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DE3582382D1 - Xanthon-derivate und verfahren zu ihrer herstellung. - Google Patents

Xanthon-derivate und verfahren zu ihrer herstellung.

Info

Publication number
DE3582382D1
DE3582382D1 DE8585111907T DE3582382T DE3582382D1 DE 3582382 D1 DE3582382 D1 DE 3582382D1 DE 8585111907 T DE8585111907 T DE 8585111907T DE 3582382 T DE3582382 T DE 3582382T DE 3582382 D1 DE3582382 D1 DE 3582382D1
Authority
DE
Germany
Prior art keywords
hydrogen atom
group
carboxyl group
derivatives
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585111907T
Other languages
English (en)
Inventor
Hiroshi Koga
Takashi Mori
Takashi Dan
Michitaka Akima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59196796A external-priority patent/JPS6176476A/ja
Priority claimed from JP59204351A external-priority patent/JPS6183187A/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3582382D1 publication Critical patent/DE3582382D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86—Oxygen atoms, e.g. xanthones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyrane Compounds (AREA)
DE8585111907T 1984-09-21 1985-09-20 Xanthon-derivate und verfahren zu ihrer herstellung. Expired - Fee Related DE3582382D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59196796A JPS6176476A (ja) 1984-09-21 1984-09-21 キサントン誘導体
JP59204351A JPS6183187A (ja) 1984-09-28 1984-09-28 フロキサントン誘導体

Publications (1)

Publication Number Publication Date
DE3582382D1 true DE3582382D1 (de) 1991-05-08

Family

ID=26509990

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585111907T Expired - Fee Related DE3582382D1 (de) 1984-09-21 1985-09-20 Xanthon-derivate und verfahren zu ihrer herstellung.

Country Status (6)

Country Link
US (2) US4661607A (de)
EP (1) EP0175376B1 (de)
AT (1) ATE62238T1 (de)
CA (1) CA1234126A (de)
DE (1) DE3582382D1 (de)
HU (2) HU200174B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996230A (en) * 1990-02-16 1991-02-26 Eli Lilly And Company Leukotriene antagonists
IT1261662B (it) * 1992-09-07 1996-05-28 Inverni Della Beffa Spa Derivati xantonici, loro preparazione ed attivita'
US5495005A (en) * 1993-08-26 1996-02-27 National Science Council Synthesis and pharmacological activity of a series of novel xanthone derivatives
US5977077A (en) * 1995-08-28 1999-11-02 Interlab Corporation Xanthone analogs for the treatment of infectious diseases
US6613797B2 (en) 1999-12-02 2003-09-02 Interlab, Inc. Xanthone analogs for treating infectious diseases and complexation of heme and porphyrins
CA2489768A1 (en) * 2001-05-18 2002-11-28 Board Of Regents, The University Of Texas System Methods for preparation and use of psorospermin analogs
CA2513021A1 (en) * 2002-08-30 2004-03-11 Cylene Pharmaceuticals, Inc. Process to prepare psorospermin
US8853261B2 (en) * 2008-01-21 2014-10-07 Laila Nutraceuticals Nutraceutical composition from Garcinia mangostana
US8673920B2 (en) * 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2632465B1 (de) 2010-10-27 2015-12-30 Merck Sharp & Dohme Corp. Inhibitoren des renalen kaliumkanals der äusseren medulla
US9056859B2 (en) 2010-10-29 2015-06-16 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013028474A1 (en) 2011-08-19 2013-02-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
TW201317213A (zh) 2011-09-16 2013-05-01 Merck Sharp & Dohme 腎外髓質鉀通道抑制劑
US8999991B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8999990B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9108947B2 (en) 2011-10-31 2015-08-18 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
WO2013066718A2 (en) 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9139585B2 (en) 2011-10-31 2015-09-22 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
EP2790511B1 (de) 2011-12-16 2016-09-14 Merck Sharp & Dohme Corp. Inhibitoren des renalen kaliumkanals der äusseren medulla
AR092031A1 (es) 2012-07-26 2015-03-18 Merck Sharp & Dohme Inhibidores del canal de potasio medular externo renal
US9777002B2 (en) 2012-11-29 2017-10-03 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2014099633A2 (en) 2012-12-19 2014-06-26 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9604998B2 (en) 2013-02-18 2017-03-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9765074B2 (en) 2013-03-15 2017-09-19 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2015017305A1 (en) 2013-07-31 2015-02-05 Merck Sharp & Dohme Corp Inhibitors of the renal outer medullary potassium channel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE923132C (de) * 1952-06-29 1955-02-03 Mabeg Maschb G M B H Vorrichtung zum Vereinzeln und zum Zufuehren von Bogen aus Papier usw. an Druck-, Lackier- und Falzmaschinen
DE1172271B (de) * 1960-01-20 1964-06-18 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Xanthon-3-oxyessigsaeurealkylestern
FR1417961A (fr) * 1961-01-19 1965-11-19 Cassella Farbwerke Mainkur Ag Procédé de préparation de dérivés d'hydroxy-xanthones
BE757001A (fr) * 1969-10-10 1971-03-16 Cerpha Derives heterocycliques d'acides phenoxy acetique et leur preparation
IT1166191B (it) * 1979-12-12 1987-04-29 Medea Res Srl Acidi 2 xantonossi 2 metilpropionici loro esteri e loro sali caratterizzati da attivita ipolipemizzante

Also Published As

Publication number Publication date
HU201076B (en) 1990-09-28
HUT41760A (en) 1987-05-28
EP0175376A2 (de) 1986-03-26
CA1234126A (en) 1988-03-15
ATE62238T1 (de) 1991-04-15
EP0175376B1 (de) 1991-04-03
US4661607A (en) 1987-04-28
HU200174B (en) 1990-04-28
HU896028D0 (en) 1990-02-28
US4816479A (en) 1989-03-28
EP0175376A3 (en) 1988-07-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee