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CY1119002T1 - Αναλογα πολυαιθερα δεσφεριθιοκινης - Google Patents

Αναλογα πολυαιθερα δεσφεριθιοκινης

Info

Publication number
CY1119002T1
CY1119002T1 CY20171100135T CY171100135T CY1119002T1 CY 1119002 T1 CY1119002 T1 CY 1119002T1 CY 20171100135 T CY20171100135 T CY 20171100135T CY 171100135 T CY171100135 T CY 171100135T CY 1119002 T1 CY1119002 T1 CY 1119002T1
Authority
CY
Cyprus
Prior art keywords
polyetherine
despherthiocin
answers
neoplastic
diseases
Prior art date
Application number
CY20171100135T
Other languages
English (en)
Inventor
Raymond J Bergeron
Original Assignee
University Of Florida Research Foundation, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36676582&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1119002(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University Of Florida Research Foundation, Inc. filed Critical University Of Florida Research Foundation, Inc.
Publication of CY1119002T1 publication Critical patent/CY1119002T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Οι ενώσεις που έχουν συντακτικούς τύπους που περιγράφονται στο παρόν, όπως ο Συντακτικός Τύπος (I): είναι χρήσιμες στη θεραπευτική αντιμετώπιση παθήσεων όπως η υπερφόρτωση μετάλλων, το οξειδωτικό στρες, και νεοπλασματικές και προ-νεοπλασματικές παθήσεις.
CY20171100135T 2005-04-04 2017-01-31 Αναλογα πολυαιθερα δεσφεριθιοκινης CY1119002T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66804505P 2005-04-04 2005-04-04
PCT/US2006/010945 WO2006107626A1 (en) 2005-04-04 2006-03-22 Desferrithiocin polyether analogues

Publications (1)

Publication Number Publication Date
CY1119002T1 true CY1119002T1 (el) 2018-01-10

Family

ID=36676582

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20171100135T CY1119002T1 (el) 2005-04-04 2017-01-31 Αναλογα πολυαιθερα δεσφεριθιοκινης

Country Status (14)

Country Link
US (6) US8278458B2 (el)
EP (2) EP3190106B1 (el)
JP (3) JP5202299B2 (el)
CN (1) CN101189216B (el)
AU (1) AU2006232929B9 (el)
BR (1) BRPI0610644B8 (el)
CA (1) CA2603385C (el)
CY (1) CY1119002T1 (el)
DK (2) DK1866296T3 (el)
ES (2) ES2732625T3 (el)
MX (1) MX2007012226A (el)
PL (2) PL1866296T3 (el)
TR (1) TR201910900T4 (el)
WO (1) WO2006107626A1 (el)

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* Cited by examiner, † Cited by third party
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WO2005034949A1 (en) 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
ES2732625T3 (es) 2005-04-04 2019-11-25 Univ Florida Análogos de poliéter de desferritiocina
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WO2008115433A1 (en) * 2007-03-15 2008-09-25 University Of Florida Desferrithiocin polyether analogues
NZ590302A (en) 2008-07-14 2013-02-22 Ferrokin Biosciences Inc Novel salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
US20110053993A1 (en) * 2009-07-27 2011-03-03 Ferrokin Biosciences, Inc. Prodrugs of desazadesferrothiocin polyether analogues as metal chelation agents
WO2011028255A2 (en) * 2009-08-25 2011-03-10 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues and uses thereof
NZ603774A (en) * 2010-05-04 2014-11-28 Ferrokin Biosciences Inc Desazadesferrothiocin analogues as metal chelation agents
CA2857990A1 (en) 2011-12-09 2013-06-13 Ferrokin Biosciences, Inc. Oral formulations for treating metal overload
EP2790697B1 (en) * 2011-12-16 2019-10-23 University of Florida Research Foundation, Inc. Uses of 4'-desferrithiocin analogs
JP2016513652A (ja) 2013-03-15 2016-05-16 フェロキン バイオサイエンシーズ， インコーポレイテッド デスアザデスフェリチオシン類似体の多形形態
CA2930966A1 (en) 2013-11-22 2015-05-28 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
CN106660270A (zh) * 2014-07-18 2017-05-10 应用材料公司 使用激光与等离子体的增材制造
CN107708693A (zh) * 2015-04-27 2018-02-16 佛罗里达大学研究基金会 代谢程序化的金属螯合剂及其用途
US10982136B2 (en) 2016-02-26 2021-04-20 The Regents Of The University Of California Ligand-sensitized lanthanide nanocrystals as ultraviolet downconverters
AU2017307566B2 (en) 2016-08-05 2023-06-15 Abfero Pharmaceuticals, Inc. Dosing regimens for treating metal-mediated conditions
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US11684614B2 (en) 2016-09-06 2023-06-27 The Regents Of The University Of California Formulations of hydroxypyridonate actinide/lanthanide decorporation agents
EP3520117B1 (en) 2016-09-29 2023-11-08 The Regents of The University of California Separation of metal ions by liquid-liquid extraction

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Also Published As

Publication number Publication date
AU2006232929B9 (en) 2009-12-17
ES2732625T3 (es) 2019-11-25
MX2007012226A (es) 2007-12-10
CN101189216B (zh) 2011-10-19
BRPI0610644A2 (pt) 2010-07-13
PL3190106T3 (pl) 2019-10-31
CN101189216A (zh) 2008-05-28
CA2603385C (en) 2014-07-15
US8722899B2 (en) 2014-05-13
JP2012131814A (ja) 2012-07-12
TR201910900T4 (tr) 2019-08-21
EP3190106B1 (en) 2019-05-08
JP2015145403A (ja) 2015-08-13
AU2006232929A1 (en) 2006-10-12
BRPI0610644B8 (pt) 2021-05-25
US9994535B2 (en) 2018-06-12
JP5202299B2 (ja) 2013-06-05
AU2006232929B2 (en) 2009-11-05
US20080214630A1 (en) 2008-09-04
US20180290990A1 (en) 2018-10-11
US9096553B2 (en) 2015-08-04
US20150336911A1 (en) 2015-11-26
US20140235680A1 (en) 2014-08-21
EP1866296A1 (en) 2007-12-19
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JP6178816B2 (ja) 2017-08-09
US9567309B2 (en) 2017-02-14
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JP2008536833A (ja) 2008-09-11
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PL1866296T3 (pl) 2017-05-31
WO2006107626A1 (en) 2006-10-12
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US20130030028A1 (en) 2013-01-31
US8278458B2 (en) 2012-10-02
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