CN208448217U - A kind of anti-bacterial hydrogel dressing - Google Patents
A kind of anti-bacterial hydrogel dressing Download PDFInfo
- Publication number
- CN208448217U CN208448217U CN201720862881.7U CN201720862881U CN208448217U CN 208448217 U CN208448217 U CN 208448217U CN 201720862881 U CN201720862881 U CN 201720862881U CN 208448217 U CN208448217 U CN 208448217U
- Authority
- CN
- China
- Prior art keywords
- layer
- hydrogel
- antibacterial
- dressing
- fixing belt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Materials For Medical Uses (AREA)
Abstract
The utility model relates to a kind of anti-bacterial hydrogel dressings; belong to aerogel dressing field; the anti-bacterial hydrogel dressing includes separation layer, hydrogel layer and protective layer; each fixed bonding in the both ends of the separation layer has fixing belt; the tail end lower surface of the fixing belt is provided with miniature sucker; it is multi-pore channel structure inside the hydrogel layer, antimicrobial nano particle is distributed in duct.The dressing can play the role of antibacterial anti-inflammatory, while reaching sustained drug release effect, drug can be embedded in hydrogel according to different situations, and preferably to promote wound healing, processing wound is convenient and efficient.The setting of separation layer can effectively prevent bacterium, dust intrusion；The problems such as fixing belt and miniature sucker have good gas permeability, instead of the fixed mode of traditional gauze, avoid the poor air permeability of gauze, easy harbor bacteria.Dressing effect harmless to the human body is, it can be achieved that quick repairing effect, the application prospect in fields such as biological medicines are very wide.
Description
Technical field
The utility model relates to aerogel dressing fields, and in particular to a kind of anti-bacterial hydrogel dressing.
Background technique
Hydrogel is a kind of hydrophilic tridimensional network high molecular polymer, can be swollen in water, absorb and protect
Large quantity of moisture is held, and is not dissolved in water, is still able to maintain its shape after reaching swelling equilibrium.Hydrogel wound dressing is to develop recently
, there is good quality and thirst for obtaining widely used new pattern compress afterwards with prospect.
Hydrogel as medical dressing, can wound coverage mouth, realize quickly healing.Gel film bonds postoperative as barrier
Wound, convenient for the formation of pre- preventing thrombosis.Gel has and relatively soft as dressing, and elasticity is good, can slow down pain, organizes phase
Capacitive is good, will not bond wound, bring secondary damage when can be reduced more change dressings；A large amount of wound infiltrations can be absorbed, avoid creating
Wound and Dressing Room hydrops, have the function of certain resistance bacterial invasion, reduce wound face infection；Air-and water-permeable keep granulation and
The normal growth of epithelial tissue promotes wound face healing to leave no trace；And transparent easy observation wound recovery situation；It can ensure
The proper moisture environment of wound healing；Low toxicity is even without toxicity；Can mix certain drug in manufacturing process, when use
Surface of a wound local sustained release is to achieve the effect that long-acting treatment.But at present aerogel dressing have the shortcomings that one it is important, in clinic
The ability of discovery absorption wound exudate is lower during upper use.
Application No. is 201120430359.4 utility model patents to disclose " a kind of novel hydrogel scar patch ", by
Supporting layer, hydrogel layer and separation layer composition, it is characterised in that hydrogel layer is coated on supporting layer, and the hydrogel layer other side is covered
Lid separation layer, hydrogel scar plaster is disposable, safety and sanitation；Hydrogel scar plaster good biocompatibility, not will lead to trouble
Person sticks position allergy；Subject hydrogel scar plaster can take off patch repeatedly, be conducive to local observation in this way.
It discloses application No. is 201610259364.0 utility model patent " a kind of dressing for skin and preparation method thereof ",
It is characterized in that, dressing for skin using bacteria cellulose as substrate, has skin contact surface and conductive surface；The skin contact
The conductivity on surface is less than 10-5S/cm, contains 2 μ g/cm2~20 μ g/cm2Drug, the conductive surface contains 5mg/cm2~
50mg/cm2Conductive material, the conductive material be one of conducting polymer or electrical-conductive nanometer material or a variety of；It is described
Skin contact surface is repaired for directly contact skin with the wound to skin, and the conductive surface is used for on-load voltage,
To control the rate of release of the drug of skin contact surface, while for simulating biological endogenous electric field, promote wound healing indirectly.
In dressing for skin of the invention, conductive surface is combined closely with skin contact surface, thus more can simulated skin injury region it is interior
Source electric field, it is more convenient to use.
It is directed to above-mentioned aerogel dressing, how during dressing use to play antibacterial anti-inflammatory, it is slow to reach drug
While releasing effect, convenient and efficient processing wound effectively heals a wound；On the other hand, it finds novel fixed form and replaces tradition
The problems such as poor air permeability of fixed gauze, easy harbor bacteria is problem to be solved in the utility model.
Summary of the invention
The utility model is to solve the problems, such as appeared in background technique, and solution is as described below:
A kind of anti-bacterial hydrogel dressing, including separation layer, hydrogel layer and protective layer, the protective layer package are covered in
The bottom edge and side of hydrogel layer, the upper layer of the hydrogel layer, which pastes, is bonded with separation layer；The both ends of the separation layer are respectively set
It is equipped with fixing belt, it is multi-pore channel structure inside the hydrogel layer that the tail end lower surface of the fixing belt, which is provided with miniature sucker,
Antimicrobial nano particle is distributed in the duct.
Preferably, the separation layer is air-permeable anti-bacterial gel material.
It is highly preferred that the separation layer is made of chitosan and preservative mixing.
Preferably, the separation layer and fixing belt pass through glue bonding or hot melt adhesive fixed bonding.
Preferably, the fixing belt is an integral molding structure with miniature sucker.
The fixing belt is prepared with miniature sucker by mold integrated molding.
The miniature sucker is by adsorbing skin surface, during being strained and fixed to both ends with fixed absorption skin
Dressing is fixed on skin surface.It is highly preferred that the fixing belt and miniature sucker are bacteria cellulose material.
Preferably, the hydrogel layer is made of gamma-polyglutamic acid and ethylene glycol diglycidylether mixing.
Preferably, the bottom edge of the hydrogel layer is planar structure or is sunk structure to separation layer direction.
Preferably, the porosity of the hydrogel layer is 50%-80%, average Kong Rongwei 0.003-0.010cc/g.
Preferably, the antimicrobial nano uniform particle is distributed in duct.
Preferably, the antimicrobial nano particle diameter is equal to or more than channel diameter.
Preferably, the antimicrobial nano particle is nano silver particles.
Preferably, antibacterial film layer is provided between the side and protective layer of the hydrogel layer.
Preferably, the antibacterial film layer is the side table that antibacterial small molecule is adsorbed on to hydrogel layer by way of spraying
Face position.
Preferably, the protective layer is plastic film, and one end of protective layer side is provided with tear opening.
Preferably, the side both ends of the protective layer are each provided with handle.
Preferably, the handle is bonded by glue or hot melt adhesive is fixedly connected with protective layer.
Preferably, the material of the handle is non-woven fabrics.
When the hydrogel layer ingress of air, absorbs vapor and slight swelling occurs, in the presence of big quantity of fluid
Strong swelling occurs, thus, with the slow expansion of hydrogel layer internal gutter, release antimicrobial nano particle.
The protective layer has the function of completely cutting off outside air and bacterium, be torn when in use.
The utility model bring beneficial effect has:
1, the anti-bacterial hydrogel dressing of the utility model is during application, in numerous small ducts of hydrogel layer
It is uniform-distribution with antimicrobial nano particle, in Hydrogel contact air, vapor is absorbed and slight swelling occurs, in contact wound
In the process, strong swelling, hydrogel internal gutter expansion, to slowly release occur during hydrogel layer contact wound hydrops
Antimicrobial nano particle is released, achievees the effect that antibacterial small molecule is sustained.
2, the setting of separation layer can effectively prevent anti-bacterial hydrogel dressing during treating wound, and bacterium, dust etc. are fallen into
On hydrogel layer；The setting of protective layer can guarantee that during preservation, it is existing to reduce swelling of hydrogel etc. for anti-bacterial hydrogel dressing
As, while protecting anti-bacterial hydrogel dressing from the pollution of dust and bacterium etc..
3, the setting of fixing belt and miniature sucker avoids the ventilative of gauze instead of the fixed mode of traditional gauze
Property it is poor, the problems such as easy harbor bacteria, material bacteria cellulose not only has good toughness, and stationarity is preferable, and spacing
Gas permeability, biocompatibility and degradability.
4, the handle at protective layer side both ends, it is convenient when dressing is taken, it is only necessary to which that lifting handle can take, and avoid whole
Pollution or unexpected disrepair phenomenon caused by dressing when hand is taken,
5, match the water-setting being combined by preferred gamma-polyglutamic acid, ethylene glycol diglycidylether and nano silver particles
Glue-line can effectively inhibit bacterial growth and kill bacterium, ideal recovery effects be obtained on wound model, recovery time is more
It is short, and preventing from scar, the dressing good biocompatibility, effect harmless to the human body limit smaller in biological medicine application.Simultaneously
The dressing adhesion surface of a wound, replacement aspect, avoids causing secondary damage to the surface of a wound.
For nano silver particles in wound there are when body fluid secretion, easily ionizable goes out silver ion, and it is thin to become sticking for high activity
The antibacterial agent of mycoprotein matter and cell membrane.Silver influences protein synthesis by pretending use with the sulfydryl in bacterial cell
Inhibit duplication with combination DNA base, inhibit the respiratory enzyme of bacterium, and then damage dna function, reaches effective restraining and sterilizing bacteria and make
With.Nano silver particles are directly obtained by the way that Nano silver solution is added not by being restored silver ion to obtain silver ion in invention
It arrives.Particle size is uniform, and reducing agent is not added, avoids addition reaction.It is organically combined by hydrogel and nano silver, as one
Kind moisture treatment dressing, can reach dual restraining and sterilizing bacteria effect, rapidly promotes the healing of the surface of a wound.Material requested is to human body simultaneously
It is harmless, and γ-PGA hydrogel is biodegradable, reduces the destruction to environment.
7, the antibacterial film layer being arranged between the side and protective layer of hydrogel layer can be during treating wound to water-setting
Glue plays antibacterial action, prevents hydrogel layer side from easily causing infecting for microorganism etc. in air surface because exposed.
8, the anti-bacterial hydrogel dressing can effectively inhibit bacterial growth and kill bacterium, be managed on wound model
The recovery effects thought, recovery time is shorter, and preventing from scar.
Detailed description of the invention
Fig. 1 is anti-bacterial hydrogel dressing structure chart；
Fig. 2 is anti-bacterial hydrogel dressing structure chart (having antibacterial film layer, bottom edge is planar structure)；
Fig. 3 is anti-bacterial hydrogel dressing structure chart (having antibacterial film layer, bottom edge is sunk structure)；
Reference name corresponding to each serial number is as follows in figure:
1- separation layer, 2- hydrogel layer, 3- protective layer, 4- handle, 5- fixing belt, the miniature sucker of 6-, the duct 7-, 8- are anti-
Bacterium nanoparticle, 9- tear opening, 10- antibacterial film layer.
Specific embodiment
Present invention will be further explained below with reference to specific examples.It should be understood that these examples be merely to illustrate the present invention and
It is not applicable to limit the scope of the invention, other are any do not violate it is made under spiritual essence and principle of the invention change, modification,
Instead of, combination, simplify, should be equivalent substitute mode, be included within the scope of the present invention.In addition, it should also be understood that,
After reading the content taught by the present invention, those skilled in the art can make various modifications or changes to the present invention, these
Equivalent form is also fallen within the scope of the appended claims of the present application.
1 cross-linking method of embodiment prepares hydrogel layer
(1) preparation of hydrogel pre-polymerization liquid: by homopolymer γ-PGA and crosslinking agent ethylene glycol diglycidylether according to matter
Amount is than 2.0-2.5:1, homogeneous mixing.It is 1-30 μ g/ml antimicrobial nano particle solution that concentration, which is added, into mixing homogeneous solution, is stirred
It mixes, obtains homogeneous anti-bacterial hydrogel pre-polymerization liquid, wherein selected antimicrobial nano particle diameter will be equal to or more than hydrogel hole
The average diameter in road.
(2) preparation of hydrogel layer: hydrogel pre-polymerization liquid is injected in mold, after cross-linking reaction, obtains being crosslinked
Full hydrogel layer.Wherein, the shape of hydrogel layer 2 can be prepared into square, rectangle or circle according to the case where wound surface
Shape etc., hydrogel bottom edge can be plane or the sunk structure on separation layer direction.In hydrogel layer, gamma-polyglutamic acid and second
The crosslinked action of Hexanediol diglycidyl ether makes hydrogel layer have multi-pore channel structure, with the addition of antimicrobial nano particle,
Nanoparticle is evenly distributed in duct.
Hydrogel layer used in following example 2-4 is prepared by embodiment 1.
The structure and composition of 2 anti-bacterial hydrogel dressing of embodiment
Reference book attached drawing 1, a kind of anti-bacterial hydrogel dressing, including separation layer 1, hydrogel layer 2 and protective layer 3,
Protective layer 3 wraps up the bottom edge and side for being covered in hydrogel layer 2, and the upper layer of hydrogel layer 2, which pastes, is bonded with separation layer 1；Isolation
Each fixed bonding in both ends of layer 1 has a fixing belt 5, and the tail end lower surface of fixing belt 5 is provided with miniature sucker 6, inside hydrogel layer 2
For 7 structure of multi-pore channel, antimicrobial nano particle 8 is distributed in duct 7.Wherein, fixing belt 5 and miniature sucker 6 are integrally formed knot
Structure；8 diameter of antimicrobial nano particle is equal to or more than 7 diameter of duct.
The structure and composition of 3 anti-bacterial hydrogel dressing of embodiment
Reference book attached drawing 2, a kind of anti-bacterial hydrogel dressing, including separation layer 1, hydrogel layer 2, protective layer 3 and
Antibacterial film layer 10.The upper layer of hydrogel layer 2, which pastes, is bonded with separation layer 1；The both ends of separation layer 1 pass through hot melt adhesive fixed bonding
There is fixing belt 5, the tail end lower surface of fixing belt 5 is provided with miniature sucker 5-15, is 7 knot of multi-pore channel inside hydrogel layer 2
Antimicrobial nano particle 8 is distributed in duct 7 in structure；Protective layer 3 wraps up the bottom edge and side for being covered in hydrogel layer 2, protective layer 3
Side both ends fixed bonding have handle 4；Antibacterial film layer 10 is provided between the side and protective layer 3 of hydrogel layer 2.
Wherein, separation layer 1 is made of chitosan and preservative mixing, and with a thickness of 1-5mm, preservative is that mass ratio is 1:
2 nisin and epsilon-polylysine, the additive amount in chitosan are 0.05%.
Wherein, fixing belt 5 is prepared with miniature sucker 6 by mold integrated molding, and fixing belt 5 is with miniature sucker 6
Bacteria cellulose material, fixing belt 5 with a thickness of 1-3mm, the bottom end of each fixing belt 5 is provided with 5 miniature suckers 6.It is fixed
The specific preparation step of band are as follows: acetobacter xylinum seed liquor is poured into fixing belt and the integrally formed mold of miniature sucker, it is permanent
28 DEG C of stationary culture 72h of temperature to get arrive fixing belt 5.
Wherein, the bottom edge of hydrogel layer 2 is planar structure, hydrogel layer with a thickness of 2-15mm, by gamma-polyglutamic acid and
The homogeneous solution and Nano silver solution composition of ethylene glycol diglycidylether mixing.
Wherein, antibacterial film layer is the side edge surface position for antibacterial small molecule to be adsorbed on to hydrogel layer by way of spraying
It sets.Antibacterial small molecule is biologic antibiotic peptide substance.
The porosity of hydrogel layer 2 is 73.2%, average Kong Rongwei 0.004cc/g, 8 diameter of antimicrobial nano particle be equal to or
Greater than 7 diameter of duct.
Antimicrobial nano particle 8 is evenly distributed in duct 7, and antimicrobial nano particle 8 is nano silver particles.
Protective layer 3 is plastic film, and with a thickness of 0.1-0.5mm, one end of protective layer 3 is provided with tear opening 9, protective layer 3
The material of the handle 4 at both ends is non-woven fabrics.
In anti-bacterial hydrogel dressing use process, the handle 4 at dressing both ends is lifted, to take dressing.Pass through tearing
Mouthfuls 9 will have the protective layer 3 of isolation outside air and bacterial action tear, and bacterium aerogel dressing is affixed on wound affected part, will be every
The fixing belt 5 at 1 both ends of absciss layer is straightened, and the fixation of miniature sucker 6 of 5 tail end of fixing belt is adsorbed in skin surface.
When 2 ingress of air of hydrogel layer of anti-bacterial hydrogel dressing, absorbs vapor and slight swelling occurs, in contact wound
Hydrops during, hydrogel layer 2 occurs to be swollen strongly, 2 internal gutter of hydrogel layer expansion, to release antimicrobial nano grain
Son 8.After sticking certain period of time, miniature sucker 6 is unpluged, replaces antiseptic dressing.
The structure and composition of 4 anti-bacterial hydrogel dressing of embodiment
Reference book attached drawing 3, reference book attached drawing 2, a kind of anti-bacterial hydrogel dressing, including separation layer 1, hydrogel
Layer 2, protective layer 3 and antibacterial film layer 10.The upper layer of hydrogel layer 2, which pastes, is bonded with separation layer 1；The both ends of separation layer 1 pass through
Hot melt adhesive fixed bonding has fixing belt 5, and the tail end lower surface of fixing belt 5 is provided with miniature sucker 6, is inside hydrogel layer 2
Antimicrobial nano particle 8 is distributed in duct 7 in 7 structure of multi-pore channel；Protective layer 3 wraps up the bottom edge and side for being covered in hydrogel layer 2
The side both ends fixed bonding on side, protective layer 3 has handle 4；Antibacterial film is provided between the side and protective layer 3 of hydrogel layer 2
Layer 10.
Wherein, separation layer 1 is air-permeable anti-bacterial gel material, with a thickness of 5mm.
Fixing belt 5 is prepared with miniature sucker 6 by mold integrated molding, and fixing belt 5 and miniature sucker 6 are bacterium
Cellulose material, miniature sucker 6 are 5-15, and fixing belt 5 is with a thickness of 3mm.
Wherein, the bottom edge of hydrogel layer 2 is the sunk structure to separation layer direction, and the sunk structure is especially suitable for human body
Four limbs area skin, the gel dressing can be made preferably to be bonded skin.Hydrogel layer 2 is with a thickness of 15mm；Hydrogel layer 2
The homogeneous solution and Nano silver solution mixed by gamma-polyglutamic acid and ethylene glycol diglycidylether forms.
The porosity of hydrogel layer 2 is 76%, average Kong Rongwei 0.008cc/g, and 8 diameter of antimicrobial nano particle is equal to or greatly
In 7 diameter of duct, antimicrobial nano particle 8 is evenly distributed in duct 7；Wherein, antimicrobial nano particle 8 is nanometer zinc particles.
Wherein, antibacterial film layer is that antibacterial small molecule is adsorbed on to the side edge surface position of hydrogel layer by way of spraying
It sets.Antibacterial small molecule is biologic antibiotic peptide substance.
Protective layer 3 is plastic film, one end of protective layer 3 is provided with tear opening 9, the material of handle 4 with a thickness of 0.5mm
For non-woven fabrics.
The control experiment of 5 dressing of embodiment
The dressing of control group and experimental group is applied in wound respectively, observes wound healing situation, wherein control group 1:
Gauze；Control group 2: the hydrogel layer in aerogel dressing changes the hydrogel layer of no antibacterial nanoparticle into；Experimental group: this implementation
Anti-bacterial hydrogel dressing in example 2.
The protective layer 3 of hydrogel antimicrobial dressing is torn, aerogel dressing is covered on wound, by consolidating for dressing both ends
Determine band 5 to be straightened, the fixation of miniature sucker 6 is adsorbed in skin surface, after pasting certain period of time, unplugs miniature sucker 6, replacement is anti-
Bacterium dressing checks wound recovery in different time sections, wound recovery rate is calculated, wherein antimicrobial nano silver concentration is
20.0 μ g/ml homogeneous pre-polymerization liquid.
Selected experimental animal is mouse, and gender is male, and weight 18-40g, the age is 5-9 weeks.After mouse species
Back carries out artificial 1cm × 1cm modeling, anti-bacterial hydrogel dressing is pasted wound, 48h replaces hydrogel, checks that wound is extensive daily
Multiple situation, on day 4, is calculated wound recovery rate in 7 days, 10 days, 14 days.Wherein, control group 1, control group 2 and experimental group
Recovery rate respectively reaches 4.45%, 13.15%, 27.36% on day 4 for dressing；7th day recovery rate respectively reach 8.34%,
19.56%, 48.61%；Recovery rate respectively reaches 28.27%, 51.66%, 71.33% within 10th day；14th day recovery rate difference
Reach 41.34%, 63.84%, 80.21%.
Specific embodiment of the utility model is described in detail above, but content is only the preferable of the utility model
Embodiment should not be considered as limiting the scope of the present invention.It is made according to the scope of application of this utility model equal
Deng variation and improvement etc., should still belong within the patent covering scope of the utility model.
Claims (10)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720862881.7U CN208448217U (en) | 2017-07-17 | 2017-07-17 | A kind of anti-bacterial hydrogel dressing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720862881.7U CN208448217U (en) | 2017-07-17 | 2017-07-17 | A kind of anti-bacterial hydrogel dressing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208448217U true CN208448217U (en) | 2019-02-01 |
Family
ID=65139438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720862881.7U Active CN208448217U (en) | 2017-07-17 | 2017-07-17 | A kind of anti-bacterial hydrogel dressing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208448217U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125712A (en) * | 2018-09-26 | 2019-01-04 | 南阳市中心医院 | A kind of burned infants scald anesthesia dressing patch |
| CN110786989A (en) * | 2019-10-28 | 2020-02-14 | 安庆师范大学 | A kind of preparation method of medical antibacterial gel dressing |
| CN111228387A (en) * | 2019-10-22 | 2020-06-05 | 成都六然医疗科技有限公司 | Cold compress gel for relieving gout and preparation method thereof |
| CN115040321A (en) * | 2022-08-17 | 2022-09-13 | 上海大博医疗科技有限公司 | Portable dressing |
-
2017
- 2017-07-17 CN CN201720862881.7U patent/CN208448217U/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125712A (en) * | 2018-09-26 | 2019-01-04 | 南阳市中心医院 | A kind of burned infants scald anesthesia dressing patch |
| CN111228387A (en) * | 2019-10-22 | 2020-06-05 | 成都六然医疗科技有限公司 | Cold compress gel for relieving gout and preparation method thereof |
| CN110786989A (en) * | 2019-10-28 | 2020-02-14 | 安庆师范大学 | A kind of preparation method of medical antibacterial gel dressing |
| CN110786989B (en) * | 2019-10-28 | 2021-06-11 | 安庆师范大学 | Preparation method of medical antibacterial gel dressing |
| CN115040321A (en) * | 2022-08-17 | 2022-09-13 | 上海大博医疗科技有限公司 | Portable dressing |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN208448217U (en) | A kind of anti-bacterial hydrogel dressing | |
| CN102552964B (en) | Nano silver chitosan composite antibacterial composition, adhesive bandage and preparation method of adhesive bandage | |
| CN112300420A (en) | An injectable antibacterial interpenetrating double network hydrogel and its preparation method and application | |
| JPH0614956B2 (en) | Hydrophilic biopolymer copolyelectrolite | |
| JP2022523780A (en) | Antibacterial dressings, dressing components, and methods | |
| CN104383585B (en) | A kind of three-dimensional manometer composite adhesive bandage and preparation and application thereof | |
| CN105833331A (en) | Preparation method for degradable biological wound dressing and obtained product | |
| CN204655268U (en) | A kind of alginate medical dressing | |
| CN101919761A (en) | Medical hydrogel incision dressing and preparation method thereof | |
| CN1136012C (en) | Wound dressing and method for its preparation | |
| CN107617121A (en) | A kind of skin wound biology induced activity dressing and its preparation method and application | |
| Qin | Advanced wound dressings | |
| JP6290184B2 (en) | Wound dressing | |
| WO2017101020A1 (en) | Modified dressing | |
| CN202458927U (en) | Nano-silver antimicrobial self-adhesive tape capable of powerfully sucking pus | |
| CN105288698A (en) | Calcium alginate composite medical surgical dressing and preparation method thereof | |
| CN112656988B (en) | Hydrogel dressing and dressing patch | |
| CN114668885A (en) | Antibacterial healing-promoting functional dressing and preparation method thereof | |
| CN204158771U (en) | A kind of Bacterial cellulose/chitosan composite sponge dressing | |
| CN204072475U (en) | A kind of composite aquogel wound dressing | |
| CN107375994A (en) | A kind of medical gel adhesive bandage product preparation method | |
| RU2240140C2 (en) | Medicinal multilayer bandage and articles based on such bandage | |
| US20120015022A1 (en) | Biodegradable wound care products with biocompatible artificial skin treatment | |
| CN209500357U (en) | A kind of self-adaptation type alginate dressing | |
| CN106178080B (en) | A kind of surgery medical dressing hemostatic adhesive bandage |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |