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DE1795727A1 - Derivate des cephalosporin c - Google Patents

Derivate des cephalosporin c

Info

Publication number
DE1795727A1
DE1795727A1 DE19621795727 DE1795727A DE1795727A1 DE 1795727 A1 DE1795727 A1 DE 1795727A1 DE 19621795727 DE19621795727 DE 19621795727 DE 1795727 A DE1795727 A DE 1795727A DE 1795727 A1 DE1795727 A1 DE 1795727A1
Authority
DE
Germany
Prior art keywords
salt
cephalosporin
thiouronium
solution
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19621795727
Other languages
German (de)
English (en)
Inventor
St Peter Buckinghamsh Chalfont
John Derek Cocker
James Stuart Gordon Cox
Harry Fazackerley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB17845/61A external-priority patent/GB1012943A/en
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of DE1795727A1 publication Critical patent/DE1795727A1/de
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01GHORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
    • A01G17/00Cultivation of hops, vines, fruit trees, or like trees
    • A01G17/04Supports for hops, vines, or trees
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26BHAND-HELD CUTTING TOOLS NOT OTHERWISE PROVIDED FOR
    • B26B3/00Hand knives with fixed blades
    • B26B3/08Hand knives with fixed blades specially adapted for cutting cardboard, or wall, floor, or like covering materials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Forests & Forestry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Environmental Sciences (AREA)
  • Cephalosporin Compounds (AREA)
DE19621795727 1961-05-16 1962-05-15 Derivate des cephalosporin c Pending DE1795727A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB17845/61A GB1012943A (en) 1961-05-16 1961-05-16 Improvements in or relating to antibiotics
GB302662 1962-01-26

Publications (1)

Publication Number Publication Date
DE1795727A1 true DE1795727A1 (de) 1974-04-04

Family

ID=26237945

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19621795727 Pending DE1795727A1 (de) 1961-05-16 1962-05-15 Derivate des cephalosporin c
DE19621745624 Expired DE1745624C3 (de) 1961-05-16 1962-05-15 Verfahren zur Herstellung von Derivaten des Cephalosporin C

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19621745624 Expired DE1745624C3 (de) 1961-05-16 1962-05-15 Verfahren zur Herstellung von Derivaten des Cephalosporin C

Country Status (9)

Country Link
JP (1) JPS3917936B1 (no)
AT (2) AT265520B (no)
BE (1) BE617687A (no)
CH (3) CH520709A (no)
DE (2) DE1795727A1 (no)
DK (1) DK128611B (no)
FR (1) FR2030M (no)
NO (1) NO133673C (no)
SE (1) SE317380B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE16706T1 (de) * 1980-09-19 1985-12-15 Asahi Chemical Ind Verfahren zur herstellung von cephalosporinverbindungen.
JPS5762284A (en) * 1980-10-01 1982-04-15 Sumitomo Chem Co Ltd Stabilizing method
FR2530248A1 (fr) * 1982-07-13 1984-01-20 Sanofi Sa Nouveaux derives des cephalosporines, leur procede de preparation et medicaments antibiotiques contenant lesdits derives
AU2002316862A1 (en) * 2001-04-19 2002-11-05 Bioferma Murcia, S.A. Enzymatic process for preparing cephalosporin derivatives

Also Published As

Publication number Publication date
NO133673B (no) 1976-03-01
CH565184A5 (no) 1975-08-15
CH520709A (de) 1972-03-31
DE1795484A1 (de) 1974-09-19
DE1795484B2 (de) 1975-09-04
CH554371A (de) 1974-09-30
FR2030M (fr) 1963-10-25
BE617687A (fr) 1962-11-16
AT265520B (de) 1968-10-10
SE317380B (no) 1969-11-17
DE1745624C3 (de) 1974-12-12
AT265513B (de) 1968-10-10
DE1745624B2 (de) 1974-05-16
DK128611B (da) 1974-06-04
NO133673C (no) 1976-06-09
JPS3917936B1 (no) 1964-08-25
DE1745624A1 (de) 1972-02-17

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