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CY1116278T1 - METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS - Google Patents

METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS

Info

Publication number
CY1116278T1
CY1116278T1 CY20151100245T CY151100245T CY1116278T1 CY 1116278 T1 CY1116278 T1 CY 1116278T1 CY 20151100245 T CY20151100245 T CY 20151100245T CY 151100245 T CY151100245 T CY 151100245T CY 1116278 T1 CY1116278 T1 CY 1116278T1
Authority
CY
Cyprus
Prior art keywords
caspase
aspartic
intermediates
suspensions
acute
Prior art date
Application number
CY20151100245T
Other languages
Greek (el)
Inventor
Gerald J Tanoury
Minzhang Chen
Andrew D Jones
Philip L Nyce
Martin Trudeau
David J Guerin
John R Snoonian
Original Assignee
Vertex Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP05728092.7A external-priority patent/EP1725548B1/en
Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of CY1116278T1 publication Critical patent/CY1116278T1/en

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η εφεύρεση αφορά σε μία μέθοδο παρασκευής μίας ένωσης που περιλαμβάνει καθαρισμό μίγματος, όπου R8 είναι προστατευτική ομάδα και ο καθαρισμός περιλαμβάνει χρωματογραφία, επιλεκτικώς κρυστάλλωση ή δυναμικώς κρυστάλλωση του μίγματος.The invention relates to a method of preparing a compound comprising purification of a mixture, wherein R8 is a protecting group and the purification comprises chromatography, selective crystallization or dynamically crystallization of the mixture.

CY20151100245T 2004-03-12 2015-03-12 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS CY1116278T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55248004A 2004-03-12 2004-03-12
EP05728092.7A EP1725548B1 (en) 2004-03-12 2005-03-11 Processes and intermediates for the preparation of aspartic acetal caspase inhibitors

Publications (1)

Publication Number Publication Date
CY1116278T1 true CY1116278T1 (en) 2017-02-08

Family

ID=58457916

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20151100232T CY1116276T1 (en) 2004-03-12 2015-03-06 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS
CY20151100244T CY1116277T1 (en) 2004-03-12 2015-03-12 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARATIC, ASPALO KASPAS
CY20151100245T CY1116278T1 (en) 2004-03-12 2015-03-12 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CY20151100232T CY1116276T1 (en) 2004-03-12 2015-03-06 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS
CY20151100244T CY1116277T1 (en) 2004-03-12 2015-03-12 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARATIC, ASPALO KASPAS

Country Status (1)

Country Link
CY (3) CY1116276T1 (en)

Also Published As

Publication number Publication date
CY1116276T1 (en) 2017-02-08
CY1116277T1 (en) 2017-02-08

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