CN204521035U - Large operations area is regained consciousness experimental rat fixture - Google Patents

Abstract

The utility model relates to the technical field of experimental equipment, in particular to a fixture for awake experimental rats with a large operating area, comprising an arc-shaped supporting plate and a fixing belt. The slot is connected with a fixed belt on the arc-shaped supporting plate, and the fixed belt surrounds the arc-shaped supporting plate for at least one circle in the radial direction; the bottom of the arc-shaped supporting plate is equipped with a base. The beneficial effect of the utility model is that it is open, can be operated in a large area, and has good operational stability; the shape is a semicircular groove structure, which can make the shape of the experimental animal conform to the device while ensuring the reliability of the fixed experimental animal, and reduce the animal's fatigue as much as possible. Stress state; the method of two-point fixation on the shoulder and hip of the animal is convenient for setting electrodes, catheters, and sample collection; it can effectively fix animals in chronic, long-term or awake experiments; it is easy to operate and has good stability. The size can be adjusted according to the size of the useful experimental animal.

Description

Fixation device for awake experimental rats with large operating area

technical field

The utility model relates to the technical field of experimental equipment, in particular to a fixation device for awake experimental rats with a large operating area.

Background technique

As one of the most commonly used experimental animals in scientific research such as medicine, biology and psychology, experimental rats often require Fixation, accompanied by the setting of electrodes, catheters and other devices, in order to record data, administer drugs and collect samples. Therefore, it has always been the research direction of researchers to effectively and reasonably immobilize experimental animals while reducing the stress state of experimental animals as much as possible.

At present, the commonly used experimental rat fixation devices are roughly divided into barrel type, box type and plate type. The former two are to put rats into a conical or square semi-closed restraint, the operating surface is narrow, and the head is not fixed. As the chronic experimental rats gradually wake up, their head and trunk will be in place. Twisting in the cage is not conducive to the setting of electrodes and catheters and the experimental operation, and the experimental rats in the restrained state will have a strong stress response, which seriously hinders the operation of the experimenter and affects the accuracy of the experimental data. The plate-type fixation device binds the limbs of experimental rats to a rectangular plate. This binding method often easily causes ischemic necrosis of the limbs. Although these fixation methods can effectively fix the experimental rats, they are not conducive to the experimental operation, and the damage to the experimental rats is likely to cause the instability of the experimental basic value.

The Chinese utility model patent with the application number "201420238368.7", the authorized announcement number "CN 203841837 U" and the title "A New Type of Rat Fixation Device" discloses a new type of rat fixation device, including a fixation table, a head fixation device, limb immobilizer, rubber band, defecation hole, groove and tether hook, the head immobilizer is located at the front end of the fixed platform; the limb immobilizer is distributed around the fixed platform, and the limb immobilizer is provided with a groove , the position of the groove is suitable for the limbs of the rat; one end of the rubber band is bound to the tether hook on the fixed platform on one side of the limb fixer, and the other end of the rubber band is used to fix the head of the rat or limbs. When in use, grab the rat and put it on the rat fixing device, and fix the rat through the head holder and the limb holder, so as to conduct the test; fix the head holder and the limb holder on the fixing platform, so that the fixing device It will not turn with the rats; use rubber bands to fix the head and limbs, and the stretchability of the rubber bands can better adapt to rats of different sizes, and it is also easy to disassemble. The defecation hole at the back of the fixed table is convenient for rats to defecate . The defect of this utility model patent is: 1, can't adjust size; 2. The fixation effect with rubber band is not ideal; the rubber band of the device is elastic material, once the experimental animal struggles or bites, it is not conducive to the fixation effect; 3. The device is a better choice for fixing the experimental animal in anesthetized state. However, the reliability of immobilization in conscious or chronic experimental animals is greatly limited.

The Chinese utility model patent with the application number "201320424330.4", the authorized announcement number "CN 203400220 U" and the title "A Rat Upper Limb Restraint Device" discloses a rat upper limb restraint device, which includes a T-shaped plate and at least two A restraint belt, wherein first holes are provided on both sides of the vertical plate of the T-shaped plate; second holes are respectively provided on both sides of the horizontal plate part on both sides of the intersection of the horizontal plate and the vertical plate of the T-shaped plate. When in use, place the T-shaped restraint device on the chest of the rat, pass the restraint belt through the first hole, fix the vertical board on the rat's chest, and fix the horizontal board on the upper limb of the rat after the restraint belt passes through the second hole, The rat is thus restrained. The defects of this utility model patent are: 1. The shape of the T-shaped plate does not match well with the body shape of rats; 2. Restraining animal limbs can easily cause ischemic necrosis; 3. Lack of restraint of hind limbs will greatly interfere with experimental operations.

Therefore, designing a fixation device that is easy to use, has a large experimental operation area, and causes little damage to animals will provide better research tools for research in the fields of medicine, biology, and psychology.

Utility model content

The purpose of the utility model is to overcome the deficiencies of the prior art, and provide an open, large operating area and stable operation for awake experimental rats.

In order to achieve the above object, the utility model provides a large operating area sober experimental rat fixation device, including an arc-shaped supporting plate and a fixing belt, and the two sides of the arc-shaped supporting plate in the width direction are respectively provided with two The groove is connected with a fixing belt on the arc-shaped supporting plate, and the fixing belt surrounds the arc-shaped supporting plate at least one circle along the radial direction.

A base is configured on the bottom of the arc-shaped supporting plate.

Preferably, the arc-shaped plate is a semi-circular groove-like structure. When experimental rats or other animals are placed on the arc-shaped supporting board, their head and neck can perform limited activities, which effectively ensures the use and operation of electrodes and catheters placed on their skulls, oral cavity, eyes and ears.

Preferably, the fixing belt is made of flexible materials.

Preferably, the arc-shaped pallet includes a first pallet and a second pallet, and a sliding connection structure is formed between the first pallet and the second pallet along their respective length directions.

The two grooves on both sides of the arc-shaped supporting plate are specifically: the first supporting plate is symmetrically provided with a first groove and a second groove on both sides in its width direction, and the second supporting plate is provided with a first groove and a second groove on both sides in its width direction. A third groove and a fourth groove are arranged laterally symmetrically.

Preferably, the first pallet and the second pallet can move in parallel. As long as the two ends of the first supporting board and the second supporting board are pulled respectively, the distance between the first supporting board and the second supporting board can be adjusted (that is, the overall length of the arc-shaped supporting board) to adapt to different body shapes of rats .

Preferably, the first groove and the second groove are respectively arranged at the middle sections of the two sides in the length direction of the first pallet, and when the animal lies prone or supine on the fixing device, its left and right forelimbs They are respectively placed in the first groove and the second groove to form a suspended state, so that the animal's left and right forelimbs have no focus when they are moving, and avoid struggling to escape. Electrodes can be placed on the exposed forelimbs on the premise of ensuring the reliability of the fixation and catheters.

Preferably, the third groove and the fourth groove are respectively arranged at the middle sections of the two sides in the length direction of the second pallet. When the animal lies prone or supine in the fixing device, its left and right hind limbs respectively Placed in the third groove and the fourth groove to form a suspended state, so that the left and right hind limbs of the animal have no focus when moving, so as to avoid struggling to escape. Electrodes and catheter.

Preferably, the first groove, the second groove, the third groove and the fourth groove are all smooth semicircular structures, and the size of the groove conforms to the size of the animal's limbs. The first groove and the second groove The distance between the grooves, the distance between the third groove and the fourth groove is respectively the same width as the chest and hips of the experimental animal, which ensures that the experimental animal fits comfortably when placed in the fixing device, and at the same time facilitates The use and operation of placing electrodes and catheters on the chest, spine and kidneys of experimental animals.

Preferably, the first pallet is provided with a slide groove along its length direction, and the bottom surface of the second pallet is fixedly connected to the limit rod.

The limiting rod passes through the chute so that the first supporting plate and the second supporting plate form a sliding connection, and the limiting rod cooperates with the nut arranged at the bottom of the first supporting plate for positioning.

Preferably, a connecting plate protrudes from one side of the first supporting plate in the length direction, and the chute is opened on the connecting plate.

Preferably, the first pallet is provided with a first sawtooth-shaped hollow groove and a second sawtooth-shaped hollow groove on both sides of the first pallet in the length direction.

A first insert and a second insert are respectively provided on the two side edges of the second pallet in the length direction.

The first insert and the second insert correspond to pass through the first sawtooth-shaped hollow groove and the second sawtooth-shaped hollow groove respectively so that the first supporting board and the second supporting board form a sliding connection.

Preferably, the sliding connection structures formed by the first zigzag hollow groove and the first inserter, and the second zigzag hollow groove and the second insert respectively ensure the accuracy of the parallel sliding position of the first pallet and the second pallet .

Preferably, the first support plate is provided with a first fixing belt hole, and the second support plate is provided with a second fixing belt hole.

One end of the fixing strap is fixedly connected to the first fixing strap hole, and the other end of the fixing strap is fixedly connected to the second fixing strap hole.

Preferably, the fixing belt is a flat and wide structure.

Preferably, the fixing belt may be a Velcro, and the flexible surface of the Velcro is used as a strap, which is closely attached to the experimental animal, and is bonded and fixed from the shoulder and hip joint of the animal to the lower part of the main body of the fixing groove.

Preferably, one end of the upper surface of the arc-shaped pallet is provided with a straight bar along its width direction.

The straight rod can be made of metal, wood, stainless steel, or rubber, etc., and can be used for animals to bite in experiments, which conforms to the biting habits of animals.

Preferably, the base includes a support column and a bottom plate connected to the bottom surface of the support column, and the top surface of the support column is connected to the bottom surface of the arc-shaped supporting plate.

Preferably, the height of the support column is 6-10 cm, preferably 8 cm.

Preferably, the bottom plate is a cuboid hollow structure.

Preferably, the fastening device for awake experimental rats with a large operating area is made of high-temperature-resistant materials, which may be plastic materials, which are easy to form and assemble at one time in technology, or stainless steel materials. The high-temperature-resistant materials used ensure the reliability, simplicity and sanitation of the operation, and are easy to clean and disinfect.

The beneficial effects of the utility model are: 1. It is open, can be operated in a large area and has good operation stability; 2. The shape is a semicircular groove structure, which can make its body shape conform to the device while ensuring the reliability of fixing the experimental animals. Minimize the stress state of the animal; 2. Adopt the method of two-point fixation on the shoulder and hip of the animal, so that the device is open and has a large operating area, which is convenient for setting electrodes, catheters and sample collection; 3. It can be used for chronic 1. Animals in long-term or awake state experiments can be effectively fixed; 4. The operation is simple and stable, and the size can be adjusted according to the size of useful experimental animals; 5. The material of the fixing device can be high-temperature-resistant plastic, which is easy to clean and disinfect; The process is easy to form at one time, reduces the cost, and is convenient for assembly.

Description of drawings

Fig. 1 is the structural representation of the utility model.

Fig. 2 is a schematic structural view of the first pallet in the present invention.

Fig. 3 is a schematic structural view of the second pallet in the present invention.

in:

1-fixing belt 2-the first pallet 21-the first groove

22-the second groove 23-the chute 24-the nut

25-The first zigzag hollow slot 26-The second zigzag hollow slot 27-The first fixed belt hole

28-Straight rod 3-Second pallet 31-Third groove

32-the fourth groove 33-limit rod 35-the first plug-in

36-Second plug-in 37-Second fixing hole 4-Support column

5- Bottom plate

Detailed ways

Below in conjunction with accompanying drawing and specific embodiment, the utility model is described further.

Example 1:

As shown in FIGS. 1 to 3 , a fixation device for awake experimental rats with a large operating area includes a curved support plate and a fixation belt 1 .

The arc-shaped plate is a semi-circular groove-like structure. When experimental rats or other animals are placed on the arc-shaped supporting plate, their head and neck can carry out limited activities, effectively ensuring that their skulls, oral cavity, The operation of placing electrodes and catheters in the eyes and ears.

The arc-shaped supporting plate is provided with two grooves on both sides of its width direction, and the fixed belt 1 is connected to the arc-shaped supporting plate, and the fixed belt 1 surrounds the arc-shaped supporting plate for at least one circle in the radial direction. .

The fixing belt is made of flexible material.

A base is configured on the bottom of the arc-shaped supporting plate.

Example 2:

A fastening device for awake experimental rats with a large operating area as shown in Figures 1 to 3 includes an arc-shaped supporting plate and a fixing belt 1, and the fixing belt 1 surrounds the arc-shaped supporting plate for at least one week along the radial direction thereof.

The arc-shaped plate is a semi-circular groove structure, and the arc-shaped supporting plate includes a first supporting plate 2 and a second supporting plate 3, and a sliding connection is formed between the first supporting plate 2 and the second supporting plate 3 along their respective length directions Structures can be moved in parallel. As long as the two ends of the first supporting plate 2 and the second supporting plate 3 are respectively pulled, the distance between the first supporting plate 2 and the second supporting plate 3 can be adjusted (that is, the overall length of the arc-shaped supporting plate) to adapt to large Rats of different sizes.

The first pallet 2 is symmetrically provided with a first groove 21 and a second groove 22 on both sides in its width direction, and the second pallet 3 is symmetrically provided with a third groove 31 and a second groove 22 on both sides in its width direction. The fourth groove 32 .

When experimental rats or other animals are placed on the arc-shaped supporting board, their head and neck can perform limited activities, which effectively ensures the use and operation of electrodes and catheters placed on their skulls, oral cavity, eyes and ears.

The fixing belt is made of flexible material.

The first groove 21 and the second groove 22 are respectively arranged at the middle section positions on both sides of the length direction of the first supporting plate 2. When the animal lies prone or supine on the fixing device, its left and right forelimbs They are respectively placed in the first groove 21 and the second groove 22 to form a suspended state, so that the animal's left and right forelimbs have no focus when performing activities, avoiding struggle and escape, and can be exposed on the forelimbs on the premise of ensuring the reliability of fixation. Place electrodes and catheters.

The third groove 31 and the fourth groove 32 are respectively arranged at the middle section positions on both sides of the length direction of the second supporting plate 3. When the animal lies prone or supine in the fixing device, its left and right hind legs are placed The third groove 31 and the fourth groove 32 respectively form a suspended state, so that the animal's left and right hind limbs have no focus when they are moving, so as to avoid struggling to escape, and the exposed hind limbs can be placed on the premise of ensuring fixation and reliability. electrodes and catheters.

The first groove 21, the second groove 22, the third groove 31 and the fourth groove 32 are all smooth semicircular structures, and the size of the groove conforms to the size of the limbs of the animal. The first groove 21 and the fourth groove 32 The distance between the second groove 22, the distance between the third groove 31 and the fourth groove 32 are respectively the same width as the chest and hips of the experimental animal, which ensures that the experimental animal is placed in the fixture. The fit is comfortable, and at the same time, it is convenient to place electrodes and catheters on the chest, spine, kidneys and other parts of experimental animals.

Described first supporting plate 2 is provided with chute 23 on its lengthwise direction, and the bottom surface of the second supporting plate 3 is fixedly connected stop bar 33.

The limiting rod 33 passes through the chute 23 to form a sliding connection between the first pallet 2 and the second pallet 3 , and the limiting rod 33 cooperates with the nut 24 on the bottom of the first pallet 2 for positioning.

A connecting plate protrudes from one side of the first supporting plate 2 in the length direction, and the sliding groove 21 is opened on the connecting plate.

The first pallet 2 is provided with a first zigzag hollow groove 25 and a second zigzag hollow groove 26 on both side edges in the length direction.

A first insert 35 and a second insert 36 are respectively provided on the two side edges of the second pallet 3 in the length direction.

The first insert 35 and the second insert 36 pass through the first zigzag hollow groove 25 and the second zigzag hollow groove 26 respectively so that the first pallet 2 and the second pallet 3 form a sliding connection.

The sliding connection structures formed by the first zigzag hollow groove 25 and the first insert 35, the second zigzag hollow groove 26 and the second insert 36 respectively ensure the accuracy of the parallel sliding position of the first pallet and the second pallet. sex.

The first supporting board 2 is provided with a first fixing belt hole 27 , and the second supporting board 3 is provided with a second fixing belt hole 37 .

One end of the fixing strap 1 is fixedly connected to the first fixing strap hole 27 , and the other end of the fixing strap 1 is fixedly connected to the second fixing strap hole 37 .

The fixing belt 1 is a flat and wide structure. the

The fixing belt 1 can be a Velcro, and the flexible surface of the Velcro is used as a strap, which is closely attached to the experimental animal, and is bonded and fixed from the shoulder and hip joint of the animal to the bottom of the main body of the fixing groove.

The arc-shaped supporting plate is provided with a straight bar 28 along its width direction on its upper surface.

The straight rod 28 can be made of materials such as metal, wood, stainless steel, or rubber, and can be used for animals to gnaw in experiments, which conforms to the gnawing habits of animals.

The base includes a support column 4 and a bottom plate 5 connected to the bottom surface of the support column 4, and the top surface of the support column 4 is connected to the bottom surface of the arc-shaped supporting plate.

The height of described support column is 8cm.

The bottom plate is a cuboid hollow structure.

The preferred embodiment of the utility model creation has been specifically described above, but the utility model creation is not limited to the described embodiment, and those skilled in the art can also Various equivalent modifications or replacements are made, and these equivalent modifications or replacements are all included within the scope defined by the claims of the present application.

Claims (7)

1. large operations area is regained consciousness experimental rat fixture, comprise arc pallet and fixing band, it is characterized in that: described arc pallet is respectively provided with two grooves in the both sides of its width, arc pallet is connected and fixed band (1), the radial direction of described fixing band (1) arcuately supporting plate to it around at least one week;

The bottom of described arc pallet is configured with base.

2. large operations area according to claim 1 is regained consciousness experimental rat fixture, it is characterized in that: described arc pallet comprises the first supporting plate (2) and the second supporting plate (3), forms sliding connection structure between the first supporting plate (2) and the second supporting plate (3) along respective length direction;

Two grooves of described arc pallet both sides are specially: the first supporting plate (2) is provided with the first groove (21) and the second groove (22) in the lateral symmetry of its width, and the second supporting plate (3) is provided with the 3rd groove (31) and the 4th groove (32) in the lateral symmetry of its width.

3. large operations area according to claim 2 is regained consciousness experimental rat fixture, it is characterized in that: described the first supporting plate (2) offers chute (23) in their length direction, the bottom surface of the second supporting plate (3) is fixedly connected with gag lever post (33);

Described gag lever post (33) makes the first supporting plate (2) and the second supporting plate (3) be formed through described chute (23) to be slidably connected, and gag lever post (33) carries out coordinating with the nut (24) be located at bottom the first supporting plate (2) locates.

4. the large operations area according to Claims 2 or 3 is regained consciousness experimental rat fixture, it is characterized in that: described the first supporting plate (2) at the dual-side of its length direction along being respectively equipped with the first zigzag hollow slots (25) and the second zigzag hollow slots (26);

Described second supporting plate (3) is respectively equipped with the first plug-in unit (35) and the second plug-in unit (36) on the dual-side edge of its length direction;

Described first plug-in unit (35) and the second plug-in unit (36) are corresponding respectively to be made the first supporting plate (2) and the second supporting plate (3) be formed through described first zigzag hollow slots (25) and the second zigzag hollow slots (26) to be slidably connected.

5. large operations area according to claim 2 is regained consciousness experimental rat fixture, it is characterized in that: described the first supporting plate (2) offers the first fixed belt hole (27), and the second supporting plate (3) offers the second fixed belt hole (37);

One end of described fixing band (1) is fixedly connected on the first fixed belt hole (27), and the other end of fixing band (1) is fixedly connected on the second fixed belt hole (37).

6. large operations area according to claim 1 is regained consciousness experimental rat fixture, it is characterized in that: the one end on described arc pallet surface is thereon provided with straight-bar (28) along its width.

7. large operations area according to claim 1 is regained consciousness experimental rat fixture, it is characterized in that: described base comprises support post (4) and is connected to the base plate (5) of support post (4) bottom surface, the end face of described support post (4) connects the bottom surface of arc pallet.