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CY1106809T1 - Τριενυδρη αμοξικιλλινη - Google Patents

Τριενυδρη αμοξικιλλινη

Info

Publication number
CY1106809T1
CY1106809T1 CY20071101065T CY071101065T CY1106809T1 CY 1106809 T1 CY1106809 T1 CY 1106809T1 CY 20071101065 T CY20071101065 T CY 20071101065T CY 071101065 T CY071101065 T CY 071101065T CY 1106809 T1 CY1106809 T1 CY 1106809T1
Authority
CY
Cyprus
Prior art keywords
amoxicillin trihydrate
product
relates
preferably less
less
Prior art date
Application number
CY20071101065T
Other languages
English (en)
Inventor
Jan Willem Groenendaal
Everardus Johannus Anthonius Maria Leenderts
Van Der Thomas Does
Original Assignee
Dsm Ip Assets B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45007138&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1106809(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dsm Ip Assets B.V. filed Critical Dsm Ip Assets B.V.
Publication of CY1106809T1 publication Critical patent/CY1106809T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σ' ένα προϊόν τριένυδρης αμοξικιλλίνης, που έχει μία περιεκτικότητα ελεύθερου νερού λιγότερο από 0.1 wt.%, κατά προτίμηση λιγότερο από 0.07 wt.%, προτιμότερα λιγότερο από 0.05 wt.%, που μετρείται σε μία σχετική υγρασία ισορροπίας 30% και σε μία θερμοκρασία των 25°C. Το προϊόν χρησιμοποιείται ωφέλιμα ως μίγμα με κλαβουλανικό οξύ. Η εφεύρεση επίσης αναφέρεται σε μία διαδικασία για την παρασκευή του νέου προϊόντος.
CY20071101065T 2003-03-21 2007-08-09 Τριενυδρη αμοξικιλλινη CY1106809T1 (el)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US45618803P 2003-03-21 2003-03-21
US45618703P 2003-03-21 2003-03-21
EP03100732 2003-03-21
EP03100731 2003-03-21
EP04722271A EP1610766B1 (en) 2003-03-21 2004-03-22 Amoxicillin trihydrate
PCT/EP2004/003053 WO2004082663A1 (en) 2003-03-21 2004-03-22 Amoxicillin trihydrate

Publications (1)

Publication Number Publication Date
CY1106809T1 true CY1106809T1 (el) 2012-05-23

Family

ID=45007138

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071101065T CY1106809T1 (el) 2003-03-21 2007-08-09 Τριενυδρη αμοξικιλλινη

Country Status (14)

Country Link
US (1) US20060172987A1 (el)
EP (2) EP1610766B1 (el)
JP (2) JP4949827B2 (el)
CN (2) CN1761457B (el)
AT (1) ATE362359T1 (el)
BR (2) BRPI0408568A (el)
CY (1) CY1106809T1 (el)
DE (1) DE602004006507T2 (el)
ES (1) ES2286627T3 (el)
MX (2) MXPA05010104A (el)
PL (1) PL1610766T3 (el)
PT (1) PT1610766E (el)
SI (1) SI1610766T1 (el)
WO (3) WO2004082662A1 (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4949827B2 (ja) * 2003-03-21 2012-06-13 ディーエスエム アイピー アセッツ ビー．ブイ． アモキシシリン三水和物
US7534781B2 (en) * 2003-03-21 2009-05-19 Dsm Ip Assets B.V. Crystalline amoxicillin trihydrate powder
WO2008143239A1 (ja) * 2007-05-21 2008-11-27 Toray Industries, Inc. 結晶性微粉化粒子
US7985791B1 (en) 2008-02-22 2011-07-26 Lords Additives LLC Incorporation of SBP and ulexite into composites
EP2778171A1 (en) * 2013-03-15 2014-09-17 Synbias Pharma Ltd. Crystalline monohydrate of epirubicin hydrochloride
CN103145733B (zh) * 2013-03-20 2014-02-26 四川省惠达药业有限公司 一种阿莫西林化合物及该化合物和克拉维酸钾的药物组合物
CN111202713A (zh) * 2013-09-03 2020-05-29 灿盛制药有限公司荷兰公司 微粒化的阿莫西林
CN104059086B (zh) * 2014-06-19 2016-04-13 河南牧翔动物药业有限公司 一种阿莫西林晶体及其制备方法
CN104099396B (zh) * 2014-07-22 2016-03-23 石药集团中诺药业（石家庄）有限公司 一种直通法制备阿莫西林的工艺
WO2017186864A1 (en) 2016-04-27 2017-11-02 Sandoz Ag Enzymatic process for the production of beta-lactam antibiotics in the presence of particulate inoculum
CN109867687B (zh) * 2017-12-05 2021-08-17 上海朝瑞化工有限公司 一种高水溶性阿莫西林及其制备方法
CN111518119B (zh) * 2020-05-26 2021-12-21 联邦制药(内蒙古)有限公司 一种阿莫西林连续结晶工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532672A (en) * 1976-07-20 1978-11-15 Bristol Myers Co Process for the preparation of amoxicillin trihydrate
JPS5583789A (en) * 1978-12-18 1980-06-24 Bristol Myers Co Preparation of penicillin
JPS6052751B2 (ja) * 1981-04-21 1985-11-21 富山化学工業株式会社 新規な結晶形を有するセフアレキシン１水和物
WO1994017800A1 (en) * 1993-02-15 1994-08-18 Gist-Brocades B.V. AN IMPROVED β-LACTAM ANTIBIOTIC COMPOSITION
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
EP1023065A1 (en) * 1997-08-29 2000-08-02 Dsm N.V. Granules free of excipients
US20020137926A1 (en) * 1998-06-01 2002-09-26 Smithkline Beecham Corporation Process for preparing crystalline salts of amoxycillin
MXPA01009808A (es) * 1999-04-01 2002-04-24 Dsm Nv Aglomerados por cristalizacion.
AT412213B (de) * 2000-05-30 2004-11-25 Sandoz Ag Verfahren zur trocknung von amoxicillin oder amoxicillin-hältigen, oralen, festen pharmazeutischen zusammensetzungen unter verwendung eines gases mit einer definierten gasfeuchte
JP4949827B2 (ja) * 2003-03-21 2012-06-13 ディーエスエム アイピー アセッツ ビー．ブイ． アモキシシリン三水和物

Also Published As

Publication number Publication date
PL1610766T3 (pl) 2007-08-31
JP4949827B2 (ja) 2012-06-13
EP1610766A1 (en) 2006-01-04
CN102260278B (zh) 2015-05-06
CN1761457B (zh) 2010-05-12
MXPA05010102A (es) 2005-11-23
ATE362359T1 (de) 2007-06-15
PT1610766E (pt) 2007-08-01
DE602004006507T2 (de) 2008-01-31
CN102260278A (zh) 2011-11-30
WO2004082661A1 (en) 2004-09-30
US20060172987A1 (en) 2006-08-03
WO2004082663A1 (en) 2004-09-30
JP4949826B2 (ja) 2012-06-13
SI1610766T1 (sl) 2007-10-31
ES2286627T3 (es) 2007-12-01
DE602004006507D1 (en) 2007-06-28
WO2004082662A1 (en) 2004-09-30
BRPI0408568A (pt) 2006-03-21
MXPA05010104A (es) 2005-11-23
CN1761457A (zh) 2006-04-19
EP1808166A1 (en) 2007-07-18
JP2006523188A (ja) 2006-10-12
EP1610766B1 (en) 2007-05-16
JP2006520765A (ja) 2006-09-14
BRPI0408403A (pt) 2006-03-21

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