CN220385063U - Rabbit model heart continuous blood sampling device - Google Patents

Abstract

The utility model discloses a continuous heart blood sampling device of a rabbit model, which comprises a fixing frame, wherein a fixing part is arranged on the fixing frame; the collecting bottle is movably arranged in the fixed part and is provided with a collecting cavity therein; the liquid inlet end of the blood collection tube is provided with a blood collection needle, and the liquid outlet end of the blood collection tube is connected to the collection bottle; the model clamping frame consists of an annular frame body and a plurality of elastic clamping arms, wherein the upper surface of the annular frame body is vertically and fixedly connected with a supporting vertical rod, and the upper end of the supporting vertical rod is provided with a U-shaped bracket; the model baoding platform, the top surface is the horizontal bearing face, and horizontal bearing face four corners department is provided with model four limbs mounting, still is provided with the decurrent excrement collecting vat of slope, and excrement collecting vat slope lower edge links up the temporary storage bucket that has the horizontal pull, and excrement collecting vat notch department sets up the fretwork grillage. The utility model has the advantages of avoiding pollution in the heart blood sampling process and ensuring the cleanliness of the experiment; the phenomenon of needle running is effectively prevented, and the damage to the rabbit model is reduced; realize single operation, guarantee blood sampling quality.

Description

Rabbit model heart continuous blood sampling device

Technical Field

The utility model relates to the technical field of animal model blood sampling, in particular to a continuous heart blood sampling device of a rabbit model.

Background

Along with the rapid development of medicine, human beings have become more and more rich and various in means for understanding life and treating diseases, and many animal models (such as rabbit models, mouse models and the like) with high physiological similarity with human beings are often used for performing experiments, scientific researches and the like.

In the application and preparation process of the rabbit model polyclonal antibody, heart blood sampling operation is indispensable; the conventional rabbit model heart blood sampling is carried out by repeatedly puncturing and sucking by adopting a syringe, the single blood sampling amount is more than 300ml, the frequent puncturing and blood sampling is complex in operation and difficult to control, and a plurality of blood sampling points are formed on the rabbit model body, so that blood coagulation is easy to cause resource waste; meanwhile, the rabbit model is easy to struggle in the collecting process, so that the phenomenon of needle running is caused, an operator is required to hold the collecting needle for a long time, time and labor are wasted, and the working efficiency is influenced; in addition, once the rabbit model is uncomfortable in the heart blood sampling process, stress reaction can occur, so that the rabbit model is not excreted autonomously, excrement can influence the cleanliness of an experiment site if the excrement cannot be treated in time, and even pollution can be caused.

Disclosure of Invention

The utility model aims to provide a continuous blood sampling device for a rabbit model heart.

In order to achieve the above purpose, the present utility model may adopt the following technical scheme:

the utility model relates to a continuous heart blood sampling device for a rabbit model, which comprises a fixing frame, a collecting bottle, a blood sampling tube, a model clamping frame and a model retaining table; wherein, the fixing frame is provided with a fixing part; the collecting bottle is movably arranged in the fixed part of the fixed frame, and a closed collecting cavity is arranged in the collecting bottle; the liquid inlet end of the blood collection tube is provided with a blood collection needle, and the liquid outlet end of the blood collection tube is connected to the collection bottle; the model clamping frame consists of an annular frame body and a plurality of arc-shaped elastic clamping arms uniformly distributed on the lower surface of the annular frame body, wherein a supporting upright rod is vertically and fixedly connected to the upper surface of the annular frame body, and a U-shaped bracket for clamping and supporting the blood collection tube is arranged at the upper end of the supporting upright rod; the model baoding bench top surface is the horizontal bearing face be provided with model four limbs mounting in the four corners department of horizontal bearing face, be provided with the decurrent excrement collecting vat of slope on the horizontal bearing face, the slope lower edge of excrement collecting vat link up have certainly the temporary storage bucket of horizontal pull on the lateral wall of model baoding bench, the notch department of excrement collecting vat has set up the fretwork grillage that upper surface and horizontal bearing face flush.

The model limb fixing piece is used for firmly fixing the rabbit model for continuous heart blood sampling on the model retaining table, and meanwhile, the model retaining table is matched with the excrement collecting tank which is obliquely downward and the temporary storage hopper which is connected with the lower inclined edge of the excrement collecting tank, so that stress reaction can be effectively collected when the rabbit model is used for blood sampling, excrement which is not produced independently is prevented from polluting in the heart blood sampling process, and the cleanliness of an experiment is ensured; in addition, the elastic clamping arms on the model clamping frame can be used for firmly clamping the rabbit model in the continuous heart blood sampling process, so that the blood sampling tube clamped in the U-shaped bracket at the upper end of the supporting upright rod and the blood sampling needle at the liquid inlet end of the blood sampling tube can move together with the shaking of the rabbit model, the phenomenon of needle running is effectively prevented, repeated needle inserting operation is avoided, the damage to the rabbit model is reduced, and animal welfare is met; in addition, the whole blood sampling device can also guarantee the long-time stable heart blood sampling of the rabbit model, realizes single operation, and does not need the experiment personnel to hold the blood taking needle in a posture for a long time, saves time and labor when guaranteeing blood sampling quality, and greatly improves the safety and the work efficiency of the continuous blood sampling experiment of the rabbit model heart.

Further, the fixing frame comprises a bearing base, a longitudinal supporting rod and an elastic clamping ring; specifically, the support base is a digital display electronic scale, and the top surface of the digital display electronic scale is a horizontal weighing surface for supporting the acquisition bottle; the longitudinal supporting rod is fixedly connected to one side of the bearing base and is vertical to the top surface of the bearing base; the elastic snap ring is of a C-shaped structure, the elastic snap ring is horizontally arranged right above the bearing base and fixedly connected with the upper end of the longitudinal supporting rod, and the inner side of the elastic snap ring is provided with a fixing part for being inserted and placed in the collecting bottle in an adapting mode.

Further, the auxiliary support rod which is longitudinally arranged can be connected to one side of the supporting base, the auxiliary support rod and the longitudinal support rods are respectively located on the left side and the right side of the supporting base, an auxiliary supporting groove which is used for clamping and supporting a U-shaped structure of a blood collection tube is arranged at the upper end of the auxiliary support rod, and the upper end of the auxiliary support rod is higher than a collection bottle which is inserted into an inner fixing part of the elastic snap ring, so that the auxiliary supporting groove is located above the collection bottle, the blood collection tube can be supported upwards in an auxiliary manner when the collection bottle is inserted into the inner fixing part of the elastic snap ring, the blood collection tube connected to the collection bottle is prevented from falling and bending, and the smoothness of the blood collection tube is ensured as much as possible.

Furthermore, for convenient processing and manufacturing and reduced processing cost, the collection bottle consists of a bottle body and a bottle cap screwed on the bottle body, and a liquid amount scale mark is arranged on the bottle body along the height direction, so that the real-time observation of the liquid amount of blood collected in the collection bottle is facilitated; at this time, be provided with on the bottle lid with collection chamber be linked together inlet and extraction opening, the play liquid end of heparin tube connect in on the inlet, be connected with the exhaust tube on the extraction opening, have a one-way extraction valve on the exhaust tube, the outer end of exhaust tube is connected with the air extraction device who is used for sucking the original air in the collection bottle, for further reducing whole blood sampling device's processing cost, this air extraction device specifically can be the syringe cylinder of connecting on the exhaust tube to can easily take out the air in the collection bottle, make and collect the bottle in form inclosed negative pressure vacuum collection chamber, be convenient for in the blood inflow collection chamber.

Furthermore, in order to facilitate the clamping or conducting operation of the blood collection tube, a cut-off buckle can be arranged on the blood collection tube, and the cut-off buckle can easily clamp the conduction of the blood collection tube.

Furthermore, in order to facilitate holding the blood taking needle for puncturing operation, a holding wing which is convenient to hold can be arranged at the tip of the blood taking needle far away from the needle.

Furthermore, in order to facilitate the fixation of the four limbs of the rabbit model lying on the model retaining table, the model four limb fixing parts are elastic magic tape fixed on the horizontal bearing surface; of course, the animal retaining clip with a common ring structure on the market can also be adopted, the animal retaining clip is formed by hinging a lower semicircular arc clamping arm and an upper semicircular arc clamping arm, the sizes of the inner clamping cavities of the upper semicircular arc clamping arm and the lower semicircular arc clamping arm can be adjusted according to the needs when the upper semicircular arc clamping arm and the lower semicircular arc clamping arm are buckled, and the animal retaining clip has a structure similar to handcuffs.

Further, in order to facilitate the horizontal outward extraction of the temporary storage hopper, a handle convenient to hold can be arranged on the outer wall of the drawing side of the temporary storage hopper.

Drawings

Fig. 1 is a schematic structural view of the present utility model.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

It should be noted that all directional indicators (such as up, down, left, right, front, and rear … …) in the embodiments of the present utility model are merely used to explain the relative positional relationship, movement, etc. between the components in a particular posture (as shown in the drawings), and if the particular posture is changed, the directional indicator is changed accordingly.

In the present utility model, unless specifically stated and limited otherwise, the terms "connected," "affixed," and the like are to be construed broadly, and for example, "affixed" may be a fixed connection, a removable connection, or an integral body; can be mechanically or electrically connected; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

As shown in fig. 1, the continuous blood sampling device for rabbit model heart of the utility model comprises a fixing frame 1, a collecting bottle 2, a blood sampling tube 3, a model clamping frame 4 and a model retaining table 5.

Wherein, the fixing frame 1 is provided with a fixing part; the collection bottle 2 is movably arranged in the fixed part of the fixed frame 1, so that the collection bottle 2 is firmly borne by the fixed frame 1, hands are liberated, the collection bottle 2 is prevented from being held by an operator for a long time, and in addition, a closed collection cavity is arranged in the collection bottle 2 and is used for aseptically collecting heart blood of a rabbit model; the liquid inlet end of the blood collection tube 3 is provided with a blood collection needle 6, and the liquid outlet end of the blood collection tube is connected to the collection bottle 2; the model clamping frame 4 is used for clamping and fixing the chest of the rabbit model, a supporting upright rod 7 is vertically and fixedly connected to the model clamping frame, and a U-shaped bracket 8 for clamping and supporting the blood collection tube 3 is arranged at the upper end of the supporting upright rod 7; the top surface of the model retaining table 5 is a horizontal bearing surface 9 for bearing a rabbit model, model limb fixing pieces 10 for fixing the four limbs of the rabbit model are arranged at four corners of the horizontal bearing surface 9, an excrement collecting tank 11 which is inclined downwards is arranged on the horizontal bearing surface 9, a temporary storage hopper 12 which is horizontally pulled out from the side wall of the model retaining table 5 is connected to the inclined lower edge of the excrement collecting tank 11, a hollowed-out plate frame 24 with the upper surface being flush with the horizontal bearing surface 9 is arranged at the notch of the excrement collecting tank 11, and hollowed-out gaps on the hollowed-out plate frame 24 can ensure that excrement of the rabbit model falls into the excrement collecting tank 11; the rabbit model for continuous heart blood sampling is firmly fixed on the model retaining table 5 through the model limb fixing piece 10, meanwhile, the model retaining table 5 is matched with the excrement collecting tank 11 which is inclined downwards and the temporary storage hopper 12 which is connected with the inclined lower edge of the excrement collecting tank 11, so that stress reaction can be effectively collected when the rabbit model is used for blood sampling, excrement which is not produced independently is not produced, pollution caused in the heart blood sampling process of the rabbit model is avoided, and the cleanliness of an experiment is ensured.

Specifically, the fixing frame 1 comprises a bearing base 1.1, a longitudinal supporting rod 1.2 and an elastic clamping ring 1.3; the support base 1.1 can be a digital display electronic scale, and the top surface of the digital display electronic scale is a horizontal weighing surface for supporting the acquisition bottle 2 and weighing in real time; the longitudinal support rod 1.2 is fixedly connected to one side of the supporting base 1.1 and is vertical to the top surface of the supporting base 1.1 (namely the horizontal weighing surface of the digital display electronic scale); the elastic snap ring 1.3 is of a C-shaped structure, the elastic snap ring 1.3 is horizontally arranged right above the supporting base 1.1 and fixedly connected with the upper end of the longitudinal supporting rod 1.2, and a fixing part for adapting and inserting the collecting bottle 2 is formed on the inner side of the elastic snap ring 1.3. In addition, can also connect the auxiliary stay 13 that vertically set up in one side of bearing base 1.1, auxiliary stay 13 and vertical branch 1.2 should be located the left and right sides of bearing base 1.1 respectively, the upper end of auxiliary stay 13 is provided with the auxiliary bracket 14 that is used for the card to hold in the palm the U-shaped structure of heparin tube 3, and the upper end of auxiliary stay 13 should be higher than the collection bottle 2 in inserting the inboard fixed part of snap ring 1.3, thereby make auxiliary bracket 14 be located collection bottle 2 top, can assist upwards to hold up heparin tube 3 when collection bottle 2 inserts in the inboard fixed part of snap ring 1.3, avoid connecting the heparin tube 3 whereabouts bending on collection bottle 2, guarantee that heparin tube 3 is unblocked as far as possible.

The collection bottle 2 is similar to the structure of the existing blood collection tube in the market, and consists of a bottle body 2.1 and a bottle cap 2.2 screwed on the bottle body 2.1, so that the collection bottle is convenient to process and manufacture, and the processing cost is reduced; at this time, a liquid inlet 15 and an air extraction opening 16 which are communicated with the collection cavity are arranged on the bottle cap 2.2, the liquid outlet end of the blood collection tube 3 is connected to the liquid inlet 15, the air extraction opening 16 is connected with an air extraction tube 17, the air extraction tube 17 is provided with a one-way air extraction valve 18, the outer end of the air extraction tube 17 is connected with an air extraction device for sucking the air in the collection bottle 2, and in order to further reduce the processing cost of the whole blood collection device, the air extraction device can be specifically an injector needle cylinder 19 connected to the air extraction tube 17, so that the air in the collection bottle 2 can be easily extracted outwards through the injector needle cylinder 19, a closed negative pressure vacuum collection cavity is formed in the collection bottle 2, and the blood is convenient to flow into the collection cavity. In addition, in order to facilitate real-time observation of the blood volume collected in the collection bottle 2, a volume scale mark 20 should be provided on the bottle body 2.1 along the height direction.

The blood collection tube 3 is a flexible tube body, so as to facilitate clamping or conducting operation on the blood collection tube 3, a cut-off buckle 21 can be arranged on the blood collection tube 3, and the cut-off buckle 21 has the same structure as a flow stopping clamp on the existing indwelling needle, can be operated by one hand, and can easily clamp the conduction of the blood collection tube 3. In addition, in order to facilitate the puncturing operation of the lancet 6, a grip wing 22 for facilitating the gripping may be provided at a distal end of the lancet 6 from the tip of the needle.

The model clamping frame 4 is composed of an annular frame body 4.1 and a plurality of arc-shaped elastic clamping arms 4.2 uniformly distributed on the lower surface of the annular frame body 4.1, and the supporting upright rod 7 is vertically and fixedly connected to the upper surface of the annular frame body 4.1. In addition, four groups of elastic clamping arms 4.2 are arranged on the lower surface of the annular frame body 4.1 along the circumferential direction, the four groups of elastic clamping arms 4.2 are clamped on two sides of the chest of the rabbit model in pairs, so that a circular cavity on the inner side of the annular frame body 4.1 just faces the heart of the rabbit model, an operator can conveniently hold the blood taking needle 6 for heart blood taking puncture operation, the whole model clamping frame 4 together with the supporting upright rod 7 can be stably fixed on the body of the rabbit model, and then in the heart blood sampling process of the rabbit model, the blood sampling tube 3 which is clamped in the U-shaped bracket 8 at the upper end of the supporting upright rod 7 can move together with the left and right shaking of the rabbit model, so that the blood sampling needle 6 on the liquid inlet end of the blood sampling tube 3 is effectively prevented from running, repeated needle inserting operation is avoided, the damage to the rabbit model is reduced, and animal welfare is met.

The model fixing table 5 is a rectangular table, the model four-limb fixing parts 10 at four corners of the top surface of the model fixing table 5 can be elastic magic tape fixed on the horizontal bearing surface 9, so that the adhesion position of the elastic magic tape can be easily adjusted according to the thickness of the four limbs of the rabbit model while fixing the four limbs of the rabbit model lying on the model fixing table 5. Of course, the model limb fixing part 10 can also adopt an animal retaining clip with a conventional ring structure, which is formed by hinging a lower semicircular arc clamping arm and an upper semicircular arc clamping arm, and the structure of the animal retaining clip is similar to handcuffs, and the upper semicircular arc clamping arm and the lower semicircular arc clamping arm can adjust the size of the inner clamping cavity of the upper semicircular arc clamping arm and the lower semicircular arc clamping arm as required when being buckled, so that the limbs of the rabbit model can be firmly clamped. In addition, in order to facilitate the timely treatment of excrement by horizontally and outwards withdrawing the temporary storage hopper 12, a handle 23 which is convenient to hold can be arranged on the outer wall of the drawing side of the temporary storage hopper 12.

When in use, firstly, the chest of the rabbit model is horizontally laid and fixed on the model retaining table 5, and the buttocks of the rabbit model are positioned on the hollowed-out plate frame 24; then the model clamping frame 4 is clamped on the chest of the rabbit model, so that the circular cavity at the inner side of the annular frame body 4.1 is ensured to be opposite to the heart of the rabbit model; after that, the collection bottle 2 can be fixed and connected with the blood collection tube 3, the blood collection needle 6 is operated to perform heart blood collection and puncture operation of the rabbit model, and before the puncture operation of the blood collection needle 6 is performed, the blood collection tube 3 is clamped by the closure button 21, and the air in the collection bottle 2 is pumped out by the syringe needle cylinder 19, so that the interior of the collection bottle 2 is kept in a vacuum negative pressure state; after the blood taking needle 6 pierces the heart of the rabbit model, the closure button 21 is released, so that blood continuously flows into the collection bottle 2 through the blood taking tube 3, and the continuous heart blood taking operation of the rabbit model is completed.

After the collection bottle 2 collects the heart blood of the full rabbit model, the retaining buckle 21 can be operated again to prick and close the blood collection tube 3, so that the collection bottle 2 is replaced.

The whole blood sampling device can ensure long-time stable heart blood sampling of the rabbit model, does not need to hold the blood taking needle 6 in a posture for a long time by an experimenter, realizes single operation, saves time and labor while guaranteeing blood sampling quality, and greatly improves the safety and the working efficiency of continuous blood sampling experiments of the rabbit model heart.

Claims (10)

1. A continuous blood sampling device of rabbit model heart, its characterized in that: comprising

The fixing frame is provided with a fixing part;

the collecting bottle is movably arranged in the fixed part of the fixing frame, and a closed collecting cavity is arranged in the collecting bottle;

the liquid inlet end of the blood collection tube is provided with a blood collection needle, and the liquid outlet end of the blood collection tube is connected to the collection bottle;

the model clamping frame consists of an annular frame body and a plurality of arc-shaped elastic clamping arms uniformly distributed on the lower surface of the annular frame body, wherein a supporting upright rod is vertically and fixedly connected to the upper surface of the annular frame body, and a U-shaped bracket for clamping and supporting the blood collection tube is arranged at the upper end of the supporting upright rod;

the model baoding platform, its top surface is the horizontal bearing face the four corners department of horizontal bearing face is provided with model four limbs mounting, is provided with the decurrent excrement collecting vat of slope on the horizontal bearing face, the slope lower edge of excrement collecting vat link up have certainly the temporary storage bucket of horizontal pull on the lateral wall of model baoding platform, the notch department of excrement collecting vat has set up the fretwork grillage that upper surface and horizontal bearing face flush.

2. The rabbit model heart continuous blood sampling device of claim 1, wherein: the fixing frame comprises

A supporting base;

the longitudinal support rod is fixedly connected to one side of the bearing base;

and the elastic clamping ring is of a C-shaped structure, is horizontally arranged right above the bearing base, is fixedly connected with the upper end of the longitudinal supporting rod, and forms a fixing part on the inner side of the elastic clamping ring for being matched with the collecting bottle.

3. The rabbit model heart continuous blood sampling device according to claim 2, wherein: the support base is a digital display electronic scale, and the top surface of the digital display electronic scale is a horizontal weighing surface.

4. The rabbit model heart continuous blood sampling device according to claim 2, wherein: one side of the bearing base is connected with a longitudinally arranged auxiliary supporting rod, and the upper end of the auxiliary supporting rod is provided with an auxiliary bracket with a U-shaped structure.

5. The rabbit model heart continuous blood sampling device of claim 1, wherein: the collecting bottle consists of a bottle body and a bottle cap screwed on the bottle body, and liquid amount scale marks are arranged on the bottle body along the height direction.

6. The rabbit model heart continuous blood sampling device according to claim 5, wherein: the bottle cap is provided with a liquid inlet and an air extraction opening which are communicated with the collecting cavity, the liquid outlet end of the blood sampling tube is connected to the liquid inlet, the air extraction opening is connected with an air extraction tube, the air extraction tube is provided with a one-way air extraction valve, and the outer end of the air extraction tube is connected with an air extraction device.

7. The rabbit model heart continuous blood sampling device of claim 1, wherein: the blood collection tube is provided with a closure button.

8. The rabbit model heart continuous blood sampling device of claim 1, wherein: the tip of the blood taking needle far away from the needle is provided with a holding wing.

9. The rabbit model heart continuous blood sampling device of claim 1, wherein: the model limb fixing piece is an elastic magic tape fixed on the horizontal bearing surface.

10. The rabbit model heart continuous blood sampling device of claim 1, wherein: a buckle is arranged on the outer wall of the drawing side of the temporary storage hopper.