CN209778853U - Medicine detects and filters collection fungus and cultivates integrative device - Google Patents
Medicine detects and filters collection fungus and cultivates integrative device Download PDFInfo
- Publication number
- CN209778853U CN209778853U CN201920532842.XU CN201920532842U CN209778853U CN 209778853 U CN209778853 U CN 209778853U CN 201920532842 U CN201920532842 U CN 201920532842U CN 209778853 U CN209778853 U CN 209778853U
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- CN
- China
- Prior art keywords
- filter
- collection
- cup
- liquid
- bin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000003814 drug Substances 0.000 title claims abstract description 31
- 241000233866 Fungi Species 0.000 title claims abstract description 21
- 229940079593 drug Drugs 0.000 title claims abstract description 17
- 239000007788 liquid Substances 0.000 claims abstract description 52
- 238000001914 filtration Methods 0.000 claims abstract description 42
- 241000894006 Bacteria Species 0.000 claims abstract description 29
- 238000002955 isolation Methods 0.000 claims abstract description 23
- 239000012528 membrane Substances 0.000 claims abstract description 21
- 238000007789 sealing Methods 0.000 claims abstract description 20
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims abstract description 16
- 238000001514 detection method Methods 0.000 claims abstract description 15
- 239000001963 growth medium Substances 0.000 claims abstract description 15
- 239000000725 suspension Substances 0.000 claims abstract description 12
- 238000012360 testing method Methods 0.000 claims abstract description 9
- 238000011010 flushing procedure Methods 0.000 claims abstract description 5
- 239000002699 waste material Substances 0.000 claims description 6
- 239000003153 chemical reaction reagent Substances 0.000 claims description 4
- 244000005700 microbiome Species 0.000 abstract description 7
- 238000012258 culturing Methods 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 11
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 5
- 239000001301 oxygen Substances 0.000 description 5
- 229910052760 oxygen Inorganic materials 0.000 description 5
- 230000001954 sterilising effect Effects 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000005374 membrane filtration Methods 0.000 description 2
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 241001148470 aerobic bacillus Species 0.000 description 1
- 229940124350 antibacterial drug Drugs 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The utility model discloses a drug detection, filtration, bacteria collection and culture integrated device, which comprises an isolation operation bin, an operation glove and a bacteria collection filter, wherein the bacteria collection filter comprises a filter bowl, a liquid collection cup, a filter membrane arranged between the filter bowl and the liquid collection cup and a support detachably connected with the liquid collection cup, the top of the inner side of the isolation operation bin is provided with a suspension hook for a test drug, a suspension hook for a flushing bag and a suspension hook for a culture medium bag, the upper end of the filter bowl is provided with a sealing cover, and the sealing cover is provided with a liquid inlet; an ozone device and a vacuum pump are arranged outside the isolated operation bin. The utility model discloses can filter the collection fungus to the test drug through filtering album fungus ware to can also introduce the filter cup with the culture medium after filtering and cultivate the microorganism, thereby will filter collection fungus and cultivate integratively, need not shift filtration membrane again after filtering collection fungus, thereby can simplify detection operation. And the operations of filtering and collecting bacteria and culturing bacteria are carried out in an isolation operation bin, so that the detection result can be prevented from being influenced by pollution.
Description
Technical Field
The utility model relates to a microbiological detection technical field, in particular to filter collection fungus and cultivate integrative device.
Background
Microbial contamination is one of the main causes of adverse drug events, prevents contaminated drugs from flowing into the market, and has great significance for guaranteeing the life safety of patients. The membrane filtration technology is an important technology for attaching and collecting microorganisms in the field of drug microorganism inspection. For the drugs with antibacterial activity, a membrane filtration method is needed to fully eliminate the antibacterial activity of the drugs so as to facilitate the recovery, reproduction and detection of microorganisms in dormant or damaged states in the drugs.
the existing filtering bacteria collector needs to transfer a filtering membrane into a culture medium for culture after filtering and collecting bacteria for a test drug, the operation process is complex, the filtering and transferring processes are carried out in an open space, and bacteria are easily introduced into the operation process to cause the pollution problem.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model aims at providing a medicine detects filters collection fungus and cultivates integrative device to solve current filtration album fungus ware and need shift filtration membrane to the matrix after filtering collection fungus and cultivate, the manipulation is complicated, and filters and shift process and go on in open space, introduces the bacterium easily in the operation process and causes the pollution problem.
the utility model discloses a medicine detecting, filtering, bacteria collecting and culturing integrated device, which comprises an isolation operation bin consisting of a bin body and a bin door, wherein the bin body or the bin door is provided with an operating hand inlet, and the operating hand inlet is connected with an operating glove;
a bacteria collection filter is arranged in the isolation operation bin and comprises a filter cup, a liquid collection cup, a filter membrane arranged between the filter cup and the liquid collection cup and a support detachably connected with the liquid collection cup, an annular groove is formed in the opening of the liquid collection cup, the filter membrane is arranged in the annular groove, the top surface of the filter membrane is higher than the end surface of the annular groove, and a liquid discharge port is formed in the bottom of the liquid collection cup; the bottom of the filter cup is provided with an inner spigot matched with the mouth of the liquid collecting cup, the inner spigot is in threaded connection with the mouth of the liquid collecting cup, and the bottom of the inner spigot is pressed on the edge of the filter membrane to form a sealing structure under the connection state of the inner spigot and the mouth of the liquid collecting cup;
A test reagent suspension hook, a flushing bag suspension hook and a culture medium bag suspension hook are arranged at the top of the inner side of the isolation operation bin, a sealing cover is arranged at the upper end of the filter cup, and a liquid inlet is formed in the sealing cover;
The drug detection, filtration, collection and culture integrated device also comprises a drainage tube, wherein the drainage tube comprises a tube body, a puncture needle arranged at one end of the tube body and a sealing joint arranged at the other end of the tube body and used for being sleeved on the liquid inlet;
the medicine detection, filtration, collection and culture integrated device also comprises an ozone device and a vacuum pump which are arranged outside the isolated operation bin; the ozone device is connected with the isolation operation bin through an air pipe and is used for inputting ozone into the isolation operation bin; the vacuum pump is connected with a waste liquid bottle through a pipe, and the waste liquid bottle is connected with a liquid outlet at the bottom of the liquid collecting cup through a pipe;
The isolation operation cabin is also provided with an air inlet, and the air inlet is provided with a bacteria filter.
further, still be provided with the air inlet on the sealed lid, be provided with sealed cap on the air inlet.
The utility model has the advantages that:
1. The utility model discloses medicine detects and filters collection fungus and cultivates integrative device, it can filter collection fungus to the test drug through filtering collection fungus ware to can also introduce the filter cup with the culture medium after filtering and cultivate the microorganism, thereby will filter collection fungus and cultivate integratively, need not shift filtration membrane again after filtering collection fungus, thereby can simplify the check out test operation.
2. the utility model discloses medicine detects filters collection fungus and cultivates integrative device, and it can carry out ozone sterilization to keeping apart the operation storehouse, and filters collection fungus and bacteria cultivation operation and all go on in keeping apart the operation storehouse, can avoid open operation to introduce the problem that the bacterium caused the pollution, can improve the accuracy that detects.
Drawings
FIG. 1 is a schematic structural diagram of an integrated device for filtration, collection and cultivation of drug detection in one embodiment;
FIG. 2 is a schematic structural view of an isolation operation bin;
FIG. 3 is a schematic view of the bacteria-collecting filter.
Detailed Description
The invention is further described with reference to the following figures and examples.
as shown in the figure, the medicine detection, filtration, bacteria collection and cultivation integrated device comprises an isolation operation bin 1 consisting of a bin body 101 and a bin door 102, wherein an operating hand inlet 2 is arranged on the bin body or the bin door, and an operating glove 3 is connected to the operating hand inlet.
The isolation operation storehouse is internally provided with a bacteria collection filter, the bacteria collection filter comprises a filter bowl 4, a liquid collection cup 5, a filter membrane 6 arranged between the filter bowl and the liquid collection cup and a support 7 detachably connected with the liquid collection cup, in the embodiment, the bottom of the liquid collection cup is provided with a rectangular insertion rod 8, and the liquid collection cup is inserted on the support through the rectangular insertion rod, so that the assembly and disassembly are convenient. An annular groove is formed in the opening of the liquid collecting cup, the filtering membrane is arranged in the annular groove, the top surface of the filtering membrane is higher than the end surface of the annular groove, and a liquid outlet 9 is formed in the bottom of the liquid collecting cup; the bottom of filter bowl sets up and collects liquid cup oral area complex tang in, tang and the oral area threaded connection of collection liquid cup in, and under tang and the oral area connected state of collection liquid cup including, the bottom of tang presses and forms seal structure on filtration membrane's limit portion, can avoid the problem that liquid flows from the fit clearance in filtering process.
the top of the inner side of the isolation operation bin is provided with a reagent suspension hook 10, a flushing bag suspension hook 11 and a culture medium bag suspension hook 12, the upper end of the filter cup is provided with a sealing cover 13, and the sealing cover is provided with a liquid inlet 14.
The medicine detects and filters collection fungus and cultivates integrative device and still includes drainage tube 15, the drainage tube includes body 151, sets up pjncture needle 152 in body one end and sets up the sealing joint 153 that is used for the cover on the inlet at the body other end.
The medicine detection, filtration, collection and culture integrated device also comprises an ozone device 16 and a vacuum pump 17 which are arranged outside the isolated operation bin; the ozone device is connected with the isolation operation bin through an air pipe and is used for inputting ozone into the isolation operation bin; the vacuum pump is connected with a waste liquid bottle 18 through a pipe, and the waste liquid bottle is connected with a liquid outlet at the bottom of the liquid collecting cup through a pipe;
the isolation operation cabin is also provided with an air inlet, and the air inlet is provided with a bacteria filter 19.
the operation process of the integrated device for detecting, filtering, collecting and culturing the medicines is as follows:
The first step is as follows: hanging the test reagent, the flushing bag and the culture medium bag on corresponding hooks in the isolation operation bin;
secondly, closing a bin door, starting an ozone device to input ozone into the bin, and sterilizing the bin by using the ozone;
Thirdly, after the sterilization treatment, starting a vacuum pump to pump out the gas in the bin so as to eliminate the ozone in the bin, wherein in other processes of pumping out the gas in the bin, the outside air can enter the bin through a bacterial filter on the isolation operation bin, and the air entering the bin is clean and sterile due to the filtering action of the bacterial filter;
and fourthly, putting the two hands of an operator into the operating gloves for operation, connecting the sealing joint at one end of the drainage tube with the liquid inlet, piercing the puncture needle at the other end of the drainage tube into the test medicine bag, and then starting the vacuum pump to enable the two sides of the filtering membrane to form pressure difference so as to realize negative pressure filtering.
And fifthly, after the filtration is finished, the puncture needle is punctured into the washing bag to wash the filtration membrane so as to eliminate the influence of the antibacterial drugs on the microorganisms.
And sixthly, the puncture needle is punctured into the culture medium bag, the culture medium is introduced into the filter cup, and bacteria on the filter membrane are propagated and grown in the culture medium.
In the embodiment, the medicine detection, filtration and bacteria collection and culture integrated device can filter and collect bacteria for the tested medicine through the filtration bacteria collector, and can also introduce a culture medium into the filter cup to culture microorganisms after filtration, so that the filtration bacteria collection and culture are integrated, and a filtration membrane is not required to be transferred after the filtration bacteria collection, thereby simplifying the detection operation.
The medicine detects and filters an album fungus and cultivates integrative device in this embodiment, and it can carry out ozone sterilization to keeping apart the operation storehouse, and filters album fungus and bacteria cultivation operation and all go on in keeping apart the operation storehouse, can avoid open operation to introduce the problem that the bacterium caused the pollution, can improve the accuracy that detects.
As a modification of the above embodiment, the sealing cover is further provided with an air inlet 20, and the air inlet is provided with a sealing cap 21. For aerobic bacteria, more dissolved oxygen in the culture medium is needed in the culture process, and the air inlet is arranged on the sealing cover, so that oxygen in the air can enter the filter cup to increase the dissolved oxygen in the culture medium. For anaerobic bacteria, the dissolved oxygen in the culture medium needs to be reduced in the culture process, and the air inlet is sealed by the sealing cap, so that the oxygen in the air can be reduced from entering the filter bowl.
finally, although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the present invention can be modified or replaced by other means without departing from the spirit and scope of the present invention, which should be construed as limited only by the appended claims.
Claims (2)
1. The utility model provides a medicine detects filters collection fungus and cultivates integrative device which characterized in that: the device comprises an isolated operation bin consisting of a bin body and a bin door, wherein an operating hand inlet is formed in the bin body or the bin door, and operating gloves are connected to the operating hand inlet;
a bacteria collection filter is arranged in the isolation operation bin and comprises a filter cup, a liquid collection cup, a filter membrane arranged between the filter cup and the liquid collection cup and a support detachably connected with the liquid collection cup, an annular groove is formed in the opening of the liquid collection cup, the filter membrane is arranged in the annular groove, the top surface of the filter membrane is higher than the end surface of the annular groove, and a liquid discharge port is formed in the bottom of the liquid collection cup; the bottom of the filter cup is provided with an inner spigot matched with the mouth of the liquid collecting cup, the inner spigot is in threaded connection with the mouth of the liquid collecting cup, and the bottom of the inner spigot is pressed on the edge of the filter membrane to form a sealing structure under the connection state of the inner spigot and the mouth of the liquid collecting cup;
A test reagent suspension hook, a flushing bag suspension hook and a culture medium bag suspension hook are arranged at the top of the inner side of the isolation operation bin, a sealing cover is arranged at the upper end of the filter cup, and a liquid inlet is formed in the sealing cover;
the drug detection, filtration, collection and culture integrated device also comprises a drainage tube, wherein the drainage tube comprises a tube body, a puncture needle arranged at one end of the tube body and a sealing joint arranged at the other end of the tube body and used for being sleeved on the liquid inlet;
the medicine detection, filtration, collection and culture integrated device also comprises an ozone device and a vacuum pump which are arranged outside the isolated operation bin; the ozone device is connected with the isolation operation bin through an air pipe and is used for inputting ozone into the isolation operation bin; the vacuum pump is connected with a waste liquid bottle through a pipe, and the waste liquid bottle is connected with a liquid outlet at the bottom of the liquid collecting cup through a pipe;
The isolation operation cabin is also provided with an air inlet, and the air inlet is provided with a bacteria filter.
2. The integrated device for drug detection, filtration, bacteria collection and culture according to claim 1, wherein: the sealing cover is further provided with an air inlet, and a sealing cap is arranged on the air inlet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920532842.XU CN209778853U (en) | 2019-04-18 | 2019-04-18 | Medicine detects and filters collection fungus and cultivates integrative device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920532842.XU CN209778853U (en) | 2019-04-18 | 2019-04-18 | Medicine detects and filters collection fungus and cultivates integrative device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209778853U true CN209778853U (en) | 2019-12-13 |
Family
ID=68803133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920532842.XU Expired - Fee Related CN209778853U (en) | 2019-04-18 | 2019-04-18 | Medicine detects and filters collection fungus and cultivates integrative device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209778853U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116617434A (en) * | 2023-05-12 | 2023-08-22 | 苏州苏大卫生与环境技术研究所有限公司 | Automatic disinfection effect verification system capable of reusing medical equipment |
-
2019
- 2019-04-18 CN CN201920532842.XU patent/CN209778853U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116617434A (en) * | 2023-05-12 | 2023-08-22 | 苏州苏大卫生与环境技术研究所有限公司 | Automatic disinfection effect verification system capable of reusing medical equipment |
| CN116617434B (en) * | 2023-05-12 | 2024-08-30 | 苏州苏大卫生与环境技术研究所有限公司 | Automatic disinfection effect verification system capable of reusing medical equipment |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20191213 Termination date: 20200418 |