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CN207725724U - Dextran large biological molecule finished product collects crushing packing system automatically - Google Patents

Dextran large biological molecule finished product collects crushing packing system automatically Download PDF

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Publication number
CN207725724U
CN207725724U CN201721805318.2U CN201721805318U CN207725724U CN 207725724 U CN207725724 U CN 207725724U CN 201721805318 U CN201721805318 U CN 201721805318U CN 207725724 U CN207725724 U CN 207725724U
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pipeline
filter
vacuum
port
valve
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郑睿智
王长海
孙兆永
王琰
李晓芸
孙恒
徐凯
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Shandong Jinlang Bio-Technology Co Ltd
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Shandong Jinlang Bio-Technology Co Ltd
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Abstract

本实用新型属于右旋糖酐生物大分子生产领域,具体涉及右旋糖酐生物大分子成品自动收集粉碎包装系统。本实用新型所述的自动收集粉碎包装系统可实现产品自干燥到包装无外界接触,产品质量提高,洁净度检测指标达到99.5%以上,自动化操作效率高、减低员工劳动量,过程没有粉尘产生,提高收率0.2‑0.3%,减少职业危害,通过平衡阀、调节阀、气动阀的使用,使控制系统更加稳定,员工的工作主要是巡检,减少人员配置3‑5人,减低生产成本,在线清洗、无菌过滤器的使用,提高设备使用寿命,收率提高0.1‑0.3%;成品微生物限度检测100%合格。

The utility model belongs to the field of dextran biomacromolecule production, in particular to a system for automatically collecting and crushing dextran biomacromolecule finished products. The automatic collection, crushing and packaging system described in the utility model can realize that the product has no external contact from drying to packaging, the product quality is improved, the cleanliness detection index reaches more than 99.5%, the automatic operation efficiency is high, the labor load of employees is reduced, and there is no dust in the process. Increase the yield by 0.2-0.3%, reduce occupational hazards, and make the control system more stable through the use of balance valves, regulating valves, and pneumatic valves. The work of employees is mainly patrol inspection, reducing staffing by 3-5 people, and reducing production costs. Online cleaning and the use of sterile filters increase the service life of the equipment and increase the yield by 0.1‑0.3%; the microbial limit test of the finished product is 100% qualified.

Description

右旋糖酐生物大分子成品自动收集粉碎包装系统Dextran biomacromolecule finished product automatic collection, crushing and packaging system

技术领域technical field

本实用新型属于生物大分子生产领域,具体涉及右旋糖酐生物大分子成品自动收集粉碎包装系统。The utility model belongs to the field of biomacromolecule production, in particular to a system for automatically collecting and crushing dextran biomacromolecule finished products.

背景技术Background technique

在生产右旋糖酐生物大分子过程中,需要用到集料包装装置对物料进行收集、输送和包装。在生产过程中我们发现右旋糖酐生物大分子干燥包装过程中存在以下问题:①一般干燥机下料口用袋子或料车接料,存在粉尘产生,存在二次污染;②接出的物料,均需要进行投料后方可进行粉碎,同样存在粉尘产生及劳动强度的问题;③生物大分子存在粘度大、容易吸潮的物料性质,粉碎时物料遇温度升高或环境中空气湿度大物料吸潮,物料容易成胶糕状且附着性极强,所以用粉碎机粉碎速度慢,收率损失大(正常一般损失2-3%),同时胶糕状凝固容后硬度大,极易损坏粉碎机设备;④原工艺环境洁净程度要求高,占地面积大,整套装置包括干燥设备、粉碎混合设备、包装设备均需要建设洁净区方可保证产品质量(特别是微生物限度);⑤在包装过程中产生的粉尘聚集,设备设施上,遇到空气中的水分迅速吸潮变成胶糕状,且清理困难;⑥设备清洁困难,设备、管线内部的清理,应产品特性清理困难。In the process of producing dextran biomacromolecules, a collection and packaging device is required to collect, transport and package the materials. During the production process, we found the following problems in the dry packaging process of dextran biomacromolecules: ①Generally, bags or trucks are used to receive materials at the discharge port of dryers, which will cause dust and secondary pollution; Crushing can only be carried out after feeding, and there are also problems of dust generation and labor intensity; ③biological macromolecules have high viscosity and are easy to absorb moisture. It is easy to form a gelatinous cake and has strong adhesion, so the pulverization speed is slow with a pulverizer, and the yield loss is large (normally, the loss is 2-3%). At the same time, the gelatinous cake has a high hardness after solidification, and it is easy to damage the pulverizer equipment; ④The cleanliness of the original process environment is high and the floor area is large. The whole set of equipment, including drying equipment, crushing and mixing equipment, and packaging equipment, needs to be built in a clean area to ensure product quality (especially the limit of microorganisms); Dust gathers, and on equipment and facilities, when encountering moisture in the air, it quickly absorbs moisture and turns into a gelatinous cake, and it is difficult to clean;

实用新型内容Utility model content

为解决上述问题,本实用新型提供了一种右旋糖酐生物大分子成品自动收集粉碎包装系统,具体技术方案如下:In order to solve the above problems, the utility model provides a system for automatically collecting and crushing the finished dextran biomacromolecule products, and the specific technical scheme is as follows:

右旋糖酐生物大分子成品自动收集粉碎包装系统,包括干燥机,所述干燥机的出料口与粉碎机的进料口连通,所述粉碎机的出料口通过管道与料仓的进料口连接,所述料仓的出料口通过真空上料管道与过滤器的进料口连接,所述过滤器的出料口通过管道与关风机连接,所述关风机与晶体暂存罐的进料口连接,所述晶体暂存罐的出料口通过管道与低温螺旋粉碎机的进料口连接,所述低温螺旋粉碎机的出料口通过真空上料管道与旋风分离器的进料口连接,所述旋风分离器的出料口通过管道与关风机连接,所述关风机与混合罐的进料口连接,所述混合罐的出料口通过管道与振动分筛机的进料口连接,所述振动分筛机的出料口通过管道与上料仓的进料口连接,所述上料仓的出料口通过真空上料管道与旋风分离器的进料口连接,所述旋风分离器的出料口通过管道与包装料仓的进料口连接,所述包装料仓的出料口通过管道与关风机连接,所述关风机与金属探测仪的进料口连接,所述金属探测仪的出料口通过管道与自动包装机连接。Dextran biomacromolecule finished products are automatically collected, pulverized and packaged, including a dryer, the outlet of the dryer is connected to the feed port of the pulverizer, and the discharge port of the pulverizer is connected to the feed port of the silo through a pipeline , the discharge port of the silo is connected with the feed port of the filter through the vacuum feeding pipeline, the discharge port of the filter is connected with the shut-off fan through the pipeline, and the feed shut-off fan and the crystal temporary storage tank The discharge port of the crystal temporary storage tank is connected to the feed port of the low-temperature screw pulverizer through a pipeline, and the discharge port of the low-temperature screw pulverizer is connected to the feed port of the cyclone separator through a vacuum feeding pipeline , the discharge port of the cyclone separator is connected with the blower fan through the pipeline, the blower fan is connected with the feed port of the mixing tank, and the discharge port of the mixing tank is connected with the feed port of the vibrating screen machine through the pipeline , the discharge port of the vibrating sieving machine is connected with the feed port of the upper hopper through a pipeline, and the discharge port of the upper hopper is connected with the feed port of the cyclone separator through a vacuum feeding pipeline, and the cyclone The discharge port of the separator is connected to the feed port of the packaging silo through a pipeline, and the discharge port of the packaging silo is connected to the shut-off fan through a pipeline, and the shut-off fan is connected to the feed port of the metal detector. The discharge port of the metal detector is connected with the automatic packaging machine through a pipeline.

作为优选,所述料仓和过滤器均设置有两个,两个料仓一用一备,所述过滤器为0.22微米无菌钛棒过滤器,所述粉碎机为摆锤式粗粉碎机,摆锤式粗粉碎机可以实现两个料仓的互换进料,所述粉碎机上设置有快开式观察维修孔,随时观察运行情况,若有异常可以打开处理;所述粉碎机与料仓的进料口之间的管道上设置有气动蝶阀,所述料仓的出料口处的管道上设置有气动球阀,所述料仓与过滤器之间的真空上料管道上设置有清洗排放口,所述料仓上设置有震击器、视孔灯和快开式观察孔,震击器设置在料仓的1/3处,可防止粉碎后颗粒堵塞,视孔灯和快开式观察孔便于观察及快速处理异常情况,所述料仓的底部设置有带刹车片的轮子,如需整体更换备用料仓时,拆下推走直接安装备用料仓就行,不会影响进度。As a preference, two silos and two filters are provided, one for use and one for standby, the filter is a 0.22 micron sterile titanium rod filter, and the pulverizer is a pendulum type coarse pulverizer , the pendulum-type coarse pulverizer can realize the interchangeable feeding of the two silos, and the pulverizer is provided with a quick-opening observation and maintenance hole to observe the operation situation at any time, and can be opened for processing if there is any abnormality; the pulverizer and the material A pneumatic butterfly valve is installed on the pipeline between the feed ports of the silo, a pneumatic ball valve is provided on the pipeline at the discharge port of the silo, and a cleaning valve is installed on the vacuum feeding pipeline between the silo and the filter. At the discharge port, the silo is equipped with a jar, a viewing hole lamp and a quick-opening observation hole. The jar is set at 1/3 of the silo to prevent the particles from being clogged after crushing. The type observation hole is convenient for observation and quick handling of abnormal situations. Wheels with brake pads are installed at the bottom of the silo. If you need to replace the spare silo as a whole, just remove it and push it away to install the spare silo directly without affecting the progress.

作为优选,所述料仓上端的真空口通过管道与真空系统连接,所述真空系统包括真空机组,所述真空机组通过管道分别与两组0.01微米的无菌过滤器连接,所述无菌过滤器通过管道分别与料仓上端的真空口连接,所述无菌过滤器的进气口和出气口处的管道上均设置有球阀,所述料仓上端的真空口处的管道上设置有气动气阀,实现真空开启,所述无菌过滤器与料仓之间的管道上设置有真空检测仪和平衡阀,真空检测仪可保持真空度检测、平衡阀可控制整个系统稳定。As a preference, the vacuum port at the upper end of the silo is connected to a vacuum system through a pipeline, and the vacuum system includes a vacuum unit, and the vacuum unit is respectively connected to two sets of 0.01 micron sterile filters through pipelines, and the sterile filter The device is respectively connected to the vacuum port at the upper end of the silo through pipelines, ball valves are provided on the pipelines at the air inlet and outlet of the sterile filter, and pneumatic valves are installed on the pipelines at the vacuum port at the upper end of the silo. The air valve realizes vacuum opening, and the pipeline between the sterile filter and the silo is provided with a vacuum detector and a balance valve, the vacuum detector can maintain vacuum degree detection, and the balance valve can control the stability of the entire system.

作为优选,所述料仓上端的气口通过管道与罗茨风机系统连接,所述罗茨风机系统包括罗茨风机组,所述罗茨风机组通过管道分别与两组0.01微米的无菌过滤器连接,所述无菌过滤器通过管道分别与料仓上端的气口连接,所述无菌过滤器的进气口和出气口处的管道上均设置有球阀,所述料仓上端的气口处的管道上设置有布风阀,实现风的开启,所述无菌过滤器与料仓之间的管道上设置有风量检测仪和平衡阀,风量检测仪保持风量稳定运行、平衡阀控制整个系统稳定。通过真空气动阀、布风阀的开启互换,实现物料输送;通过真空、风的检测、平衡实现稳定运行。As preferably, the air port at the upper end of the silo is connected to the Roots blower system through a pipeline, and the Roots blower system includes a Roots blower unit, and the Roots blower unit is respectively connected with two sets of 0.01 micron sterile filters through pipelines. connected, the sterile filter is respectively connected to the air port at the upper end of the silo through pipelines, ball valves are arranged on the pipelines at the air inlet and the air outlet of the sterile filter, and the air port at the upper end of the silo An air distribution valve is set on the pipeline to realize the opening of the wind. An air volume detector and a balance valve are installed on the pipeline between the sterile filter and the silo. The air volume detector keeps the air volume running stably, and the balance valve controls the stability of the entire system. . Through the opening and interchange of the vacuum pneumatic valve and the air distribution valve, the material transportation is realized; the stable operation is realized through the detection and balance of the vacuum and wind.

作为优选,所述过滤器上端的真空口通过管道与真空机组连接,真空口与真空机组之间的管道上设置有平衡阀和真空检测仪,所述过滤器上端的真空口处设置有气动阀门,通过真空检测探头,当真空上料管道压力大于5万pa,判断过滤器出现堵塞,需要进行清理;所述过滤器上端的风口通过管道与仪表风气源分配装置连接,设定反吹控制间隔时间100-600秒,对钛棒过滤器进行反吹操作。所述仪表风气源分配装置上分别设置有直径4-12mm的仪表风管道、气动阀风管道、平衡阀风管道、直径20-38的反吹风管道,可实现气动阀、平衡阀、吹风阀的开启。As a preference, the vacuum port at the upper end of the filter is connected to the vacuum unit through a pipeline, a balance valve and a vacuum detector are arranged on the pipeline between the vacuum port and the vacuum unit, and a pneumatic valve is provided at the vacuum port at the upper end of the filter , through the vacuum detection probe, when the pressure of the vacuum feeding pipeline is greater than 50,000 pa, it is judged that the filter is clogged and needs to be cleaned; the air outlet at the upper end of the filter is connected to the instrument air source distribution device through the pipeline, and the back blowing control interval is set The time is 100-600 seconds, and the titanium rod filter is backflushed. The instrument air source distribution device is respectively provided with an instrument air pipe with a diameter of 4-12 mm, a pneumatic valve air pipe, a balance valve air pipe, and a reverse blow pipe with a diameter of 20-38 mm, which can realize the operation of the pneumatic valve, balance valve, and blower valve. open.

作为优选,所述晶体暂存罐和混合罐上均设置有视孔灯、罐盖、搅拌装置和保温夹套,罐体下方设过热水进出管道,出水比进水低5-10cm,出水地点设排空阀,所述罐盖上设置有观察孔,所述晶体暂存罐和混合罐的出料口处均设置有电动调节阀,控制出料速度,进粉碎机量控制,电动调节阀通过软连接与低温螺旋粉碎机相连,低温螺旋粉碎机上分别在粉碎机定刀盘、动刀盘上设置有进风过滤器,所述进风过滤器内安装0.45mm预过滤器和0.01mm无菌精过滤器。As a preference, the crystal temporary storage tank and the mixing tank are equipped with a sight hole lamp, a tank cover, a stirring device and a heat preservation jacket, and a superheated water inlet and outlet pipeline is arranged under the tank body, and the outlet water is 5-10 cm lower than the inlet water, and the outlet water An emptying valve is set at the location, an observation hole is set on the tank cover, and an electric regulating valve is set at the discharge port of the crystal temporary storage tank and the mixing tank to control the discharge speed, control the amount of feed into the pulverizer, and electric adjustment The valve is connected with the low-temperature screw grinder through a soft connection. The low-temperature screw grinder is equipped with an air inlet filter on the fixed cutter head and the moving cutter head of the grinder respectively, and a 0.45mm pre-filter and a 0.01mm filter are installed in the air inlet filter. Sterile fine filter.

作为优选,所述旋风分离器上方通过管道与引风机相连,所述引风机通过管道与水幕除尘系统相连,实现尾气处理;所述上料仓内的进料管道进入料仓3-5cm,上料仓内的出料管距离底部3-5cm。As preferably, the top of the cyclone separator is connected to the induced draft fan through a pipeline, and the induced draft fan is connected to the water curtain dust removal system through a pipeline to realize tail gas treatment; The discharge pipe in the upper silo is 3-5cm away from the bottom.

作为优选,所述右旋糖酐生物大分子成品自动收集粉碎包装系统还设置有清洗系统,清洗系统可实现在线清洗,所述清洗系统包括过热水系统和纯水系统,所述过热水系统和纯水系统的出水口通过管道分别与料仓、晶体暂存罐、混合罐、过滤器上的进水口连接,所述过热水系统和纯水系统的出水口处的管道上均设置有球阀,所述料仓、晶体暂存罐、混合罐、过滤器上的进水口处均设置有气动阀,所述料仓、晶体暂存罐、混合罐、过滤器内均设置有喷淋管,喷淋管上设置有喷淋头,喷淋管与进水口连接,所述料仓和过滤器内的喷头为扇形60度喷淋头,所述晶体暂存罐和混合罐内的喷头为360度旋转喷淋头,在晶体暂存罐和混合罐下方的电动调节阀前设排空阀,低温螺旋粉碎机和振动分筛机与旋风分离器连接的管道上设排空阀。清洗是用热水清洗干净后,再用纯化水进行洗涤。As a preference, the system for automatic collection, pulverization and packaging of dextran biomacromolecule finished products is also provided with a cleaning system, which can realize online cleaning, and the cleaning system includes a superheated water system and a pure water system, and the superheated water system and a pure water system The water outlet of the water system is respectively connected to the water inlet on the silo, the crystal temporary storage tank, the mixing tank and the filter through pipelines, and ball valves are arranged on the pipelines at the water outlets of the superheated water system and the pure water system. Pneumatic valves are all arranged at the water inlets of the silo, the crystal temporary storage tank, the mixing tank and the filter, and the spray pipes are all arranged in the said hopper, the crystal temporary storage tank, the mixing tank and the filter. There is a spray head on the shower pipe, and the spray pipe is connected to the water inlet. The spray head in the silo and the filter is a fan-shaped 60-degree spray head, and the spray head in the crystal temporary storage tank and the mixing tank is 360-degree. Rotate the spray head, set an emptying valve in front of the electric regulating valve below the crystal temporary storage tank and the mixing tank, and set an emptying valve on the pipeline connecting the low-temperature screw pulverizer, vibrating sieving machine and cyclone separator. Cleaning is to wash with hot water, and then wash with purified water.

作为优选,还包括控制系统,所述控制系统包括控制器数据通讯系统,所述气动阀、电动调节阀、平衡阀和真空检测仪、风量检测仪均与控制器数据通讯系统电联接,控制器数据通讯系统包括检测仪变送器和气动阀、电动调节阀、平衡阀执行器,所述控制器数据通讯系统与操作微机相连,所述控制系统可以实现现场控制,进一步可以实现电脑联机远程控制。Preferably, it also includes a control system, the control system includes a controller data communication system, the pneumatic valve, electric regulating valve, balance valve, vacuum detector, and air flow detector are all electrically connected to the controller data communication system, and the controller The data communication system includes detector transmitters, pneumatic valves, electric regulating valves, and balance valve actuators. The controller data communication system is connected to the operating microcomputer. The control system can realize on-site control, and further can realize computer online remote control .

本实用新型的有益效果Beneficial effects of the utility model

1、产品自干燥到包装无外界接触,产品质量提高,洁净度检测指标达到99.5%以上。1. The product has no external contact from drying to packaging, the product quality is improved, and the cleanliness detection index reaches more than 99.5%.

2、效率高、减低员工劳动量,过程没有粉尘产生,提高收率0.2-0.3%,减少职业危害。2. High efficiency, reduce the labor load of employees, no dust is generated in the process, increase the yield by 0.2-0.3%, and reduce occupational hazards.

3、通过平衡阀、调节阀、气动阀的使用,使控制系统更加稳定,员工的工作主要是巡检,减少人员配置3-5人,减低生产成本。3. Through the use of balance valves, regulating valves, and pneumatic valves, the control system is more stable. The work of employees is mainly inspections, reducing staffing by 3-5 people and reducing production costs.

4、在线清洗、无菌过滤器的使用,提高设备使用寿命,收率提高0.1-0.3%;成品微生物限度检测100%合格。4. The use of online cleaning and sterile filters can improve the service life of the equipment and increase the yield by 0.1-0.3%; the microbial limit test of the finished product is 100% qualified.

5、本实用新型只需在包装口设立洁净区,其余设备设置在一般生产区就可以,洁净区大幅减少,一般生产区域扩大,生产管理及安全管理级别降低;节约固定投资投入,企业管理更加便利。5. This utility model only needs to set up a clean area at the packaging port, and the rest of the equipment can be set in the general production area. The clean area is greatly reduced, the general production area is expanded, and the level of production management and safety management is lowered; fixed investment investment is saved, and enterprise management is more efficient. convenient.

6、清洗系统用85度热水或蒸汽进行设备、管线内部的清理,产品溶解,清理效果较好,热水清洗干净后,再用纯化水进行洗涤,可以进一步保证清洗的洁净程度。6. The cleaning system uses 85-degree hot water or steam to clean the inside of equipment and pipelines. The product dissolves and the cleaning effect is better. After cleaning with hot water, wash with purified water to further ensure the cleanliness of the cleaning.

附图说明Description of drawings

图1为实施例1的结构示意图。Fig. 1 is the structural representation of embodiment 1.

图中:1:干燥机;2:粉碎机;3:料仓;4:过滤器;5:关风机;6:晶体暂存罐;7:低温螺旋粉碎机;8:旋风分离器;9:混合罐;10:振动分筛机;11:上料仓;12:排空阀 ;13:包装料仓;14:金属探测仪;15:自动包装机;16:快开式观察维修孔;17:震击器;18:视孔灯;19:轮子;20:真空机组;21:无菌过滤器;22:真空检测仪;23:平衡阀;24:清洗排放口;25:罗茨风机组;26:风量检测仪;27:喷淋管;28:喷淋头;29:过热水系统;30:纯水系统;31:仪表风气源分配装置;32:进风过滤器;33:引风机;34:水幕除尘系统。In the figure: 1: dryer; 2: pulverizer; 3: silo; 4: filter; 5: fan off; 6: crystal storage tank; Mixing tank; 10: vibrating sieving machine; 11: feeding bin; 12: emptying valve; 13: packaging bin; 14: metal detector; 15: automatic packaging machine; 16: quick opening observation and maintenance hole; 17 : jar; 18: sight lamp; 19: wheel; 20: vacuum unit; 21: sterile filter; 22: vacuum detector; 23: balance valve; 24: cleaning discharge port; 25: Roots blower unit ;26: Air volume detector; 27: Spray pipe; 28: Spray head; 29: Superheated water system; 30: Pure water system; 31: Instrument air source distribution device; 32: Air inlet filter; fan; 34: water curtain dust removal system.

具体实施方式Detailed ways

下面结合具体实施案例对本实用新型作进一步的描述。The utility model will be further described below in conjunction with specific implementation examples.

实施例 1Example 1

右旋糖酐生物大分子成品自动收集粉碎包装系统,包括干燥机1,所述干燥机1的出料口与粉碎机2的进料口连通,所述粉碎机2的出料口通过管道与料仓3的进料口连接,所述料仓3的出料口通过真空上料管道与过滤器4的进料口连接,所述过滤器4的出料口通过管道与关风机5连接,所述关风机5与晶体暂存罐6的进料口连接,所述晶体暂存罐6的出料口通过管道与低温螺旋粉碎机7的进料口连接,所述低温螺旋粉碎机7的出料口通过真空上料管道与旋风分离器8的进料口连接,所述旋风分离器8的出料口通过管道与关风机连接,所述关风机与混合罐9的进料口连接,所述混合罐9的出料口通过管道与振动分筛机10的进料口连接,所述振动分筛机10的出料口通过管道与上料仓11的进料口连接,所述上料仓11的出料口通过真空上料管道与旋风分离器的进料口连接,所述旋风分离器的出料口通过管道与包装料仓13的进料口连接,所述包装料仓13的出料口通过管道与关风机连接,所述关风机与金属探测仪14的进料口连接,所述金属探测仪14的出料口通过管道与自动包装机15连接。Dextran biomacromolecule finished products are automatically collected, pulverized and packaged, including a drier 1, the discharge port of the drier 1 is connected to the feed port of the pulverizer 2, and the discharge port of the pulverizer 2 is connected to the silo 3 through a pipeline The feed port of the silo 3 is connected with the feed port of the filter 4 through a vacuum feeding pipeline, and the discharge port of the filter 4 is connected with the fan 5 through a pipeline. The blower fan 5 is connected to the feed port of the temporary crystal storage tank 6, and the discharge port of the temporary crystal storage tank 6 is connected to the feed port of the low-temperature screw pulverizer 7 through a pipeline, and the discharge port of the low-temperature screw pulverizer 7 Connect with the feed inlet of cyclone separator 8 by vacuum feeding pipeline, the discharge outlet of described cyclone separator 8 is connected with shut-off fan by pipeline, and described shut-off fan is connected with the feed inlet of mixing tank 9, and described mixing The discharge port of tank 9 is connected with the feed port of vibrating sieving machine 10 by pipeline, and the discharge port of described vibrating sieving machine 10 is connected with the feed port of upper material bin 11 by pipeline, and described upper material bin 11 The discharge port of the cyclone separator is connected with the feed port of the cyclone separator through a vacuum feeding pipeline, and the discharge port of the cyclone separator is connected with the feed port of the packaging bin 13 through a pipeline, and the discharge port of the packaging bin 13 The port is connected with the shut-off fan through a pipeline, and the shut-off fan is connected with the feed port of the metal detector 14, and the discharge port of the metal detector 14 is connected with the automatic packaging machine 15 through a pipeline.

作为优选,所述料仓3和过滤器4均设置有两个,所述过滤器4为0.22微米无菌钛棒过滤器,所述粉碎机2为摆锤式粗粉碎机,所述粉碎机上设置有快开式观察维修孔16,所述粉碎机2与料仓3的进料口之间的管道上设置有气动蝶阀,所述料仓3的出料口处的管道上设置有气动球阀,所述料仓3与过滤器4之间的真空上料管道上设置有清洗排放口24,所述料仓3上设置有震击器17、视孔灯18和快开式观察维修孔16,所述料仓3的底部设置有带刹车片的轮子19。As preferably, the silo 3 and the filter 4 are provided with two, the filter 4 is a 0.22 micron sterile titanium rod filter, the pulverizer 2 is a pendulum type coarse pulverizer, and the pulverizer is equipped with two A quick-opening observation and maintenance hole 16 is provided, a pneumatic butterfly valve is provided on the pipeline between the pulverizer 2 and the feed port of the silo 3, and a pneumatic ball valve is provided on the pipeline at the discharge port of the hopper 3 , the vacuum feeding pipeline between the silo 3 and the filter 4 is provided with a cleaning discharge port 24, and the silo 3 is provided with a jar 17, a viewing hole lamp 18 and a quick-opening observation and maintenance hole 16 , the bottom of the bin 3 is provided with wheels 19 with brake pads.

作为优选,所述料仓3上端的真空口通过管道与真空系统连接,所述真空系统包括真空机组20,所述真空机组20通过管道分别与两组0.01微米的无菌过滤器21连接,所述无菌过滤器21通过管道分别与料仓3上端的真空口连接,所述无菌过滤器21的进气口和出气口处的管道上均设置有球阀,所述料仓3上端的真空口处的管道上设置有气动气阀,所述无菌过滤器21与料仓3之间的管道上设置有真空检测仪22和平衡阀23。As preferably, the vacuum port at the upper end of the silo 3 is connected to a vacuum system through a pipeline, and the vacuum system includes a vacuum unit 20, and the vacuum unit 20 is respectively connected to two groups of 0.01 micron sterile filters 21 through a pipeline, so that The sterile filter 21 is respectively connected to the vacuum port on the upper end of the silo 3 through pipelines, ball valves are arranged on the pipelines at the air inlet and the air outlet of the sterile filter 21, and the vacuum at the upper end of the silo 3 The pipeline at the mouth is provided with a pneumatic valve, and the pipeline between the sterile filter 21 and the silo 3 is provided with a vacuum detector 22 and a balance valve 23 .

作为优选,所述料仓3上端的气口通过管道与罗茨风机系统连接,所述罗茨风机系统包括罗茨风机组25,所述罗茨风机组25通过管道分别与两组0.01微米的无菌过滤器连接,所述无菌过滤器通过管道分别与料仓3上端的气口连接,所述无菌过滤器的进气口和出气口处的管道上均设置有球阀,所述料仓3上端的气口处的管道上设置有布风阀,所述无菌过滤器与料仓3之间的管道上设置有风量检测仪26和平衡阀。As preferably, the gas port at the upper end of the silo 3 is connected to the Roots blower system through a pipeline, and the Roots blower system includes a Roots blower unit 25, and the Roots blower unit 25 is respectively connected to two groups of 0.01 micron air-free blowers through pipelines. Bacteria filter is connected, and described aseptic filter is connected with the air port of feed bin 3 upper ends respectively through pipeline, and ball valve is all arranged on the pipeline at the air inlet of described sterile filter and gas outlet place, and described feed bin 3 An air distribution valve is provided on the pipeline at the air port at the upper end, and an air volume detector 26 and a balance valve are provided on the pipeline between the sterile filter and the silo 3 .

作为优选,所述过滤器4上端的真空口通过管道与真空机组20连接,真空口与真空机组之间的管道上设置有平衡阀和真空检测仪,所述过滤器4上端的真空口处设置有气动阀门;所述过滤器4上端的风口通过管道与仪表风气源分配装置31连接,所述仪表风气源分配装置31上分别设置有直径4-12mm的仪表风管道、气动阀风管道、平衡阀风管道、直径20-38的反吹风管道。As preferably, the vacuum port at the upper end of the filter 4 is connected to the vacuum unit 20 through a pipeline, a balance valve and a vacuum detector are arranged on the pipeline between the vacuum port and the vacuum unit, and a vacuum detector at the upper end of the filter 4 is provided There is a pneumatic valve; the tuyere at the upper end of the filter 4 is connected to the instrument air source distribution device 31 through a pipeline, and the instrument air source distribution device 31 is respectively provided with an instrument air pipe with a diameter of 4-12 mm, a pneumatic valve air pipe, and a balance Valve air duct, anti-air duct with a diameter of 20-38.

作为优选,所述晶体暂存罐6和混合罐9上均设置有视孔灯、罐盖、搅拌装置和保温夹套,所述罐盖上设置有观察孔,所述晶体暂存罐6和混合罐9的出料口处均设置有电动调节阀,电动调节阀通过软连接与低温螺旋粉碎机相连,低温螺旋粉碎机上分别在粉碎机定刀盘、动刀盘上设置有进风过滤器32,所述进风过滤器内安装0.45mm预过滤器和0.01mm无菌精过滤器。As preferably, the crystal temporary storage tank 6 and the mixing tank 9 are all provided with a sight light, a tank cover, a stirring device and a heat preservation jacket, and the tank cover is provided with an observation hole, and the crystal temporary storage tank 6 and The discharge port of the mixing tank 9 is equipped with an electric control valve, which is connected with the low-temperature screw pulverizer through a soft connection, and the low-temperature screw pulverizer is provided with an air inlet filter on the fixed cutter head and the movable cutter head of the grinder respectively. 32. A 0.45mm pre-filter and a 0.01mm sterile fine filter are installed in the air inlet filter.

作为优选,所述旋风分离器8上方通过管道与引风机33相连,所述引风机33通过管道与水幕除尘系统34相连;所述上料仓11内的进料管道进入料仓3-5cm,上料仓内的出料管距离底部3-5cm。As preferably, the top of the cyclone separator 8 is connected to the induced draft fan 33 through a pipeline, and the induced draft fan 33 is connected to the water curtain dust removal system 34 through a pipeline; , The discharge pipe in the upper silo is 3-5cm away from the bottom.

作为优选,所述右旋糖酐生物大分子成品自动收集粉碎包装系统还设置有清洗系统,所述清洗系统包括过热水系统29和纯水系统30,所述过热水系统29和纯水系统30的出水口通过管道分别与料仓3、晶体暂存罐6、混合罐9、过滤器4上的进水口连接,所述过热水系统29和纯水系统30的出水口处的管道上均设置有球阀,所述料仓3、晶体暂存罐6、混合罐9、过滤器4上的进水口处均设置有气动阀,所述料仓3、晶体暂存罐6、混合罐9、过滤器4内均设置有喷淋管27,喷淋管27上设置有喷淋头28,喷淋管27与进水口连接,所述料仓3和过滤器4内的喷头为扇形60度喷淋头,所述晶体暂存罐6和混合罐9内的喷头为360度旋转喷淋头,在晶体暂存罐6和混合罐9下方的电动调节阀前设排空阀12,低温螺旋粉碎机7和振动分筛机10与旋风分离器连接的管道上设排空阀。As preferably, said dextran biomacromolecule finished product automatically collects and pulverizes packaging system is also provided with cleaning system, and described cleaning system comprises superheated water system 29 and pure water system 30, the superheated water system 29 and pure water system 30 The water outlet is respectively connected with the water inlets on the silo 3, the crystal temporary storage tank 6, the mixing tank 9, and the filter 4 through pipelines, and the pipelines at the water outlets of the superheated water system 29 and the pure water system 30 are all provided with There is a ball valve, and the feed bin 3, the crystal temporary storage tank 6, the mixing tank 9, and the water inlet on the filter 4 are all provided with pneumatic valves, and the feed bin 3, the crystal temporary storage tank 6, the mixing tank 9, the filter Spray pipes 27 are arranged in the device 4, and a spray head 28 is arranged on the spray pipe 27, and the spray pipe 27 is connected with the water inlet. Head, the nozzle in the crystal temporary storage tank 6 and the mixing tank 9 is a 360-degree rotating shower head, and an emptying valve 12 is set before the electric control valve below the crystal temporary storage tank 6 and the mixing tank 9, and the low-temperature screw pulverizer 7 and the pipeline connected to the vibrating screen 10 and the cyclone separator are provided with an emptying valve.

作为优选,所述右旋糖酐生物大分子成品自动收集粉碎包装系统还包括控制系统,所述控制系统包括控制器数据通讯系统,所述气动阀、电动调节阀、平衡阀和真空检测仪、风量检测仪均与控制器数据通讯系统电联接,控制器数据通讯系统包括检测仪变送器和气动阀、电动调节阀、平衡阀执行器,所述控制器数据通讯系统与操作微机相连,所述控制系统可以实现现场控制,进一步可以实现电脑联机远程控制。As a preference, the automatic collection, pulverization and packaging system for finished dextran biomacromolecule products also includes a control system, the control system includes a controller data communication system, and the pneumatic valve, electric regulating valve, balance valve, vacuum detector, and air volume detector They are all electrically connected with the controller data communication system. The controller data communication system includes detector transmitters, pneumatic valves, electric regulating valves, and balance valve actuators. The controller data communication system is connected with the operating microcomputer. The control system On-site control can be realized, and computer online remote control can be further realized.

Claims (9)

1.右旋糖酐生物大分子成品自动收集粉碎包装系统,其特征在于,包括干燥机(1),所述干燥机(1)的出料口与粉碎机(2)的进料口连通,所述粉碎机(2)的出料口通过管道与料仓(3)的进料口连接,所述料仓(3)的出料口通过真空上料管道与过滤器(4)的进料口连接,所述过滤器(4)的出料口通过管道与关风机(5)连接,所述关风机(5)与晶体暂存罐(6)的进料口连接,所述晶体暂存罐(6)的出料口通过管道与低温螺旋粉碎机(7)的进料口连接,所述低温螺旋粉碎机(7)的出料口通过真空上料管道与旋风分离器(8)的进料口连接,所述旋风分离器(8)的出料口通过管道与关风机连接,所述关风机与混合罐(9)的进料口连接,所述混合罐(9)的出料口通过管道与振动分筛机(10)的进料口连接,所述振动分筛机(10)的出料口通过管道与上料仓(11)的进料口连接,所述上料仓(11)的出料口通过真空上料管道与旋风分离器的进料口连接,所述旋风分离器的出料口通过管道与包装料仓(13)的进料口连接,所述包装料仓(13)的出料口通过管道与关风机连接,所述关风机与金属探测仪(14)的进料口连接,所述金属探测仪(14)的出料口通过管道与自动包装机(15)连接。1. The finished product of dextran biomacromolecule automatically collects and pulverizes the packing system, is characterized in that, comprises drier (1), and the discharge port of described drier (1) is communicated with the feed inlet of pulverizer (2), and described pulverization The discharge port of machine (2) is connected with the feed port of feed bin (3) by pipeline, and the discharge port of described feed bin (3) is connected with the feed port of filter (4) by vacuum feeding pipeline, The discharge port of the filter (4) is connected with the shut-off fan (5) by pipeline, and the shut-off fan (5) is connected with the feed port of the crystal temporary storage tank (6), and the crystal temporary storage tank (6) ) is connected to the feed port of the low-temperature screw pulverizer (7) through a pipeline, and the discharge port of the low-temperature screw pulverizer (7) is connected to the feed port of the cyclone separator (8) through a vacuum feeding pipeline. Connect, the outlet of described cyclone separator (8) is connected with shut-off fan by pipeline, and described shut-off fan is connected with the feed inlet of mixing tank (9), and the discharge outlet of described mixing tank (9) passes pipeline Be connected with the feeding port of vibrating sieving machine (10), the discharge port of described vibrating sieving machine (10) is connected with the feeding port of upper feed bin (11) by pipeline, and described upper feed bin (11) The discharge port of the vacuum feeder is connected with the feed port of the cyclone separator through the vacuum feeding pipeline, and the discharge port of the cyclone separator is connected with the feed port of the packaging silo (13) through the pipeline, and the packaging silo (13) ) is connected with the blower blower by pipeline, and the blower blower is connected with the feed inlet of metal detector (14), and the discharge mouth of described metal detector (14) is connected with automatic packing machine (15) by pipeline connect. 2.根据权利要求1所述右旋糖酐生物大分子成品自动收集粉碎包装系统,其特征在于:所述料仓(3)和过滤器(4)均设置有两个,所述过滤器(4)为0.22微米无菌钛棒过滤器,所述粉碎机(2)为摆锤式粗粉碎机,所述粉碎机(2)上设置有快开式观察维修孔(16),所述粉碎机(2)与料仓(3)的进料口之间的管道上设置有气动蝶阀,所述料仓(3)的出料口处的管道上设置有气动球阀,所述料仓(3)与过滤器(4)之间的真空上料管道上设置有清洗排放口(24),所述料仓(3)上设置有震击器(17)、视孔灯(18)和快开式观察维修孔(16),所述料仓(3)的底部设置有带刹车片的轮子(19)。2. according to claim 1 described dextran biomacromolecule finished product automatic collection crushing packaging system, it is characterized in that: described feed bin (3) and filter (4) are all provided with two, and described filter (4) is 0.22 micron sterile titanium rod filter, the pulverizer (2) is a pendulum type coarse pulverizer, and the pulverizer (2) is provided with a quick opening type observation and maintenance hole (16), and the pulverizer (2) ) and the feed port of the silo (3) are provided with a pneumatic butterfly valve, and the pipeline at the discharge port of the silo (3) is provided with a pneumatic ball valve, and the silo (3) and the filter A cleaning discharge port (24) is provided on the vacuum feeding pipeline between the devices (4), and a jar (17), a viewing hole lamp (18) and a quick-opening observation and maintenance device are provided on the silo (3). holes (16), the bottom of the feed bin (3) is provided with wheels (19) with brake pads. 3.根据权利要求2所述右旋糖酐生物大分子成品自动收集粉碎包装系统,其特征在于:所述料仓(3)上端的真空口通过管道与真空系统连接,所述真空系统包括真空机组(20),所述真空机组(20)通过管道分别与两组0.01微米的无菌过滤器(21)连接,所述无菌过滤器(21)通过管道分别与料仓(3)上端的真空口连接,所述无菌过滤器(21)的进气口和出气口处的管道上均设置有球阀,所述料仓(3)上端的真空口处的管道上设置有气动气阀,所述无菌过滤器(21)与料仓(3)之间的管道上设置有真空检测仪(22)和平衡阀(23)。3. according to claim 2 described dextran biomacromolecule finished product automatic collection pulverization packing system, it is characterized in that: the vacuum mouth of described silo (3) upper end is connected with vacuum system by pipeline, and described vacuum system comprises vacuum unit (20 ), the vacuum unit (20) is respectively connected with two groups of 0.01 micron sterile filters (21) through pipelines, and the sterile filters (21) are connected with the vacuum port on the upper end of the feed bin (3) through pipelines , the pipeline at the air inlet and the air outlet of the sterile filter (21) is provided with a ball valve, and the pipeline at the vacuum port at the upper end of the silo (3) is provided with a pneumatic valve, and the airless A vacuum detector (22) and a balance valve (23) are arranged on the pipeline between the bacteria filter (21) and the feed bin (3). 4.根据权利要求3所述右旋糖酐生物大分子成品自动收集粉碎包装系统,其特征在于:所述料仓(3)上端的气口通过管道与罗茨风机系统连接,所述罗茨风机系统包括罗茨风机组(25),所述罗茨风机组(25)通过管道分别与两组0.01微米的无菌过滤器连接,所述无菌过滤器通过管道分别与料仓(3)上端的气口连接,所述无菌过滤器的进气口和出气口处的管道上均设置有球阀,所述料仓(3)上端的气口处的管道上设置有布风阀,所述无菌过滤器与料仓(3)之间的管道上设置有风量检测仪(26)和平衡阀。4. according to claim 3 described dextran biomacromolecule finished products automatic collection pulverization packaging system, it is characterized in that: the air port at the upper end of the silo (3) is connected with the Roots blower system through a pipeline, and the Roots blower system includes a blower blower system. Roots blower unit (25), said Roots blower unit (25) is respectively connected with two groups of 0.01 micron sterile filters through pipelines, and said sterile filters are respectively connected with the air port on the upper end of the feed bin (3) through pipelines , the pipeline at the air inlet and the air outlet of the sterile filter is provided with a ball valve, and the pipeline at the gas outlet at the upper end of the silo (3) is provided with an air distribution valve, and the sterile filter and An air volume detector (26) and a balance valve are arranged on the pipeline between the silos (3). 5.根据权利要求4所述右旋糖酐生物大分子成品自动收集粉碎包装系统,其特征在于:所述过滤器(4)上端的真空口通过管道与真空机组(20)连接,真空口与真空机组之间的管道上设置有平衡阀和真空检测仪,所述过滤器(4)上端的真空口处设置有气动阀门;所述过滤器(4)上端的风口通过管道与仪表风气源分配装置(31)连接,所述仪表风气源分配装置(31)上分别设置有直径4-12mm的仪表风管道、气动阀风管道、平衡阀风管道、直径20-38的反吹风管道。5. according to claim 4 described dextran biomacromolecule finished product automatic collection pulverization packing system, it is characterized in that: the vacuum mouth of described filter (4) upper end is connected with vacuum unit (20) by pipeline, the vacuum mouth and vacuum unit A balance valve and a vacuum detector are arranged on the pipeline between them, and a pneumatic valve is arranged at the vacuum port at the upper end of the filter (4); ) connection, the instrument air source distribution device (31) is respectively provided with an instrument air duct with a diameter of 4-12mm, a pneumatic valve air duct, a balance valve air duct, and a reverse blowing duct with a diameter of 20-38mm. 6.根据权利要求5所述右旋糖酐生物大分子成品自动收集粉碎包装系统,其特征在于:所述晶体暂存罐(6)和混合罐(9)上均设置有视孔灯、罐盖、搅拌装置和保温夹套,所述罐盖上设置有观察孔,所述晶体暂存罐(6)和混合罐(9)的出料口处均设置有电动调节阀,电动调节阀通过软连接与低温螺旋粉碎机相连,低温螺旋粉碎机上分别在粉碎机定刀盘、动刀盘上设置有进风过滤器(32),所述进风过滤器内安装0.45mm预过滤器和0.01mm无菌精过滤器。6. according to claim 5, said dextran biomacromolecule finished product automatically collects and pulverizes packaging system, it is characterized in that: said crystal temporary storage tank (6) and mixing tank (9) are all provided with eye-hole lamp, tank cover, stirring device and insulation jacket, the tank cover is provided with an observation hole, and the outlets of the crystal temporary storage tank (6) and the mixing tank (9) are all provided with electric regulating valves, and the electric regulating valves are connected to the The low-temperature spiral pulverizer is connected, and the low-temperature spiral pulverizer is provided with an air inlet filter (32) on the fixed cutter disc and the movable cutter disc of the pulverizer respectively, and a 0.45mm pre-filter and a 0.01mm sterile filter are installed in the air inlet filter. fine filter. 7.根据权利要求6所述右旋糖酐生物大分子成品自动收集粉碎包装系统,其特征在于:所述旋风分离器(8)上方通过管道与引风机(33)相连,所述引风机(33)通过管道与水幕除尘系统(34)相连;所述上料仓(11)内的进料管道进入料仓3-5cm,上料仓内的出料管距离底部3-5cm。7. according to claim 6 described dextran biomacromolecule finished product automatic collection pulverization packing system, it is characterized in that: above described cyclone separator (8) is connected with induced draft fan (33) by pipeline, and described induced draft fan (33) passes through The pipeline is connected to the water curtain dedusting system (34); the feeding pipeline in the upper feeding bin (11) enters the feeding bin by 3-5cm, and the discharge pipe in the upper feeding bin is 3-5cm away from the bottom. 8.根据权利要求7所述右旋糖酐生物大分子成品自动收集粉碎包装系统,其特征在于:8. according to claim 7 described dextran biomacromolecule finished product automatically collects crushing packaging system, it is characterized in that: 还设置有清洗系统,所述清洗系统包括过热水系统(29)和纯水系统(30),所述过热水系统(29)和纯水系统(30)的出水口通过管道分别与料仓(3)、晶体暂存罐(6)、混合罐(9)、过滤器(4)上的进水口连接,所述过热水系统(29)和纯水系统(30)的出水口处的管道上均设置有球阀,所述料仓(3)、晶体暂存罐(6)、混合罐(9)、过滤器(4)上的进水口处均设置有气动阀,所述料仓(3)、晶体暂存罐(6)、混合罐(9)、过滤器(4)内均设置有喷淋管(27),喷淋管(27)上设置有喷淋头(28),喷淋管(27)与进水口连接,所述料仓(3)和过滤器(4)内的喷头为扇形60度喷淋头,所述晶体暂存罐(6)和混合罐(9)内的喷头为360度旋转喷淋头,在晶体暂存罐(6)和混合罐(9)下方的电动调节阀前设排空阀(12),低温螺旋粉碎机(7)和振动分筛机(10)与旋风分离器连接的管道上设排空阀。A cleaning system is also provided, and the cleaning system includes a superheated water system (29) and a pure water system (30). warehouse (3), crystal temporary storage tank (6), mixing tank (9), the water inlet connection on the filter (4), the water outlet of the superheated water system (29) and the pure water system (30) Ball valves are all arranged on the pipelines, and pneumatic valves are all arranged at the water inlets of the feed bin (3), the crystal temporary storage tank (6), the mixing tank (9), and the filter (4). (3), crystal temporary storage tank (6), mixing tank (9), filter (4) are all provided with spray pipe (27), and spray pipe (27) is provided with shower head (28), Spray pipe (27) is connected with water inlet, and the spray head in described silo (3) and filter (4) is fan-shaped 60 degree spray head, and described crystal temporary storage tank (6) and mixing tank (9) The spray head inside is a 360-degree rotating spray head, and an emptying valve (12), a low-temperature screw pulverizer (7) and a vibrating sieve are installed in front of the electric regulating valve below the crystal temporary storage tank (6) and the mixing tank (9). An emptying valve is established on the pipeline that the machine (10) is connected with the cyclone separator. 9.根据权利要求8所述右旋糖酐生物大分子成品自动收集粉碎包装系统,其特征在于:还包括控制系统,所述控制系统包括控制器数据通讯系统,所述气动阀、电动调节阀、平衡阀和真空检测仪、风量检测仪均与控制器数据通讯系统电联接,控制器数据通讯系统包括检测仪变送器和气动阀、电动调节阀、平衡阀执行器,所述控制器数据通讯系统与操作微机相连,所述控制系统可以实现现场控制,进一步可以实现电脑联机远程控制。9. According to claim 8, said dextran biomacromolecule finished product automatically collects, pulverizes and packs the system, it is characterized in that: it also includes a control system, said control system includes a controller data communication system, said pneumatic valve, electric regulating valve, balance valve The vacuum detector and air flow detector are electrically connected with the controller data communication system. The controller data communication system includes detector transmitters, pneumatic valves, electric regulating valves, and balance valve actuators. The controller data communication system is connected with The operating microcomputer is connected, and the control system can realize on-site control, and can further realize computer online remote control.
CN201721805318.2U 2017-12-21 2017-12-21 Dextran large biological molecule finished product collects crushing packing system automatically Expired - Fee Related CN207725724U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108001744A (en) * 2017-12-21 2018-05-08 山东金朗生物科技有限公司 Dextran large biological molecule finished product collects crushing packing system and method automatically

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108001744A (en) * 2017-12-21 2018-05-08 山东金朗生物科技有限公司 Dextran large biological molecule finished product collects crushing packing system and method automatically
CN108001744B (en) * 2017-12-21 2024-04-30 山东金洋药业有限公司 Automatic collecting, crushing and packaging system and method for dextran biomacromolecule finished products

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