[go: up one dir, main page]

DE3382240D1 - Durch amino-radikale substituierte heterozyklische derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents

Durch amino-radikale substituierte heterozyklische derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Info

Publication number
DE3382240D1
DE3382240D1 DE8383402549T DE3382240T DE3382240D1 DE 3382240 D1 DE3382240 D1 DE 3382240D1 DE 8383402549 T DE8383402549 T DE 8383402549T DE 3382240 T DE3382240 T DE 3382240T DE 3382240 D1 DE3382240 D1 DE 3382240D1
Authority
DE
Germany
Prior art keywords
production
pharmaceutical compositions
compositions containing
substituted heterocyclic
radical substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8383402549T
Other languages
English (en)
Inventor
Gerard Moinet
Michel Schaefer
Pierre Bessin
Jacqueline Bonnet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Albert Rolland SA
Original Assignee
Laboratoires Albert Rolland SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Albert Rolland SA filed Critical Laboratoires Albert Rolland SA
Application granted granted Critical
Publication of DE3382240D1 publication Critical patent/DE3382240D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/17—Unsaturated ethers containing halogen
    • C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/46—Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/52—Nitrogen atoms not forming part of a nitro radical with hetero atoms directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE8383402549T 1982-12-28 1983-12-28 Durch amino-radikale substituierte heterozyklische derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. Expired - Fee Related DE3382240D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH759182 1982-12-28

Publications (1)

Publication Number Publication Date
DE3382240D1 true DE3382240D1 (de) 1991-05-08

Family

ID=4327534

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383402549T Expired - Fee Related DE3382240D1 (de) 1982-12-28 1983-12-28 Durch amino-radikale substituierte heterozyklische derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Country Status (17)

Country Link
US (2) US4647557A (de)
EP (1) EP0117961B1 (de)
JP (1) JPS59130874A (de)
KR (1) KR910000044B1 (de)
AT (1) ATE62231T1 (de)
AU (1) AU574058B2 (de)
CA (1) CA1220479A (de)
DD (1) DD219766A5 (de)
DE (1) DE3382240D1 (de)
DK (1) DK599483A (de)
ES (3) ES8608493A1 (de)
IL (1) IL70600A0 (de)
IN (1) IN163582B (de)
MA (1) MA19988A1 (de)
PH (1) PH22575A (de)
PT (1) PT77902B (de)
ZA (1) ZA839656B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK302185A (da) * 1984-07-05 1986-01-06 Rolland Sa A 2-amino-oxazoliner samt fremgangsmaade til deres fremstilling
US5616591A (en) * 1992-03-27 1997-04-01 E.R. Squibb & Sons, Inc. Indole- and benzimidazole-substituted quinoline derivatives
JP2008303145A (ja) * 2005-09-22 2008-12-18 Takeda Chem Ind Ltd Ｇｒｋ阻害剤からなる強心薬
EP2173719A1 (de) * 2007-07-03 2010-04-14 F. Hoffmann-Roche AG 4-imidazoline und ihre verwendung als antidepressiva
WO2012007426A1 (en) 2010-07-13 2012-01-19 Basf Se Azoline substituted isoxazoline benzamide compounds for combating animal pests
US10836706B2 (en) * 2016-02-24 2020-11-17 Rutgers, The State University Of New Jersey Bacterial efflux pump inhibitors

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2331995A (en) * 1942-04-17 1943-10-19 Goodrich Co B F Aldehyde-aminothiazoline reaction product
US2636037A (en) * 1947-10-10 1953-04-21 Sharp & Dohme Inc 2-amino-4-piperidinoethyl-thiazole
US3147270A (en) * 1961-11-03 1964-09-01 Warner Lambert Pharmaceutical Substituted 2-imidazolines
DE1595923A1 (de) * 1965-02-20 1969-11-27 Merck Ag E 1-Aralkyl-4-(thiazolyl-2)-piperazine und Verfahren zu ihrer Herstellung
BE787683A (fr) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-phenylimino-imidazolidines, leurs sels d'addition avec des acides et procedes pour les fabriquer
US3926982A (en) * 1974-07-03 1975-12-16 Squibb & Sons Inc Substituted benzimidazolinethiones
US3927014A (en) * 1974-07-29 1975-12-16 Squibb & Sons Inc Substituted mercapto benzimidazoles
CH593806A5 (de) * 1974-11-14 1977-12-15 Ciba Geigy Ag
DE2525725C3 (de) * 1975-06-10 1979-09-13 C.H. Boehringer Sohn, 6507 Ingelheim Basisch substituierte 2-AIkylamino-4-phenyl-imidazoline, deren Säureadditionssalze, Verfahren zu ihrer Herstellung und deren Verwendung
US4120690A (en) * 1976-11-22 1978-10-17 Gulf Oil Corporation 2-Acylaminothiazol-4-ylacetamides as post-emergent selective herbicides
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
IE47044B1 (en) * 1977-04-20 1983-12-14 Ici Ltd Guanidine derivatives
NL7711390A (nl) * 1977-10-18 1979-04-20 Philips Nv Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen.
US4247705A (en) * 1979-02-06 1981-01-27 A. H. Robins Company, Inc. 4-Substituted 2-iminoimidazolidine compounds
EP0069154B1 (de) * 1981-01-13 1986-10-15 Mitsui Toatsu Kagaku Kabushiki Kaisha Neue thiazolverbindungen, verfahren zu deren herstellung und diese enthaltendes arzneimittel
DE3227329A1 (de) * 1982-07-22 1984-01-26 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 2-n,n-disubstituierten aminothiazolen

Also Published As

Publication number Publication date
PT77902A (fr) 1984-01-01
ES528450A0 (es) 1986-07-16
EP0117961B1 (de) 1991-04-03
AU574058B2 (en) 1988-06-30
IN163582B (de) 1988-10-15
ES8608493A1 (es) 1986-07-16
ZA839656B (en) 1984-08-29
ATE62231T1 (de) 1991-04-15
PH22575A (en) 1988-10-17
DK599483A (da) 1984-06-29
ES554071A0 (es) 1987-10-16
DK599483D0 (da) 1983-12-27
IL70600A0 (en) 1984-04-30
ES8802034A1 (es) 1988-03-16
US4826861A (en) 1989-05-02
AU2304984A (en) 1984-08-09
EP0117961A1 (de) 1984-09-12
KR840006974A (ko) 1984-12-04
PT77902B (fr) 1986-05-08
ES8800171A1 (es) 1987-10-16
US4647557A (en) 1987-03-03
ES554070A0 (es) 1988-03-16
DD219766A5 (de) 1985-03-13
CA1220479A (fr) 1987-04-14
MA19988A1 (fr) 1984-07-01
JPS59130874A (ja) 1984-07-27
KR910000044B1 (ko) 1991-01-19

Similar Documents

Publication Publication Date Title
FR2680507B1 (fr) Nouvelles naphtylethylurees et naphtylethylthiourees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
ATE7697T1 (de) Substituierte pyrazinyl-1,2,4-oxadiazol-5-one, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.
IL113894A0 (en) Oxalylamino-benzofuran- and benzothienyl-derivatives process for their preparation pharmaceutical compositions containing them and their use
DE68914488D1 (de) 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide, Verfahren und Zwischenprodukte zu deren Herstellung.
DE3270015D1 (en) 3-(1-substituted-4-piperidyl)-1,2-benzisoxazoles, a process for the preparation thereof, a pharmaceutical composition comprising the same, and their use as medicaments
ATE16591T1 (de) Neue quartaere 6,11-dihydro-dibenzo-(b,e)-thiepin11-n-alkyl-norscopinether und verfahren zu deren herstellung.
ATE51620T1 (de) 3-(4-piperidinyl)-1,2-benzisothiazole und deren derivate, verfahren zu ihrer herstellung und verwendung als arzneimittel.
FI945975A0 (fi) Haarautuneella aminoryhmällä substituoituja tiatsoleja, menetelmiä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia
DK0450420T3 (da) Heterocyclisk substituerede dihydropyridiner, fremgangsmåde til deres fremstilling og deres anvendelse i lægemidler
DE3382240D1 (de) Durch amino-radikale substituierte heterozyklische derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
ATE40369T1 (de) Purinderivate.
DE59010302D1 (de) R-(-)-1-(5-Hydroxyhexyl)-3-methyl-7-propylxanthin, Verfahren zu dessen Herstellung und diese Verbindung enthaltende Arzneimittel
DE3371515D1 (en) Cycloalkyl derivatives of benzisoselenazolones, process for their preparation and pharmaceutical compositions containing them
ATE81499T1 (de) 2-acyloxypropylamin-derivate, verfahren zur herstellung und diese enthaltende arzneimittel.
DE3162277D1 (en) N-(4-phenyl-2-thiazolyl)-oxamidic-acid-2-ethoxyethylester, process for its preparation and pharmaceutical compositions containing this compound
PT81702B (de) N-substituierte aziridin-2-carbonsauerederivate verfahren zu deren herstellung sowie diese substanzen enthaltende arzneimittel
ATE52260T1 (de) Aminomethyl-6-furo(3,4-c>pyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
ATE10934T1 (de) Peptid, verfahren zu dessen herstellung und dessen verwendung.
SE8300865D0 (sv) Mjoldrygealkaloider, forfarande for framstellning derav och dessa foreningar innehallande farmaceutiska kompositioner
ATA236490A (de) Neue selenophenderivate, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
ATE1464T1 (de) N-amino-3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung, sie enthaltende arzneimittel, verfahren zu deren herstellung und die genannten verbindungen enthaltende tierfuttermittel.
ZA80620B (en) New dextrorotatory basic derivative of 9,10-ethanoanthracene,process for the manufacture thereof,pharmaceutical compositions containing this compound and their use

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee