[go: up one dir, main page]

DE3265618D1 - Prolonged-action multiple-layer tablets - Google Patents

Prolonged-action multiple-layer tablets

Info

Publication number
DE3265618D1
DE3265618D1 DE8282108151T DE3265618T DE3265618D1 DE 3265618 D1 DE3265618 D1 DE 3265618D1 DE 8282108151 T DE8282108151 T DE 8282108151T DE 3265618 T DE3265618 T DE 3265618T DE 3265618 D1 DE3265618 D1 DE 3265618D1
Authority
DE
Germany
Prior art keywords
layer
prolonged
active ingredient
action multiple
layer tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282108151T
Other languages
English (en)
Inventor
Yoshimitsu Iida
Atsuko Yoshizawa
Tatuo Kujirai
Toshichika Ogasawara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3265618D1 publication Critical patent/DE3265618D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8282108151T 1981-09-04 1982-09-03 Prolonged-action multiple-layer tablets Expired DE3265618D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56138339A JPS5839618A (ja) 1981-09-04 1981-09-04 持続性積層錠剤

Publications (1)

Publication Number Publication Date
DE3265618D1 true DE3265618D1 (en) 1985-09-26

Family

ID=15219597

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8282108151T Expired DE3265618D1 (en) 1981-09-04 1982-09-03 Prolonged-action multiple-layer tablets
DE198282108151T Pending DE74584T1 (de) 1981-09-04 1982-09-03 Langwirkende mehrschichttablette.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198282108151T Pending DE74584T1 (de) 1981-09-04 1982-09-03 Langwirkende mehrschichttablette.

Country Status (6)

Country Link
US (1) US4454108A (de)
EP (1) EP0074584B1 (de)
JP (1) JPS5839618A (de)
AT (1) ATE14980T1 (de)
CA (1) CA1199870A (de)
DE (2) DE3265618D1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576604A (en) * 1983-03-04 1986-03-18 Alza Corporation Osmotic system with instant drug availability
US4673405A (en) * 1983-03-04 1987-06-16 Alza Corporation Osmotic system with instant drug availability
HU191542B (en) * 1983-04-08 1987-03-30 Boehringer Ingelheim Ltd Process for production of pastiles containing dipyridamel independent from ph with regulated output of the active substance
JPS604120A (ja) * 1983-06-22 1985-01-10 Shionogi & Co Ltd 作用持続型ピナシジル製剤
IE56999B1 (en) * 1983-12-22 1992-03-11 Elan Corp Plc Pharmaceutical formulation
JPS6124516A (ja) * 1984-07-12 1986-02-03 Fujisawa Pharmaceut Co Ltd 持続性錠剤
NL8500724A (nl) * 1985-03-13 1986-10-01 Univ Groningen Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan.
JPH0625055B2 (ja) * 1985-03-18 1994-04-06 日本ケミフア株式会社 持続性錠剤
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
JPS62103012A (ja) * 1985-10-23 1987-05-13 Eisai Co Ltd 多重顆粒
KR950010150B1 (ko) * 1986-01-14 1995-09-11 쥬우가이세이야꾸 가부시끼가이샤 니코란딜 함유 주사제의 안정화 방법
KR940000232B1 (ko) * 1986-01-17 1994-01-12 쥬우가이세이야꾸 가부시끼가이샤 니코란딜 제제의 안정화 방법
US5019302A (en) * 1986-03-12 1991-05-28 Washington University Technology Associates, Inc. Method for granulation
JPS6327424A (ja) * 1986-07-17 1988-02-05 Shionogi & Co Ltd 徐放性製剤およびその製造法
EP0281200B1 (de) * 1987-03-02 1994-01-19 Yamanouchi Europe B.V. Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung
US4786503A (en) * 1987-04-06 1988-11-22 Alza Corporation Dosage form comprising parallel lamine
US5499979A (en) * 1987-06-25 1996-03-19 Alza Corporation Delivery system comprising kinetic forces
US5211958A (en) * 1987-11-30 1993-05-18 Gist-Brocades, N.V. Pharmaceutical composition and process for its preparation
JP2643222B2 (ja) * 1988-02-03 1997-08-20 エーザイ株式会社 多重層顆粒
ATE108996T1 (de) * 1988-02-25 1994-08-15 Brocades Pharma Bv Verfahren zur herstellung eines pharmazeutischen granulats.
GB2256648B (en) * 1991-05-29 1995-08-30 Colorcon Ltd Wax polish composition
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
AU5609998A (en) * 1997-01-10 1998-08-03 Abbott Laboratories Tablet for the controlled release of active agents
JP3718341B2 (ja) 1998-05-12 2005-11-24 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロースとその製造方法
DE19838848A1 (de) 1998-08-26 2000-03-02 Weber & Weber Gmbh & Co Kg Pyrrolizidinalkaloidfreie Petasites enthaltende Zusammensetzung
JP3595765B2 (ja) * 2000-09-27 2004-12-02 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロースを含む乾式直打用基剤
US20040185093A1 (en) * 2003-03-18 2004-09-23 Szymczak Christopher E. Compositions containing sucralose
US20060062811A1 (en) * 2004-09-21 2006-03-23 Szymczak Christopher E Medicinal cooling emulsions
JP2008280251A (ja) * 2007-05-08 2008-11-20 Shin Etsu Chem Co Ltd 多層錠及びその製造方法
US8260695B1 (en) * 2010-07-14 2012-09-04 Steven Rosenberg Secondary power meter for quarter-cycle power measurement and invoicing method
GB201303781D0 (en) 2013-03-04 2013-04-17 Gauthier Pierre Pascal Oral timer device and method of using same
BR112015019776A2 (pt) 2013-03-15 2017-07-18 Braintree Laboratories Inc comprimidos de duplo uso oral em composições farmacêuticas de sais de sulfato e métodos de uso dos comprimidos
CA2936746C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
GB201420306D0 (en) 2014-11-14 2014-12-31 Bio Images Drug Delivery Ltd Compositions
GB201420311D0 (en) * 2014-11-14 2014-12-31 Bio Images Drug Delivery Ltd Pharmaceutical processing
GB201420300D0 (en) 2014-11-14 2014-12-31 Bio Images Drug Delivery Ltd Tablet
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2793979A (en) * 1953-03-30 1957-05-28 Smith Kline French Lab Method of making a sustained release pharmaceutical tablet and product of the method
US2809917A (en) * 1955-10-17 1957-10-15 Victor M Hermelin Sustained release pharmaceutical tablets
US3048526A (en) * 1958-08-04 1962-08-07 Wander Company Medicinal tablet
US3079303A (en) * 1958-12-11 1963-02-26 Smith Kline French Lab Basic tablet granulation and process of using same
US3034911A (en) * 1959-03-25 1962-05-15 Nat Starch Chem Corp Tablet disintegrants
US3096248A (en) * 1959-04-06 1963-07-02 Rexall Drug & Chemical Company Method of making an encapsulated tablet
US2951792A (en) * 1959-11-18 1960-09-06 Smith Kline French Lab Sustained release pharmaceutical tablets
GB972128A (en) * 1960-01-21 1964-10-07 Wellcome Found Pellets for supplying biologically active substances to ruminants and the manufacture of such pellets
GB1022171A (en) * 1961-06-15 1966-03-09 Wellcome Found Prolonged release oral pharmaceutical tablets and their manufacture
BE632692A (de) * 1963-05-28
ES300432A1 (es) * 1963-06-04 1964-11-16 Abbott Lab Procedimiento para producir una composición analgésica
DE1467781A1 (de) * 1963-07-15 1968-12-05 Boehringer Sohn Ingelheim Verfahren zur Herstellung von Dragees mit verlaengerter Wirkstofffreigabe
US3400197A (en) * 1965-01-26 1968-09-03 Robins Co Inc A H Compressible sustained release pharmaceutical tablet lipid-colloidal silica gel matrix fragment granules
US3490742A (en) * 1966-01-14 1970-01-20 Staley Mfg Co A E Compressed tablets
NL159577B (nl) * 1968-02-15 1979-03-15 Organon Nv Werkwijze ter bereiding van snel desintegrerende vaste vormstukken.
US3622677A (en) * 1969-07-07 1971-11-23 Staley Mfg Co A E Compressed tablets containing compacted starch as binder-disintegrant ingredient
US3852421A (en) * 1970-03-23 1974-12-03 Shinetsu Chemical Co Excipient and shaped medicaments prepared therewith
US3632778A (en) * 1970-06-10 1972-01-04 Hoffmann La Roche Tablets containing l-dopa
US4209513A (en) * 1974-02-14 1980-06-24 Burroughs Wellcome Co. Tablet formulation
JPS5163927A (en) * 1974-11-28 1976-06-02 Shinetsu Chemical Co Ketsugoseiryokonajozaihokaizaino seizohoho
US4140755A (en) * 1976-02-13 1979-02-20 Hoffmann-La Roche Inc. Sustained release tablet formulations
DE2904310A1 (de) * 1979-02-05 1980-08-07 Boehringer Mannheim Gmbh Formlinge mit retardierter wirkstofffreisetzung und verfahren zu deren herstellung
US4361545A (en) * 1979-05-21 1982-11-30 Rowell Laboratories, Inc. Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion
US4251518A (en) * 1979-07-03 1981-02-17 Ralston Purina Company Method of preparing readily disintegrable pharmaceutical compositions
US4353887A (en) * 1979-08-16 1982-10-12 Ciba-Geigy Corporation Divisible tablet having controlled and delayed release of the active substance
JPS5911563B2 (ja) * 1980-02-27 1984-03-16 日本原子力研究所 多層構造の徐放性複合体を製造する方法
US4369308A (en) * 1981-07-24 1983-01-18 National Starch And Chemical Corporation Low swelling starches as tablet disintegrants

Also Published As

Publication number Publication date
CA1199870A (en) 1986-01-28
EP0074584B1 (de) 1985-08-21
JPS5839618A (ja) 1983-03-08
JPH0420888B2 (de) 1992-04-07
EP0074584A3 (en) 1983-06-22
DE74584T1 (de) 1984-10-25
EP0074584A2 (de) 1983-03-23
ATE14980T1 (de) 1985-09-15
US4454108A (en) 1984-06-12

Similar Documents

Publication Publication Date Title
DE3265618D1 (en) Prolonged-action multiple-layer tablets
NZ503248A (en) Solid oral dosage form comprising a combination of metformin and glibenclamide
CA2232450A1 (en) Oral pharmaceutical composition containing antimicrobial actives and sustained release pantoprazole
MY104359A (en) Microencapsulated cockroach-controlling composition
JPS57190646A (en) Production of sub-micron particle, obtained particle and drug composition containing same
NZ201182A (en) Delayed release compositions containing bromhexine in the form of spheroidal particles or tablets
JPS56140915A (en) Pharmaceutical preparation for solid drug
DE3473153D1 (en) Maleic acid copolymer, production thereof and scale-preventing agent containing the same
CA2152615A1 (en) Atovaquone pharmaceutical compositions
MY111149A (en) Improved fatty compositions with high solids content.
AU572065B2 (en) P-doped semiconductor alloy and devices
IL77322A (en) Sustained release pharmaceutical compositions containing 1,3-dimethylxanthine and processes for the preparation thereof
AU4233685A (en) Antacid composition
EP0168005A3 (en) Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same
AU614849B2 (en) Butter-like spread
DE3264433D1 (en) Compositions on the basis of 5-hydroxy-tryptophane, manufacturing process and medicaments containing them
DE3277832D1 (en) Composition and method for the preparation of tablets which rapidly disintegrate in an aqueous medium
EP0180190A3 (en) 3,4-dihydrobenzopyran compounds and pharmaceutical composition containing the same
NZ214088A (en) 1,3-diazoles and pharmaceutical compositions
Renecker Bioenergetics and behavior of moose (Alces alces) in the aspen-dominated boreal forest
EP0084053A4 (de) Arzneimittel und die Verwendung von Sn- oder Cr-Protoporphyrin zu dessen Herstellung.
AU545545B2 (en) Uranium peroxide in the form of spherical particles
GB2194786B (en) 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonines and -1,4-benzoxazonines, processes for the preparation thereof and pharmaceutical compositions containing
IL75823A0 (en) 2-benzyl-4-(4-pyridyl)thiazoles and derivatives thereof,their preparation and pharmaceutical compositions containing them
AU589933B2 (en) 8 alpha-acylaminoergoline, its production and pharmaceutical compositions containing it

Legal Events

Date Code Title Description
8364 No opposition during term of opposition