[go: up one dir, main page]

CY1116276T1 - METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS - Google Patents

METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS

Info

Publication number
CY1116276T1
CY1116276T1 CY20151100232T CY151100232T CY1116276T1 CY 1116276 T1 CY1116276 T1 CY 1116276T1 CY 20151100232 T CY20151100232 T CY 20151100232T CY 151100232 T CY151100232 T CY 151100232T CY 1116276 T1 CY1116276 T1 CY 1116276T1
Authority
CY
Cyprus
Prior art keywords
caspase
aspartic
intermediates
suspensions
acute
Prior art date
Application number
CY20151100232T
Other languages
Greek (el)
Inventor
Gerald J Tanoury
Minzhang Chen
Andrew D Jones
Philip L Nyce
Martin Trudeau
David J Guerin
John R Snoonian
Original Assignee
Vertex Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP11178128.2A external-priority patent/EP2399916B1/en
Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of CY1116276T1 publication Critical patent/CY1116276T1/en

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η εφεύρεση αφορά σε μία μέθοδο παρασκευής μίας ένωσης που περιλαμβάνει καθαρισμό μίγματος, όπου R8 είναι προστατευτική ομάδα και ο καθαρισμός περιλαμβάνει χρωματογραφία, επιλεκτικώς κρυστάλλωση ή δυναμικώς κρυστάλλωση του μίγματος.The invention relates to a method of preparing a compound comprising purification of a mixture, wherein R8 is a protecting group and the purification comprises chromatography, selective crystallization or dynamically crystallization of the mixture.

CY20151100232T 2004-03-12 2015-03-06 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS CY1116276T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55248004A 2004-03-12 2004-03-12
EP11178128.2A EP2399916B1 (en) 2004-03-12 2005-03-11 Process and intermediates for the preparation of aspartic acetal caspase ihnhibitors

Publications (1)

Publication Number Publication Date
CY1116276T1 true CY1116276T1 (en) 2017-02-08

Family

ID=58457916

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20151100232T CY1116276T1 (en) 2004-03-12 2015-03-06 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS
CY20151100244T CY1116277T1 (en) 2004-03-12 2015-03-12 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARATIC, ASPALO KASPAS
CY20151100245T CY1116278T1 (en) 2004-03-12 2015-03-12 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS

Family Applications After (2)

Application Number Title Priority Date Filing Date
CY20151100244T CY1116277T1 (en) 2004-03-12 2015-03-12 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARATIC, ASPALO KASPAS
CY20151100245T CY1116278T1 (en) 2004-03-12 2015-03-12 METHOD AND INTERMEDIATES FOR THE PREPARATION OF ACUTE ASPARTIC, CASPASE SUSPENSIONS

Country Status (1)

Country Link
CY (3) CY1116276T1 (en)

Also Published As

Publication number Publication date
CY1116277T1 (en) 2017-02-08
CY1116278T1 (en) 2017-02-08

Similar Documents

Publication Publication Date Title
CY1113907T1 (en) Bicyclic heteroaryl compounds
CY1109998T1 (en) GLUTAMINIC RECEPTORS HARMONIZERS
EA200801560A1 (en) BIFENYL CARBOKSAMIDES
EA200501504A1 (en) Cannabinoid receptor ligands and their use
DK1601689T3 (en) Bacterial cytolysin purification procedure
DE60307775D1 (en) Filter Catalyst for the purification of exhaust gases
DE602006019964D1 (en) CLEANING OF MONTELUKAST
ECSP066436A (en) FUSIONED HETEROCICLIC COMPOUNDS
BRPI0510177B8 (en) compound, pharmaceutical composition and use thereof
EA200300566A1 (en) APPLICATION OF CCI-779 AS ANTI-TUMOR MEDIA
EA200702346A1 (en) CRYSTAL FORM OF 1-CHLOR-4- (β-D-GLUCOPIRANOZ-1-IL) -2- [4 - ((S) -TETRAHYDROFURAN-3-ILOXI) BENZIL] BENZENE, METHOD FOR ITS PREPARATION AND ITS APPLICATION FOR PREFERRED INDIVIDUAL REPRESENTS OF BENZOL] BENZOL
CR8226A (en) PROCESS FOR THE PREPARATION OF 4-AMINO-3-QUINOLINCARBONITRILOS
EP1412748A4 (en) MAGE-A3 PEPTIDES PRESENTED BY CLASS II HLA MOLECULES
DK1716119T3 (en) ANALOGS OF BENZOQUINON-CONTAINING ANAMICYCINES FOR TREATMENT OF CANCER
CR8437A (en) OXAZOL TETRACICLINE DERIVATIVES
CY1112888T1 (en) METHOD OF PREPARATION OF (S) -PANTOPRAZOL
IS8470A (en) Use of organic compounds
ATE496913T1 (en) NEW, LONG-ACTING BETAMIMETICS FOR THE TREATMENT OF RESPIRATORY DISEASES
DK1519944T3 (en) Methods for preparing fibrinogen
EA200600605A1 (en) REJUVENATED PENTANOLS, METHOD OF THEIR PRODUCTION AND THEIR APPLICATION AS ANTI-INFLAMMATORY MEANS
ECSP088151A (en) DIAZEPINOQUINOLINAS, SYNTHESIS OF THE SAME, AND INTERMEDIARIES TO OBTAIN THEM
DE60300548D1 (en) Catalyst for the purification of exhaust gases
DE602004012925D1 (en) Protocol for the provision of services
FI20030383A0 (en) Process for the preparation of the catalyst
DE602004004943D1 (en) Purification of metal hydrocarbon