CY1117317T1 - Αναστολεις κινασης janus για θεραπεια ξηροφθαλμιας και αλλων σχετικων με τον οφθαλμο ασθενειων - Google Patents
Αναστολεις κινασης janus για θεραπεια ξηροφθαλμιας και αλλων σχετικων με τον οφθαλμο ασθενειωνInfo
- Publication number
- CY1117317T1 CY1117317T1 CY20161100241T CY161100241T CY1117317T1 CY 1117317 T1 CY1117317 T1 CY 1117317T1 CY 20161100241 T CY20161100241 T CY 20161100241T CY 161100241 T CY161100241 T CY 161100241T CY 1117317 T1 CY1117317 T1 CY 1117317T1
- Authority
- CY
- Cyprus
- Prior art keywords
- disposals
- janus kinase
- disease diseases
- dry cottage
- dry
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Παρέχονται μέθοδοι, κιτ και συνθέσεις για θεραπεία διαταραχών ξηροφθαλμίας και άλλων σχετικών με τον οφθαλμό ασθενειών, όπου οι μέθοδοι, κιτ και συνθέσεις χρησιμοποιούν αναστολέα JAK.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10224208P | 2008-10-02 | 2008-10-02 | |
EP09737257.7A EP2349260B1 (en) | 2008-10-02 | 2009-10-01 | Janus kinase inhibitors for treatment of dry eye and other eye related diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1117317T1 true CY1117317T1 (el) | 2017-04-26 |
Family
ID=41572626
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20161100241T CY1117317T1 (el) | 2008-10-02 | 2016-03-22 | Αναστολεις κινασης janus για θεραπεια ξηροφθαλμιας και αλλων σχετικων με τον οφθαλμο ασθενειων |
Country Status (19)
Country | Link |
---|---|
US (4) | US20100113416A1 (el) |
EP (2) | EP2349260B1 (el) |
JP (5) | JP2012504639A (el) |
AR (2) | AR073530A1 (el) |
CA (2) | CA2738520C (el) |
CL (1) | CL2009001884A1 (el) |
CY (1) | CY1117317T1 (el) |
DK (1) | DK2349260T3 (el) |
ES (1) | ES2564203T3 (el) |
HK (1) | HK1160607A1 (el) |
HR (1) | HRP20160330T1 (el) |
HU (1) | HUE028499T2 (el) |
PL (1) | PL2349260T3 (el) |
PT (1) | PT2349260E (el) |
RS (1) | RS54651B1 (el) |
SI (1) | SI2349260T1 (el) |
SM (1) | SMT201600080B (el) |
TW (2) | TWI643622B (el) |
WO (1) | WO2010039939A1 (el) |
Families Citing this family (122)
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SG174026A1 (en) | 2006-08-03 | 2011-09-29 | Nitec Pharma Ag | Delayed-release glucocorticoid treatment of rheumatoid disease |
KR20090082507A (ko) | 2006-11-20 | 2009-07-30 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 통증 및 소양증 치료용 방법, 조성물 및 키트 |
UA99467C2 (xx) | 2007-06-13 | 2012-08-27 | Инсайт Корпорейшин | СОЛІ ІНГІБІТОРА ЯНУС-КІНАЗИ (R)-3-(4-(7H-ПІРОЛО$2,3-d]ПІРИМІДИН-4-ІЛ)-1H-ПІРАЗОЛ-1-ІЛ)-3-ЦИКЛОПЕНТИЛПРОПАННІТРИЛУ$СОЛИ ИНГИБИТОРА ЯНУС-КИНАЗЫ (R)-3-(4-(7H-ПИРРОЛО$2,3-d]ПИРИМИДИН-4-ИЛ)-1H-ПИРАЗОЛ-1-ИЛ)-3-ЦИКЛОПЕНТИЛПРОПАННИТРИЛА |
CL2008001709A1 (es) | 2007-06-13 | 2008-11-03 | Incyte Corp | Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras. |
WO2009064835A1 (en) * | 2007-11-16 | 2009-05-22 | Incyte Corporation | 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors |
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EP2391369A1 (en) * | 2009-01-26 | 2011-12-07 | Nitec Pharma AG | Delayed-release glucocorticoid treatment of asthma |
ME03556B (me) * | 2009-05-22 | 2020-07-20 | Incyte Holdings Corp | 3-[4-(7h-pirolo[2,3-d]pirimidin-4-il)-1 h-pirazol-1-il]oktan- ili нертan - niтril kао јак inhibiтori |
US8716303B2 (en) | 2009-05-22 | 2014-05-06 | Incyte Corporation | N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
WO2011006073A1 (en) | 2009-07-10 | 2011-01-13 | President And Fellows Of Harvard College | Permanently charged sodium and calcium channel blockers as anti-inflammatory agents |
US9249145B2 (en) | 2009-09-01 | 2016-02-02 | Incyte Holdings Corporation | Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
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- 2009-10-01 JP JP2011530218A patent/JP2012504639A/ja not_active Withdrawn
- 2009-10-01 EP EP09737257.7A patent/EP2349260B1/en active Active
- 2009-10-01 CA CA3064247A patent/CA3064247A1/en not_active Abandoned
- 2009-10-01 WO PCT/US2009/059203 patent/WO2010039939A1/en active Application Filing
- 2009-10-01 PT PT97372577T patent/PT2349260E/pt unknown
- 2009-10-01 SI SI200931388A patent/SI2349260T1/sl unknown
- 2009-10-01 TW TW106111786A patent/TWI643622B/zh active
- 2009-10-01 PL PL09737257T patent/PL2349260T3/pl unknown
- 2009-10-01 US US12/571,834 patent/US20100113416A1/en not_active Abandoned
- 2009-10-01 ES ES09737257.7T patent/ES2564203T3/es active Active
- 2009-10-01 DK DK09737257.7T patent/DK2349260T3/en active
- 2009-10-01 HU HUE09737257A patent/HUE028499T2/en unknown
- 2009-10-01 TW TW098133430A patent/TWI591068B/zh active
- 2009-10-01 EP EP15195683.6A patent/EP3042655A1/en not_active Withdrawn
- 2009-10-02 AR ARP090103822A patent/AR073530A1/es not_active Application Discontinuation
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2012
- 2012-02-02 HK HK12101002.0A patent/HK1160607A1/zh unknown
- 2012-08-01 US US13/564,271 patent/US20120301464A1/en not_active Abandoned
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2015
- 2015-03-04 JP JP2015042933A patent/JP2015127332A/ja active Pending
-
2016
- 2016-03-22 SM SM201600080T patent/SMT201600080B/it unknown
- 2016-03-22 CY CY20161100241T patent/CY1117317T1/el unknown
- 2016-04-01 HR HRP20160330TT patent/HRP20160330T1/hr unknown
- 2016-05-16 US US15/156,125 patent/US20170087158A1/en not_active Abandoned
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2017
- 2017-01-05 JP JP2017000685A patent/JP2017057231A/ja active Pending
- 2017-12-22 JP JP2017246134A patent/JP2018044012A/ja active Pending
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2018
- 2018-09-19 AR ARP180102672A patent/AR112822A2/es unknown
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2019
- 2019-11-18 US US16/686,934 patent/US20200093825A1/en not_active Abandoned
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2020
- 2020-01-09 JP JP2020002245A patent/JP2020050682A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PT2349260E (pt) | 2016-03-07 |
AR073530A1 (es) | 2010-11-10 |
JP2018044012A (ja) | 2018-03-22 |
US20100113416A1 (en) | 2010-05-06 |
JP2020050682A (ja) | 2020-04-02 |
HRP20160330T1 (hr) | 2016-05-06 |
CL2009001884A1 (es) | 2010-05-14 |
DK2349260T3 (en) | 2016-01-25 |
JP2017057231A (ja) | 2017-03-23 |
US20120301464A1 (en) | 2012-11-29 |
JP2012504639A (ja) | 2012-02-23 |
US20170087158A1 (en) | 2017-03-30 |
US20200093825A1 (en) | 2020-03-26 |
SI2349260T1 (sl) | 2016-05-31 |
TWI643622B (zh) | 2018-12-11 |
CA2738520A1 (en) | 2010-04-08 |
RS54651B1 (en) | 2016-08-31 |
ES2564203T3 (es) | 2016-03-18 |
PL2349260T3 (pl) | 2016-07-29 |
TWI591068B (zh) | 2017-07-11 |
CA3064247A1 (en) | 2010-04-08 |
TW201801731A (zh) | 2018-01-16 |
JP2015127332A (ja) | 2015-07-09 |
EP3042655A1 (en) | 2016-07-13 |
EP2349260B1 (en) | 2016-01-06 |
TW201018689A (en) | 2010-05-16 |
HK1160607A1 (zh) | 2012-08-10 |
WO2010039939A1 (en) | 2010-04-08 |
AR112822A2 (es) | 2019-12-18 |
HUE028499T2 (en) | 2016-12-28 |
CA2738520C (en) | 2020-03-10 |
SMT201600080B (it) | 2016-07-01 |
EP2349260A1 (en) | 2011-08-03 |
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