CN220584235U - Fecal transferrin detection kit integrating sample collection and detection - Google Patents
Fecal transferrin detection kit integrating sample collection and detection Download PDFInfo
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- CN220584235U CN220584235U CN202322217195.2U CN202322217195U CN220584235U CN 220584235 U CN220584235 U CN 220584235U CN 202322217195 U CN202322217195 U CN 202322217195U CN 220584235 U CN220584235 U CN 220584235U
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- 238000001514 detection method Methods 0.000 title claims abstract description 107
- 102000004338 Transferrin Human genes 0.000 title claims abstract description 28
- 108090000901 Transferrin Proteins 0.000 title claims abstract description 28
- 239000012581 transferrin Substances 0.000 title claims abstract description 28
- 230000002550 fecal effect Effects 0.000 title claims description 40
- 238000007789 sealing Methods 0.000 claims abstract description 71
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 31
- 239000007787 solid Substances 0.000 claims abstract description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 22
- 210000002700 urine Anatomy 0.000 claims abstract description 17
- 239000007788 liquid Substances 0.000 claims description 21
- 238000006243 chemical reaction Methods 0.000 claims description 12
- 238000004321 preservation Methods 0.000 claims description 12
- 238000010521 absorption reaction Methods 0.000 claims description 8
- 239000012530 fluid Substances 0.000 claims description 7
- 239000012535 impurity Substances 0.000 claims description 6
- 239000012528 membrane Substances 0.000 claims description 6
- 230000001681 protective effect Effects 0.000 claims description 5
- 238000007781 pre-processing Methods 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 3
- 239000012780 transparent material Substances 0.000 claims description 3
- 238000003149 assay kit Methods 0.000 claims 9
- 238000005192 partition Methods 0.000 claims 1
- 230000004927 fusion Effects 0.000 abstract description 5
- 239000000523 sample Substances 0.000 description 108
- 238000000034 method Methods 0.000 description 6
- 238000004587 chromatography analysis Methods 0.000 description 4
- 238000003908 quality control method Methods 0.000 description 4
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 239000000020 Nitrocellulose Substances 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229920001220 nitrocellulos Polymers 0.000 description 2
- 239000010902 straw Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000013100 final test Methods 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920006267 polyester film Polymers 0.000 description 1
- 239000012723 sample buffer Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
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Abstract
The application relates to a sample collection and detect integrative excrement and urine transferrin detect reagent box relates to the technical field that excrement and urine transferrin detected, including the collection subassembly that gathers the excrement and urine sample, the processing module that handles the sample of collection subassembly collection, the detection module that detects the sample after handling the processing module. According to the bottle cap, the bottle cap is taken out from the bottle body, and any one of solid, semi-solid and water sample states is collected through the collecting assembly; after collection, the sample is placed into the bottle body and sealed through the bottle cap, then the sample is shaken to be fully fused with the treatment, the limiting block is taken out after the fusion is completed, the bottle cap is screwed to enable the collection tube to puncture the sealing film, the pretreated solution enters the storage cavity and finally enters the detection cavity, the pretreated sample is contacted with the reagent strip and is detected, and therefore collection of samples in various forms is facilitated, pretreatment and detection of the samples are simplified.
Description
Technical Field
The application relates to the technical field of fecal transferrin detection, in particular to a fecal transferrin detection kit integrating sample collection and detection.
Background
The stool sample chromatographic detection kit is widely applied to field detection due to the advantages of rapidness, accuracy, trace and portability, and a user can quickly take effective countermeasures through results, so that more losses are avoided.
The existing fecal chromatographic kit is mainly used in the following methods: firstly, a sample collection and treatment bottle is used for collecting and pre-treating a fecal sample, and then the pretreated sample treatment liquid is transferred into a chromatographic detection kit for detection, and the detection result is read.
When the number of the detected samples is too large, the process is complicated, the samples are easily confused, and the samples can be added wrongly, missed and added multiply, so that the wrong detection result is finally obtained. And the collection device attached to the sample collection and treatment bottle is of a spoon-shaped or rod-shaped structure, so that the solid or semi-solid excrement is directly treated, when the collected object is a water sample, tools such as a straw are needed to be additionally used for collection, and if the tools such as the straw are not used on site, the sampling is difficult. How to accurately detect a sample when the detection sample is too much, and can include all forms of the fecal sample without other collection tools, is a problem to be solved.
Disclosure of Invention
In order to facilitate collection of samples in various forms and simplify pretreatment and detection of the samples, the application provides a fecal transferrin detection kit integrating sample collection and detection.
The application provides a sample collection and integrative excrement and urine transferrin detection kit that detects adopts following technical scheme:
the utility model provides a sample collection and detect integrative excrement and urine transferrin detect kit, includes the collection subassembly that gathers the excrement and urine sample, right the processing module that the sample that the collection subassembly gathered handled, right the detection module that the sample detected after the processing module handled, processing module and detection module are interconnect and mutually independent, collection subassembly and processing module and detection module are detachable connection.
Through adopting above-mentioned technical scheme, collection subassembly is used for gathering the excrement and urine sample of multiple form, then in putting into processing module with the sample after gathering, collection subassembly is sealed processing module simultaneously, and the sample after the preliminary treatment is discharged in the detection module at last and is detected to this is convenient for gather the sample of multiple form and simplify carrying out preliminary treatment and detection to the sample.
Further, the acquisition assembly includes:
the collecting pipe is of a cavity structure, the lower end of the collecting pipe is provided with a collecting part for collecting solid or semi-solid fecal samples, and the collecting part is of an arc-shaped strainer;
the bottle cap is of a cylindrical structure, the collecting pipe is fixedly arranged on the end face of the bottle cap, an external thread which is convenient to connect with the processing assembly is arranged on the bottle cap, and a protecting shell which is convenient for a user to take is arranged on the bottle cap.
Through adopting above-mentioned technical scheme, the user holds on the protective housing, inserts the collection portion in solid or semi-solid fecal sample, gathers the sample, then puts into the processing module with the sample that gathers and seals through the bottle lid to this realizes gathering solid or semi-solid sample.
Further, the bottle cap is internally provided with an air cavity, the air cavity is communicated with the inside of the collecting tube, a through hole for communicating the air cavity with the outside is formed in one end of the bottle cap, far away from the collecting tube, of the bottle cap, a first soft rubber sealing layer capable of deforming is arranged in the collecting tube, a second soft rubber sealing layer capable of deforming is arranged at the through hole, the first soft rubber sealing layer and the second soft rubber sealing layer seal part of the collecting tube and the air cavity, the second soft rubber sealing layer is pressed, the bottom of the collecting tube is placed in water sample state excrement, and after the pressing is released, the second soft rubber sealing layer rebounds and absorbs samples into the collecting tube.
Through adopting above-mentioned technical scheme, first soft rubber seal layer divide into cavity and lower cavity on with the collection tube, wherein go up cavity and the inside intercommunication of air cavity, through the sealed of first soft rubber seal layer and second soft rubber seal layer, make last cavity and gas chamber keep sealed, press on the second soft rubber seal layer during the use, make the second soft rubber seal layer to the inside sunken of air cavity because of the exogenic action, simultaneously because the inside sunken of pressure cause first soft rubber seal layer also down the cavity, then insert in the water sample excrement and urine with the collection tube bottom, cancel pressing action, the second soft rubber seal layer is by elasticity restoring to original horizontality, just absorbed a certain amount of water sample excrement and urine sample in the collection tube this moment, thereby realize gathering water sample form excrement and urine.
Further, the lower half part of the circular arc-shaped strainer of the collecting part is of a net structure.
By adopting the technical scheme, as the lower cavity part of the collecting pipe is hollow, the phenomenon that the collected solid or semi-solid sample is blocked in the pipe cavity and cannot come out or is collected more is prevented; and the grid structure can effectively filter larger impurities in the fecal sample when the water sample is collected.
Further, the processing assembly includes:
the bottle body is of a hollow structure, a treatment liquid for preprocessing a sample is contained in the bottle body, a bottle mouth in threaded connection with a bottle cap is formed in one end of the bottle body, and the bottle cap is in threaded connection with the bottle mouth and seals the bottle body;
the limiting block is arranged on the bottle body and abuts against the bottle cover, and the limiting block is used for limiting the depth of the collecting tube inserted into the bottle body.
Through adopting above-mentioned technical scheme, put into the bottle with the excrement and urine sample of gathering, bottle lid threaded connection is on the bottleneck simultaneously and seal the bottle, through the restriction collection pipe of stopper the degree of depth in inserting the bottle for collect the excrement and urine sample in the pipe and fuse with the treatment fluid, shake the bottle simultaneously and make excrement and urine sample and treatment fluid fully fuse, so simplify the pretreatment to the sample.
Further, a hole communicated with the inside of the bottle body is formed in the outer wall of the bottle body along the direction perpendicular to the axis of the bottle body, the hole is close to one end of the bottle mouth, a sealing plug is inserted into the hole, and the hole and the sealing plug are matched to facilitate control of air pressure inside the bottle body.
Through adopting above-mentioned technical scheme, the sealing plug seals the hole during the use for the bottle is inside to be in sealed isolated state, when the sample after the pretreatment is accomplished flows into detection subassembly, because the atmospheric pressure effect makes the sample after the pretreatment unable flow into detection subassembly in, the sample after the pretreatment flows into detection subassembly when pulling out the sealing plug, the sample after the pretreatment stops flowing when the sealing plug inserts in the hole, so that realize controlling the sample volume after the pretreatment that flows into detection subassembly, prevent that the excessive overflow of sample liquid from flowing into detection display area, destroy detection reagent strip.
Further, be provided with the baffle in the bottle, baffle perpendicular to bottle axis sets up and separates into cavity and lower cavity in the bottle, the round hole of the volume of being convenient for control and adding the excrement and urine sample has been seted up at the baffle middle part, the baffle is the funnel form and is close to the round hole department the baffle more and be close to the bottle bottom more, the baffle is convenient for with the interior treatment fluid of last cavity back flow in lower cavity completely.
By adopting the technical scheme, when the bottle body is inverted, the sample pretreatment liquid contained in the bottle body flows to the bottle mouth, if the bottle body is used later, the bottle body is inverted, and the funnel-shaped baffle plate enables the liquid to flow back to the lower cavity completely, so that the liquid is prevented from being detained; because the quantitative of the pretreatment liquid in the bottle body is that the sample amount of the dissolution treatment is in a certain range, the sample needs to pass through the round hole in the plane before being added into the sample pretreatment liquid, when the solid or semi-solid sample collected by the collection tube is too much, the volume of the sample added with the excrement can be controlled by adjusting the diameter of the round hole, and the excessive excrement is trapped on the baffle plate to avoid fusion with the treatment liquid.
Further, the detection assembly includes:
the base is arranged at the bottom of the bottle body, a preservation cavity for storing the pretreated sample is formed in the base, and the preservation cavity is communicated with the inside of the bottle body through a connecting port;
the sealing film is arranged at the connecting port and used for separating the preservation cavity from the lower cavity, the sealing film can resist shaking and is not broken, and the limiting block is removed to enable the collecting tube to be inserted into the sealing film and broken;
the detection block is arranged on the side wall of the base, a detection cavity convenient to detect is formed in the detection block, and the detection cavity is communicated with the storage cavity;
the reagent strip is adhered in the detection block and connected with the inside of the detection cavity, the reagent strip comprises a detection reaction area, a result display area and a water absorption area which are connected in sequence, the detection reaction area is contacted with the detection cavity, and the reagent strip is used for detecting transferrin in a sample;
the sealing block is arranged on the port of one end of the detection block far away from the base, and is used for sealing the reagent strip.
Through adopting above-mentioned technical scheme, the sealing block seals the reagent strip for reagent strip before not using is isolated with the external world, avoid the air to pollute the reagent strip, base fixed mounting is on the bottle bottom, when the treatment fluid dissolves the sample, sealing film will preserve chamber and bottle cavity under separate, after the pretreatment of treatment fluid to the sample is accomplished, take out the stopper, rotate the bottle lid and make the collection tube insert sealing film in and make it break, so will preserve chamber and cavity intercommunication down, make the sample after the pretreatment accomplish get into the detection intracavity in the detection block, sample and reagent strip contact after the pretreatment, provide chromatographic power through the area of absorbing water, make the sample pass through detection reaction zone and result display zone in proper order, finally detect the gyroglobin in the sample, so simplify and detect the sample.
Further, a filter screen is arranged between the detection cavity and the preservation cavity, and the filter screen is used for intercepting and filtering larger impurities in the sample pretreatment liquid.
Through adopting above-mentioned technical scheme, the filter screen is arranged in intercepting and filtering great impurity in the sample pretreatment liquid, makes the solution with the contact of detect reagent strip cleaner, is difficult for blockking up.
Further, the collecting tube, the bottle body, the base and the detecting block are all made of transparent materials.
By adopting the technical scheme, the collection, pretreatment and detection processes of the sample are clear, the detection process can be controlled, and whether the detection operation has errors or not is judged.
In summary, the present application includes the following beneficial technical effects:
the bottle cap is taken out from the bottle body, the solid or semi-solid fecal sample is collected through the collecting part, and when the water sample fecal sample needs to be collected, the collecting tube is used for collecting the water sample fecal sample by pressing the second soft rubber sealing layer, so that the collection of various samples is realized; after collection, the sample is placed into the bottle body and sealed through the bottle cap, then the sample is shaken to be fully fused with the treatment, the limiting block is taken out after the fusion is completed, the bottle cap is screwed to enable the collection tube to puncture the sealing film, the pretreated solution enters the storage cavity and finally enters the detection cavity, the pretreated sample is contacted with the reagent strip and is detected, and therefore collection of samples in various forms is facilitated, pretreatment and detection of the samples are simplified.
Drawings
FIG. 1 is a schematic structural view of the present application;
FIG. 2 is a schematic structural view of the present application showing mainly the acquisition assembly;
FIG. 3 is a schematic cross-sectional view of A-A of FIG. 1;
fig. 4 is an exploded schematic view of the present application.
Reference numerals: 1. a collection assembly; 11. a collection tube; 111. an acquisition unit; 112. a first soft rubber sealing layer; 113. a lower cavity; 114. an upper cavity; 12. a bottle cap; 121. an air cavity; 122. a protective shell; 123. a through hole; 124. a second soft rubber sealing layer; 2. a processing assembly; 21. a bottle body; 211. a bottle mouth; 212. an upper cavity; 213. a lower cavity; 214. a hole; 22. a limiting block; 3. a baffle; 31. a round hole; 4. a sealing plug; 5. a detection assembly; 51. a base; 511. a holding chamber; 52. a sealing film; 53. a detection block; 531. a detection chamber; 54. a reagent strip; 541. detecting a reaction zone; 542. a result display area; 543. a water absorption area; 55. a sealing block; 6. and (3) a filter screen.
Detailed Description
The present application is described in further detail below in conjunction with figures 1-4.
The embodiment of the application discloses a fecal transferrin detection kit integrating sample collection and detection.
Referring to fig. 1, a kit for detecting fecal transferrin by integrating sample collection and detection comprises a collection component 1 for collecting fecal samples, a processing component 2 for processing the samples collected by the collection component 1, and a detection component 5 for detecting the samples processed by the processing component 2, wherein the processing component 2 and the detection component 5 are mutually connected and mutually independent, and the collection component 1 is detachably connected with the processing component 2 and the detection component 5.
Referring to fig. 2 and 3, the collecting assembly 1 comprises a collecting tube 11 and a bottle cap 12, the collecting tube 11 is of a cavity tubular structure, a collecting part 111 is fixedly arranged at the lower end of the collecting tube 11, the collecting part 111 is of an arc-shaped strainer, the lower half part of the arc-shaped strainer of the collecting part 111 is of a net structure, the collecting part 111 is used for collecting solid or semi-solid fecal samples, and the net structure of the collecting part 111 prevents the phenomenon that the collected solid or semi-solid samples cannot be taken out or are collected more by being blocked in the inner cavity of the collecting tube 11; the inside of the collecting pipe 11 is fixedly provided with a first soft rubber sealing layer 112 along the direction perpendicular to the axis of the collecting pipe 11, the first soft rubber sealing layer 112 can deform, and the first soft rubber sealing layer 112 divides the collecting pipe 11 into an upper cavity 114 and a lower cavity 113; the bottle cap 12 is of a cylindrical structure, an air cavity 121 is formed in the bottle cap 12, the upper end of the collecting tube 11 is fixedly arranged on the end face of the bottle cap 12, and the upper cavity 114 of the collecting tube 11 is communicated with the air cavity 121 in the bottle cap 12; an external thread is arranged on the outer side wall of the bottle cap 12, which is close to one end of the collecting tube 11, a protective shell 122 which is convenient for a user to take is fixedly arranged on the outer side wall of one side of the bottle cap 12, which is far away from the collecting tube 11, and anti-skid threads are arranged on the outer side wall of the protective shell 122; the collecting tube 11 and the bottle cap 12 of the embodiment are coaxially and fixedly installed and are of an integral structure poured by hard plastic.
Referring to fig. 2 and 3, a through hole 123 for communicating the air cavity 121 with the outside is formed in one end of the bottle cap 12 far away from the collecting tube 11, a second soft rubber sealing layer 124 is fixedly mounted at the through hole 123, the second soft rubber sealing layer 124 seals the through hole 123, and the first soft rubber sealing layer 112 and the second soft rubber sealing layer 124 cooperate to form a sealing cavity between the upper cavity 114 and the air cavity 121; when in use, the second soft rubber sealing layer 124 is pressed, so that the second soft rubber sealing layer 124 is recessed towards the inside of the air cavity 121 due to the action of external force, meanwhile, the first soft rubber sealing layer 112 is also recessed towards the inside of the lower cavity 113 due to the pressure, then the collecting part 111 of the collecting pipe 11 is inserted into water-sample excrement, and the net structure of the collecting part 111 is fully immersed into the water-sample excrement; the pressing action is canceled, the second soft rubber sealing layer 124 is restored to the original horizontal state by virtue of the elasticity, meanwhile, the first soft rubber sealing layer 112 is also restored to the original horizontal state, at the moment, a certain amount of water sample and excrement samples are sucked into the collecting pipe 11 and enter the lower cavity 113, so that the water sample and excrement are collected, and meanwhile, the larger impurities in the excrement samples can be effectively filtered by the net structure of the collecting part 111; the axis of the through hole 123 and the axis of the collection tube 11 are offset from each other in this embodiment.
Referring to fig. 3 and 4, the processing assembly 2 includes a bottle body 21 and a limiting block 22, wherein the interior of the bottle body 21 is of a hollow structure, a processing liquid for preprocessing a sample is contained in the bottle body 21, a circular bottle opening 211 is formed at one end of the bottle body 21, an internal thread matched with an external thread of a bottle cap 12 is formed on the inner side wall of the bottle opening 211, and the bottle cap 12 is in threaded connection with the bottle opening 211 and seals the bottle body 21; a baffle plate 3 is fixedly arranged in the bottle body 21, the baffle plate 3 is vertically arranged on the axis of the bottle body 21, the baffle plate 3 divides the interior of the bottle body 21 into an upper cavity 212 and a lower cavity 213, and the lower cavity 213 is arranged near the bottom of the bottle body 21; a round hole 31 for communicating the upper cavity 212 with the lower cavity 213 is formed in the middle of the baffle 3, when the collecting tube 11 sends a sample into the lower cavity 213, the sample needs to pass through the round hole 31, and when the solid or semi-solid sample collected by the collecting tube 11 is too much, the round hole 31 blocks the sample, so that the excessive fecal sample is trapped on the baffle 3, and the fusion of the excessive fecal sample and the treatment fluid is avoided; the sample amount of the dissolution treatment of the pretreatment liquid in the bottle body 21 is in a certain range, and the volume amount of the fecal sample can be controlled by adjusting the diameter of the round hole 31; the baffle 3 is funnel-shaped, and the closer to the round hole 31, the closer to the bottom of the bottle body 21, when the bottle body 21 is inverted, the sample pretreatment liquid contained in the bottle body will flow to the bottle mouth 211, if the bottle body needs to be inverted for subsequent use, the funnel-shaped baffle 3 enables the liquid to flow back to the lower cavity 213 completely, and liquid retention is prevented.
Referring to fig. 3 and 4, the stopper 22 is a rubber block of an unsealed annular structure, the stopper 22 is mounted on the bottle body 21 and abuts against the bottle cap 12, the stopper 22 is used for limiting the depth of the collection tube 11 inserted into the bottle body 21, when the bottle cap 12 abuts against the stopper 22, the collection portion 111 of the collection tube 11 is inserted into the lower cavity 213, and the sample is pretreated by the treatment liquid; the stopper 22 is taken out, the bottle cap 12 is rotated to be abutted on the bottle body 21, the collecting part 111 is inserted into the bottom of the bottle body 21, the bottle body 21 is communicated with the detection assembly 5, and the pretreated sample is conveniently discharged into the detection assembly 5 for detection.
Referring to fig. 3 and 4, a hole 214 communicated with the interior of the bottle body 21 is formed in the outer side wall of the bottle body 21 along the direction perpendicular to the axis of the bottle body 21, the hole 214 is close to one end of the bottle mouth 211, the hole 214 is communicated with the upper cavity 212, a sealing plug 4 is inserted into the hole 214, the sealing plug 4 is used for sealing and blocking the hole 214, and the sealing plug 4 is fixedly connected to the bottle body 21 through a rope; when the device is used, the sealing plug 4 seals the hole 214, so that the inside of the bottle body 21 is in a sealed and isolated state, when a pretreated sample needs to flow into the detection assembly 5, the pretreated sample cannot flow into the detection assembly 5 due to the action of air pressure, and when the sealing plug 4 is pulled out, the pretreated sample flows into the detection assembly 5; the pretreated sample inserted into the hole 214 of the sealing plug 4 stops flowing, so that the volume of the pretreated sample flowing into the detection assembly 5 is controlled, and the excessive overflow of the sample liquid into the detection display area is prevented.
Referring to fig. 3 and 4, the detecting assembly 5 includes a base 51, a sealing film 52, a detecting block 53, a reagent strip 54 and a sealing block 55, the base 51 is fixedly installed on the bottom of the bottle 21, a preserving cavity 511 for storing the pretreated sample is formed inside the base 51, and the preserving cavity 511 is communicated with the lower cavity 213; the sealing film 52 is fixedly arranged at the joint of the storage cavity 511 and the lower cavity 213, the sealing film 52 is used for separating the storage cavity 511 from the lower cavity 213, the sealing film 52 is a pokable film, but the sealing film 52 can resist shaking and is not broken, when the limiting block 22 is taken down to enable the collection tube 11 to be inserted into the sealing film 52, the sealing film 52 is broken and the storage cavity 511 and the lower cavity 213 are communicated, so that a sample after pretreatment in the lower cavity 213 is conveniently stored in the storage cavity 511.
Referring to fig. 3 and 4, the detection block 53 is fixedly installed on the side wall of the base 51 and is attached to the side wall of the bottle 21, a detection cavity 531 convenient to detect is formed in the detection block 53, the detection cavity 531 is communicated with the inside of the preservation cavity 511, a filter screen 6 is fixedly installed at the joint of the detection cavity 531 and the preservation cavity 511, and when a sample after pretreatment enters the detection cavity 531 from the preservation cavity 511, the filter screen 6 intercepts and filters larger impurities in the sample pretreatment liquid, so that the solution entering the detection cavity 531 is cleaner and is not easy to block.
Referring to fig. 3 and 4, the contact part of the detecting block 53 and the reagent strip 54 is made of sticky PVC, the reagent strip 54 is divided into a front surface and a back surface, the back surface of the reagent strip 54 has a sticky function, the back surface of the reagent strip 54 is stuck on the detecting block 53, and the front surface of the reagent strip 54 faces to the side far from the outer side wall of the bottle body 21; the reagent strip 54 is composed of a detection reaction area 541, a result display area 542 and a water absorption area 543 which are sequentially connected, wherein the detection reaction area 541 is in contact with the detection cavity 531, and the water absorption area 543 is far away from the detection cavity 531; the detection reaction region 541 is composed of a sample buffer pad and a sample reaction pad, the detection reaction region 541 is made of a glass fiber film or a polyester film, and the sample reaction pad is made of a fecal transferrin antibody 1 marked with colloidal gold and a chromatography quality control antibody marked with colloidal gold; the result display area 542 is made of a nitrocellulose membrane, a fecal transferrin result display area 542 and a chromatography quality control area are arranged on the nitrocellulose membrane, the fecal transferrin result display area 542 contains fecal transferrin antibody 2, and the chromatography quality control area contains an antibody of an anti-chromatography quality control antibody; the water absorption area 543 is made of water absorption material, and the water absorption area 543 is used for providing chromatographic power; the reagent strip 54 of this embodiment is a fecal transferrin colloidal gold test reagent strip 54.
Referring to fig. 3 and 4, a sealing block 55 is fixedly installed on a port of the detection block 53 at one end far away from the base 51, and the sealing block 55 is used for sealing the reagent strip 54, so that the reagent strip 54 is isolated from the outside before the kit is not used, and pollution of air to the reagent strip 54 is avoided, and the final testing precision is affected; the sealing block 55 of the present embodiment is a sealant block.
Referring to fig. 3 and 4, the bottle 21, the base 51 and the detecting block 53 are integrally formed, and the collecting tube 11, the bottle 21, the base 51 and the detecting block 53 are made of transparent materials, so that the collecting, preprocessing and detecting processes of the sample are clear, and the detecting process can be controlled to judge whether the detecting operation has errors.
The working principle of the embodiment of the application is as follows:
taking out the bottle cap 12 from the bottle body 21, collecting solid or semi-solid fecal samples through the collecting part 111, and when the water sample fecal samples are required to be collected, pressing the second soft rubber sealing layer 124 to enable the collecting tube 11 to collect the water sample fecal samples so as to realize the collection of various samples; after collection, the sample is placed into the bottle body 21 and sealed through the bottle cap 12, then the sample is shaken to be fully fused with the treatment, the limiting block 22 is taken out after the fusion is completed, the bottle cap 12 is screwed to enable the collection tube 11 to puncture the sealing film 52, the pretreated solution enters the preservation cavity 511 and finally enters the detection cavity 531, the pretreated sample is contacted with the reagent strip 54 and is detected, and therefore collection of samples in various forms is facilitated, and pretreatment and detection of the samples are simplified.
The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.
Claims (10)
1. The utility model provides a sample collection and detection integrative excrement and urine transferrin detect kit which characterized in that: the device comprises a collection component (1) for collecting a fecal sample, a processing component (2) for processing the sample collected by the collection component (1), and a detection component (5) for detecting the sample processed by the processing component (2), wherein the processing component (2) and the detection component (5) are mutually connected and independent, and the collection component (1) is detachably connected with the processing component (2) and the detection component (5).
2. The integrated fecal transferrin assay kit of claim 1, wherein: the acquisition assembly (1) comprises:
the collecting tube (11), the collecting tube (11) is of a cavity structure, the lower end of the collecting tube (11) is provided with a collecting part (111) for collecting solid or semi-solid fecal samples, and the collecting part (111) is of an arc-shaped strainer;
bottle lid (12), bottle lid (12) are cylindrical structure, collection pipe (11) fixed mounting is on bottle lid (12) terminal surface, be provided with the external screw thread of being convenient for with handling subassembly (2) connection on bottle lid (12), be provided with protective housing (122) that the user of being convenient for took on bottle lid (12).
3. A sample collection and detection integrated fecal transferrin assay kit according to claim 2, wherein: air cavity (121) has been seted up to inside of bottle lid (12), air cavity (121) and collection pipe (11) inside intercommunication, set up on bottle lid (12) one end of keeping away from collection pipe (11) with through-hole (123) of air cavity (121) and outside intercommunication, be provided with first soft rubber seal layer (112) that can take place deformation in collection pipe (11), through-hole (123) department is provided with second soft rubber seal layer (124) that can take place deformation, first soft rubber seal layer (112) and second soft rubber seal layer (124) seal partial collection pipe (11) and air cavity (121), press second soft rubber seal layer (124) and put into the attitude excrement and urine with collection pipe (11) bottom, loosen after pressing second soft rubber seal layer (124) resilience and inhale in collection pipe (11) with the sample.
4. A sample collection and detection integrated fecal transferrin assay kit according to claim 2, wherein: the lower half part of the circular arc-shaped strainer of the collecting part (111) is of a net structure.
5. A sample collection and detection integrated fecal transferrin assay kit according to claim 2, wherein: the processing assembly (2) comprises:
the bottle comprises a bottle body (21), wherein the interior of the bottle body (21) is of a hollow structure, a treatment liquid for preprocessing a sample is contained in the bottle body (21), a bottle opening (211) in threaded connection with a bottle cap (12) is formed in one end of the bottle body (21), and the bottle cap (12) is in threaded connection with the bottle opening (211) and seals the bottle body (21);
the limiting block (22) is arranged on the bottle body (21) and abuts against the bottle cover (12), and the limiting block (22) is used for limiting the depth of the collecting pipe (11) inserted into the bottle body (21).
6. The integrated fecal transferrin assay kit of claim 5, wherein: the bottle is characterized in that a hole (214) communicated with the inside of the bottle body (21) is formed in the outer wall of the bottle body (21) along the direction perpendicular to the axis of the bottle body (21), the hole (214) is close to one end of the bottle mouth (211), a sealing plug (4) is inserted into the hole (214), and the hole (214) is matched with the sealing plug (4) so as to control the air pressure inside the bottle body (21).
7. The integrated fecal transferrin assay kit of claim 5, wherein: be provided with baffle (3) in bottle (21), baffle (3) perpendicular to bottle (21) axis sets up and separates bottle (21) internal partition into cavity (212) and cavity (213) down, round hole (31) convenient to control the volume of adding the excrement and urine sample have been seted up at baffle (3) middle part, baffle (3) are hopper-shaped and are close to baffle (3) of round hole (31) department more and are close to bottle (21) bottom more, baffle (3) are convenient for with the treatment fluid in the cavity (212) return into cavity (213) down completely.
8. The integrated fecal transferrin assay kit of claim 5, wherein: the detection assembly (5) comprises:
the base (51) is arranged at the bottom of the bottle body (21), a preservation cavity (511) for storing the pretreated sample is formed in the base (51), and the preservation cavity (511) is communicated with the inside of the bottle body (21) through a connecting port;
a sealing membrane (52), said sealing membrane (52) being provided at the connection port and being used to separate the holding chamber (511) from the lower cavity (213), said sealing membrane (52) being resistant to shaking and not to rupture, said stopper (22) being removed so that the collection tube (11) is inserted into the sealing membrane (52) and ruptured;
the detection block (53), the detection block (53) is arranged on the side wall of the base (51), a detection cavity (531) convenient for detection is arranged in the detection block (53), and the detection cavity (531) is communicated with the preservation cavity (511);
the reagent strip (54) is stuck in the detection block (53) and is connected with the inside of the detection cavity (531), the reagent strip (54) consists of a detection reaction area (541), a result display area (542) and a water absorption area (543) which are sequentially connected, the detection reaction area (541) is in contact with the detection cavity (531), and the reagent strip (54) is used for detecting the transferrin in a sample;
the sealing block (55), sealing block (55) set up on the port of detection piece (53) one end of keeping away from base (51), sealing block (55) are used for sealing reagent strip (54).
9. The integrated fecal transferrin assay kit of claim 8, wherein: a filter screen (6) is arranged between the detection cavity (531) and the preservation cavity (511), and the filter screen (6) is used for intercepting and filtering larger impurities in the sample pretreatment liquid.
10. The integrated fecal transferrin assay kit of claim 8, wherein: the collecting tube (11), the bottle body (21), the base (51) and the detection block (53) are all made of transparent materials.
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CN202322217195.2U CN220584235U (en) | 2023-08-17 | 2023-08-17 | Fecal transferrin detection kit integrating sample collection and detection |
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CN202322217195.2U CN220584235U (en) | 2023-08-17 | 2023-08-17 | Fecal transferrin detection kit integrating sample collection and detection |
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