CN206587064U - A kind of pharmacological evaluation rat oral gavage fixed station - Google Patents

Abstract

A rat gavage fixation platform for pharmacological experiments, the telescopic support rod is fixed on the base through locking screws, the fixed plate is set on the top of the telescopic support rod, and the fixed plate is threadedly connected with the telescopic support rod; the syringe bracket is connected to the right side of the fixed plate , the syringe is placed on the syringe bracket; the bracket is set in the middle of the fixing plate, the bracket and the fixing plate are threadedly connected to support the fixing piece, the adjusting nut is set on the top of the bracket, the fixing piece is movably connected with the bracket through the adjusting nut, and the fixing piece is made of transparent material The overall shape is ellipsoidal; the inlet cover is installed on the left end of the fixing piece, and the through holes are distributed around the fixing piece, and its position is convenient for subcutaneous and intraperitoneal injection of rats; On the top and bottom of the fixing part, the design of the compression fixing hole can be used to reinsert the clip; the gavage port is located at the right end of the fixing part, which is convenient for the worker to insert the syringe from the gavage port into the rat's stomach.

Description

A rat gavage fixation platform for pharmacological experiments

technical field

The utility model relates to the field of traditional Chinese pharmacy, in particular to a rat gavage fixed platform for pharmacological experiments.

Background technique

In recent years, with the development of science and technology and the integration of multiple sciences, animal experiments have become the basic method of medicine, food safety science and other related scientific research. During the test, according to the purpose of the test, the type of test animal, and the dosage form and dose of the drug or food, it is necessary to implement different drug administration methods to the test animals, and rats are one of the commonly used test animals.

Rats are a variant of the wild Rattus norvegicus. They were raised artificially in the late 18th century. They are nocturnal, prefer to live alone, are timid and fearful, like to bite, have strong disease resistance, strong sensitivity, and relatively consistent genetics. , which responds relatively similarly to experimental conditions, is known as a precise biological research tool, and is widely used in the research of endocrinology, medicine, behavior, geriatrics, tumors, infectious diseases, cardiovascular diseases, and traditional Chinese medicine. There are many varieties and strains, which can be used for different experiments. Rat is an animal model commonly used to simulate the human body in medical experiments. Through the study of its mechanism and laws in physiology, pharmacology, pathology, toxicology and psychology, etc., to obtain relevant data and information useful to the human body, And then provide guidance for medical research and development.

Rats are one of the most commonly used experimental animals. Many experiments require administration of drugs and blood collection to them. A suitable fixation method is the guarantee for the smooth progress of the experiments. There are many ways to administer drugs and collect blood in rats, but most of them are complicated to operate, such as requiring anesthesia or surgery, etc., which not only cause great damage to rats, easily lead to death of rats, but also affect experimental data. However, at present, students in most universities and scientific research institutes and even specialized scientific research personnel are often scratched or bitten by rats due to poor grasping of rats when performing gastric administration to rats, resulting in the midway of gastric administration. Forced to interrupt or terminate, thus prolonging the test time and reducing the test efficiency. Its main problem is that in the prior art, close contact or direct contact with rats is required to complete the whole process of gavage. In order to improve the safety of the operation and the work efficiency of gavage, it is necessary to seek a Using a tool or equipment to replace this dangerous link can solve a lot of problems in actual work.

This shows that in order to reduce unnecessary troubles, improve safety in the test process, and make the test go smoothly, it is very necessary to propose a rat gavage fixed platform for pharmacological experiments.

Contents of the invention

The utility model provides a rat gavage fixed platform for pharmacological experiments, which can improve the safety in the test process and make the test go smoothly.

The technical solution adopted by the utility model to solve the above-mentioned technical problems is: a rat gavage fixed platform for pharmacological experiments, including a base, a telescopic support rod, a locking screw, a fixing plate, a syringe bracket, a syringe, a bracket, an adjusting nut, Fixtures, access caps, through holes, compression fixing holes and gavage ports,

The base is placed on the test bench, the telescopic support rod is fixed on the base through a locking screw, the fixed plate is arranged on the top of the telescopic support rod, and the fixed plate is threadedly connected with the telescopic support rod; the syringe bracket is connected to the On the right side of the fixed plate, the syringe is placed on the syringe holder;

The bracket is arranged in the middle of the fixing plate, the bracket and the fixing plate are threadedly connected to support the fixing piece, the adjusting nut is arranged on the top of the bracket, the fixing piece is movably connected with the bracket through the adjusting nut, and the fixing piece is made of a transparent material. The whole is ellipsoidal;

The inlet cover is installed on the left end of the fixing part, and through holes are distributed around the fixing part. The top and bottom of the piece, the design of the compression fixing hole can be used to insert the clip again, further compressing the mouse space, so as to further fix the mouse; the gavage port is located at the right end of the fixation piece, which is convenient for the worker to insert the syringe into the rat from the gavage port stomach.

Beneficial effects of the utility model:

1. The fixing part of the utility model is an ellipsoidal transparent material, which is convenient for workers to observe; it also adopts a variable-diameter design, which can well adapt to the bodies of rats of different shapes, can well fix the rats, and There is no trauma to the rat; with the clamp, the rat is flexibly fixed and is in a relatively relaxed state.

2. The fixing part of the utility model can be rotated in 360 degrees, which is convenient for workers to adjust the fixing part to the best position for feeding the rats.

3. The fixing part of the utility model is also provided with a plurality of through holes, which can be used for subcutaneous and intraperitoneal injection of rats and enhanced air permeability.

4. The utility model has the advantages of simple structure, convenient and fast use, low cost and easy manufacture.

Description of drawings

Fig. 1 is an overall isometric side view of the utility model.

Fig. 2 is the front view of the utility model.

Fig. 3 is an isometric side view of the fixing part of the present invention.

Fig. 4 is a front view of the fixing part of the present invention.

detailed description

Below in conjunction with Fig. 1, Fig. 2, Fig. 3, and Fig. 4, the utility model is described in further detail.

A rat gastric gavage fixation platform for pharmacological experiments, including a base 1, a telescopic support rod 2, a locking screw 3, a fixing plate 4, a syringe bracket 5, a syringe 6, a bracket 7, an adjustment nut 8, a fixing piece 9, and an inlet cover 10. Through hole 11, compression fixing hole 12 and gavage opening 13,

The base 1 is placed on the test bench, the telescopic support rod 2 is fixed on the base 1 by the locking screw 3, the fixed plate 4 is arranged on the top of the telescopic support rod 2, and the fixed plate 4 is threadedly connected with the telescopic support rod 2 ; The syringe bracket 5 is connected to the right side of the fixed plate 4, and the syringe 6 is placed on the syringe bracket 5;

Described support 7 is located at the middle part of fixed plate 4, and support 7 is threadedly connected with fixed plate 4 and is used to support fixed part 9, and adjusting nut 8 is located at the top of support 7, and fixed part 9 is flexibly connected with support 7 by adjusting nut 8, so The above-mentioned fixing part 9 is made of a transparent material, and is in the shape of an ellipsoid as a whole;

Described inlet cover 10 is installed on the left end of fixture 9, and through hole 11 is distributed around fixture, and its position is convenient to carry out subcutaneous and intraperitoneal injection to rat, and through hole 11 can also enhance gas permeability; Described compression fixation hole 12 are located at the top and bottom of the fixing part 9 respectively, and the design of the compression fixing hole 12 can be used to reinsert the clip to further compress the mouse space, thereby further fixing the mouse; The person inserts the syringe 6 into the stomach of the rat from the gavage port 13.

Working principle: first rotate the fixing part 9 to the horizontal, insert the clip from the compression fixing hole 12, then put the rat into the fixing part 9 from the entrance cover 10, and the mouth of the rat is just at the gavage opening 12; The fixing part 9 adjusts the gavage port 12 to a suitable position for gavage, and inserts the syringe 6 through the gavage port 12 into the rat's stomach for drug administration; finally, the fixing part 9 is rotated to the horizontal direction, and the clip is pulled out to expand the rat fixing part The space within 9 is convenient for observing the reaction of rats after drug administration.

The above content has described the specific embodiment of the present utility model with reference to Fig. 1, Fig. 2, Fig. 3, and Fig. 4, and those skilled in the art should understand that the product of the present utility model is not only limited to the embodiment described above, and Various modifications can be made without departing from the spirit of the present invention, and said modifications should also be included within the scope of the present invention. The scope of the present invention should be defined by the appended claims and their equivalents.

Claims (1)

1. a kind of pharmacological evaluation rat oral gavage fixed station, including base（1）, telescopic supporting rod（2）, set and locking screw（3）, it is fixed Plate（4）, syringe rack（5）, syringe（6）, support（7）, adjusting nut（8）, fixture（9）, inlet cover（10）, through hole （11）, compression fixing hole（12）With gavage mouthful（13）, it is characterised in that：

Described base（1）It is placed on experimental bench, telescopic supporting rod（2）Pass through set and locking screw（3）It is fixed on base（1）On, institute The fixed plate stated（4）Located at telescopic supporting rod（2）Top, fixed plate（4）With telescopic supporting rod（2）Screw thread is connected；Described note Emitter support（5）It is connected to fixed plate（4）Right side, syringe（6）It is placed in syringe rack（5）On；

Described support（7）Located at fixed plate（4）Middle part, support（7）With fixed plate（4）It is threadedly coupled for supporting fixture （9）, adjusting nut（8）Located at support（7）Top, fixture（9）Pass through adjusting nut（8）With support（7）It is flexibly connected, it is described Fixture（9）It is made using transparent material, overall is in spheroid shape；

Described inlet cover（10）It is installed on fixture（9）Left end, through hole（11）It is distributed in fixture surrounding；Described compression Fixing hole（12）It is respectively arranged on fixture（9）Top and bottom, gavage mouthful（13）Located at fixture（9）Right-hand member.