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CY1107682T1 - Παραγωγα 4-τετραζολυλ-4 φαινυλπιπεριδινης για θεραπεια πονου - Google Patents

Παραγωγα 4-τετραζολυλ-4 φαινυλπιπεριδινης για θεραπεια πονου

Info

Publication number
CY1107682T1
CY1107682T1 CY20071100825T CY071100825T CY1107682T1 CY 1107682 T1 CY1107682 T1 CY 1107682T1 CY 20071100825 T CY20071100825 T CY 20071100825T CY 071100825 T CY071100825 T CY 071100825T CY 1107682 T1 CY1107682 T1 CY 1107682T1
Authority
CY
Cyprus
Prior art keywords
tetrazolyl
phenylperidine
production
phenylpiperidine
pain treatment
Prior art date
Application number
CY20071100825T
Other languages
English (en)
Inventor
Zhengming Chen
Original Assignee
Euro-Celtique S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro-Celtique S.A. filed Critical Euro-Celtique S.A.
Publication of CY1107682T1 publication Critical patent/CY1107682T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Αποκαλύπτονται ενώσεις 4-τετραζολυλ-4-φαινυλπιπεριδίνης, συνθέσεις, που περιλαμβάνουν αποτελεσματική ποσότητα μιας ένωσης 4-τετραζολυλ-4-φαινυλπιπεριδίνης, μέθοδοι για θεραπεία ή πρόληψη πόνου ή διάρροιας σε ένα ζώο, που περιλαμβάνουν χορήγηση σε ένα ζώο που έχει ανάγκη αυτής, μιας αποτελεσματικής ποσότητας μιας ένωσης 4-τετραζολυλ-4-φαινυλπιπεριδίνης και μεθόδοι για διέγερση λειτουργίας υποδοχέα οπιοειδούς σε ένα κύτταρο, που περιλαμβάνουν επαφή ενός κυττάρου ικανού έκφρασης ενός υποδοχέα οπιοειδούς με αποτελεσματική ποσότητα μιας ένωσης 4-τετραζολυλ-4-φαινυλπιπεριδίνης.
CY20071100825T 2002-11-18 2007-06-21 Παραγωγα 4-τετραζολυλ-4 φαινυλπιπεριδινης για θεραπεια πονου CY1107682T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42738102P 2002-11-18 2002-11-18
US46027803P 2003-04-03 2003-04-03
US48848803P 2003-07-17 2003-07-17
US10/714,066 US7202259B2 (en) 2002-11-18 2003-11-13 Therapeutic agents useful for treating pain
EP03789796A EP1562932B9 (en) 2002-11-18 2003-11-17 4-tetrazolyl-4-phenylpiperidine derivatives for treating pain

Publications (1)

Publication Number Publication Date
CY1107682T1 true CY1107682T1 (el) 2013-04-18

Family

ID=32777221

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20071100825T CY1107682T1 (el) 2002-11-18 2007-06-21 Παραγωγα 4-τετραζολυλ-4 φαινυλπιπεριδινης για θεραπεια πονου
CY20081101151T CY1108422T1 (el) 2002-11-18 2008-10-16 Παραγωγα 4-τετραζολυλ-4φαινυλπιπεριδινης για θεραπεια πονου

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY20081101151T CY1108422T1 (el) 2002-11-18 2008-10-16 Παραγωγα 4-τετραζολυλ-4φαινυλπιπεριδινης για θεραπεια πονου

Country Status (37)

Country Link
US (3) US7202259B2 (el)
EP (2) EP1562932B9 (el)
JP (2) JP4601429B2 (el)
KR (1) KR20050115221A (el)
CN (2) CN100567288C (el)
AP (1) AP2210A (el)
AR (1) AR047008A1 (el)
AT (2) ATE402167T1 (el)
AU (2) AU2003294313B2 (el)
BR (1) BR0316305A (el)
CA (1) CA2506242C (el)
CO (1) CO5690588A2 (el)
CR (2) CR7877A (el)
CY (2) CY1107682T1 (el)
DE (2) DE60313021T2 (el)
DK (2) DK1803718T3 (el)
EA (1) EA008621B1 (el)
EC (1) ECSP055840A (el)
ES (2) ES2312150T3 (el)
GE (1) GEP20084539B (el)
HK (1) HK1086829A1 (el)
IL (1) IL209352A0 (el)
IS (2) IS2720B (el)
MA (1) MA27565A1 (el)
ME (1) MEP48108A (el)
MX (1) MXPA05004669A (el)
MY (1) MY135647A (el)
NI (1) NI200500087A (el)
NO (1) NO20052894L (el)
NZ (2) NZ572685A (el)
OA (1) OA13010A (el)
PT (2) PT1803718E (el)
RS (1) RS51047B (el)
SG (1) SG165998A1 (el)
SI (2) SI1803718T1 (el)
TW (2) TW200819436A (el)
WO (1) WO2004046132A1 (el)

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Also Published As

Publication number Publication date
CA2506242C (en) 2011-07-05
AU2003294313B2 (en) 2010-08-26
EP1803718B1 (en) 2008-07-23
OA13010A (en) 2006-11-10
SI1803718T1 (sl) 2008-12-31
WO2004046132A1 (en) 2004-06-03
US20070179141A1 (en) 2007-08-02
PT1803718E (pt) 2008-09-26
TW200819436A (en) 2008-05-01
JP2010163452A (ja) 2010-07-29
JP2006525944A (ja) 2006-11-16
MEP48108A (en) 2011-02-10
AU2010246411A1 (en) 2010-12-16
AU2003294313A1 (en) 2004-06-15
US8026254B2 (en) 2011-09-27
CN101648941A (zh) 2010-02-17
RS51047B (sr) 2010-10-31
NO20052894D0 (no) 2005-06-14
SG165998A1 (en) 2010-11-29
CR7877A (es) 2005-11-30
CA2506242A1 (en) 2004-06-03
DK1803718T3 (da) 2008-10-27
JP4601429B2 (ja) 2010-12-22
NO20052894L (no) 2005-06-14
ATE358674T1 (de) 2007-04-15
TWI343917B (en) 2011-06-21
ECSP055840A (es) 2005-08-11
MA27565A1 (fr) 2005-10-03
BR0316305A (pt) 2005-09-27
EP1562932B1 (en) 2007-04-04
CR11037A (es) 2009-10-29
DK1562932T3 (da) 2007-08-13
DE60313021D1 (de) 2007-05-16
ES2285235T3 (es) 2007-11-16
GEP20084539B (en) 2008-11-25
AP2005003297A0 (en) 2005-06-30
MXPA05004669A (es) 2005-06-08
SI1562932T1 (sl) 2007-08-31
AP2210A (en) 2011-02-25
US7202259B2 (en) 2007-04-10
PT1562932E (pt) 2007-07-02
AR047008A1 (es) 2006-01-04
EA008621B1 (ru) 2007-06-29
EP1562932B9 (en) 2007-09-12
ES2312150T3 (es) 2009-02-16
CY1108422T1 (el) 2014-04-09
EP1803718A1 (en) 2007-07-04
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IS2720B (is) 2011-02-15
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US20100069437A1 (en) 2010-03-18
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US20040152689A1 (en) 2004-08-05
IL209352A0 (en) 2011-01-31
US7687518B2 (en) 2010-03-30
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MY135647A (en) 2008-06-30
HK1086829A1 (en) 2006-09-29
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EP1562932A1 (en) 2005-08-17
RS20050375A (en) 2007-11-15
TW200418828A (en) 2004-10-01
DE60313021T2 (de) 2007-12-13
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ATE402167T1 (de) 2008-08-15

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