CN210130811U - Multi-parameter and multi-functional eye measuring instrument based on optical coherence tomography - Google Patents
Multi-parameter and multi-functional eye measuring instrument based on optical coherence tomography Download PDFInfo
- Publication number
- CN210130811U CN210130811U CN201920552791.7U CN201920552791U CN210130811U CN 210130811 U CN210130811 U CN 210130811U CN 201920552791 U CN201920552791 U CN 201920552791U CN 210130811 U CN210130811 U CN 210130811U
- Authority
- CN
- China
- Prior art keywords
- lens group
- measuring instrument
- eye
- eye measuring
- lens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Eye Examination Apparatus (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The utility model provides a multi-parameter and multi-functional eye measuring instrument based on optical coherence tomography; this measuring apparatu the utility model discloses a measuring apparatu simple structure, reasonable in design, the optical path regulation and control of being convenient for realizes the OCT and consults the conversion between the time domain and the frequency domain of arm light path for single equipment has possessed multiple imaging function, and the performance of very big improve equipment has satisfied common ophthalmology and has measured the demand, and the doctor of being convenient for obtains the parameter of measuring each position of eyes, has practiced thrift the purchase cost of equipment, maintenance cost and the operation training cost of corresponding equipment, the administrative cost of equipment.
Description
Technical Field
The utility model belongs to the technical field of ophthalmology inspection instrument, concretely relates to multi-parameter, multi-functional eyes measuring apparatu based on optics coherent tomography.
Background
Optical Coherence Tomography (OCT) is an emerging imaging technique, which has the advantages of non-invasive, high-resolution, quantitative evaluation in vivo, and the like from 1991 to the present, and the working principle of the OCT is to perform high-resolution tomographic scanning on microstructures inside biological tissues or other scattering media by using the low coherence interference principle in combination with confocal scanning, and reconstruct an image of a measured sample by a computer. With the development of corresponding software algorithms, the method has been widely applied to clinical applications such as blood flow imaging and eye detection. Among them, in terms of eye detection, OCT has become the "gold standard" for eye detection due to its superior resolution.
OCT is currently divided into two major categories: time domain TD-OCT and frequency domain SD-OCT. The working principle of the TD-OCT is that light emitted by a low-coherence light source is divided into two beams at an optical fiber coupler, one beam of reference light is emitted to a reference arm and reflected back after reaching a plane mirror, the other beam of measuring light is emitted to a sample and scattered back after passing through the sample, and the reference beam is reflected back and interfered with backward scattering light generated by the measuring beam on the sample at the optical fiber coupler. Then the photoelectric sensor receives the interference signal and processes the signal, and finally a computer processes the signal to obtain a tomographic image of the sample. Through the scanning of the longitudinal reference arm, the point-by-point acquisition of the longitudinal information (depth direction) in the sample is realized. Due to the limitation of the scanning mechanism, the axial line scanning speed (A-line) of the TD-OCT is generally limited to 2-4kHz, and the imaging speed of the TD-OCT is greatly limited.
Different from the working principle of the TD-OCT system, the SD-OCT replaces the photoelectric sensor with a spectrometer at a light receiving end, and a longitudinal scanning reference arm is not needed any more, so that the scanning speed is improved, and the stability is improved. Specifically, interference spectrum data received by the spectrometer is analyzed through inverse Fourier transform, and finally longitudinal information of a measured substance is obtained, and image data collection and analysis are completed through a computer. The system realizes effective conversion of two optical paths through a time domain and frequency domain optical path changing device, achieves multi-parameter detection of each part of the eye, and realizes multiple functions of the measuring instrument.
At present, the ophthalmic examination instruments on the market are all aimed at a certain eye parameter target, such as measuring the axial length of the eye, imaging the retina by adopting single TD-OCT or SD-OCT, and the like, and can meet the clinical requirements on single target imaging. However, if imaging examination of a plurality of targets is required, a plurality of examination instruments are required, and as research on ophthalmic diseases progresses, some diseases are associated with a plurality of parts of the eye, that is, ophthalmic diseases occur, and it is necessary to image morphological structures of the plurality of parts.
Therefore, the traditional ophthalmologic examination apparatus for a single target is difficult to adapt to practical requirements through one-time examination items, and needs a plurality of detection devices to detect a patient. This not only increases the purchase cost of the inspection instrument, but also increases the maintenance cost of the machine, the training cost of the personnel involved, and the like.
Disclosure of Invention
The utility model aims at providing a multi-parameter, multi-functional eyes measuring apparatu to the not enough of current ophthalmology inspection instrument, can once measure a plurality of parameters, including the anterior segment of multile, retina, the axial length isoparametric of eye.
In order to achieve the technical purpose, the technical scheme of the utility model is as follows: a multi-parameter and multi-functional eye measuring instrument based on optical coherence tomography comprises a light source, an optical fiber coupler, a reference arm, a sample arm, a detector and a processor;
the light source is used for providing an initial light beam;
the optical fiber coupler is used for dividing the initial light beam into two parts, respectively entering the reference arm and the sample arm, and receiving the light beams returned by the reference arm and the sample arm;
the reference arm comprises a frequency domain module and a time domain module which are arranged in parallel, the frequency domain module comprises a collimating mirror and a frequency domain zero optical path position changing device, and the time domain module comprises a collimating mirror and a time domain optical delay line device;
the sample arm is used for scanning the eye to be detected;
the detector is used for receiving an interference type formed by interference of light beams returned by the reference arm and the sample arm and converting the interference type into an electric signal; the device comprises a spectrometer and a photoelectric sensor which are arranged in parallel;
the processor is used for receiving the electric signals and imaging.
The utility model discloses an eye measuring instrument, through setting up parallel frequency domain zero optical path position changing device and time domain optical delay line device, and spectrum appearance and photoelectric sensor respectively at sample arm and detector; therefore, the light beam emitted by the light source can be selected to adopt a frequency domain optical path or a frequency domain optical path, and the specific frequency domain optical path is as follows: light emitted by the light source is divided into two parts by the optical fiber coupler, one part enters the reference arm, the light beam entering the reference arm can enter the frequency domain module through the frequency domain zero optical path position changing device, and finally the light returned by the reflector interferes with the light returned by the sample arm, so that the light is detected and imaged by the spectrometer; the time domain optical path is: the light emitted by the light source is divided into two parts by the optical fiber coupler, one part enters the reference arm, the light beam entering the reference arm can enter the time domain module by the optical delay line device, and finally the light returned by the reflector interferes with the light returned by the sample arm, so that the photoelectric detector and the processor detect and image.
Thus, the time domain OCT module can be used for measuring the axial length of the eye, and the frequency domain OCT module is used for imaging the eye so as to realize the examination of multiple parts of the eye.
Further, the frequency domain zero optical path position changing device includes: the collimating lens and the movable plane mirror have simple structure and are convenient for optical path adjustment and correspondence.
Preferably, the movable flat mirrors comprise motor-driven guide rails and flat mirrors located on the guide rails.
The time domain optical delay line device mainly aims at quickly changing the optical path of the reference arm, and preferably comprises a circular turntable and a plurality of reflectors which are fixed on the turntable at a certain angle, so that the time domain optical delay line device is simple in structure and convenient for optical path adjustment and correspondence.
Further, the light source is a laser light source with the central wavelength of 840nm and the bandwidth range of 49nm, and the average power is 20 mW. The use of near infrared light waves can reduce tissue scattering to achieve greater imaging depths; the narrow bandwidth ensures that the image is not affected by unavoidable movements of the eye itself, such as micro saccades.
Further, the sample arm comprises a collimating lens, a fast scanning galvanometer, a slow scanning galvanometer, a first lens group and a second lens group, after light enters, the light sequentially passes through the collimating lens, the fast scanning galvanometer and the slow scanning galvanometer and then enters the first lens group or the second lens group, the first lens group is a diverging lens group, the second lens group is a condensing lens group, and the first lens group and the second lens group can be switched. The first lens group is a divergent lens group, so that scanning light rays are parallel light before entering eyes, and then can be focused on the fundus after passing through a light ray system of the eyes, and the fundus can be imaged; the second lens group is a condenser lens group, so that the entered parallel light can be focused in the anterior chamber of the eye through the first lens group, and the anterior chamber of the eye is imaged. By switching the first lens group and the second lens group, the whole device can image the fundus and the anterior chamber of the eye, so that more information can be acquired.
Preferably, the first lens group comprises two focusing lenses which are parallel to each other, and the two focusing lenses form a 4f system, so that the structure is simple, and the optical path regulation is convenient.
Preferably, the second lens group is composed of a focusing lens, so that focusing is facilitated, and system optical path regulation is facilitated.
Preferably, the spectrometer comprises a collimating lens, a grating, a focusing lens and a CMOS line camera.
The utility model discloses a measuring apparatu simple structure, reasonable in design, the optical path of being convenient for is regulated and control, realize OCT and refer to the time domain of arm light path and the conversion between the frequency domain, make single equipment possess multiple imaging function, greatly improve equipment's performance, to common ophthalmology measurement demand, like anterior chamber formation of image, the formation of image of eye ground retina, the eye axis length is measured, blood flow formation of image etc. can both satisfy, thereby be convenient for the doctor obtains the parameter of measuring each position of eyes, the purchase cost of having practiced thrift equipment, the maintenance cost, and the operation training cost of corresponding equipment, the administrative cost of equipment.
Drawings
Fig. 1 is a schematic structural diagram of a multi-parameter, multi-functional eye-measuring instrument based on optical coherence tomography according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a frequency domain zero optical path position changing device according to an embodiment of the present invention;
fig. 3 is a schematic structural diagram of a time domain optical delay line device according to an embodiment of the present invention.
Detailed Description
The technical solution of the present invention will be described in detail with reference to the accompanying drawings and specific embodiments.
Referring to fig. 1, the multi-parameter, multi-functional eye measuring apparatus based on optical coherence tomography comprises a light source 1, a fiber coupler 2, a reference arm, a sample arm, a detector and a processor.
The reference arm comprises a frequency domain module and a time domain module which are arranged in parallel, the frequency domain module comprises a collimating mirror 3 and a frequency domain zero optical path position changing device 5, as shown in fig. 2, the frequency domain zero optical path position changing device 5 is a movable plane mirror and comprises a motor drive guide rail 51 and a plane mirror 52 positioned on the guide rail, and the plane mirror 52 moves by the movement of the motor drive guide rail 51 to change the length of the reference arm, so that the length of the reference arm is consistent with the length of the sample arm to be measured. The time domain module comprises a collimating mirror 3 and a time domain optical delay line device 4, wherein the structure of the time domain optical delay line device 4 is shown in fig. 3; comprises a circular turntable 41 and a plurality of reflectors 42 fixed on the turntable 41 at a certain angle; the mirror 42 rotates with the turntable 41, and the position of the light hitting the mirror 42 changes when the mirror rotates, so that the reference arm length changes.
The sample arm comprises a collimating lens 3, a fast scanning galvanometer 6, a slow scanning galvanometer 7, a first lens group and a second lens group which can be switched, wherein the first lens group is a divergent lens group, the second lens group is a convergent lens group, the first lens group consists of two focusing lenses 8 which are parallel to each other, and the two focusing lenses 8 form a 4f system; the second lens group consists of a focusing lens 8; the detector comprises a spectrometer and a photoelectric sensor 9 which are arranged in parallel, wherein the spectrometer comprises a collimating mirror 3, a grating 10, a focusing lens 8 and a CMOS linear array camera 11; the processor is a computer 12.
A frequency domain zero optical path position changing device 5 and a time domain optical delay line device 4 which are parallel are respectively arranged on a sample arm and a detector, and a spectrometer and a photoelectric sensor 9 are arranged on the sample arm and the detector; therefore, the light beam emitted by the light source can be selected to adopt a frequency domain optical path or a frequency domain optical path.
The utility model discloses the light path of the frequency domain OCT of measuring apparatu does, light source 1 sends a bundle of light and gets into and be divided into two on the optical fiber coupler 2, a branch gets into reference arm, get into zero optical path position of frequency domain change device, specifically, become a bundle of parallel light through an optical collimator 3, then the parallel light is beaten on a mobilizable level crossing 52, because the mobility of level crossing 52, make the system can adjust the position of level crossing according to the difference of formation of image target (if form images or form images to the bottom of the eye to the anterior chamber), and then the arm length of adjustment reference arm, match on the optical path with the target that will form images. The light entering the reference arm is reflected by the mirror 52 and then returned to the fiber coupler 2. The other beam of light enters the sample arm, passes through the slow scanning galvanometer 6, passes through the fast scanning galvanometer 7, passes through the lens group matched with the target, namely the first lens group or the second lens group, and is focused and scanned on the imaged target, the scanning light returns through the original path after being reflected in the tissue, is interfered with the light returning from the reference arm in the optical fiber coupler 2, then enters the detector part, namely a spectrometer consisting of the collimating lens 3, the grating 10, the focusing lens 8 and the CMOS linear array camera 11, the optical signal is converted into an electrical signal, and finally the signal is transmitted to the electronic computer 12 for imaging.
The utility model discloses time domain OCT light path of measuring apparatu does, and light source 1 sends a bundle of light and gets into and be divided into two on the optical fiber coupler 2, and a bundle of entering reference arm gets into time domain optics delay line device 4, specifically, goes optics delay line device 4 after 3 collimators, then the original way returns, enters into in the optical fiber coupler 2. The other beam of light enters the sample arm, passes through the slow scanning galvanometer 6, passes through the fast scanning galvanometer 7, passes through the lens group matched with the target, namely the first lens group or the second lens group, and is focused and scanned on the imaged target, the scanning light returns through the original path after being reflected in the tissue, is interfered with the light returning from the reference arm in the optical fiber coupler 2, then enters the photoelectric sensor part, the optical signal is converted into an electric signal by the photoelectric sensor 9, and finally the signal is transmitted to the electronic computer 12 for imaging.
The light source of the OCT system determines the level of performance that can be achieved, the center wavelength determines the longitudinal resolution, and the depth of detection that can be achieved by the system. Therefore, the light source 1 of the measuring instrument of the present embodiment preferably uses a laser source with a center wavelength of 840nm and a bandwidth range of 49nm, which is customized by a research group, and has an average power of 20mW, so that the axial resolution is less than 12 μm, thereby providing possibility for realizing high-sensitivity detection and rapid image acquisition in human eyes. Meanwhile, the near infrared light waves can reduce tissue scattering so as to achieve larger imaging depth; the narrow bandwidth ensures that the image is not affected by unavoidable movements of the eye itself, such as micro saccades.
Meanwhile, in the embodiment, a first lens group and a second lens group which can be switched are arranged, the first lens group is a divergent lens group, so that scanning light rays are parallel light before entering eyes, and then can be focused on the fundus after passing through a light ray system of the eyes, so that the fundus can be imaged; the second lens group is a condenser lens group, so that the entered parallel light can be focused in the anterior chamber of the eye through the first lens group, and the anterior chamber of the eye is imaged. By switching the first lens group and the second lens group, the whole device can image the fundus and the anterior chamber of the eye, so that more information can be acquired.
Therefore, the utility model discloses eye measuring apparatu has had time domain OCT and frequency domain OCT module simultaneously, and has optional first lens group and second lens group, can be respectively to fundus and anterior segment focus formation of image, can utilize the frequency domain module to obtain the structural information of eyes like this, like anterior chamber structural information, retina structural information to can introduce through corresponding imaging algorithm, and then can image to the blood flow. And the anterior chamber and the fundus of the eye are imaged by changing the length of the reference arm in the frequency domain and the corresponding focusing lens to image the target. And the length of the axis of the eye and the like are measured by a time domain system, so that important parameters in the ophthalmologic examination are basically covered.
Just the utility model discloses a measuring apparatu through the component design of preferred each structure for simple structure, the different formation of image position optical focusing of the adjustment of being convenient for, reference arm optical path and correspond the problem, the utility model discloses a measuring apparatu scanning is quick, weak point consuming time, and the doctor of being convenient for obtains measuring the parameter of each position of eyes, has practiced thrift the purchase cost of equipment, maintenance cost and the operation training cost of corresponding equipment, the administrative cost of equipment.
Variations and modifications to the above-described embodiments may occur to those skilled in the art, which fall within the scope and spirit of the above description. Therefore, the present invention is not limited to the specific embodiments disclosed and described above, and some modifications and variations of the present invention should fall within the scope of the claims of the present invention. Furthermore, although specific terms are employed herein, they are used in a generic and descriptive sense only and not for purposes of limitation.
Claims (10)
1. The multi-parameter and multi-functional eye measuring instrument based on optical coherence tomography is characterized by comprising a light source, an optical fiber coupler, a reference arm, a sample arm, a detector and a processor;
the light source is used for providing an initial light beam;
the optical fiber coupler is used for dividing the initial light beam into two parts, respectively entering the reference arm and the sample arm, and receiving the light beams returned by the reference arm and the sample arm;
the reference arm comprises a frequency domain module and a time domain module which are arranged in parallel, the frequency domain module comprises a collimating mirror and a frequency domain zero optical path position changing device, and the time domain module comprises a collimating mirror and a time domain optical delay line device;
the sample arm is used for scanning the eye to be detected;
the detector is used for receiving an interference type formed by interference of light beams returned by the reference arm and the sample arm and converting the interference type into an electric signal; the device comprises a spectrometer and a photoelectric sensor which are arranged in parallel;
the processor is used for receiving the electric signals and imaging.
2. An eye measuring instrument according to claim 1, wherein the frequency domain zero optical path position changing means comprises: a collimating lens and a movable flat mirror.
3. An eye measuring instrument according to claim 2, wherein the movable flat mirror comprises a motor-driven guide rail and a flat mirror located on the guide rail.
4. The eye measuring instrument of claim 1, wherein the time domain optical delay line device comprises a circular turntable, and a plurality of mirrors fixed at an angle to the turntable.
5. An eye measuring instrument according to claim 1, wherein the light source is a laser source with a central wavelength of 840nm and a bandwidth of 49nm, and an average power of 20 mW.
6. An eye measuring instrument according to claim 1, wherein the sample arm comprises a collimating lens, a fast scanning galvanometer, a slow scanning galvanometer, and a first lens group and a second lens group, after entering, the light sequentially passes through the collimating lens, the fast scanning galvanometer, the slow scanning galvanometer, and then enters the first lens group or the second lens group, the first lens group is a condensing lens group, the second lens group is a diverging lens group, and the first lens group and the second lens group are switchable.
7. An eye measuring apparatus according to claim 6, wherein the first lens group comprises two focusing lenses parallel to each other, and the two focusing lenses form a 4f system.
8. An eye measuring instrument according to claim 6, wherein said second lens group is composed of a focusing lens.
9. The eye measuring instrument of claim 1, wherein the spectrometer comprises a collimating lens, a grating, a first focusing lens, and a CMOS line camera.
10. The eye measuring instrument of claim 1, wherein the processor is a terminal device having a memory function.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920552791.7U CN210130811U (en) | 2019-04-23 | 2019-04-23 | Multi-parameter and multi-functional eye measuring instrument based on optical coherence tomography |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920552791.7U CN210130811U (en) | 2019-04-23 | 2019-04-23 | Multi-parameter and multi-functional eye measuring instrument based on optical coherence tomography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210130811U true CN210130811U (en) | 2020-03-10 |
Family
ID=69703973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920552791.7U Active CN210130811U (en) | 2019-04-23 | 2019-04-23 | Multi-parameter and multi-functional eye measuring instrument based on optical coherence tomography |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210130811U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110013212A (en) * | 2019-04-23 | 2019-07-16 | 广东唯仁医疗科技有限公司 | Optical coherence tomography-based multi-parameter, multi-function ophthalmometer |
| CN117582169A (en) * | 2023-10-11 | 2024-02-23 | 广东唯仁医疗科技有限公司 | Multifunctional eye parameter measurement method and device and computer storage medium |
-
2019
- 2019-04-23 CN CN201920552791.7U patent/CN210130811U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110013212A (en) * | 2019-04-23 | 2019-07-16 | 广东唯仁医疗科技有限公司 | Optical coherence tomography-based multi-parameter, multi-function ophthalmometer |
| CN110013212B (en) * | 2019-04-23 | 2024-04-16 | 广东唯仁医疗科技有限公司 | Multi-parameter and multi-functional eye measurement instrument based on optical coherence tomography |
| CN117582169A (en) * | 2023-10-11 | 2024-02-23 | 广东唯仁医疗科技有限公司 | Multifunctional eye parameter measurement method and device and computer storage medium |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6768747B2 (en) | Two-dimensional confocal imaging using OCT light source and scanning optics | |
| CN110013212B (en) | Multi-parameter and multi-functional eye measurement instrument based on optical coherence tomography | |
| EP1827206B1 (en) | Interference apparatus and method and probe | |
| CN210871522U (en) | Multifunctional ophthalmologic measuring system | |
| CN102283635B (en) | Dual-channel full-hole optical coherence tomography imaging system and formation method | |
| JP5679630B2 (en) | Optical tomographic imaging apparatus and method | |
| CN111671391B (en) | Optical coherence tomography imaging device and imaging method | |
| CN104188625A (en) | Multimodal microscopic imaging system | |
| JP2016209182A (en) | Imaging device, method for operating imaging device, information processor, and method for operating information processor | |
| CN215687754U (en) | SD-OCT whole-eye imaging system | |
| US9918628B2 (en) | Accommodation function evaluation apparatus | |
| CN111643048A (en) | Micro-focusing-based ophthalmologic measurement system and measurement method thereof | |
| CN210130811U (en) | Multi-parameter and multi-functional eye measuring instrument based on optical coherence tomography | |
| CN106308744A (en) | Handheld human body any surface position skin frequency sweeping optical coherence tomography imaging apparatus | |
| RU184084U1 (en) | The device of an endoscopic probe for optical coherence tomography | |
| JP4892719B2 (en) | Fault measurement device and fault measurement method | |
| CN112244760A (en) | Imaging device for realizing function of anterior segment OCT integrated biological measuring instrument based on beam splitter prism | |
| KR20120089047A (en) | Dual focusing optical coherence imaging system | |
| CN109691978A (en) | Relevant optical scanning ophthalmoscope towards ocular blood flow fast imaging | |
| CN107233069A (en) | Increase the optical coherence tomography system of focal depth range | |
| CN118078206A (en) | Scanning type fundus defocus distribution interferometry device and measurement method | |
| CN111557637B (en) | Ophthalmic measurement system | |
| CN209733949U (en) | An optical coherence tomography system for measuring eye pulsations | |
| CN209915944U (en) | Portable AO-OCT imaging device | |
| JP2024516068A (en) | Intraoral Optical Coherence Tomography Scanner with Fiber Optic Adapter |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |