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CY1107721T1 - Παραγωγα τυροζινης - Google Patents

Παραγωγα τυροζινης

Info

Publication number
CY1107721T1
CY1107721T1 CY20071101116T CY071101116T CY1107721T1 CY 1107721 T1 CY1107721 T1 CY 1107721T1 CY 20071101116 T CY20071101116 T CY 20071101116T CY 071101116 T CY071101116 T CY 071101116T CY 1107721 T1 CY1107721 T1 CY 1107721T1
Authority
CY
Cyprus
Prior art keywords
producers
tyrosine
alpha4
madcam
vcam
Prior art date
Application number
CY20071101116T
Other languages
English (en)
Inventor
David Y Jackson
Frederick C Sailes
Daniel P Sutherlin
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of CY1107721T1 publication Critical patent/CY1107721T1/el

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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    • C07C233/87—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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Abstract

Οι ενώσεις της εφεύρεσης είναι αναστολείς της άλφα4 οι οποίοι περιέχουν την μεσολαβούμενη από ιντεγκρίνη δέσμευση σε συνδέσμους όπως VCAM-1 και MAdCAM.
CY20071101116T 1999-09-24 2007-08-31 Παραγωγα τυροζινης CY1107721T1 (el)

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AU7613800A (en) 2001-04-24
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CA2385882A1 (en) 2001-03-29
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AU780385B2 (en) 2005-03-17
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IL148544A0 (en) 2002-09-12
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