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DE3574730D1 - Monoklonaler antikoerper gegen ein humanes tumor-karzinom-assoziiertes antigen. - Google Patents

Monoklonaler antikoerper gegen ein humanes tumor-karzinom-assoziiertes antigen.

Info

Publication number
DE3574730D1
DE3574730D1 DE8585904190T DE3574730T DE3574730D1 DE 3574730 D1 DE3574730 D1 DE 3574730D1 DE 8585904190 T DE8585904190 T DE 8585904190T DE 3574730 T DE3574730 T DE 3574730T DE 3574730 D1 DE3574730 D1 DE 3574730D1
Authority
DE
Germany
Prior art keywords
antique
monoclonal antibody
antibody against
human tumor
carcinoma associated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585904190T
Other languages
English (en)
Inventor
H Kortright
E Hofheinz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coulter Corp
Original Assignee
Coulter Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Corp filed Critical Coulter Corp
Application granted granted Critical
Publication of DE3574730D1 publication Critical patent/DE3574730D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE8585904190T 1984-11-09 1985-08-08 Monoklonaler antikoerper gegen ein humanes tumor-karzinom-assoziiertes antigen. Expired - Fee Related DE3574730D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67032884A 1984-11-09 1984-11-09
US06/702,059 US4708930A (en) 1984-11-09 1985-02-15 Monoclonal antibody to a human carcinoma tumor associated antigen
PCT/US1985/001511 WO1986002945A1 (en) 1984-11-09 1985-08-08 Monoclonal antibody to a human carcinoma tumor associated antigen

Publications (1)

Publication Number Publication Date
DE3574730D1 true DE3574730D1 (de) 1990-01-18

Family

ID=27100290

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585904190T Expired - Fee Related DE3574730D1 (de) 1984-11-09 1985-08-08 Monoklonaler antikoerper gegen ein humanes tumor-karzinom-assoziiertes antigen.

Country Status (14)

Country Link
US (1) US4708930A (de)
EP (1) EP0201509B1 (de)
KR (1) KR900003923B1 (de)
CN (1) CN1009055B (de)
AU (1) AU593467B2 (de)
BR (1) BR8507031A (de)
CA (1) CA1243969A (de)
DE (1) DE3574730D1 (de)
DK (1) DK323486D0 (de)
ES (1) ES8705975A1 (de)
HU (1) HUT40692A (de)
IL (1) IL76142A (de)
NO (1) NO862641D0 (de)
WO (1) WO1986002945A1 (de)

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US4926869A (en) * 1986-01-16 1990-05-22 The General Hospital Corporation Method for the diagnosis and treatment of inflammation
EP0232871A3 (de) * 1986-02-07 1989-03-15 Yoshitomi Pharmaceutical Industries, Ltd. Menschlicher monoklonaler Antikörper, Hybridoma zu seiner Herstellung und seine Verwendung
US4863851A (en) * 1986-10-20 1989-09-05 The Upjohn Company Monoclonal antibody to prostate secretory protein
DE3713301A1 (de) * 1987-04-18 1988-11-03 Becker Helmut Dipl Wirtsch Ing Verfahren zur durchflussmengenmessung und thermischer durchflussgeber hierfuer
CA1340927C (en) * 1987-10-09 2000-03-14 Peter S. Linsley Method for increasing the sensitivity of assays for target ligand
US5204450A (en) * 1988-03-04 1993-04-20 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses
US4914021A (en) * 1988-03-04 1990-04-03 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses
US5241052A (en) * 1988-03-04 1993-08-31 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses
US5171666A (en) * 1988-04-22 1992-12-15 Eli Lilly And Company Monoclonal antibodies reactive with a cell-surface gylcoprotein expressed on human carcinomas
US5242824A (en) * 1988-12-22 1993-09-07 Oncogen Monoclonal antibody to human carcinomas
US5134075A (en) * 1989-02-17 1992-07-28 Oncogen Limited Partnership Monoclonal antibody to novel antigen associated with human tumors
FR2645877B1 (fr) * 1989-04-12 1991-07-05 Pasteur Institut Molecules comportant au moins une sequence peptidique porteuse d'un, ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum au niveau du stade sporozoite et dans les hepatocytes
US5171665A (en) * 1989-04-17 1992-12-15 Oncogen Monoclonal antibody to novel antigen associated with human tumors
US5980896A (en) * 1989-06-30 1999-11-09 Bristol-Myers Squibb Company Antibodies reactive with human carcinomas
IL94872A (en) * 1989-06-30 1995-03-30 Oncogen Monoclonal or chimeric antibodies that react with human carcinoma, recombinant proteins that contain their anti-binding site, pharmaceutical preparations and kits that contain the
US6020145A (en) * 1989-06-30 2000-02-01 Bristol-Myers Squibb Company Methods for determining the presence of carcinoma using the antigen binding region of monoclonal antibody BR96
EP0460607A3 (en) * 1990-06-05 1992-04-01 Bristol-Myers Squibb Company Novel monoclonal antibody to novel antigen associated with human tumors
AU5615594A (en) * 1992-11-13 1994-06-08 Cancer Research Fund Of Contra Costa Polypeptides with specificity for neoplasias, kit, and diagnostic, vaccination, and therapeutic methods
US5792852A (en) * 1992-11-16 1998-08-11 Cancer Research Fund Of Contra Costa Polynucleotides encoding modified antibodies with human milk fat globule specificity
DE69332930T2 (de) * 1992-11-16 2004-02-26 Cancer Research Fund Of Contra Costa, Walnut Creek Peptide mit breiter neoplastischer spezifizität
US6281335B1 (en) 1993-10-08 2001-08-28 Coulter Corporation Hybridoma and anti-KC-4 humanized monoclonal antibody
US5804187A (en) 1992-11-16 1998-09-08 Cancer Research Fund Of Contra Costa Modified antibodies with human milk fat globule specificity
JP4122050B2 (ja) * 1993-02-05 2008-07-23 イージェニックス，インク． ヒト癌腫抗原（ｈｃａ）、ｈｃａ抗体、ｈｃａ免疫アッセイ法、画像化の方法及び治療
US5792456A (en) * 1994-08-04 1998-08-11 Bristol-Myers Squibb Company Mutant BR96 antibodies reactive with human carcinomas
US5728821A (en) * 1994-08-04 1998-03-17 Bristol-Myers Squibb Company Mutant BR96 antibodies reactive with human carcinomas
US6309636B1 (en) * 1995-09-14 2001-10-30 Cancer Research Institute Of Contra Costa Recombinant peptides derived from the Mc3 anti-BA46 antibody, methods of use thereof, and methods of humanizing antibody peptides
US20020192211A1 (en) * 1998-03-17 2002-12-19 Hudziak Robert M. Method of treating tumor cells by inhibiting growth factor receptor function
US20020147143A1 (en) 1998-03-18 2002-10-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US20030235557A1 (en) 1998-09-30 2003-12-25 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US6471968B1 (en) 2000-05-12 2002-10-29 Regents Of The University Of Michigan Multifunctional nanodevice platform
AR029540A1 (es) 2000-06-28 2003-07-02 Corixa Corp COMPOSICIONES Y METODOS PARA EL DIAGNoSTICO Y LA TERAPIA DE CA NCER DE PULMoN
ZA200305980B (en) 2001-02-12 2007-01-31 Res Dev Foundation Modified proteins, designer toxins, and methods of making thereof
WO2003007889A2 (en) 2001-07-17 2003-01-30 Research Development Foundation Therapeutic agents comprising pro-apoptotic proteins
CA2860702C (en) 2001-12-17 2019-02-26 Corixa Corporation Compositions and methods for the therapy and diagnosis of inflammatory bowel disease
EP1668026A1 (de) * 2003-09-05 2006-06-14 The Scripps Research Institute Nachweis von cholesterin-ozonierungsprodukten
WO2005023830A2 (en) * 2003-09-05 2005-03-17 The Scripps Research Institute Ozonation products of cholesterol for the treatment and prevention of atherosclerosis and/or cardiovascular diseases
JP2008505853A (ja) * 2004-04-13 2008-02-28 クインテセンス バイオサイエンシーズ インコーポレーティッド 細胞傷害性薬剤としての非天然のリボヌクレアーゼ複合体
CA2578205A1 (en) * 2004-08-25 2006-03-30 The Regents Of The University Of Michigan Partially acetylated dendrimers and related methods of use
US20070041934A1 (en) * 2005-08-12 2007-02-22 Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
BRPI0619582A2 (pt) * 2005-12-08 2012-12-11 Medarex Inc anticorpo monoclonal humano isolado ou uma porção de ligação de antigéno do mesmo, composição, imonuconjugado, molécula de ácido nucleico isolada, vetor de expressão, célula hospedeira, e, métodos para preparar um anticorpo anti-ptk7 e para tratar ou prevenir uma doença
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US7501179B2 (en) 2005-12-21 2009-03-10 Boston Scientific Scimed, Inc. Block copolymer particles
EP2044097A4 (de) 2006-06-23 2010-10-06 Quintessence Biosciences Inc Modifizierte ribonukleasen
JP2009543868A (ja) 2006-07-17 2009-12-10 クインテセンス バイオサイエンシーズ インコーポレーティッド 癌治療に関する方法および組成物
WO2009009203A2 (en) * 2007-04-19 2009-01-15 The Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US7890055B1 (en) * 2007-07-09 2011-02-15 Everlokt Corporation Touch field compound field detector personal ID
WO2009026540A1 (en) 2007-08-22 2009-02-26 Colorado School Of Mines Lanthanide nanoparticle conjugates and uses thereof
US8697062B2 (en) * 2007-10-08 2014-04-15 Quintessence Biosciences, Inc. Compositions and methods for ribonuclease-based therapeutics
US8252834B2 (en) 2008-03-12 2012-08-28 The Regents Of The University Of Michigan Dendrimer conjugates
WO2010096464A1 (en) 2009-02-18 2010-08-26 Boyes Stephen G Gold/lanthanide nanoparticle conjugates and uses thereof
US8889635B2 (en) 2008-09-30 2014-11-18 The Regents Of The University Of Michigan Dendrimer conjugates
EP2334695B1 (de) 2008-10-01 2015-12-23 Quintessence Biosciences, Inc. Therapeutische ribonukleasen
WO2010042823A1 (en) 2008-10-09 2010-04-15 Northeastern Universtiy Multifunctional self-assembling polymeric nanosystems
WO2010054321A2 (en) 2008-11-07 2010-05-14 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
US8945508B2 (en) 2009-10-13 2015-02-03 The Regents Of The University Of Michigan Dendrimer compositions and methods of synthesis
WO2011059586A2 (en) 2009-10-30 2011-05-19 The Regents Of The University Of Michigan Multifunctional small molecules
US20110201076A1 (en) 2010-01-22 2011-08-18 Colorado School Of Mines Harvesting micro algae
CN103608030A (zh) 2011-06-21 2014-02-26 昂科发克特公司 用于治疗和诊断癌症的组合物和方法
US9402911B2 (en) 2011-12-08 2016-08-02 The Regents Of The University Of Michigan Multifunctional small molecules
EP2964670B1 (de) * 2013-03-08 2020-12-09 Regeneron Pharmaceuticals, Inc. Menschliche antikörper gegen serumresistenzassoziiertes protein aus trypanosoma brucei rhodesiense

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US4472371A (en) * 1979-10-29 1984-09-18 Summa Medical Corporation Radiolabeled antibody to anti-tumor associated antigen and process
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US4348376A (en) * 1980-03-03 1982-09-07 Goldenberg Milton David Tumor localization and therapy with labeled anti-CEA antibody
US4331647A (en) * 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
US4361544A (en) * 1980-03-03 1982-11-30 Goldenberg Milton David Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers
US4359457A (en) * 1980-09-30 1982-11-16 Neville Jr David M Anti Thy 1.2 monoclonal antibody-ricin hybrid utilized as a tumor suppressant
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US4522918A (en) * 1981-12-15 1985-06-11 Jeffery Schlom Process for producing monoclonal antibodies reactive with human breast cancer
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US4507391A (en) * 1982-04-02 1985-03-26 Sloan-Kettering Institute For Cancer Research Method for detecting the presence of GD3 ganglioside
US4454106A (en) * 1982-06-07 1984-06-12 Gansow Otto A Use of metal chelate conjugated monoclonal antibodies
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Also Published As

Publication number Publication date
IL76142A0 (en) 1985-12-31
ES8705975A1 (es) 1987-05-16
AU4725485A (en) 1986-06-03
NO862641L (no) 1986-06-30
DK323486A (da) 1986-07-07
KR900003923B1 (ko) 1990-06-04
CN1009055B (zh) 1990-08-08
NO862641D0 (no) 1986-06-30
ES546325A0 (es) 1987-05-16
DK323486D0 (da) 1986-07-07
HUT40692A (en) 1987-01-28
KR880700061A (ko) 1988-02-15
AU593467B2 (en) 1990-02-08
CN85107599A (zh) 1986-07-09
WO1986002945A1 (en) 1986-05-22
IL76142A (en) 1990-04-29
US4708930A (en) 1987-11-24
EP0201509B1 (de) 1989-12-13
BR8507031A (pt) 1987-01-06
CA1243969A (en) 1988-11-01
EP0201509A1 (de) 1986-11-20

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee