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CY1108207T1 - Στοματικη παροχη φαρμακων - Google Patents

Στοματικη παροχη φαρμακων

Info

Publication number
CY1108207T1
CY1108207T1 CY20081100761T CY081100761T CY1108207T1 CY 1108207 T1 CY1108207 T1 CY 1108207T1 CY 20081100761 T CY20081100761 T CY 20081100761T CY 081100761 T CY081100761 T CY 081100761T CY 1108207 T1 CY1108207 T1 CY 1108207T1
Authority
CY
Cyprus
Prior art keywords
lozenge
medicines
oral delivery
stable
crystallising sugar
Prior art date
Application number
CY20081100761T
Other languages
English (en)
Inventor
Anders Dam
Janos Major
Peter Tasko
Original Assignee
Arrow No.7 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arrow No.7 Ltd filed Critical Arrow No.7 Ltd
Publication of CY1108207T1 publication Critical patent/CY1108207T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Παρέχεται μια παστίλια η οποία έχει ένα σταθερό pΗ και σταθερά επίπεδα δραστικού συστατικού κατά τη διάρκεια του χρόνου. Αυτή περιλαμβάνει ένα συνδυασμό από (i) τουλάχιστον ένα κόμμι και (ii) τουλάχιστον ένα σάκχαρο που δεν κρυσταλλώνεται ή μια αλκοόλη σακχάρου που δεν κρυσταλλώνεται σε μια μήτρα που προορίζεται για ελεγχόμενη στοματική παροχή ενός φαρμάκου. Η παστίλια περιέχει επίσης νερό και προαιρετικά συστατικά που επιλέγονται από αρωματικές ουσίες, παράγοντες που συγκαλύπτουν τη γεύση, χρωστικές ουσίες, συστατικά ρυθμιστικού διαλύματος, παράγοντες προσαρμογής pΗ, έκδοχα, σταθεροποιητές και γλυκαντικές ουσίες. Παρέχονται επίσης μέθοδοι για την παρασκευή της παστίλιας.
CY20081100761T 2003-09-05 2008-07-21 Στοματικη παροχη φαρμακων CY1108207T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0320854.3A GB0320854D0 (en) 2003-09-05 2003-09-05 Buccal drug delivery
GBGB0403373.4A GB0403373D0 (en) 2003-09-05 2004-02-16 Buccal drug delivery
EP04768358A EP1667662B1 (en) 2003-09-05 2004-09-06 Buccal drug delivery

Publications (1)

Publication Number Publication Date
CY1108207T1 true CY1108207T1 (el) 2014-02-12

Family

ID=34276828

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100761T CY1108207T1 (el) 2003-09-05 2008-07-21 Στοματικη παροχη φαρμακων

Country Status (22)

Country Link
US (4) US8343532B2 (el)
EP (2) EP1938806A1 (el)
JP (2) JP5303111B2 (el)
CN (1) CN1845724B (el)
AT (1) ATE392888T1 (el)
AU (1) AU2004269968B2 (el)
BR (1) BRPI0414178A (el)
CA (1) CA2537797C (el)
CY (1) CY1108207T1 (el)
DE (1) DE602004013348T2 (el)
DK (1) DK1667662T3 (el)
ES (1) ES2305842T3 (el)
GB (2) GB0320854D0 (el)
HR (1) HRP20080289T3 (el)
IL (1) IL173998A0 (el)
NO (1) NO20061525L (el)
NZ (1) NZ545673A (el)
PL (1) PL1667662T3 (el)
PT (1) PT1667662E (el)
SI (1) SI1667662T1 (el)
WO (1) WO2005023226A1 (el)
ZA (1) ZA200601902B (el)

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Also Published As

Publication number Publication date
SI1667662T1 (sl) 2008-10-31
PL1667662T3 (pl) 2008-10-31
US8603516B2 (en) 2013-12-10
ZA200601902B (en) 2007-09-26
EP1667662B1 (en) 2008-04-23
ES2305842T3 (es) 2008-11-01
CN1845724B (zh) 2015-05-13
US8343532B2 (en) 2013-01-01
GB0403373D0 (en) 2004-03-17
ATE392888T1 (de) 2008-05-15
DK1667662T3 (da) 2008-08-25
JP2013064005A (ja) 2013-04-11
US20130085165A1 (en) 2013-04-04
DE602004013348T2 (de) 2009-11-19
PT1667662E (pt) 2008-07-15
EP1938806A1 (en) 2008-07-02
JP5303111B2 (ja) 2013-10-02
US8858984B2 (en) 2014-10-14
DE602004013348D1 (de) 2008-06-05
JP2007504207A (ja) 2007-03-01
US20140054826A1 (en) 2014-02-27
US8603517B2 (en) 2013-12-10
CA2537797A1 (en) 2005-03-17
AU2004269968B2 (en) 2009-11-12
CA2537797C (en) 2011-10-25
HRP20080289T3 (en) 2008-08-31
BRPI0414178A (pt) 2006-10-31
NO20061525L (no) 2006-06-06
NZ545673A (en) 2009-03-31
US20070081949A1 (en) 2007-04-12
CN1845724A (zh) 2006-10-11
US20130087946A1 (en) 2013-04-11
EP1667662A1 (en) 2006-06-14
GB0320854D0 (en) 2003-10-08
WO2005023226A1 (en) 2005-03-17
AU2004269968A1 (en) 2005-03-17
IL173998A0 (en) 2006-07-05

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