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DE3363270D1 - Solubilized platinum(ii) complexes - Google Patents

Solubilized platinum(ii) complexes

Info

Publication number
DE3363270D1
DE3363270D1 DE8383303687T DE3363270T DE3363270D1 DE 3363270 D1 DE3363270 D1 DE 3363270D1 DE 8383303687 T DE8383303687 T DE 8383303687T DE 3363270 T DE3363270 T DE 3363270T DE 3363270 D1 DE3363270 D1 DE 3363270D1
Authority
DE
Germany
Prior art keywords
complexes
solubilized platinum
platinum
orthophosphate
sulfate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383303687T
Other languages
German (de)
Inventor
Alan R Amundsen
Eric W Stern
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Catalysts LLC
Original Assignee
Engelhard Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Engelhard Corp filed Critical Engelhard Corp
Application granted granted Critical
Publication of DE3363270D1 publication Critical patent/DE3363270D1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Platinum-amines with anti-tumour activity have the formula cis-[Pt(A)2(X)2], wherein A represents a polyhydroxylated amine or A2 represents a polyhydroxylated diamine, and X represents a halide or carboxylate radical or X2 represents a dicarboxylate, sulfate, orthophosphate, or pyrophosphate radical, or a combination of aquo and sulfate, orthophosphate or pyrophosphate.
DE8383303687T 1982-06-28 1983-06-27 Solubilized platinum(ii) complexes Expired DE3363270D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/392,818 US4500465A (en) 1982-06-28 1982-06-28 Solubilized platinum (II) complexes

Publications (1)

Publication Number Publication Date
DE3363270D1 true DE3363270D1 (en) 1986-06-05

Family

ID=23552112

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383303687T Expired DE3363270D1 (en) 1982-06-28 1983-06-27 Solubilized platinum(ii) complexes

Country Status (6)

Country Link
US (1) US4500465A (en)
EP (1) EP0098135B1 (en)
JP (1) JPS5920295A (en)
AT (1) ATE19520T1 (en)
CA (1) CA1263867A (en)
DE (1) DE3363270D1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
EP0167310B1 (en) * 1984-06-27 1991-05-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
US4696918A (en) * 1984-11-02 1987-09-29 Johnson Matthey Public Limited Company Solubilized platinum compound
NZ214504A (en) * 1984-12-17 1988-07-28 American Cyanamid Co Platinum/saccharide complexes and pharmaceutical compositions
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
GB8525689D0 (en) * 1985-10-18 1985-11-20 Johnson Mathey Plc Platinum coordination compounds
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
US4670458A (en) * 1986-01-31 1987-06-02 American Cyanamid Company Hydroxylated 1,2-diaminocyclohexane platinum complexes
US4716157A (en) * 1986-03-20 1987-12-29 American Cyanamid Company Heterocyclic-1,2-diamine platinum complexes
US5206400A (en) * 1986-07-07 1993-04-27 Ohio State University Diastereomeric mono- and di-substituted diamino cyclohexane compounds and the method of preparation thereof
DE3630497A1 (en) * 1986-09-08 1988-03-10 Behringwerke Ag CIS-PLATINUM COMPLEXES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS
JPS63203692A (en) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd Novel platinum complex
JPS63267794A (en) * 1987-04-23 1988-11-04 Sanwa Kagaku Kenkyusho Co Ltd Organic platinum complex and antitumor agent containing the same
US4870070A (en) * 1987-08-10 1989-09-26 American Cyanamid Company Water soluble platinum complexes of novel malonate derivatives
US4904809A (en) * 1987-09-25 1990-02-27 Ss Pharmaceutical Co., Ltd. Platinum complex
JPH01156990A (en) * 1987-09-26 1989-06-20 Ajinomoto Co Inc Novel platium complex and use thereof
AT390065B (en) * 1987-10-08 1990-03-12 Behringwerke Ag cis-Platinum complexes, process for their preparation and pharmaceutical compositions containing these compounds
JPH04502162A (en) * 1989-02-01 1992-04-16 インスチツート、フジチェスコイ、ヒミー、イメーニ、エル、ベー、ピサルゼフスコボ、アカデミー、ナウク、ウクラインスコイ、エスエスエル Platinum 2 derivative with polymethylsiloxane, its production method and antitumor agent based thereon
US4994591A (en) * 1989-06-02 1991-02-19 The Research Foundation Of State University Of Ny Platinum complexes derived from b-silyamines
JP3492763B2 (en) * 1994-06-03 2004-02-03 エスエス製薬株式会社 Platinum complex and therapeutic agent for malignant tumor containing the same
WO2001036431A1 (en) 1999-11-15 2001-05-25 Parker Hughes Institute Diamino platinum (ii) antitumor complexes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605550A5 (en) * 1972-06-08 1978-09-29 Research Corp
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections
US4230631A (en) * 1977-10-19 1980-10-28 Johnson, Matthey & Co., Limited Platinum coordination compounds
NL7810433A (en) * 1977-10-19 1979-04-23 Johnson Matthey Co Ltd NEW PLATINA CONNECTIONS.
US4225529A (en) * 1977-10-19 1980-09-30 Johnson, Matthey & Co., Limited Compositions containing platinum
SE7903361L (en) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd COMPOSITIONS CONTAINING PLATINUM

Also Published As

Publication number Publication date
EP0098135A2 (en) 1984-01-11
EP0098135B1 (en) 1986-04-30
US4500465A (en) 1985-02-19
EP0098135A3 (en) 1984-05-16
JPS5920295A (en) 1984-02-01
ATE19520T1 (en) 1986-05-15
CA1263867A (en) 1989-12-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee