CY1120395T1 - Παραγωγα στερολης και χρηση αυτων για την αγωγη νοσηματων που περιλαμβανουν μετασχηματισμενα αστροκυτταρα ή για την αγωγη κακοηθων αιμοπαθειων - Google Patents
Παραγωγα στερολης και χρηση αυτων για την αγωγη νοσηματων που περιλαμβανουν μετασχηματισμενα αστροκυτταρα ή για την αγωγη κακοηθων αιμοπαθειωνInfo
- Publication number
- CY1120395T1 CY1120395T1 CY20181100306T CY181100306T CY1120395T1 CY 1120395 T1 CY1120395 T1 CY 1120395T1 CY 20181100306 T CY20181100306 T CY 20181100306T CY 181100306 T CY181100306 T CY 181100306T CY 1120395 T1 CY1120395 T1 CY 1120395T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- diseases
- sterolis
- concluding
- producers
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Η εφεύρεση αφορά νέα παράγωγα στερόλης, τη μέθοδο παρασκευής αυτών, φαρμακευτικές συνθέσεις οι οποίες περιέχουν αυτά και τη χρήση αυτών για την αγωγή νοσημάτων, στα οποία εμπλέκονται μετασχηματισμένα κύτταρα αστροκυτώματος ή για την αγωγή κακοηθών αιμοπαθειών. Η εφεύρεση συγκεκριμένα αφορά την αγωγή του πολύμορφου γλοιοβλαστώματος, όπως επίσης άλλων καρκίνων, όπως λεμφώματα, νευροβλαστώματα και μελανώματα.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12305518.8A EP2662382B1 (fr) | 2012-05-10 | 2012-05-10 | Dérivés de stérol, leur procédé de préparation, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement du glioblastome multiple |
| US201261656151P | 2012-06-06 | 2012-06-06 | |
| EP13729470.8A EP2847204B1 (en) | 2012-05-10 | 2013-05-07 | Sterol derivatives and use thereof for treating diseases involving transformed astrocyte cells or for treating malignant haemopathies |
| PCT/IB2013/053669 WO2013168096A1 (en) | 2012-05-10 | 2013-05-07 | Sterol derivatives and use thereof for treating diseases involving transformed astrocyte cells or for treating malignant haemopathies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1120395T1 true CY1120395T1 (el) | 2019-07-10 |
Family
ID=46149353
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20161100621T CY1117723T1 (el) | 2012-05-10 | 2016-07-05 | Παραγωγα στερολης, μεθοδος για την παρασκευη των ιδιων, φαρμακευτικες συνθεσεις οι οποιες περιεχουν τα ιδια και χρηση αυτων για την αγωγη πολλαπλων γλοιοβλαστωματων |
| CY20181100306T CY1120395T1 (el) | 2012-05-10 | 2018-03-13 | Παραγωγα στερολης και χρηση αυτων για την αγωγη νοσηματων που περιλαμβανουν μετασχηματισμενα αστροκυτταρα ή για την αγωγη κακοηθων αιμοπαθειων |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20161100621T CY1117723T1 (el) | 2012-05-10 | 2016-07-05 | Παραγωγα στερολης, μεθοδος για την παρασκευη των ιδιων, φαρμακευτικες συνθεσεις οι οποιες περιεχουν τα ιδια και χρηση αυτων για την αγωγη πολλαπλων γλοιοβλαστωματων |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US10800806B2 (el) |
| EP (2) | EP2662382B1 (el) |
| JP (1) | JP6270823B2 (el) |
| KR (1) | KR102160316B1 (el) |
| CN (1) | CN104302655B (el) |
| BR (1) | BR112014026948B1 (el) |
| CA (1) | CA2871714C (el) |
| CY (2) | CY1117723T1 (el) |
| DK (2) | DK2662382T3 (el) |
| ES (2) | ES2580331T3 (el) |
| HK (2) | HK1191654A1 (el) |
| HR (2) | HRP20160624T1 (el) |
| HU (2) | HUE029243T2 (el) |
| IN (1) | IN2014DN09437A (el) |
| LT (1) | LT2847204T (el) |
| ME (1) | ME02436B (el) |
| PL (2) | PL2662382T3 (el) |
| PT (2) | PT2662382T (el) |
| RS (2) | RS54926B1 (el) |
| RU (1) | RU2627710C2 (el) |
| SI (2) | SI2662382T1 (el) |
| SM (2) | SMT201800147T1 (el) |
| TR (1) | TR201802700T4 (el) |
| WO (1) | WO2013168096A1 (el) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3013048A1 (fr) * | 2013-11-12 | 2015-05-15 | Beta Innov | Derive de sterol, son procede de preparation, composition pharmaceutique le contenant et son utilisation pour le traitement du glioblastome multiforme |
| EP3593789A1 (fr) | 2018-07-11 | 2020-01-15 | Beta Innov | Composition contenant un dérivé de 7beta-hydroxycholestérol et un véhicule lipidique, et son utilisation dans le traitement de pathologies néoplasiques |
| KR102748745B1 (ko) * | 2021-05-18 | 2025-01-03 | 연세대학교 산학협력단 | 암의 예방, 개선 또는 치료용 조성물 |
| KR102689231B1 (ko) * | 2021-05-18 | 2024-07-30 | 연세대학교 산학협력단 | 암의 예방, 개선 또는 치료용 조성물 |
| WO2024030660A2 (en) * | 2022-08-04 | 2024-02-08 | University Of Massachusetts | Cholesterol-modified hyaluronic acids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9602100D0 (sv) * | 1996-05-30 | 1996-05-30 | Magnus Axelson | New pharmaceuticals |
| WO2004029068A1 (en) * | 2002-09-25 | 2004-04-08 | Forbes Medi-Tech Inc. | Derivatives comprising sterols and/or stanols and specific classes of anti-inflammatory agents and use thereof in treating or preventing cardiovascular disease |
-
2012
- 2012-05-10 HU HUE12305518A patent/HUE029243T2/en unknown
- 2012-05-10 ES ES12305518.8T patent/ES2580331T3/es active Active
- 2012-05-10 DK DK12305518.8T patent/DK2662382T3/en active
- 2012-05-10 EP EP12305518.8A patent/EP2662382B1/fr active Active
- 2012-05-10 ME MEP-2016-134A patent/ME02436B/me unknown
- 2012-05-10 SI SI201230585A patent/SI2662382T1/sl unknown
- 2012-05-10 PT PT123055188T patent/PT2662382T/pt unknown
- 2012-05-10 RS RS20160499A patent/RS54926B1/sr unknown
- 2012-05-10 PL PL12305518.8T patent/PL2662382T3/pl unknown
-
2013
- 2013-05-07 PL PL13729470T patent/PL2847204T3/pl unknown
- 2013-05-07 SM SM20180147T patent/SMT201800147T1/it unknown
- 2013-05-07 BR BR112014026948-3A patent/BR112014026948B1/pt active IP Right Grant
- 2013-05-07 PT PT137294708T patent/PT2847204T/pt unknown
- 2013-05-07 RU RU2014149705A patent/RU2627710C2/ru active
- 2013-05-07 ES ES13729470.8T patent/ES2662123T3/es active Active
- 2013-05-07 IN IN9437DEN2014 patent/IN2014DN09437A/en unknown
- 2013-05-07 RS RS20180237A patent/RS57065B1/sr unknown
- 2013-05-07 US US14/399,336 patent/US10800806B2/en active Active
- 2013-05-07 DK DK13729470.8T patent/DK2847204T3/en active
- 2013-05-07 WO PCT/IB2013/053669 patent/WO2013168096A1/en active Application Filing
- 2013-05-07 CA CA2871714A patent/CA2871714C/en active Active
- 2013-05-07 LT LTEP13729470.8T patent/LT2847204T/lt unknown
- 2013-05-07 JP JP2015510925A patent/JP6270823B2/ja active Active
- 2013-05-07 TR TR2018/02700T patent/TR201802700T4/tr unknown
- 2013-05-07 CN CN201380023824.4A patent/CN104302655B/zh active Active
- 2013-05-07 KR KR1020147034290A patent/KR102160316B1/ko active Active
- 2013-05-07 HU HUE13729470A patent/HUE037004T2/hu unknown
- 2013-05-07 SI SI201330962T patent/SI2847204T1/en unknown
- 2013-05-07 EP EP13729470.8A patent/EP2847204B1/en active Active
-
2014
- 2014-05-12 HK HK14104465.2A patent/HK1191654A1/zh unknown
-
2015
- 2015-08-17 HK HK15107906.1A patent/HK1207385A1/xx unknown
-
2016
- 2016-06-07 HR HRP20160624TT patent/HRP20160624T1/hr unknown
- 2016-07-05 SM SM201600215T patent/SMT201600215B/it unknown
- 2016-07-05 CY CY20161100621T patent/CY1117723T1/el unknown
-
2018
- 2018-02-26 HR HRP20180345TT patent/HRP20180345T1/hr unknown
- 2018-03-13 CY CY20181100306T patent/CY1120395T1/el unknown
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