DE1517903C3 - Method for manufacturing a capillary membrane dialyzer - Google Patents

Description

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Further examples form the coating of a niche contact, so that now in the sense of the invention

Core capillary by means of cellulose-copper oxide ammonia the detachment of the core capillary take place

niak solution and precipitation of the. concerned can. As I said, this detachment takes place

Layer. in the acidic bath in a known manner to the BiI- by that one special for the core capillary material

formation of hydrate cellulose or the coating 5 specific organic solvent through the core

¹ passes through one with corresponding hardness and solution capillaries, through which the latter

medium-sized silicone rubber solution, which is removed from the inside in a radial direction

Drying out of the solvent and after chemi-. In the above example, in which the core cable

shear action of the hardening agent a polymeric pillars made of polystyrene, can be used as a specific

silicone rubber skin on the core capillary erioic solvent such as chlorinated hydrocarbons

testifies. fabrics are used.

Capillary membranes obtained in this way can now be It goes without saying that the solubility of the core chamber together with its core capillaries are embedded at the end in the pill material and in the bores of the membranes provided at the end with one or more layers of separating walls for forming the capillary. This embedded substance is as different as possible. Contribution is done in such a way that the bore through- 'for example, collodion wool in an alcohol knife is selected to be larger than the outer diameter-ether mixture, but polystyrene is not. The denitrated collodion wool, that is to say the holes inserted and then coated with a hydrate cellulose, is insoluble in organic carbon cast or spreadable embedding substance, such as hydrogen, while polystyrene is soluble in these e.g. B. thermosetting resin or silicone rubber, is tight. ..
cemented into the holes. In the case of a subsequent conversion, the capillary membranes are pushed into the bores on the core capillaries. B. tweezers, the necessary chemical and / or physical conditions are required, since the core capillary located therein has a mechanical action even after it has been embedded in the mechanical support. Partition wall holes within the overall arrangement

Subsequent to hardening of the embedding substance, and either before or after

The capillary membranes do not cause any further mechanical detachment of the core capillaries.

Claims (3)

1 ül / OVD 1 2 initially mentioned type that these claims: Avoids difficulties, d. H. both the production of thin-walled capillary membranes and 1. Process for the production of a capillary whose undamaged embedding in the partition membrane dialyzer, in which a multitude of 5 holes facilitates. Capillary membranes with their open ends are used in accordance with the invention for this purpose Bores of two opposite see patent specification 1047 984 known method Partitions in potting material od are, characterized, fen for the production of multi-layer threads that one first serves the capillary membranes under io. In this process are used to achieve Application of the method produced, later before- mixed with several separate dining rooms and / or physically easily detachable bonded coaxial spinning tubes Kernka-Kernkapillaren to coat, then the capillary from a chemically or physically wenilar membrane together with the resilient material still in it, such as B. glass, with Chen core capillaries into the partition bores 15 of a more resistant substance, e.g. B. a embedded and then coated by the core cap- noble metal, which later becomes one of the colars a physical and / or chemical axial spinning tube forms, whereupon the less Lets solvent flow through. Resistant material is extracted. 2. Manufacturing method according to claim 1, according to the invention, the task set is accordingly characterized in that the training is solved according to that first the cap or multilayered capillary membranes on the membrane using the method er core capillaries by producing them, it happens later chemically and / or physically easily To coat core capillaries one or more times with a removable core capillary, then Solution of a substance coats that only afterwards affects the capillary membranes together with those still in them through a chemical and / or physically sensitive core capillary into the partition wall niche Treatment to the actual membrane embeds and then through the Kernkapilsubstaiiz is transformed. a physical and / or chemical solution 3. Manufacturing method according to claim 2, which allows agent to flow through. characterized in that the chemical and / The core capillaries facilitate on the one hand very much or physical treatment of the first to 3 ° significantly the formation of the capillary membranes, for The substance (s) applied to the core capillaries enable them to be embedded in the other only after the capillary membranes have been embedded in the partition wall bores to the greatest possible extent the bores in the partition wall before or after the otherwise existing damage the detachment of the core capillaries, experience. Your wall thickness can be much greater for this purpose follows. 35 than that of the actual capillary membrane nen. You can melt in a known manner can be produced from thermoplastics by spinning. According to one embodiment of the invention The invention relates to a method for the formation of single or multi-layer Ka production of a capillary membrane dialyzer, with 40 pillar membranes on the core capillaries, a large number of capillary membranes with their layers can be seen by opening or closing the core capillaries pulls the bores of two dividing walls in potting material which are overlaid with a solution of a substance and which are only subsequently embedded by a chemical or the like. and / or physical treatment to produce the actual capillary membrane dialyzer. In this context, US Pat. No. 3,228,877 suggests that the transformation before or after the embedding of the roofing is known. It serves to separate different pillar membranes into the bores in the partition wall, in components of a liquid mixture, as for example in the latter case also only after the removal of the "artificial kidney" for blood dialysis. In the final core capillaries. y rem case, in which in the intra-capillary space this is 5 °, for example, a melt-spun, cleansing blood and in the intercapillary space the polystyrene core capillary of 0.5 mm dialysis fluid flows, the capillary arm outer diameter and 80 micron wall thickness are made of hydrated cellulose, for example . The production of such devices raises two kinds of product wool, led out of this bath, and poses problems: On the one hand, the production of thin, dried and small-diameter, aqueous sodium-walled hollow capillaries from sulfhydrate solution post-treated, as a result of which their membrane substances suitable for dialysis are denitrated. In the process, (the thickness of the capillary wall in the example of the core capillary during the denitration process - blood dialysis should be less than 25 microns with a capillary diameter of less than 1 mm initially still made of collodion wool) 60 the very thin-walled capillary membrane, which is difficult in itself. On the other hand, it provides, for example, a thickness of 5 microns with the stability required for denitry problems, such a thin-walled capillary milling process,
Burn stably and tightly into the bores in the partition wall The coating of the core capillary (in the example to be used without damaging just a single one of the natural with collodion wool solution), the drying of the large number of these capillary membranes of a layer applied and their chemical follow-up dialyzer. treatment (denitration in the example) The object of the invention is to provide a method to be repeated several times in order to produce a capillary membrane dialyzer of a multilayered capillary membrane in this way.