DE1645922A1 - Verfahren zur Herstellung von N,N'-Bis-halogenalkylphosphorsaeure-und -thiophosphorsaeureesteramiden - Google Patents
Verfahren zur Herstellung von N,N'-Bis-halogenalkylphosphorsaeure-und -thiophosphorsaeureesteramidenInfo
- Publication number
- DE1645922A1 DE1645922A1 DE19661645922 DE1645922A DE1645922A1 DE 1645922 A1 DE1645922 A1 DE 1645922A1 DE 19661645922 DE19661645922 DE 19661645922 DE 1645922 A DE1645922 A DE 1645922A DE 1645922 A1 DE1645922 A1 DE 1645922A1
- Authority
- DE
- Germany
- Prior art keywords
- acid
- bis
- molecular weight
- low molecular
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052757 nitrogen Inorganic materials 0.000 title claims description 6
- 239000002253 acid Substances 0.000 title claims description 5
- -1 thiophosphoric acid ester amides Chemical class 0.000 title claims 2
- 238000000034 method Methods 0.000 title description 3
- 238000002360 preparation method Methods 0.000 title description 2
- 125000005843 halogen group Chemical group 0.000 claims description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 4
- 229910052760 oxygen Inorganic materials 0.000 claims description 4
- 239000001301 oxygen Substances 0.000 claims description 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 3
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- 229910052739 hydrogen Inorganic materials 0.000 claims description 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 2
- 239000001257 hydrogen Substances 0.000 claims description 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims description 2
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 claims description 2
- 125000001841 imino group Chemical group [H]N=* 0.000 claims description 2
- 239000012442 inert solvent Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 229910052717 sulfur Inorganic materials 0.000 claims description 2
- 239000011593 sulfur Substances 0.000 claims description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 125000001340 2-chloroethyl group Chemical group [H]C([H])(Cl)C([H])([H])* 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 235000015243 ice cream Nutrition 0.000 description 1
- PGYPOBZJRVSMDS-UHFFFAOYSA-N loperamide hydrochloride Chemical compound Cl.C=1C=CC=CC=1C(C=1C=CC=CC=1)(C(=O)N(C)C)CCN(CC1)CCC1(O)C1=CC=C(Cl)C=C1 PGYPOBZJRVSMDS-UHFFFAOYSA-N 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65848—Cyclic amide derivatives of acids of phosphorus, in which two nitrogen atoms belong to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/564—Three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEA0052990 | 1966-07-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1645922A1 true DE1645922A1 (de) | 1971-01-28 |
Family
ID=6938756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19661645922 Pending DE1645922A1 (de) | 1966-07-11 | 1966-07-11 | Verfahren zur Herstellung von N,N'-Bis-halogenalkylphosphorsaeure-und -thiophosphorsaeureesteramiden |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT265313B (xx) |
| BE (1) | BE700713A (xx) |
| CH (1) | CH484200A (xx) |
| DE (1) | DE1645922A1 (xx) |
| DK (1) | DK121232B (xx) |
| GB (1) | GB1190054A (xx) |
| IL (1) | IL28262A (xx) |
| NL (1) | NL158182B (xx) |
| SE (1) | SE327203B (xx) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL140732B1 (en) * | 1984-07-31 | 1987-05-30 | Polska Akad Nauk Centrum | Method of obtaining 2-/2-halogenethylamino/-2-oxo-3-/2-halogenethylo/-1,3,2-oxazophosphorianytes |
-
1966
- 1966-07-11 DE DE19661645922 patent/DE1645922A1/de active Pending
-
1967
- 1967-06-27 AT AT597867A patent/AT265313B/de active
- 1967-06-30 BE BE700713D patent/BE700713A/xx not_active IP Right Cessation
- 1967-06-30 SE SE997167A patent/SE327203B/xx unknown
- 1967-07-05 IL IL2826267A patent/IL28262A/en unknown
- 1967-07-07 CH CH967467A patent/CH484200A/de not_active IP Right Cessation
- 1967-07-10 DK DK353567A patent/DK121232B/da not_active IP Right Cessation
- 1967-07-11 NL NL6709607A patent/NL158182B/xx not_active IP Right Cessation
- 1967-07-11 GB GB3184867A patent/GB1190054A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL28262A (en) | 1971-05-26 |
| SE327203B (xx) | 1970-08-17 |
| BE700713A (xx) | 1967-12-01 |
| NL158182B (nl) | 1978-10-16 |
| DK121232B (da) | 1971-09-27 |
| CH484200A (de) | 1970-01-15 |
| GB1190054A (en) | 1970-04-29 |
| AT265313B (de) | 1968-10-10 |
| NL6709607A (xx) | 1968-01-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE2065234B2 (de) | Phosphorsäureestersalze, ihre Herstellung und Verwendung | |
| DE2166717A1 (de) | Verfahren zur herstellung von arabinofuranosylverbindungen | |
| DE1445186C3 (de) | 3,3'-Di-2-imidazolin-2-yl-carbanilid | |
| DE3122814A1 (de) | "n(pfeil hoch)6(pfeil hoch)-((2-hydroxypropyl)aryl)adenosine oder -adenine, verfahren zu deren herstellung sowie diesselben enthaltende pharmazeutische praeparate" | |
| DE2357847A1 (de) | Verfahren zur herstellung von n tief 1-(2'-furanidyl)- und n tief 1(2'-pyranidyl)-urazilen | |
| DE1645922A1 (de) | Verfahren zur Herstellung von N,N'-Bis-halogenalkylphosphorsaeure-und -thiophosphorsaeureesteramiden | |
| DE2000030C3 (de) | 3-Alkoxy-und 3-Phenoxy-2-(diphenylhydroxy)methyl-propylamine und diese enthaltende Arzneimittel | |
| AT391699B (de) | Verfahren zur herstellung neuer 4-chloro substituierter furo-(3,4-c)-pyridinderivate | |
| DE2716172C2 (de) | Bis(6-[(hexahydro-1H-azepin-1-yl)-methylenamino]-penicillanoyloxy)-methan, seine Herstellung und dieses enthaltendes Arzneimittel | |
| CH649998A5 (de) | Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff. | |
| DE2520131A1 (de) | Stickstoffhaltige polycyclische verbindungen und verfahren zu deren herstellung | |
| CH620208A5 (en) | Process for the preparation of anticarcinogenic dianhydrohexitide-acyl derivatives | |
| DE2559558C3 (de) | Apovincaminsäureamide, deren Salze mit Säuren, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel | |
| DE1136341B (de) | Verfahren zur Herstellung des Natrium- oder Kaliumsalzes des N-[5'-Nitrofurfuryliden-(2')]-1-aminohydantoins | |
| DE2147852A1 (de) | Neue Penicilline und Verfahren zu deren Herstellung | |
| AT247519B (de) | Verfahren zur Herstellung neuer Additionsverbindungen von Antibiotika | |
| DE1670378C (de) | Verfahren zur Herstellung des Salzes aus4-n-Butyl-3,5-dioxo-l,2-diphenylpyrazolidin und dem beta-Diäthylamino-äthylamid der p-Chlorphenoxyessigsäure | |
| DE1468863C (de) | Verfahren zur Herstellung von N n Butyl N (3 chlor 4 sulfamidophenyl) benzamidinen | |
| DE1188583B (de) | Verfahren zur Herstellung der Steroisomeren und des Racemats von Butan-1, 2, 3, 4-tetrol-1, 4-di-(methansulfonat) | |
| DE2404924A1 (de) | Ergolinderivate | |
| AT256102B (de) | Verfahren zur Herstellung von neuen disubstituierten Isoxazol-Derivaten und ihren Salzen | |
| DE1620054C (de) | Verfahren zur Herstellung von Chinolindenvaten sowie diese Ver bindungen enthaltende Arzneimittel Ausscheidung aus 1470047 | |
| DE3784883T2 (de) | Fluor enthaltende makrolid-verbindungen, pharmazeutische zusammensetzungen, welche diese enthalten und ihre verwendung fuer die herstellung von arzneimitteln. | |
| DE2406817A1 (de) | Penicillin- und cephalosporinester, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen | |
| DE1795125C (de) | Chinolinderivate, ein Verfahren zu ihrer Herstellung und Arzneimittel |