CO6420374A2 - Efectos anti-perdida de hueso y pérdida de anti-adherimiento de una composición oral - Google Patents
Efectos anti-perdida de hueso y pérdida de anti-adherimiento de una composición oralInfo
- Publication number
- CO6420374A2 CO6420374A2 CO11114807A CO11114807A CO6420374A2 CO 6420374 A2 CO6420374 A2 CO 6420374A2 CO 11114807 A CO11114807 A CO 11114807A CO 11114807 A CO11114807 A CO 11114807A CO 6420374 A2 CO6420374 A2 CO 6420374A2
- Authority
- CO
- Colombia
- Prior art keywords
- loss
- test compound
- adhering
- bone
- effects
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56955—Bacteria involved in periodontal diseases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La presente invención divulga un método para determinar la utilidad de varios compuestos en el tratamiento de enfermedades y condiciones de la cavidad oral. En una realización, el método comprende contactar una célula con un compuesto de prueba, y determinar si el compuesto de prueba regula decrecientemente al menos una metaloproteinasa de la matriz seleccionada a partir de MMP-9 y MMP-13, en donde la regulación decreciente de la menos una de las metaloproteinasas de matriz, es una indicación que el compuesto de prueba es útil para tratar la periodontitis. La invención resulta particularmente útil en el campo de composiciones orales y de identificación de compuestos útiles en las mismas, a través de sus propiedades químicas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16568509P | 2009-04-01 | 2009-04-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6420374A2 true CO6420374A2 (es) | 2012-04-16 |
Family
ID=42328354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO11114807A CO6420374A2 (es) | 2009-04-01 | 2011-09-06 | Efectos anti-perdida de hueso y pérdida de anti-adherimiento de una composición oral |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8637266B2 (es) |
| EP (1) | EP2414838B1 (es) |
| JP (1) | JP5330596B2 (es) |
| CN (1) | CN102365550B (es) |
| AR (1) | AR076177A1 (es) |
| AU (1) | AU2010232590B2 (es) |
| BR (1) | BRPI1013185A2 (es) |
| CA (1) | CA2757317C (es) |
| CO (1) | CO6420374A2 (es) |
| DK (1) | DK2414838T3 (es) |
| ES (1) | ES2432864T3 (es) |
| HK (1) | HK1167272A1 (es) |
| MX (1) | MX2011008438A (es) |
| MY (1) | MY158406A (es) |
| PL (1) | PL2414838T3 (es) |
| RU (1) | RU2524629C2 (es) |
| SG (1) | SG173487A1 (es) |
| TW (1) | TWI405565B (es) |
| WO (1) | WO2010115031A1 (es) |
| ZA (1) | ZA201106054B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101745067B1 (ko) * | 2014-12-31 | 2017-06-12 | 서울대학교산학협력단 | 치주질환 예측 시스템 및 이를 이용한 치주질환 예측 방법 |
| KR102098624B1 (ko) * | 2019-09-20 | 2020-04-08 | 서울대학교산학협력단 | 타액 mmp-9 및 il-8를 이용한 치주염 예측 시스템 및 이를 이용한 치주염 예측 방법 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3538230A (en) | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
| US4358437A (en) | 1978-11-29 | 1982-11-09 | Beecham Group Limited | Compositions |
| US4894220A (en) | 1987-01-30 | 1990-01-16 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition |
| US5288480A (en) | 1987-01-30 | 1994-02-22 | Colgate-Palmolive Co. | Antiplaque antibacterial oral composition |
| US5032386A (en) | 1988-12-29 | 1991-07-16 | Colgate-Palmolive Company | Antiplaque antibacterial oral composition |
| GB9117140D0 (en) | 1991-08-08 | 1991-09-25 | Unilever Plc | Treatment of periodontitis |
| DE4226043A1 (de) | 1992-08-06 | 1994-02-10 | Haarmann & Reimer Gmbh | Mittel mit physiologischem Kühleffekt und für diese Mittel geeignete wirksame Verbindungen |
| US5756361A (en) * | 1992-12-17 | 1998-05-26 | Metra Biosystems, Inc. | Screening method for periodontal disease |
| US5840302A (en) | 1993-11-10 | 1998-11-24 | Bristol-Myers Squibb Company | Treatment of bacterially-induced inflammatory diseases |
| FI98961C (fi) * | 1994-08-26 | 1997-09-10 | Medix Biochemica Ab Oy | Menetelmät ja määritysvälineet parodontaalisairauden aktiivisuuden ja/tai peri-implantiitin ja/tai niiden kohonneen riskin diagnosoimiseksi |
| US5578295A (en) | 1995-04-28 | 1996-11-26 | The Procter & Gamble Company | Oral care compositions comprising certain substituted diphenyl ethers |
| WO1997047282A1 (de) | 1996-06-12 | 1997-12-18 | Henkel Kommanditgesellschaft Auf Aktien | Kosmetische und/oder pharmazeutische zubereitungen |
| US5998487A (en) * | 1998-04-08 | 1999-12-07 | Colgate-Palmolive Company | Anti-inflammatory and antibacterial benzyl phenol agents and their use in oral compositions |
| JP3763075B2 (ja) * | 1998-04-24 | 2006-04-05 | サンスター株式会社 | 歯周病の予防又は治療用の食品組成物、口腔用組成物及び医薬組成物 |
| FR2794457B1 (fr) | 1999-06-01 | 2001-08-10 | Oreal | Derives carbonates de retinol, procede de preparation et utilisations |
| US6165447A (en) * | 1999-06-15 | 2000-12-26 | Colgate-Palmolive Company | Synergistic antibacterial combination |
| EP2295968B1 (en) | 1999-12-03 | 2012-09-19 | Baxter International Inc. | Pyrogenicity test for use with automated immunoassay systems |
| GB0001704D0 (en) | 2000-01-25 | 2000-03-15 | Glaxo Group Ltd | Protein |
| US7329489B2 (en) | 2000-04-14 | 2008-02-12 | Matabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| EP1285092A4 (en) | 2000-04-14 | 2003-07-16 | Metabolon Inc | METHOD FOR DISCOVERY OF MEDICINES, DISEASE TREATMENT AND DIAGNOSIS USE THE METABOLOMICS |
| US6500409B1 (en) | 2000-05-10 | 2002-12-31 | Colgate Palmolive Company | Synergistic antiplaque/antigingivitis oral composition |
| DE10059584A1 (de) | 2000-11-30 | 2002-06-06 | Beiersdorf Ag | Kosmetische oder dermatologische getränkte Tücher |
| DOP2002000332A (es) * | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
| MXPA05001786A (es) * | 2002-08-13 | 2005-04-25 | Warner Lambert Co | Derivados de azaisoquinolina como inhibidores de la metaloproteinasa de matriz. |
| US7005225B2 (en) | 2002-11-12 | 2006-02-28 | Samsung Electronics Company | Organosol including amphipathic copolymeric binder having crystalline material, and use of the organosol to make dry tones for electrographic applications |
| PL378108A1 (pl) | 2003-02-14 | 2006-03-06 | Combinatorx, Incorporated | Leczenie łączone do terapii zapalnych zaburzeń immunologicznych |
| GB2401865A (en) | 2003-05-22 | 2004-11-24 | Givaudan Sa | Antibacterial and antifungal glycerol monocarbonates |
| EP1697389A4 (en) | 2003-10-24 | 2008-12-24 | Eisai R&D Man Co Ltd | COMPOUNDS AND METHODS FOR TREATING ILLNESS AND SUFFERING TOLL-LIKE RECEPTOR 2 RELATED DISORDERS |
| JP2007519894A (ja) | 2003-12-03 | 2007-07-19 | ホワイトヘッド インスティテュート フォー バイオメディカル リサーチ | 標的としてのカドヘリンの使用 |
| FI20040572A0 (fi) * | 2004-04-23 | 2004-04-23 | Ctt Cancer Targeting Tech Oy | Matriisi-metalloproteinaasin aktiviteetin inhibiittorit |
| JP4662043B2 (ja) * | 2004-09-09 | 2011-03-30 | 国立大学法人東京農工大学 | 歯周病発症の評価システム |
| CN101111288A (zh) * | 2004-12-02 | 2008-01-23 | 高露洁-棕榄公司 | 含酚类化合物和抗氧化剂维生素和维生素衍生物的口腔护理组合物 |
| US20060141421A1 (en) | 2004-12-28 | 2006-06-29 | Kimberly-Clark Worldwide, Inc. | System and method for detecting substances related to oral health |
| WO2006074450A2 (en) | 2005-01-07 | 2006-07-13 | President And Fellows Of Harvard College | Methods and compositions for detecting and modulating periodontal disorders and periodontal diseases |
| JP5024506B2 (ja) * | 2005-03-25 | 2012-09-12 | ライオン株式会社 | 歯周組織破壊の抑制・改善剤及び口腔用組成物 |
| CA2849559A1 (en) | 2006-01-10 | 2007-07-19 | Colgate-Palmolive Company | Methods of modulating cell surface receptors to prevent or reduce inflammation |
| US20080161394A1 (en) | 2006-11-23 | 2008-07-03 | Jean-Yves Fouron | Cosmetic composition comprising at least one volatile carbonic acid ester |
| WO2008093072A2 (en) | 2007-01-29 | 2008-08-07 | Paul Webb | Topical composition against contact dermatitis due to water |
| WO2009048841A1 (en) | 2007-10-09 | 2009-04-16 | Humco Holding Group, Inc. | Antifungal treatment of nails |
| TWI481870B (zh) * | 2009-04-01 | 2015-04-21 | Colgate Palmolive Co | 用於軟組織疾病診斷及作為用於口腔保健干預的標靶之蛋白質生物標記 |
-
2010
- 2010-03-31 TW TW099109773A patent/TWI405565B/zh not_active IP Right Cessation
- 2010-03-31 AR ARP100101094A patent/AR076177A1/es unknown
- 2010-04-01 BR BRPI1013185A patent/BRPI1013185A2/pt not_active IP Right Cessation
- 2010-04-01 CN CN201080015649.0A patent/CN102365550B/zh not_active Expired - Fee Related
- 2010-04-01 WO PCT/US2010/029670 patent/WO2010115031A1/en active Application Filing
- 2010-04-01 RU RU2011144028/15A patent/RU2524629C2/ru not_active IP Right Cessation
- 2010-04-01 CA CA2757317A patent/CA2757317C/en not_active Expired - Fee Related
- 2010-04-01 MX MX2011008438A patent/MX2011008438A/es active IP Right Grant
- 2010-04-01 PL PL10712854T patent/PL2414838T3/pl unknown
- 2010-04-01 SG SG2011055332A patent/SG173487A1/en unknown
- 2010-04-01 MY MYPI2011003577A patent/MY158406A/en unknown
- 2010-04-01 AU AU2010232590A patent/AU2010232590B2/en not_active Ceased
- 2010-04-01 ES ES10712854T patent/ES2432864T3/es active Active
- 2010-04-01 JP JP2012503715A patent/JP5330596B2/ja not_active Expired - Fee Related
- 2010-04-01 EP EP10712854.8A patent/EP2414838B1/en not_active Revoked
- 2010-04-01 US US13/262,027 patent/US8637266B2/en active Active
- 2010-04-01 DK DK10712854.8T patent/DK2414838T3/da active
-
2011
- 2011-08-17 ZA ZA2011/06054A patent/ZA201106054B/en unknown
- 2011-09-06 CO CO11114807A patent/CO6420374A2/es not_active Application Discontinuation
-
2012
- 2012-08-03 HK HK12107648.7A patent/HK1167272A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010232590A1 (en) | 2011-08-18 |
| AU2010232590B2 (en) | 2013-03-07 |
| ES2432864T3 (es) | 2013-12-05 |
| CN102365550B (zh) | 2014-08-13 |
| WO2010115031A1 (en) | 2010-10-07 |
| TWI405565B (zh) | 2013-08-21 |
| JP5330596B2 (ja) | 2013-10-30 |
| EP2414838A1 (en) | 2012-02-08 |
| PL2414838T3 (pl) | 2014-01-31 |
| AR076177A1 (es) | 2011-05-26 |
| MY158406A (en) | 2016-10-14 |
| DK2414838T3 (da) | 2013-11-04 |
| HK1167272A1 (en) | 2012-11-23 |
| EP2414838B1 (en) | 2013-08-28 |
| US20120107843A1 (en) | 2012-05-03 |
| CA2757317A1 (en) | 2010-10-07 |
| CA2757317C (en) | 2014-03-11 |
| TW201039812A (en) | 2010-11-16 |
| MX2011008438A (es) | 2011-09-06 |
| JP2012524884A (ja) | 2012-10-18 |
| RU2011144028A (ru) | 2013-05-10 |
| CN102365550A (zh) | 2012-02-29 |
| US8637266B2 (en) | 2014-01-28 |
| RU2524629C2 (ru) | 2014-07-27 |
| SG173487A1 (en) | 2011-09-29 |
| BRPI1013185A2 (pt) | 2016-04-12 |
| ZA201106054B (en) | 2014-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |