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CO5200778A1 - Composicion farmaceutica que comprende una cantidad terapeuticamente efectiva de b enzimidazol, administrada para prevenir y tratar el cancer e inhibir la metastasis - Google Patents

Composicion farmaceutica que comprende una cantidad terapeuticamente efectiva de b enzimidazol, administrada para prevenir y tratar el cancer e inhibir la metastasis

Info

Publication number
CO5200778A1
CO5200778A1 CO00060242A CO00060242A CO5200778A1 CO 5200778 A1 CO5200778 A1 CO 5200778A1 CO 00060242 A CO00060242 A CO 00060242A CO 00060242 A CO00060242 A CO 00060242A CO 5200778 A1 CO5200778 A1 CO 5200778A1
Authority
CO
Colombia
Prior art keywords
sub
carbon atoms
less
pharmaceutical composition
effective amount
Prior art date
Application number
CO00060242A
Other languages
English (en)
Inventor
Camden James Berger
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of CO5200778A1 publication Critical patent/CO5200778A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

La presente invención se refiere a una composición farmacéutica usada para prevenir el cáncer o inhibir la metástasis de cáncer en un paciente en riesgo donde la composición farmacéutica comprende una cantidad terapéuticamente efectiva de benzimidazol que tiene la fórmula:<EMI FILE="00060242_1" ID="1" IMF=JPEG >en donde X es hidrógeno, halógeno, alquilo inferior a 7 átomos de carbono o alcoxi inferior a 7 átomos de carbono; n es un número entero positivo inferior a 4; Y es hidrógeno, cloro, nitro, oxicloro, metilo o etilo; y R es hidrógeno o un grupo alquilo que tiene de 1 a 8 átomos de carbono, yR2 es NHCOOR1 en donde R1 es hidrocarburo alifático inferior a 7 átomos de carbono o las sales de adición ácidas o inorgánicas farmacéuticamente aceptable de éstos.
CO00060242A 1999-08-13 2000-08-11 Composicion farmaceutica que comprende una cantidad terapeuticamente efectiva de b enzimidazol, administrada para prevenir y tratar el cancer e inhibir la metastasis CO5200778A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/374,717 US6423734B1 (en) 1999-08-13 1999-08-13 Method of preventing cancer

Publications (1)

Publication Number Publication Date
CO5200778A1 true CO5200778A1 (es) 2002-09-27

Family

ID=23477934

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00060242A CO5200778A1 (es) 1999-08-13 2000-08-11 Composicion farmaceutica que comprende una cantidad terapeuticamente efectiva de b enzimidazol, administrada para prevenir y tratar el cancer e inhibir la metastasis

Country Status (12)

Country Link
US (2) US6423734B1 (es)
EP (1) EP1202735B1 (es)
JP (1) JP2003506482A (es)
AT (1) ATE279192T1 (es)
AU (1) AU763311B2 (es)
CA (1) CA2380414C (es)
CO (1) CO5200778A1 (es)
DE (1) DE60014916T2 (es)
MX (1) MXPA02001571A (es)
NZ (1) NZ516766A (es)
PE (1) PE20010541A1 (es)
WO (1) WO2001012169A2 (es)

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Also Published As

Publication number Publication date
JP2003506482A (ja) 2003-02-18
US6423734B1 (en) 2002-07-23
US6906091B2 (en) 2005-06-14
WO2001012169A3 (en) 2002-02-14
EP1202735A2 (en) 2002-05-08
MXPA02001571A (es) 2003-10-14
AU763311B2 (en) 2003-07-17
DE60014916D1 (de) 2004-11-18
US20030032664A1 (en) 2003-02-13
PE20010541A1 (es) 2001-05-16
CA2380414A1 (en) 2001-02-22
ATE279192T1 (de) 2004-10-15
DE60014916T2 (de) 2005-04-07
WO2001012169A2 (en) 2001-02-22
CA2380414C (en) 2006-06-13
EP1202735B1 (en) 2004-10-13
AU6521000A (en) 2001-03-13
NZ516766A (en) 2003-11-28

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