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BR0014355A - Derivados de sapogenina e seu uso no tratamento de disfunção cognitiva - Google Patents

Derivados de sapogenina e seu uso no tratamento de disfunção cognitiva

Info

Publication number
BR0014355A
BR0014355A BR0014355-3A BR0014355A BR0014355A BR 0014355 A BR0014355 A BR 0014355A BR 0014355 A BR0014355 A BR 0014355A BR 0014355 A BR0014355 A BR 0014355A
Authority
BR
Brazil
Prior art keywords
treatment
cognitive dysfunction
sapogenin derivatives
sapogenin
derivatives
Prior art date
Application number
BR0014355-3A
Other languages
English (en)
Inventor
Paul Barraclough
Jim Hanson
Phil Gunning
Daryl Rees
Zongqin Xia
Yaer Hu
Original Assignee
Phytopharm Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phytopharm Plc filed Critical Phytopharm Plc
Publication of BR0014355A publication Critical patent/BR0014355A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"DERIVADOS DE SAPOGENINA E SEU USO NO TRATAMENTO DE DISFUNçãO COGNITIVA". A invenção refere-se ao uso de derivados sapogenina no tratamento da disfunção cognitiva e condições similares. São também revelados métodos de tratamento e composições farmacêuticas.
BR0014355-3A 1999-09-29 2000-09-29 Derivados de sapogenina e seu uso no tratamento de disfunção cognitiva BR0014355A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9923077.3A GB9923077D0 (en) 1999-09-29 1999-09-29 Sapogenin derivatives and their use
PCT/GB2000/003745 WO2001023407A1 (en) 1999-09-29 2000-09-29 Sapogenin derivatives and their use in the treatment of cognitive dysfunction

Publications (1)

Publication Number Publication Date
BR0014355A true BR0014355A (pt) 2002-07-16

Family

ID=10861838

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0014355-3A BR0014355A (pt) 1999-09-29 2000-09-29 Derivados de sapogenina e seu uso no tratamento de disfunção cognitiva

Country Status (14)

Country Link
US (2) US20020183294A1 (pt)
EP (2) EP1224206B1 (pt)
JP (1) JP2003510333A (pt)
CN (2) CN1377367A (pt)
AT (1) ATE277072T1 (pt)
AU (1) AU7538200A (pt)
BR (1) BR0014355A (pt)
CA (1) CA2385410C (pt)
DE (1) DE60014136T2 (pt)
ES (1) ES2228608T3 (pt)
GB (1) GB9923077D0 (pt)
HK (1) HK1045526B (pt)
MX (1) MXPA02003306A (pt)
WO (1) WO2001023407A1 (pt)

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GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
BR0308788A (pt) * 2002-03-27 2005-01-11 Phytopharm Plc Processos terapêuticos e usos de sapogeninas e seus derivados
NZ563183A (en) * 2002-03-27 2009-03-31 Phytopharm Plc Therapeutic methods and uses of sapogenins and their derivatives
PL213697B1 (pl) * 2002-03-27 2013-04-30 Phytopharm Plc Substancje czynne do stosowania w leczeniu chorób, zwlaszcza chorób neurodegeneracyjnych
GB0329667D0 (en) * 2003-12-22 2004-01-28 King S College London Core 2 GlcNAc-T inhibitor
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US20080182801A1 (en) * 2003-12-22 2008-07-31 Btg International Limited Core 2 glcnac-t inhibitors
GB0409567D0 (en) 2004-04-28 2004-06-02 Phytopharm Plc Chemical compounds
GB0512726D0 (en) * 2005-06-22 2005-07-27 Btg Int Ltd Multiple sclerosis therapy and diagnosis
GB0513888D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
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AU2007352555B2 (en) 2006-11-20 2013-04-18 Satori Pharmaceuticals, Inc. Synthesis of compounds useful as modulators of amyloid-beta production
CN101610673A (zh) * 2006-11-20 2009-12-23 萨托里医药公司 可用于治疗神经变性紊乱的化合物
MX2011007842A (es) 2009-01-24 2012-01-12 Phytopharm Plc Tratamiento de trastornos mediados por factores neurotroficos.
PT2411028T (pt) * 2009-03-27 2019-08-30 Moleac Pte Ltd Terapia para promover o crescimento celular
EP2595621A1 (en) 2010-07-20 2013-05-29 Phytopharm PLC Treatment of l-dopa, dopamine agonist and/or dopamine enhancer induced disorders
CU20110244A7 (es) * 2011-12-27 2013-08-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem Sistemas espiroesteroidales con efectos neuroactivos y anti-inflamatorios
US11319338B2 (en) * 2012-04-03 2022-05-03 Goldporp Pharma Limited Timosaponin compounds
CN102924559B (zh) * 2012-11-16 2015-10-28 沈阳药科大学 菝葜皂苷元衍生物及其制备和应用
CN108264535A (zh) * 2016-12-30 2018-07-10 中国科学院上海药物研究所 一种抗抑郁化合物及其制备方法和应用

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Also Published As

Publication number Publication date
EP1224206B1 (en) 2004-09-22
EP1548025A2 (en) 2005-06-29
CA2385410C (en) 2008-05-20
EP1548025A3 (en) 2008-11-19
EP1224206A1 (en) 2002-07-24
MXPA02003306A (es) 2002-10-04
CA2385410A1 (en) 2001-04-05
GB9923077D0 (en) 1999-12-01
CN1377367A (zh) 2002-10-30
ATE277072T1 (de) 2004-10-15
WO2001023407A1 (en) 2001-04-05
DE60014136T2 (de) 2005-10-06
US20020183294A1 (en) 2002-12-05
HK1045526B (en) 2005-04-22
US20080021004A1 (en) 2008-01-24
DE60014136D1 (de) 2004-10-28
JP2003510333A (ja) 2003-03-18
CN101143147A (zh) 2008-03-19
ES2228608T3 (es) 2005-04-16
HK1045526A1 (en) 2002-11-29
AU7538200A (en) 2001-04-30

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]