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CY1105225T1 - Παραγωγα 5-β-σαπωγενινης και ψευδοσαπωγενινης και η χρηση τους στην αντιμετωπιση ανοιας - Google Patents

Παραγωγα 5-β-σαπωγενινης και ψευδοσαπωγενινης και η χρηση τους στην αντιμετωπιση ανοιας

Info

Publication number
CY1105225T1
CY1105225T1 CY20061100986T CY061100986T CY1105225T1 CY 1105225 T1 CY1105225 T1 CY 1105225T1 CY 20061100986 T CY20061100986 T CY 20061100986T CY 061100986 T CY061100986 T CY 061100986T CY 1105225 T1 CY1105225 T1 CY 1105225T1
Authority
CY
Cyprus
Prior art keywords
treatment
sapogenin
dementia
derivatives
pseudosapogenin
Prior art date
Application number
CY20061100986T
Other languages
English (en)
Inventor
Paul Barraclough
Jim Hanson
Phil Gunning
Daryl Rees
Zongqin Xia
Yaer Hu
Original Assignee
Phytopharm Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phytopharm Plc filed Critical Phytopharm Plc
Publication of CY1105225T1 publication Critical patent/CY1105225T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η εφεύρεση γνωστοποιεί τη χρήση παραγώγων σαπωγενινών στην αντιμετώπιση διανοητικής δυσλειτουργίας και παρεμφερών καταστάσεων. Μέθοδοι αντιμετώπισης και φαρμακευτική σύνθεση γνωστοποιούνται επίσης.
CY20061100986T 1999-09-29 2006-07-17 Παραγωγα 5-β-σαπωγενινης και ψευδοσαπωγενινης και η χρηση τους στην αντιμετωπιση ανοιας CY1105225T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9923076.5A GB9923076D0 (en) 1999-09-29 1999-09-29 Sapogenin derivatives and their use
PCT/GB2000/003737 WO2001023406A1 (en) 1999-09-29 2000-09-29 5-beta-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia

Publications (1)

Publication Number Publication Date
CY1105225T1 true CY1105225T1 (el) 2010-03-03

Family

ID=10861837

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061100986T CY1105225T1 (el) 1999-09-29 2006-07-17 Παραγωγα 5-β-σαπωγενινης και ψευδοσαπωγενινης και η χρηση τους στην αντιμετωπιση ανοιας

Country Status (27)

Country Link
US (2) US7138427B2 (el)
EP (2) EP1724279A2 (el)
JP (1) JP2003510332A (el)
KR (1) KR100771491B1 (el)
CN (2) CN101411712A (el)
AT (1) ATE325808T1 (el)
AU (1) AU778294C (el)
BR (1) BR0014381A (el)
CA (2) CA2640998A1 (el)
CY (1) CY1105225T1 (el)
CZ (1) CZ300150B6 (el)
DE (1) DE60027913T2 (el)
DK (1) DK1224205T3 (el)
ES (1) ES2260055T3 (el)
GB (1) GB9923076D0 (el)
HK (1) HK1045525B (el)
HR (2) HRP20020255A2 (el)
IL (2) IL148920A0 (el)
MX (1) MXPA02003305A (el)
NO (1) NO324959B1 (el)
NZ (1) NZ518596A (el)
PT (1) PT1224205E (el)
RU (1) RU2325396C2 (el)
TR (1) TR200200821T2 (el)
UA (1) UA82978C2 (el)
WO (1) WO2001023406A1 (el)
ZA (1) ZA200202382B (el)

Families Citing this family (27)

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GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
GB0107822D0 (en) * 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use
PL213697B1 (pl) * 2002-03-27 2013-04-30 Phytopharm Plc Substancje czynne do stosowania w leczeniu chorób, zwlaszcza chorób neurodegeneracyjnych
BR0308788A (pt) * 2002-03-27 2005-01-11 Phytopharm Plc Processos terapêuticos e usos de sapogeninas e seus derivados
EP2111864A3 (en) * 2002-03-27 2009-12-30 Phytopharm Plc Therapeutic methods and uses of sapogenins and their derivatives
JP4607758B2 (ja) * 2002-10-28 2011-01-05 フィトファーム・パブリック・リミテッド・カンパニー サポゲン−３−オンの立体特異的還元
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GB0409567D0 (en) 2004-04-28 2004-06-02 Phytopharm Plc Chemical compounds
GB0424528D0 (en) 2004-11-05 2004-12-08 Phytopharm Plc Chemical compounds
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GB0513888D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
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CN101768202B (zh) * 2009-02-18 2013-10-30 沈阳药科大学 知母中菝葜皂苷元及其衍生物的制备方法及其医药新用途
CA2805693A1 (en) 2010-07-20 2012-01-26 Phytopharm Plc Treatment of l-dopa, dopamine agonist and/or dopamine enhancer induced disorders
CU20110244A7 (es) * 2011-12-27 2013-08-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem Sistemas espiroesteroidales con efectos neuroactivos y anti-inflamatorios
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CN102924559B (zh) * 2012-11-16 2015-10-28 沈阳药科大学 菝葜皂苷元衍生物及其制备和应用
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CN103232520A (zh) * 2013-05-13 2013-08-07 中国药科大学 一种螺甾类化合物、其制备方法及医药用途
CN104513289B (zh) * 2015-01-27 2017-12-22 华东理工大学 知母皂苷元结构修饰的衍生物、其药物组合物及其应用
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Also Published As

Publication number Publication date
DK1224205T3 (da) 2006-06-12
AU778294C (en) 2005-08-04
BR0014381A (pt) 2002-06-25
CN1377368A (zh) 2002-10-30
PT1224205E (pt) 2006-08-31
ATE325808T1 (de) 2006-06-15
KR100771491B1 (ko) 2007-10-30
GB9923076D0 (en) 1999-12-01
US7507720B2 (en) 2009-03-24
ES2260055T3 (es) 2006-11-01
CA2385402A1 (en) 2001-04-05
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MXPA02003305A (es) 2002-10-04
ZA200202382B (en) 2003-09-23
AU7537500A (en) 2001-04-30
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NO324959B1 (no) 2008-01-14
HK1045525A1 (en) 2002-11-29
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US20060100184A9 (en) 2006-05-11
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US20060276415A1 (en) 2006-12-07
US20030004147A1 (en) 2003-01-02
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UA82978C2 (ru) 2008-06-10
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US7138427B2 (en) 2006-11-21
RU2325396C2 (ru) 2008-05-27
EP1224205A1 (en) 2002-07-24
AU778294B2 (en) 2004-11-25
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NO20021541L (no) 2002-05-28

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