DE122008000035I1 - Rekombinante influenzaviren zur vakzinherstellung und gentherapie - Google Patents

Rekombinante influenzaviren zur vakzinherstellung und gentherapie

Info

Publication number: DE122008000035I1
Authority: DE; Germany
Prior art keywords: vaccination; gene therapy; influenza viruses; recombinant influenza; viruses
Prior art date: 1999-04-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

DE122008000035C

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wisconsin Alumni Research Foundation

Original Assignee

Wisconsin Alumni Research Foundation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-06

Filing date

2000-04-05

Publication date

2009-05-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26826080&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122008000035(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-04-05 Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation

2009-05-20 Publication of DE122008000035I1 publication Critical patent/DE122008000035I1/de

Status Pending legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16123—Virus like particles [VLP]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16141—Use of virus, viral particle or viral elements as a vector
- C12N2760/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6072—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
- C12N2810/6081—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses rhabdoviridae, e.g. VSV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
Biophysics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Veterinary Medicine (AREA)
Physics & Mathematics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pulmonology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DE122008000035C 1999-04-06 2000-04-05 Rekombinante influenzaviren zur vakzinherstellung und gentherapie Pending DE122008000035I1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US12791299P	1999-04-06	1999-04-06
US13283999P	1999-05-06	1999-05-06
PCT/US2000/009021 WO2000060050A2 (en)	1999-04-06	2000-04-05	Recombinant influenza viruses for vaccines and gene therapy

Publications (1)

Publication Number	Publication Date
DE122008000035I1 true DE122008000035I1 (de)	2009-05-20

Family

ID=26826080

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
DE60035778T Expired - Lifetime DE60035778T2 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE122008000061C Pending DE122008000061I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE122008000035C Pending DE122008000035I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE200812000014 Pending DE122008000014I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie.
DE122008000058C Pending DE122008000058I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE201112100037 Pending DE122011100037I1 (de)	1999-04-06	2011-07-26	Rekombinante influenzaviren zur vakzinherstellung und gentherapie.

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
DE60035778T Expired - Lifetime DE60035778T2 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE122008000061C Pending DE122008000061I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
DE200812000014 Pending DE122008000014I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie.
DE122008000058C Pending DE122008000058I1 (de)	1999-04-06	2000-04-05	Rekombinante influenzaviren zur vakzinherstellung und gentherapie
DE201112100037 Pending DE122011100037I1 (de)	1999-04-06	2011-07-26	Rekombinante influenzaviren zur vakzinherstellung und gentherapie.

Country Status (19)

Country	Link
EP (4)	EP1820853B1 (de)
JP (3)	JP5543048B2 (de)
KR (1)	KR100702275B1 (de)
CN (2)	CN1350578B (de)
AT (2)	ATE368729T1 (de)
AU (1)	AU4073300A (de)
BR (1)	BRPI0009580B8 (de)
CA (2)	CA2928263A1 (de)
CY (2)	CY1108520T1 (de)
DE (6)	DE60035778T2 (de)
DK (3)	DK1820853T3 (de)
ES (3)	ES2533622T3 (de)
FR (1)	FR11C0027I2 (de)
HK (1)	HK1214298A1 (de)
IL (2)	IL145702A0 (de)
MX (1)	MXPA01010082A (de)
NL (2)	NL300365I2 (de)
PT (2)	PT1185615E (de)
WO (1)	WO2000060050A2 (de)

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BRPI0307679A2 (pt)	2002-02-13	2016-11-08	Wisconsin Alumni Res Found	vetor viral de influenza, vírus recombinate de influenza, molécula isolada de ácido nucleico e métodos para expressar um segmento heterólogo de ácido nucleico em uma célula e para preparar vírus semelhante a influenza incompetente na replicação.
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CN101379183B (zh)	2004-12-24	2013-07-03	雅培生物学有限责任公司	流感病毒的拯救
EP1856271A4 (de)	2005-03-08	2009-11-18	Medimmune Vaccines Inc	Influenza-hämagglutinin- und neuraminidase-varianten
US11707520B2 (en)	2005-11-03	2023-07-25	Seqirus UK Limited	Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture
AU2006310339B2 (en)	2005-11-04	2013-01-10	Novartis Ag	Influenza vaccines including combinations of particulate adjuvants and immunopotentiators
AU2006310337B9 (en)	2005-11-04	2013-11-28	Novartis Ag	Adjuvanted influenza vaccines including cytokine-inducing agents
EA014028B1 (ru)	2005-11-04	2010-08-30	Новартис Вэксинс Энд Диагностикс Срл	Эмульсии, содержащие свободное поверхностно-активное вещество в водной фазе в качестве адъюванта сплит вакцин против гриппа
PL2368572T3 (pl)	2005-11-04	2020-11-16	Seqirus UK Limited	Szczepionki z adjuwantem z niewirionowymi antygenami otrzymane z wirusów grypy hodowanych w hodowli komórkowej
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EP2478916B1 (de)	2006-01-27	2020-04-01	Seqirus UK Limited	Influenzaimpfstoffe mit Hämagglutinin und Matrixproteinen
JP2009534303A (ja)	2006-03-24	2009-09-24	ノバルティスヴァクシンズアンドダイアグノスティクスゲーエムベーハーアンドカンパニーカーゲー	冷蔵しないインフルエンザワクチンの保存
JP2009532352A (ja)	2006-03-31	2009-09-10	ダブリュエーアールエフ−ウィスコンシンアラムナイリサーチファウンデーション	ワクチンのための高力価組み換えインフルエンザ・ウィルス
WO2007146057A2 (en) *	2006-06-09	2007-12-21	Wisconsin Alumni Research Foundation	Screening method for modulators of viral transcription or replication
GB0614460D0 (en)	2006-07-20	2006-08-30	Novartis Ag	Vaccines
WO2008133701A1 (en)	2006-07-21	2008-11-06	Medimmune, Llc.	Methods and compositions for increasing replication capacity of an influenza virus
JP2010500034A (ja)	2006-08-09	2010-01-07	メッドイミューンバクシーンズ，インコーポレイティド	インフルエンザ赤血球凝集素変異体およびノイラミニダーゼ変異体
BRPI0716536A2 (pt)	2006-09-11	2013-09-24	Novartis Ag	produÇço de vacinas de vÍrus influenza, sem a utilizaÇço de ovos
EP2121011B1 (de)	2006-12-06	2014-05-21	Novartis AG	Impfstoffe mit antigen aus vier stämmen des influenzavirus
US8597661B2 (en)	2007-05-04	2013-12-03	Wisconsin Alumni Research Foundation	Neuraminidase-deficient live influenza vaccines
WO2008157583A1 (en)	2007-06-18	2008-12-24	Medimmune, Llc	Influenza b viruses having alterations in the hemaglutinin polypeptide
US9474798B2 (en)	2007-06-18	2016-10-25	Wisconsin Alumni Research Foundation	Influenza M2 protein mutant viruses as live influenza attenuated vaccines
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CA2752041A1 (en)	2009-02-10	2010-08-19	Novartis Ag	Influenza vaccines with increased amounts of h3 antigen
EA023662B1 (ru)	2009-02-10	2016-06-30	Новартис Аг	Вакцины против гриппа со сниженным количеством сквалена
KR20110132373A (ko)	2009-02-10	2011-12-07	노파르티스 아게	유행병-연관 주에 대한 인플루엔자 백신 요법
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2000
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Also Published As

Publication number	Publication date
DK1185615T3 (da)	2007-11-05
DE122008000061I1 (de)	2009-02-12
HK1148778A1 (zh)	2011-09-16
ES2533622T3 (es)	2015-04-13
NL300365I2 (nl)	2017-08-03
CA2365526C (en)	2016-07-05
DE122008000014I1 (de)	2011-12-01
CN101851636B (zh)	2015-11-25
WO2000060050A2 (en)	2000-10-12
CA2928263A1 (en)	2000-10-12
CY1108520T1 (el)	2014-04-09
HK1214298A1 (en)	2016-07-22
JP5543048B2 (ja)	2014-07-09
EP1820853A3 (de)	2007-10-03
JP6224645B2 (ja)	2017-11-01
NL300365I1 (nl)	2009-01-05
NL300364I1 (nl)	2009-01-05
EP1185615B1 (de)	2007-08-01
EP2345716A1 (de)	2011-07-20
JP2011182797A (ja)	2011-09-22
CY1112140T1 (el)	2015-11-04
ES2373405T3 (es)	2012-02-03
FR11C0027I2 (fr)	2021-12-31
IL145702A0 (en)	2002-07-25
WO2000060050A3 (en)	2001-01-18
MXPA01010082A (es)	2002-04-24
KR100702275B1 (ko)	2007-03-30
ES2290024T3 (es)	2008-02-16
DE60035778D1 (de)	2007-09-13
CN101851636A (zh)	2010-10-06
DK2345716T3 (en)	2015-02-09
BRPI0009580B8 (pt)	2021-05-25
AU4073300A (en)	2000-10-23
DK1820853T3 (da)	2011-12-19
EP1820853B1 (de)	2011-09-21
CN1350578A (zh)	2002-05-22
EP1185615A2 (de)	2002-03-13
BR0009580A (pt)	2002-01-02
JP2015119735A (ja)	2015-07-02
NL300364I2 (nl)	2017-08-03
EP2910629B1 (de)	2018-09-19
ATE525461T1 (de)	2011-10-15
PT1185615E (pt)	2007-10-04
DE122011100037I1 (de)	2012-03-22
JP2003528570A (ja)	2003-09-30
CA2365526A1 (en)	2000-10-12
DE60035778T2 (de)	2008-04-30
DE122008000058I1 (de)	2009-05-07
EP2910629A1 (de)	2015-08-26
ATE368729T1 (de)	2007-08-15
EP2345716B1 (de)	2015-01-14
BR0009580B1 (pt)	2014-11-25
IL145702A (en)	2010-04-15
FR11C0027I1 (fr)	2011-08-26
JP5775351B2 (ja)	2015-09-09
PT1820853E (pt)	2012-01-03
CN1350578B (zh)	2010-05-12
KR20010113044A (ko)	2001-12-24
EP1820853A2 (de)	2007-08-22

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