de doença
US7833513B2 (en)	2004-12-03	2010-11-16	Rhode Island Hospital	Treatment of Alzheimer's Disease
EP1991575A1 (de) *	2006-02-21	2008-11-19	Novo Nordisk A/S	Einkettige insulinanaloga und pharmazeutische formulierungen daraus
WO2009099763A1 (en) *	2008-01-30	2009-08-13	Indiana University Research And Technology Corporation	Ester-based peptide prodrugs
AR074811A1 (es)	2008-12-19	2011-02-16	Univ Indiana Res & Tech Corp	Profarmaco de peptido de la superfamilia de glucagon basados en amida
WO2010080605A1 (en) *	2008-12-19	2010-07-15	Indiana University Research And Technology Corporation	Dipeptide linked medicinal agents
WO2011163462A2 (en)	2010-06-24	2011-12-29	Indiana University Research And Technology Corporation	Amide-based insulin prodrugs
CN104114183A (zh)	2011-12-20	2014-10-22	印第安纳大学研究及科技有限公司	用于治疗糖尿病的基于ctp的胰岛素类似物
AU2013323669B2 (en)	2012-09-26	2018-03-01	Indiana University Research And Technology Corporation	Insulin analog dimers
WO2014158900A1 (en)	2013-03-14	2014-10-02	Indiana University Research And Technology Corporation	Insulin-incretin conjugates
WO2016049174A1 (en)	2014-09-24	2016-03-31	Indiana University Research And Technology Corporation	Lipidated amide-based insulin prodrugs
ES2822994T3 (es)	2014-09-24	2021-05-05	Univ Indiana Res & Tech Corp	Conjugados de incretina-insulina

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3903068A (en) *	1972-12-26	1975-09-02	Us Health Education & Welfare	Facile synthesis of human insulin by modification of porcine insulin
JPS55138393A (en) *	1979-04-13	1980-10-29	Shionogi & Co Ltd	Semisynthesis of insulin
DK146482C (da) *	1979-04-13	1986-10-06	Shionogi & Co	Fremgangsmaade til fremstilling af et b30-threonin-insulin
JPS55138391A (en) *	1979-04-13	1980-10-29	Shionogi & Co Ltd	New synthetic method of peptide derivative
DK147437A (en) *	1980-02-11	1900-01-01		Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4421685A (en) *	1980-03-27	1983-12-20	Eli Lilly And Company	Process for producing an insulin
DK319780A (da) *	1980-07-24	1982-01-25	Forenede Bryggerier As	Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
IE52768B1 (en) *	1981-04-06	1988-02-17	Boots Co Ltd	1-arylcyclobutylalkylamine compounds useful as therapeutic agents
DE3327709A1 (de) *	1983-07-29	1985-02-07	Hoechst Ag, 6230 Frankfurt	Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK113585D0 (da) *	1985-03-12	1985-03-12	Novo Industri As	Nye peptider

1985
- 1985-03-15 DK DK119785A patent/DK119785D0/da not_active Application Discontinuation
1986
- 1986-03-14 AU AU56227/86A patent/AU596968B2/en not_active Ceased
- 1986-03-14 IL IL78160A patent/IL78160A/xx not_active IP Right Cessation
- 1986-03-14 EP EP86901826A patent/EP0216832B1/de not_active Expired - Lifetime
- 1986-03-14 AT AT86901827T patent/ATE84546T1/de not_active IP Right Cessation
- 1986-03-14 AU AU56226/86A patent/AU5622686A/en not_active Abandoned
- 1986-03-14 IL IL78161A patent/IL78161A0/xx unknown
- 1986-03-14 DE DE8686901827T patent/DE3687500T2/de not_active Expired - Fee Related
- 1986-03-14 JP JP61501710A patent/JPS62502196A/ja active Pending
- 1986-03-14 AT AT86901826T patent/ATE56022T1/de not_active IP Right Cessation
- 1986-03-14 EP EP86901827A patent/EP0216833B1/de not_active Expired - Lifetime
- 1986-03-14 US US07/002,672 patent/US5028586A/en not_active Expired - Fee Related
- 1986-03-14 WO PCT/DK1986/000023 patent/WO1986005497A1/en active IP Right Grant
- 1986-03-14 WO PCT/DK1986/000022 patent/WO1986005496A1/en active IP Right Grant
- 1986-03-14 DE DE8686901826T patent/DE3673737D1/de not_active Expired - Lifetime
- 1986-03-14 JP JP61501709A patent/JPS62502538A/ja active Pending
- 1986-11-10 FI FI864559A patent/FI864559A0/fi not_active IP Right Cessation
- 1986-11-10 FI FI864560A patent/FI93460C/fi not_active IP Right Cessation
- 1986-11-14 NO NO864556A patent/NO174278C/no unknown
- 1986-11-14 NO NO864555A patent/NO864555D0/no unknown
- 1986-11-14 DK DK545786A patent/DK159856C/da not_active IP Right Cessation
- 1986-11-14 DK DK545686A patent/DK545686D0/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
FI93460C (fi)	1995-04-10
FI864559A (fi)	1986-11-10
FI864560A (fi)	1986-11-10
NO864556L (no)	1986-11-14
DK545786D0 (da)	1986-11-14
EP0216832B1 (de)	1990-08-29
EP0216832A1 (de)	1987-04-08
DK545686A (da)	1986-11-14
ATE84546T1 (de)	1993-01-15
JPS62502196A (ja)	1987-08-27
DK119785D0 (da)	1985-03-15
AU5622686A (en)	1986-10-13
NO174278B (no)	1994-01-03
JPS62502538A (ja)	1987-10-01
WO1986005497A1 (en)	1986-09-25
EP0216833B1 (de)	1993-01-13
WO1986005496A1 (en)	1986-09-25
AU5622786A (en)	1986-10-13
FI864560A0 (fi)	1986-11-10
DK159856C (da)	1991-05-06
DE3687500D1 (de)	1993-02-25
FI864559A0 (fi)	1986-11-10
ATE56022T1 (de)	1990-09-15
IL78160A (en)	1991-06-10
DK545686D0 (da)	1986-11-14
IL78161A0 (en)	1986-07-31
US5028586A (en)	1991-07-02
IL78160A0 (en)	1986-07-31
EP0216833A1 (de)	1987-04-08
AU596968B2 (en)	1990-05-24
NO174278C (no)	1994-04-13
NO864556D0 (no)	1986-11-14
DK545786A (da)	1986-11-14
DK159856B (da)	1990-12-17
NO864555L (no)	1986-11-14
NO864555D0 (no)	1986-11-14
DE3687500T2 (de)	1993-07-01
FI93460B (fi)	1994-12-30

Publication	Publication Date	Title
DE3673737D1 (de)	1990-10-04	Insulinabkoemmlinge und arzneimittel die diese enthalten.
DE3679908D1 (de)	1991-07-25	Hexadecylphosphocolin enthaltende arzneimittel mit antitumorwirkung.
AT388913B (de)	1989-09-25	Neue n-(2'-aminophenyl)-benzamid-derivate und arzneimittel, die diese enthalten
ATE151278T1 (de)	1997-04-15	Pharmazeutische und dermokosmetische mittel enthaltend pferdecolostrum
DE69222950D1 (de)	1997-12-04	Darmlösliche oral verabreichbare arzneimittel welche säurelabile verbindungen enthalten
ZA88754B (en)	1988-08-04	Substituted 3,4-dihydro-2h-benzopyrans,processes for their preparation,their use and pharmaceutical products based on these compounds
ATE67210T1 (de)	1991-09-15	Androstane-17-beta-carbonsaeureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.
EP0515995A3 (en)	1993-07-21	N-(5-thioxo-l-prolyl)-l-cysteine, derivatives thereof, processes for the preparation thereof and pharmaceutical compositions containing them
NZ231320A (en)	1992-11-25	Aqueous oral preparations of diclofenac
DE3662520D1 (en)	1989-04-27	Cis-1,3,5-triamino 2,4,6-cyclohexanetriol derivatives, their use, process for their preparation and pharmaceutical preparations containing them
DE3874390D1 (de)	1992-10-15	Carboxystyrol-derivate und arzneimittel, die sie als wirkstoff enthalten.
DE3678541D1 (de)	1991-05-08	N-vinylimidazole und -triazole und diese enthaltende arzneimittel.
ATE5073T1 (de)	1983-11-15	5-amino-tetrazol-derivate von retinsaeuren, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
DK0588177T3 (da)	2000-05-08	Interferon-alpha/beta-bindende protein, fremstilling heraf samt farmaceutiske præparater indeholdende proteinet
DK578589A (da)	1990-05-20	Farmaceutisk praeparat indeholdende labdanterpenoidderivater og pyrimido(6,1-a)isoquinolin-4-onderivater, dets fremstilling og anvendelse
ATE57935T1 (de)	1990-11-15	16,17-acetalsubstituierte pregnan-21-saeure, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate.
DE3671630D1 (de)	1990-07-05	Glycero-3(2)-phospho-l-serinderivate und diese enthaltende pharmazeutischen praeparate.
GR3000330T3 (en)	1991-06-07	N,n-bis-(4-fluorophenyl) carbamoyl acetohydroxamic acid and pharmaceutical composition containing it
ZA885337B (en)	1989-03-29	Leukotriene antagonists,a process for the preparation thereof,and the use thereof for the treatment of diseases
IT1264637B1 (it)	1996-10-04	Composizioni farmaceutiche e/o dermocosmetologiche e cosmetiche contenenti colostro equino
ATE44128T1 (de)	1989-07-15	(1-phenylmethyl-5-hydroxy-1h-indazol-3-yl)oxyessigs\|ure und deren salze zur verwendung als heilmittel und diese enthaltende pharmazeutische zusammensetzungen.

Legal Events

Date	Code	Title	Description
1991-09-26	8364	No opposition during term of opposition
1992-04-09	8339	Ceased/non-payment of the annual fee