[go: up one dir, main page]

DE19840321A1 - Non-toxic, inexpensive arthropodicide comprises diacid ester, N-methyl-pyrrolidone, caprolactone or glycerol or menthol derivative, effective against insects, mites and ticks, especially dust mites - Google Patents

Non-toxic, inexpensive arthropodicide comprises diacid ester, N-methyl-pyrrolidone, caprolactone or glycerol or menthol derivative, effective against insects, mites and ticks, especially dust mites

Info

Publication number
DE19840321A1
DE19840321A1 DE1998140321 DE19840321A DE19840321A1 DE 19840321 A1 DE19840321 A1 DE 19840321A1 DE 1998140321 DE1998140321 DE 1998140321 DE 19840321 A DE19840321 A DE 19840321A DE 19840321 A1 DE19840321 A1 DE 19840321A1
Authority
DE
Germany
Prior art keywords
mites
glycerol
caprolactone
ticks
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE1998140321
Other languages
German (de)
Inventor
Jochen Kalbe
Guenther Nentwig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to DE1998140321 priority Critical patent/DE19840321A1/en
Publication of DE19840321A1 publication Critical patent/DE19840321A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/10—Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
    • A01N37/04—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof polybasic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/12—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings condensed with a carbocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A01N43/26—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings
    • A01N43/28—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A composition for controlling arthropods contains one or more of: (a) esters derived from aliphatic or aromatic 2-22C dicarboxylic acids and 1-8C aliphatic or aromatic monohydric alcohols; (b) N-methylpyrrolidone; (c) iota -caprolactone; (d) solketal (isopropylidene glycerol) or glycerol formal; and (e) menthyl lactate or menthol glycerol acetal.

Description

Die vorliegende Erfindung betrifft die Verwendung strukturell einfacher, pharmazeu­ tisch zugelassener Hilfsmittel zur Bekämpfung von Arthropoden.The present invention relates to the use of structurally simple, pharma Table-approved aids to combat arthropods.

Die Bekämpfung von Arthropoden, insbesondere von Milben, die sich in Haushalten, Krankenhäusern, aber auch als Ektoparasiten auf Haus- und Nutztieren befinden, ist aus hygienischen Gesichtspunkten von großer Bedeutung.The fight against arthropods, especially mites that live in households, Hospitals, but also located as ectoparasites on domestic and farm animals of great importance from a hygienic point of view.

Die Bekämpfung, insbesondere von Zecken und Milben, erfolgt üblicherweise durch Anwendung von formulierten arthropodiziden Wirkstoffen, z. B. Pyrethrine, Pyre­ throide (z. B. Cypermethrin, Tetramethrin, Permethrin) oder von z. B. Benzylbenzoat. Ebenfalls bekannt ist die insektizide Wirkung von organischen Säuren wie z. B. Octansäure.The control, in particular of ticks and mites, is usually carried out by Use of formulated arthropodicidal agents, e.g. B. Pyrethrine, Pyre throids (e.g. cypermethrin, tetramethrin, permethrin) or from e.g. B. benzyl benzoate. Also known is the insecticidal activity of organic acids such as. B. Octanoic acid.

Die arthropodizide Wirkung von z. B. Diethylenglykolmonoethylether oder Propylen­ glykol oder auch von Alkoholen wie Benzylalkohol oder Octanol, ist ebenfalls be­ kannt geworden (WO 89/12 673, EP-173 229, DE-30 27 144-A1).The arthropodicidal effect of e.g. B. diethylene glycol monoethyl ether or propylene Glycol or alcohols such as benzyl alcohol or octanol is also be became known (WO 89/12 673, EP-173 229, DE-30 27 144-A1).

Es kann jedoch nicht generell gesagt werden, daß alle organischen Lösungsmittel arthropodizid wirksam sind. So stellte sich heraus, daß die meisten organischen Lö­ sungsmittel, wie z. B. Ethanol oder Ethylacetat keine arthropodizide Wirkung zeigen.However, it cannot be said generally that all organic solvents are arthropodicidal. It turned out that most organic solvents means such. B. ethanol or ethyl acetate show no arthropodicidal effect.

Die vorliegende Erfindung betrifft:
Die Verwendung von Verbindungen ausgewählt aus folgenden Gruppen a) bis e):
The present invention relates to:
The use of compounds selected from the following groups a) to e):

  • a) organische Dicarbonsäureester aus aliphatischen oder aromatischen Dicar­ bonsäuren, bestehend aus 2 bis 22 C-Atomen, und aliphatischen oder aromati­ schen Monoalkoholen, bestehend aus 1 bis 8 C-Atomen, a) organic dicarboxylic acid esters from aliphatic or aromatic dicar bonic acids consisting of 2 to 22 carbon atoms, and aliphatic or aromatic monoalcohols, consisting of 1 to 8 carbon atoms,  
  • b) N-Methylpyrrolidon,b) N-methylpyrrolidone,
  • c) ε-Caprolacton,c) ε-caprolactone,
  • d) den Glycerinabkömmlingen Solketal (Isopropylidenglycerol) und Glycerin­ formal,d) the glycerol derivatives Solketal (isopropylidene glycerol) and glycerin formal,
  • e) den Mentholderivaten Menthyllactat und Mentholglycerinacetal,e) the menthol derivatives menthyl lactate and menthol glycerol acetal,

gegebenenfalls in Mischung miteinander oder mit üblichen nicht-arthropodizid wirk­ samen Verdünnungsmitteln zur Bekämpfung von Arthropoden, insbesondere Zecken und Milben, im Haushalt, Hygienebereich und an Tieren.optionally in a mixture with one another or with customary non-arthropodicidal agents seed thinners to control arthropods, especially ticks and mites, in the home, hygiene area and on animals.

Als Dicarbonsäureester eignen sich z. B. Ester der folgenden Dicarbonsäuren:
Oxalsäure, Malonsäure, Maleinsäure, Fumarsäure, Itaconsäure, Bernsteinsäure, Glutarsäure, Adipinsäure, Pimelinsäure, Korksäure, Azelainsäure, Sebacinsäure, Dodecandisäure, Tetradecandisäure, Hexadecandisäure, Docosandisäure, Phthal­ säure, Tetrahydrophthalsäure, Hexahydrophthalsäure, Isophthalsäure, Terephthal­ säure, Glutaminsäure, Asparaginsäure, Isatosäure,
mit den folgenden Alkoholen:
Methanol, Ethanol, Propanol, Isopropanol, n-Butanol, 2-Butanol, tert.-Butanol, 1-Hexanol, 1-Octanol, Furfurylalkohol, Tetrahydrofurfurylalkohol, Cyclohexanol, Allylalkohol, Phenol, Benzylalkohol, Phenylethanol.As dicarboxylic acid esters are, for. B. Esters of the following dicarboxylic acids:
Oxalic acid, malonic acid, maleic acid, fumaric acid, itaconic acid, succinic acid, glutaric acid, adipic acid, pimelic acid, suberic acid, azelaic acid, sebacic acid, dodecanedioic acid, tetradecanedioic acid, docosanedioic acid, phthalic acid, tetrahydrophthalic acid, acidic acid, tetrahydrophthalic acid,
with the following alcohols:
Methanol, ethanol, propanol, isopropanol, n-butanol, 2-butanol, tert-butanol, 1-hexanol, 1-octanol, furfuryl alcohol, tetrahydrofurfuryl alcohol, cyclohexanol, allyl alcohol, phenol, benzyl alcohol, phenylethanol.

Im einzelnen und bevorzugt seien genannt Methyl- und Ethylester von Bernstein­ säure, Phthalsäure, Adipinsäure. In particular and preferably, methyl and ethyl esters from Bernstein may be mentioned acid, phthalic acid, adipic acid.  

Die Verbindungen aus den Gruppen a) bis e) sind strukturell einfache Verbindungen, die pharmazeutisch als Hilfsstoffe zugelassen sind. Sie sind preiswert zugänglich. Über ihre arthropodizide, insbesondere über ihre Wirkung gegen Zecken und Milben, ganz besonders über ihre Wirkung gegen Hausstaubmilben, war bis jetzt noch nichts bekannt. Besonders überraschend war, daß sie in einer Dosis eingesetzt werden kön­ nen, die einer Dosis entspricht, wie man sie vom Einsatz hochpotenter arthropodizi­ der Wirkstoffe kennt, ohne deren toxikologische Wirkung auf Säugetiere zu besitzen.The compounds from groups a) to e) are structurally simple compounds, which are pharmaceutically approved as auxiliary substances. They are inexpensive to access. About their arthropodicides, especially about their activity against ticks and mites, nothing has been particularly special about their effects against dust mites known. It was particularly surprising that they can be used in one dose that corresponds to a dose that can be obtained from the use of highly potent arthropodizi who knows the active ingredients without having their toxicological effects on mammals.

Mittel, die die erfindungsgemäß verwendbaren Verbindungen enthalten, enthalten diese zu 0,1 bis 95 Gew.-%, bevorzugt zu 0,5 bis 50 Gew.-%, besonders bevorzugt zu 1 bis 20 Gew.-%.Agents which contain the compounds which can be used according to the invention 0.1 to 95% by weight, preferably 0.5 to 50% by weight, particularly preferred to 1 to 20 wt .-%.

Bei gleichmäßiger Ausbreitung werden die Mittel so ausgebracht, daß die behandelte Fläche gleichmäßig vom Sprühnebel benetzt wird, d. h. es werden ca. 10 bis 500 ml Wirkstoffiösung pro m2 versprüht. Bevorzugt sind 50 bis 500 ml, besonders bevor­ zugt sind 100 bis 400 ml pro m2. Die Aufwandmenge des Mittels kann durch andere Arten der Ausbringung wie z. B. ULV ( = ultra low volume-Verfahren) weiter ver­ ringert werden.When spreading uniformly, the agents are applied in such a way that the treated area is uniformly wetted by the spray mist, ie approximately 10 to 500 ml of active ingredient solution are sprayed per m 2 . 50 to 500 ml are preferred, particularly preferably 100 to 400 ml per m 2 . The application rate of the agent can by other types of application such. B. ULV (= ultra low volume method) can be further reduced ver.

Mittel und Mischungen, die die erfindungsgemäß verwendbaren Verbindungen ent­ halten, lassen sich unverdünnt oder vorzugsweise verdünnt einsetzen in Form der für Arthropodizide üblichen Formulierungen wie Lösungen, Emulsionen, Suspensionen, Pulver, Schäume, Pasten, Granulate sowie Aerosole.Agents and mixtures containing the compounds which can be used according to the invention hold, can be used undiluted or preferably diluted in the form of Arthropodicidal formulations, such as solutions, emulsions, suspensions, Powders, foams, pastes, granules and aerosols.

Diese Formulierungen werden in bekannter Weise hergestellt, z. B. durch Vermischen der Wirkstoffe mit Hilfs- und/oder Streckmitteln, also flüssigen Lösungsmitteln und/oder festen Trägerstoffen, gegebenenfalls unter Verwendung von oberflächen­ aktiven Mitteln. Im Falle der Verwendung von Wasser als Streckmittel können z. B. auch organische Lösungsmittel als Hilfslösungsmittel verwendet werden. Als flüs­ sige Lösungsmittel kommen im wesentlichen in Frage: Aromaten wie Xylol, Toluol oder Alkylnaphthaline, chlorierte Aromaten der chlorierten aliphatischen Kohlen­ wasserstoffe wie Chlorbenzole, Chlorethylene oder Methylenchlorid, aliphatische Kohlenwasserstoffe wie Cyclohexan oder Paraffine, z. B. Erdölfraktionenn, Alkohole wie Butanol oder Glykol sowie deren Ether und Ester, Ketone wie Aceton, Methyl­ ethylketon, Methylisobutylketon oder Cyclohexanon, stark polare Lösungsmittel wie Dimethylformamid, Dimethylsulfoxid, Dimethylacetamid sowie Wasser.These formulations are prepared in a known manner, e.g. B. by mixing of the active ingredients with auxiliaries and / or extenders, that is to say liquid solvents and / or solid carriers, optionally using surfaces active funds. In the case of the use of water as an extender, e.g. B. organic solvents can also be used as auxiliary solvents. As a river Solvent are essentially in question: aromatics such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics of chlorinated aliphatic carbons  Hydrogen such as chlorobenzenes, chlorethylenes or methylene chloride, aliphatic Hydrocarbons such as cyclohexane or paraffins, e.g. B. petroleum fractions, alcohols such as butanol or glycol and their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents such as Dimethylformamide, dimethyl sulfoxide, dimethylacetamide and water.

Als feste Trägerstoffe seien genannt: z. B. natürliche Gesteinsmehle wie Kaoline, Tonerden, Talkum, Kreide, Quarz, Attapulgit, Montmorillonit oder Diatomeenerde und synthetische Gesteinsmehle wie hochdisperse Kieselsäure, Aluminiumoxid und Silikate. Als feste Trägerstoffe für Granulate kommen in Frage: z. B. gebrochene und fraktionierte natürliche Gesteine wie Calcit, Marmor, Bims, Sepiolith, Dolomit, sowie synthetische Granulate aus anorganischen und organischen Mehlen sowie Gra­ nulate aus organischem Material wie z. B. Sägemehl, Kokosnußschalen, Maiskolben und Tabakstengel.The following may be mentioned as solid carriers: B. natural stone powder such as kaolins, Clay, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth and synthetic stone powder such as finely divided silica, aluminum oxide and Silicates. Possible solid carriers for granules are: B. broken and fractionated natural rocks such as calcite, marble, pumice, sepiolite, dolomite, as well as synthetic granules from inorganic and organic flours as well as gra nulate from organic material such as B. sawdust, coconut shells, corn cobs and tobacco stems.

Als Emulgier- und/oder schaumerzeugende Mittel kommen in Frage: z. B. nichtiono­ gene und anionische Emulgatoren wie Polyoxyethylen-Fettsäure-Ester, Polyoxyethy­ len-Fettalkohöl-Ether, z. B. Alkylarylpolyglykol-Ether, Alkylsulfonate, Alkylsulfate, Arylsulfonate, sowie Eiweißhydrolysate.Suitable emulsifying and / or foam-generating agents are: B. non-iono gene and anionic emulsifiers such as polyoxyethylene fatty acid esters, polyoxyethy len fatty alcohol ether, e.g. B. alkylaryl polyglycol ethers, alkyl sulfonates, alkyl sulfates, Aryl sulfonates, and protein hydrolyzates.

Als Dispergiermittel kommen in Frage: z. B. Lignin-Sulfitablaugen und Methylcellu­ lose.Possible dispersants are: B. Lignin sulfite liquor and methyl cellu loose.

Es können in den Formulierungen Haftmittel wie z. B. Carboxymethylcellulose, natürliche und synthetische, pulverige, körnige oder latexfbrmige Polymere verwen­ det werden wie z. B. Gummiarabicum, Polyvinylalkohol, Polyvinylacetat als auch natürliche Phospholipide wie z. B. Kephaline und Lecithine und synthetische Phos­ pholipide.Adhesives such as e.g. B. carboxymethyl cellulose, Use natural and synthetic, powdery, granular or latex-shaped polymers det be such. B. gum arabic, polyvinyl alcohol, polyvinyl acetate as well natural phospholipids such as B. Kephalins and lecithins and synthetic Phos pholipid.

Weitere Additive können z. B. mineralische und vegetabile Öle sein. Other additives can e.g. B. mineral and vegetable oils.  

Zusätzlich können anorganische Pigmente, z. B. Eisenoxid, Titanoxid, Ferrocyanblau sowie organische Farbstoffe, z. B. Alizarin-, Azo- und Metallphthalocyaninfarbstoffe verwendet werden.In addition, inorganic pigments, e.g. B. iron oxide, titanium oxide, ferrocyan blue as well as organic dyes, e.g. B. alizarin, azo and metal phthalocyanine dyes be used.

Die erfindungsgemäß verwendbaren Stoffe können in Mitteln bevorzugt zur Bekämpfung von Hausstaubmilben, zur Eliminierung von Schimmelpilzen mit Fun­ giziden (z. B. o-Phenylphenolat, Natrium-o-Phenylphenolat) und zur Denaturierung der Allergene mit organischen Säuren (z. B. Tanninsäure) kombiniert werden.The substances which can be used according to the invention can preferably be used in agents Control of house dust mites, for the elimination of molds with fun gicidal (e.g. o-phenylphenolate, sodium o-phenylphenolate) and for denaturing the allergens can be combined with organic acids (e.g. tannic acid).

Die erfindungsgemäß verwendbaren Stoffe und daraus hergestellte Mittel oder Mischungen können mit gutem Erfolg zur Abtötung von schädlichen oder lästigen Arthropoden, insbesondere Spinnentiere und Insekten, verwendet werden.The substances which can be used in accordance with the invention and agents made therefrom or Mixtures can be used successfully to kill harmful or annoying Arthropods, especially arachnids and insects, can be used.

Zu den Spinnentieren gehören Milben (z. B. Sarcoptes scabiei, Dermatophagoides pteronyssinus, Dermatophagoides farinae, Dermanyssus gallinae, Acarus siro) und Zecken (z. B. Ixodes ricinus, Argas refluxus, Ornithodorus moubata, Boophilus microplus, Amblyomma hebraeum, Rhipicephalus sanguineus).Arachnids include mites (e.g. Sarcoptes scabiei, Dermatophagoides pteronyssinus, Dermatophagoides farinae, Dermanyssus gallinae, Acarus siro) and Ticks (e.g. Ixodes ricinus, Argas refluxus, Ornithodorus moubata, Boophilus microplus, Amblyomma hebraeum, Rhipicephalus sanguineus).

Zu den saugenden Insekten gehören im wesentlichen die Stechmücken (z. B. Aedes aegypti, Aedes vexans, Culex quinquefasciatus, Culex tarsalis, Anopheles albimanus, Anopheles stephensi, Mansonia titillans), Schmetterlingsmücken (z. B. Phlebotomus papatasü), Gnitzen (z. B. Culicoides furens), Kriebelmücken (z. B. Simulium damno­ sum), Stechfliegen (z. B. Stomoxys calcitrans), Tsetse-Fliegen (z. B. Glossina morsi­ tans), Bremsen (z. B. Tabanus nigrovittatus, Haematopota pluvialis, Chrysops caecu­ tiens), Echte Fliegen (z. B. Musca domestica, Musca autumnalis, Musca vetustissima, Fannia canicularis), Fleischfliegen (z. B. Sarcophaga carnaria), Myiasis erzeugende Fliegen (z. B. Lucilia cuprina, Chrysomyia chloropyga, Hypoderma bovis, Hypo­ derma lineatum, Dermatobia hominis, Oestrus ovis, Gasterophilus intestinalis, Cochliomyia hominivorax), Wanzen (z. B. Cimex lectularius, Rhodnius prolixus, Triatoma infestans), Läuse (z. B. Pediculus humanis, Haematopinus suis, Damalinea ovis), Flöhe (z. B. Pulex irritans, Xenopsylla cheopis, Ctenocephlides canis, Ctenoce­ phlides felis) und Sandflöhe (Tunga penetrans).The mosquitoes (e.g. Aedes aegypti, Aedes vexans, Culex quinquefasciatus, Culex tarsalis, Anopheles albimanus, Anopheles stephensi, Mansonia titillans), butterfly mosquitoes (e.g. Phlebotomus papatasü), midges (e.g. Culicoides furens), black flies (e.g. Simulium damno sum), sting flies (e.g. Stomoxys calcitrans), tsetse flies (e.g. Glossina morsi tans), brakes (e.g. Tabanus nigrovittatus, Haematopota pluvialis, Chrysops caecu tiens), real flies (e.g. Musca domestica, Musca autumnalis, Musca vetustissima, Fannia canicularis), flesh flies (e.g. Sarcophaga carnaria), myiasis-producing Flies (e.g. Lucilia cuprina, Chrysomyia chloropyga, Hypoderma bovis, Hypo derma lineatum, dermatobia hominis, oestrus ovis, gasterophilus intestinalis, Cochliomyia hominivorax), bugs (e.g. Cimex lectularius, Rhodnius prolixus, Triatoma infestans), lice (e.g. Pediculus humanis, Haematopinus suis, Damalinea  ovis), fleas (e.g. Pulex irritans, Xenopsylla cheopis, Ctenocephlides canis, Ctenoce phlides felis) and sand fleas (Tunga penetrans).

Zu den beißenden Insekten gehören im wesentlichen Schaben (z. B. Blattella germa­ nica, Periplaneta americana, Blatta orientalis, Supella longipalpa), Käfer (z. B. Sitio­ philus granarius, Tenebrio molitor, Dermestes lardarius, Stegobium paniceum, Ano­ bium punctatum, Hylotrupes bajulus), Termiten (z. B. Reticulitermes lucifugus), Ameisen (z. B. Lasius niger, Monomorium pharaonis), Wespen (z. B. Vespula germa­ nica) und Larven von Motten (z. B. Ephestia elutella, Ephestia cautella, Plodia inter­ punctella, Hofmannophila pseudospretella, Tineola bisselliella, Tinea pellionella, Trichophaga tapetzella).Biting insects essentially include cockroaches (e.g. Blattella germa nica, Periplaneta americana, Blatta orientalis, Supella longipalpa), beetles (e.g. Sitio philus granarius, Tenebrio molitor, Dermestes lardarius, Stegobium paniceum, Ano bium punctatum, Hylotrupes bajulus), termites (e.g. Reticulitermes lucifugus), Ants (e.g. Lasius niger, Monomorium pharaonis), wasps (e.g. Vespula germa nica) and larvae of moths (e.g. Ephestia elutella, Ephestia cautella, Plodia inter punctella, Hofmannophila pseudospretella, Tineola bisselliella, Tinea pellionella, Trichophaga tapetzella).

Bevorzugt werden die erfindungsgemäßen Wirkstoffe gegen Spinnentiere, vor allem der Ordnung Acari und ganz besonders bevorzugt gegen die Unterordnungen Sar­ coptiformes und Parasitiformes eingesetzt.The active compounds according to the invention are preferred against arachnids, in particular of the order Acari and especially preferred against the subordinates Sar coptiformes and parasitiformes used.

Die folgenden Beispiele für die Zubereitungen und die Verwendung der erfindungs­ gemäßen Mittel dienen der weiteren Erläuterung der Erfindung. The following examples of the preparations and the use of the Invention Appropriate means serve to further explain the invention.  

Beispiel 1example 1

Ein wasserbasierendes Pumpspray zur Behandlung von Unterlagen wird hergestellt durch Vermischen von 10 Teilen einer der erfindungsgemäß verwendbaren Verbin­ dungen, 47 Teilen Isopropanol und 43 Teilen Wasser.A water-based pump spray for the treatment of documents is produced by mixing 10 parts of one of the compounds which can be used according to the invention dung, 47 parts isopropanol and 43 parts water.

Beispiel 2Example 2

Ein Mittel in Form eines Aerosols zum Aussprühen auf Unterlagen setzt sich aus 10 Teilen einer der erfindungsgemäß verwendbaren Verbindungen, 11 Teilen Kero­ sin deod., 38,8 Teilen Isopropanol, 0,2 Teilen Parfüm und 40% Propan/Butan (Ver­ hältnis 15 : 85) zusammen.An agent in the form of an aerosol for spraying on substrates exposes itself 10 parts of one of the compounds which can be used according to the invention, 11 parts of Kero sin deod., 38.8 parts isopropanol, 0.2 parts perfume and 40% propane / butane (Ver ratio 15: 85) together.

Biologische WirksamkeitBiological effectiveness

Die folgenden biologischen Beispiele belegen die Wirksamkeit der erfindungsgemä­ ßen Wirkstoffe:The following biological examples demonstrate the effectiveness of the invention active ingredients:

Methodemethod

Es wird eine gemischte Population der Art Dermatophagoides pteronyssinus ver­ wendet.A mixed population of the species Dermatophagoides pteronyssinus ver turns.

Eine Kunststoffschale (7 cm ∅, 3 cm hoch) wird am oberen Innenrand mit Leim ver­ sehen und anschließend mit einem Stück Matratzenstoff gleichen Durchmessers belegt. Auf diesen wird eine Spatelspitze aus einer Anzuchtschale gegeben, die Mil­ ben und Futter (Tetramin gemahlen) enthält.A plastic bowl (7 cm ∅, 3 cm high) is glued to the upper inner edge see and then with a piece of mattress fabric of the same diameter busy. A spatula tip from a growth tray is placed on this, the Mil ben and feed (ground tetramine) contains.

Anschließend wird die Schale in einen Kunststoffbehälter (33 × 22 cm, Höhe 6,5 cm), der gesättigte Kochsalzlösung enthält, auf eine umgedrehte Petrischale gestellt und der Behälter mit einem Deckel verschlossen. Then the bowl is placed in a plastic container (33 × 22 cm, height 6.5 cm), which contains saturated saline, on an inverted petri dish placed and the container closed with a lid.  

Am nächsten Tag werden 0,4 ml des in Ethanol gelösten Testwirkstoffs auf den Stoff aufgesprüht.The next day, 0.4 ml of the test drug dissolved in ethanol is applied to the fabric sprayed on.

Es herrscht Tageslichtbeleuchtung, die Temperatur beträgt 24 bis 26°C, die relative Luftfeuchte in dem geschlossenen Kunststoffbehälter ca. 75%.There is daylight lighting, the temperature is 24 to 26 ° C, the relative Air humidity in the closed plastic container approx. 75%.

Es wird nach 1, 3, 7, 14, 21 und 28 Tagen unter dem Binokular der Zustand der Mil­ ben im Vergleich zu einer nur mit Ethanol behandelten Kontrolle bonitiert (3 = viele Milben, 0 = keine Milben). Ein direktes Auszählen ist nicht möglich, da von den toten Tieren nur wenige zu sehen sind.After 1, 3, 7, 14, 21 and 28 days the status of the mil ben compared to a control treated only with ethanol (3 = many Mites, 0 = no mites). Direct counting is not possible because of the only a few dead animals can be seen.

Bei Bedarf (Kontrolle, unwirksame Präparate) wird Futter nachgegeben.If necessary (control, ineffective preparations), feed is added.

Von jedem Versuch werden 3 Versuchsglieder angelegt und nach Versuchsende die Summe aus den Bonitierungen festgehalten.3 test elements are created from each test and the test elements are added at the end of the test Sum of the ratings recorded.

ErgebnisseResults

Temperatur: 24 bis 26°C; relative Luftfeuchte im Kunststoffbehälter: ca. 75%. Temperature: 24 to 26 ° C; relative humidity in the plastic container: approx. 75%.  

Tabelle 1 Table 1

Claims (1)

Mittel zur Bekämpfung von Arthropoden, dadurch gekennzeichnet, daß es Verbindungen ausgewählt aus einer oder mehreren der folgenden Gruppen a) bis e) enthält:
  • a) organische Dicarbonsäureester aus aliphatischen oder aromatischen Dicarbonsäuren, bestehend aus 2 bis 22 C-Atomen, und aliphatischen oder aromatischen Monoalkoholen, bestehend aus 1 bis 8 C-Atomen,
  • b) N-Methylpyrrolidon,
  • c) ε-Caprolacton,
  • d) den Glycerinabkömmlingen Solketal (Isopropylidenglycerol) und Glycerinformal,
  • e) den Mentholderivaten Menthyllactat und Mentholglycerinacetal.
Agent for combating arthropods, characterized in that it contains compounds selected from one or more of the following groups a) to e):
  • a) organic dicarboxylic acid esters of aliphatic or aromatic dicarboxylic acids, consisting of 2 to 22 C atoms, and aliphatic or aromatic monoalcohols, consisting of 1 to 8 C atoms,
  • b) N-methylpyrrolidone,
  • c) ε-caprolactone,
  • d) the glycerol derivatives Solketal (isopropylidene glycerol) and glycerol formal,
  • e) the menthol derivatives menthyl lactate and menthol glycerol acetal.
DE1998140321 1998-09-04 1998-09-04 Non-toxic, inexpensive arthropodicide comprises diacid ester, N-methyl-pyrrolidone, caprolactone or glycerol or menthol derivative, effective against insects, mites and ticks, especially dust mites Withdrawn DE19840321A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE1998140321 DE19840321A1 (en) 1998-09-04 1998-09-04 Non-toxic, inexpensive arthropodicide comprises diacid ester, N-methyl-pyrrolidone, caprolactone or glycerol or menthol derivative, effective against insects, mites and ticks, especially dust mites

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1998140321 DE19840321A1 (en) 1998-09-04 1998-09-04 Non-toxic, inexpensive arthropodicide comprises diacid ester, N-methyl-pyrrolidone, caprolactone or glycerol or menthol derivative, effective against insects, mites and ticks, especially dust mites

Publications (1)

Publication Number Publication Date
DE19840321A1 true DE19840321A1 (en) 2000-03-09

Family

ID=7879780

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1998140321 Withdrawn DE19840321A1 (en) 1998-09-04 1998-09-04 Non-toxic, inexpensive arthropodicide comprises diacid ester, N-methyl-pyrrolidone, caprolactone or glycerol or menthol derivative, effective against insects, mites and ticks, especially dust mites

Country Status (1)

Country Link
DE (1) DE19840321A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008162943A (en) * 2006-12-28 2008-07-17 Nachiyuraru Network:Kk Food insect pest repellent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008162943A (en) * 2006-12-28 2008-07-17 Nachiyuraru Network:Kk Food insect pest repellent

Similar Documents

Publication Publication Date Title
EP0279325B1 (en) (+)-1r-trans-2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylic acid 2,3,5,6-tetrafluorobenzyl ester
US6147091A (en) Arthropod repellant
EP0289842B1 (en) Remedy against insects and mites
EP0467045A2 (en) Morpholino urea derivatives
US4950682A (en) Arthropodicidal compositions
EP0346709B1 (en) Use of acylate -aminoacidester derivates as insect and mite repellent
HK1003968B (en) Arthropodicidal compositions
DD267901A5 (en) INSECT AND MITIGATIVE EMPLOYMENT
MX2014009441A (en) Active compound compositions for vector control of insecticide-resistant pests.
EP0477676B1 (en) Combination of pyrethroid agents containing benfluthrin and prallethrin
DE2530070A1 (en) INSECT REPELLENT
DE2805050A1 (en) PEST CONTROL
DE19840321A1 (en) Non-toxic, inexpensive arthropodicide comprises diacid ester, N-methyl-pyrrolidone, caprolactone or glycerol or menthol derivative, effective against insects, mites and ticks, especially dust mites
DE19917948A1 (en) Arthropodicidal mixture of polyorganosiloxane, hydrogen peroxide and organic solvent, useful for controlling mites or ticks, e.g. house dust mites and ectoparasites
WO2019229060A1 (en) Microcapsule formulations containing transfluthrin as a volatile insecticide with an increased effect
DE19627778A1 (en) Arthropod repellant
EP2394511B1 (en) Synergistic mixtures of alpha, omega-amino alcohol enantiomers, their production and use of in preparations for combating insects and mites
MXPA98008961A (en) Repellents against artropo
DE19703133A1 (en) Attractants for arthropods
DE2166232A1 (en) Phenyl acetic acid derivs - synergistic agents for insecticides
DD281340A5 (en) MEANS OF INSECT AND MILFEN DEFENSE

Legal Events

Date Code Title Description
8130 Withdrawal