CN206403765U - A kind of wireless blood flow reserve fraction measurement system - Google Patents

Abstract

The utility model discloses a kind of wireless blood flow reserve fraction measurement system, including：Sensor unit, collection transmitter unit and processing terminal, wherein, sensor unit includes：First pressure sensor unit and second pressure sensor；First pressure sensor unit includes：First pressure sensor and Pressure wire, one end of Pressure wire are connected with the collection transmitter unit, and the other end is provided with first pressure sensor, first pressure sensor and collection transmitter unit wireless connection；Second pressure sensor integration is on collection transmitter unit or is connected on collection transmitter unit；Processing terminal is connected with collection transmitter unit, and blood flow reserve fraction is obtained for receiving the pressure data that collection transmitter unit is gathered, and processing being carried out to it.The measurement of aortic pressure and lesion narrow remote end pressure is integrated in same collection transmitter unit by the utility model, is simplified existing equipment volume and connection to maximization, is added operation technique space.

Description

A Wireless Fractional Blood Flow Reserve Measurement System

technical field

The utility model relates to the field of blood flow reserve fraction measurement, in particular to a wireless blood flow reserve fraction measurement system.

Background technique

In 1993, Professor Nico Pijls of the Netherlands proposed Fractional Flow Reserve (FFR), which is the maximum blood flow that can be obtained by the myocardial region supplied by the coronary artery and the maximum blood flow that the same region can theoretically obtain under normal conditions. The ratio of epicardial vessels is a specific index of epicardial vascular stenosis, and is not affected by factors such as heart rate, blood pressure and peripheral microcirculation. significance.

Currently, the commonly used systems and methods for measuring FFR are: using an interventional catheter (guiding catheter) to measure the aortic pressure (Pa), and using an interventional guide wire (pressure guide wire) to measure the pressure (Pd) at the distal end of the lesion stenosis. Among them, the pressure sensor for the aortic pressure Pa test is fixed on the external host, and the coronary blood flow is guided into the pressure sensor through the interventional catheter for measurement; the pressure sensor for the stenosis distal pressure Pd test is packaged on the pressure guide wire, through the interventional catheter to guide the coronary blood flow into the pressure sensor for measurement; During surgery, the lesion area is entered through a guiding catheter for pressure measurement. The measurement data of the stenosis distal pressure (Pd) is also connected to the host through the cable, and then the host calculates the corresponding FFR value according to the measured Pa and Pd results, and displays Pa, Pd waveform and FFR value in real time. In addition, when using the instantaneous Wave-free Ratio (iFR, instantaneous Wave-free Ratio) in a non-maximal hyperemia state for measurement, the host needs to be connected to external devices such as ECG (electrocardiogram). Therefore, the connection of the system equipment is complicated, and the movement and operation are inconvenient. In order to overcome the above problems, some FFR manufacturers have proposed a method of wirelessly transmitting the Pd data measured by the pressure guide wire. -BOX is delivered to the host again, such as ST. Jude Medical (St. Jude Medical Company). However, the measurement of aortic pressure (Pa) and the connection of external devices such as ECG all need to be connected or wirelessly transmitted to the host. The structure of the actual system is complicated and the operation is inconvenient.

Utility model content

Aiming at the problems existing in the above-mentioned prior art, the utility model proposes a wireless blood flow reserve fraction measurement system. The measurement of the aortic pressure and the pressure at the distal end of lesion stenosis are integrated in the same acquisition and emission unit, which greatly simplifies the actual There is equipment volume and line connection, which increases the operating space.

In order to solve the problems of the technologies described above, the utility model is achieved through the following technical solutions:

The utility model provides a wireless blood flow reserve fraction measurement system, which includes: a sensor unit, an acquisition and emission unit, and a processing terminal, wherein,

The sensor unit includes: a first pressure sensor unit and a second pressure sensor;

The first pressure sensor unit includes: a first pressure sensor and a pressure guide wire, one end of the pressure guide wire is connected to the acquisition and emission unit, and the other end of the pressure guide wire is provided with the first pressure sensor, The first pressure sensor is wirelessly connected to the acquisition and transmission unit, and the first pressure sensor is used to measure the pressure at the distal end of the lesion stenosis, and transmit the pressure at the distal end of the lesion stenosis to the acquisition and transmission unit;

The second pressure sensor is integrated on the acquisition transmitter unit or connected to the acquisition transmitter unit, the second pressure sensor is used to measure the aortic pressure, and transmit the aortic pressure to the acquisition transmitter unit unit;

The processing terminal is connected to the collection and transmission unit, and the processing terminal is used to receive the pressure at the distal end of the lesion stenosis and the aortic pressure transmitted by the collection and transmission unit, and process them to obtain the blood flow reserve Fraction.

Preferably, the collecting and transmitting unit further includes: an electrocardiogram data interface, which is used to connect to an external device, and then receive the electrocardiogram signal of the external device.

Preferably, one end of the pressure guidewire is also provided with: a temperature measurement unit and/or a Doppler measurement unit, and the temperature measurement unit and/or the Doppler measurement unit are wirelessly connected to the acquisition and emission unit ;

The temperature measurement unit is used to measure the temperature value of the stenosis distal end of the lesion, and transmit the temperature value to the acquisition and emission unit;

The Doppler measurement unit is used to measure blood flow Doppler data at the distal end of the lesion stenosis, and transmit the blood flow Doppler data to the acquisition and emission unit.

Preferably, the processing terminal is further configured to receive the temperature value and/or blood flow Doppler data through the acquisition and transmitting unit, and perform calculations based on the temperature value and blood flow Doppler data to obtain blood flow Storage Index and/or Microcirculatory Resistance Index.

The acquisition and transmission unit includes: a pressure sensor modulation circuit, an acquisition unit, an analog-to-digital converter, and a transmission unit,

The pressure sensor modulation circuit is used to provide the voltage reference required for the operation of the first pressure sensor and the second pressure sensor, convert the obtained voltage signal to an appropriate ADC working range, and reduce the clutter in the voltage signal interference;

The acquisition unit, the analog-to-digital converter, and the transmitting unit are connected in sequence, and the acquisition unit is used to acquire the pressure at the distal end of the lesion stenosis and the aortic pressure; the analog-to-digital converter is used to monitor the The pressure at the distal end of the lesion stenosis and the pressure at the aorta collected by the acquisition unit are converted into analog-to-digital; The pressure is transmitted to the processing terminal.

Preferably, the processing terminal further includes: a display unit, configured to display the pressure at the distal end of the lesion stenosis, the aortic pressure, and the blood flow reserve fraction in real time.

Preferably, the connection between the collection and transmission unit and the processing terminal is a wireless connection and/or a wired connection;

When it is a wireless connection, the collecting and transmitting unit includes: a wireless transmitting unit, and the processing terminal includes a wireless receiving unit;

When it is a wired connection, both the collection and transmission unit and the processing terminal include a data connection interface.

Preferably, the wireless transmitting unit and the wireless receiving unit are: one or more of a WIFI transmission unit, a Bluetooth transmission unit, a GPRS transmission unit, a WCDMA transmission unit, and a digital wireless transmission station.

Preferably, the first pressure sensor and the second pressure sensor are respectively: any one of piezoresistive pressure sensors, capacitive pressure sensors, optical pressure sensors, magnetic pressure sensors, and piezoelectric pressure sensors.

Preferably, the power supply unit of the collection and transmission unit is a built-in battery and/or an external power supply.

Preferably, the built-in battery is a lithium battery, a nickel metal hydride battery or a rechargeable battery.

Preferably, the processing terminal is specifically one of: a PC computer, a tablet computer, a large-screen mobile phone, a mobile notebook, or an ultrasonic device.

Compared with the prior art, the utility model has the following advantages:

(1) The wireless blood flow reserve fraction measurement system provided by the utility model integrates the pressure guide wire and the second pressure sensor on the same acquisition and emission unit, and can uniformly send the aortic pressure and the pressure at the distal end of the lesion stenosis to the processing terminal for processing. It overcomes the problems of existing FFR equipment that must be connected by wire or a separate pressure wire wirelessly transmits data, which is difficult to synchronize and high cost, effectively simplifies the difficulty of equipment operation, reduces the space occupied by the equipment, and reduces the number and length of equipment connections;

(2) The wireless blood flow reserve fraction measurement system of the present utility model can be used as a functional module of existing medical diagnosis/treatment equipment, such as: it can be built-in or externally installed in the existing intravascular ultrasonic imaging system, and only needs to be installed in the existing Add FFR-related algorithms or software to the intravascular ultrasound imaging system, so that it can observe both intravascular ultrasound images and FFR values, so as to realize the combination of vascular structural imaging and stenosis function evaluation, and reduce the number of surgical examinations for patients. Time and cost, and provide rich and comprehensive information for doctors to make clinical diagnosis and treatment plan, improve the accuracy and reliability of the diagnosis of related cardiovascular diseases.

Of course, any product implementing the present utility model does not necessarily need to achieve all the above-mentioned advantages at the same time.

Description of drawings

Below in conjunction with accompanying drawing, the embodiment of the present utility model is further described:

FIG. 1 is a schematic structural diagram of a wireless fractional blood flow reserve measurement system according to Embodiment 1 of the present invention;

2 is a schematic structural diagram of a wireless fractional blood flow reserve measurement system in a preferred embodiment of the present invention;

FIG. 3 is a schematic structural diagram of a wireless fractional blood flow reserve measurement system according to Embodiment 2 of the present invention.

Explanation of symbols: 1-sensor unit, 2-acquisition and emission unit, 2-processing terminal;

11-first pressure sensor unit, 12-second pressure sensor, 13-temperature measurement unit, 14-Doppler measurement unit;

111-pressure guide wire, 112-the first pressure sensor;

21 - Electrocardiogram data interface.

detailed description

The following is a detailed description of the embodiments of the present utility model. This embodiment is implemented on the premise of the technical solution of the present utility model, and detailed implementation methods and specific operating procedures are provided, but the protection scope of the present utility model is not limited to the following the described embodiment.

Example 1:

In conjunction with FIG. 1, the wireless blood flow reserve fraction measurement system of the present invention is described in detail. Its structural diagram is shown in FIG. 1, which includes: a sensor unit 1, an acquisition and emission unit 2 and a processing terminal 3. A pressure sensor unit 11 and a second pressure sensor 12, the first pressure sensor unit 11 includes: a pressure guide wire 111 and a first pressure sensor 112, one end of the pressure guide wire 111 is connected to the acquisition and emission unit 2, the pressure guide wire 112 The other end is provided with a first pressure sensor 112, the first pressure sensor 112 is wirelessly connected with the collection and transmission unit 2, the first pressure sensor 112 is used to measure the pressure Pd at the distal end of the lesion stenosis, and wirelessly transmit the measured pressure at the distal end of the lesion stenosis To the collection and transmission unit 2; the second pressure sensor 12 is integrated on the collection and transmission unit 2, used to measure the aortic pressure Pa by means of the guide catheter, and transmit the measured aortic pressure to the collection and transmission unit 2; the processing terminal 3 and the collection The transmitting unit 2 is connected to receive and collect the distal pressure of the lesion stenosis and the aortic pressure of the transmitting unit 2, and process them to obtain the fractional blood flow reserve FFR=Pd/Pa.

In a preferred embodiment, the second pressure sensor 12 can be connected to the acquisition and emission unit 2 through a data line, extending a certain distance, so as to facilitate the docking of the second pressure sensor 12 with the guide catheter, and to facilitate the maintenance or replacement of the second pressure sensor 12 Wait.

In a preferred embodiment, the acquisition and transmission unit 2 includes: a pressure sensor modulation circuit, an acquisition unit, an analog-to-digital converter, and a transmission unit. The pressure sensor modulation circuit is used to provide the voltage reference required for the pressure sensor to work, and convert the obtained voltage signal To the appropriate ADC working range, reduce the interference of clutter in the voltage signal; the acquisition unit, the analog-to-digital converter and the transmitting unit are connected in sequence, and the acquisition unit is used to collect the pressure at the distal end of the lesion stenosis and the aortic pressure; the analog-to-digital converter is used to collect The pressure at the distal end of the lesion stenosis and the aortic pressure collected by the unit perform analog-to-digital conversion; the transmitting unit is used to transmit the pressure at the distal end of the lesion stenosis and the aortic pressure converted by the analog-to-digital converter to the processing terminal.

In a preferred embodiment, the other end of the pressure guide wire is also provided with: a temperature measurement unit and/or a Doppler measurement unit, the temperature measurement unit and/or the Doppler measurement unit are wirelessly connected to the acquisition and emission unit, and its structural diagram is as follows As shown in Figure 2; the temperature measurement unit is used to measure the temperature value of the distal end of the lesion stenosis, and transmits the temperature value to the acquisition and emission unit; the Doppler measurement unit is used to measure the blood flow Doppler data of the distal end of the lesion stenosis, and The blood flow Doppler data is transmitted to the acquisition and emission unit. The collection and transmission unit transmits the collected temperature value and/or blood flow Doppler data to the processing terminal 3, and the processing terminal 3 processes it to obtain a blood flow storage index (CFR, Coronary Flow Reserve) and/or a microcirculation resistance index (IMR, Index of Microcirculatory Resistance).

In a preferred embodiment, the processing terminal 3 further includes: a display unit for displaying the pressure at the distal end of the lesion stenosis, the aortic pressure and the blood flow reserve fraction in real time.

In different embodiments, the connection mode between the collecting and transmitting unit 2 and the processing terminal 3 can be a wireless connection or a wired connection. When it is a wireless connection, it can be: WIFI transmission, Bluetooth transmission, GPRS transmission, WCDMA transmission or digital wireless One or more combinations of data transmission stations, etc.

In different embodiments, the processing terminal 3 can be any one of a PC computer, a tablet computer, a large-screen mobile phone, a mobile notebook, or a dedicated ultrasound device (such as an intravascular ultrasound imaging system).

In different embodiments, the first pressure sensor and the second pressure sensor may be any one of piezoresistive pressure sensor, capacitive pressure sensor, optical pressure sensor, magnetic pressure sensor and piezoelectric pressure sensor respectively.

In different embodiments, the power supply of the collecting and transmitting unit 2 can be a built-in battery, or can be connected to an external power supply through a USB interface or a socket. The built-in battery can be lithium battery, nickel metal hydride battery or rechargeable battery etc.

Example 2:

This embodiment is on the basis of embodiment 1, has increased electrocardiogram (ECG) interface on the collecting and transmitting unit 2, is used to connect the ECG signal of external equipment, structural schematic diagram is as shown in Figure 3, and collecting and transmitting unit 2 narrows the lesion Remote pressure, aortic pressure and ECG signals are uniformly sent to the processing terminal 3, so that the FFR can be obtained by measuring the instantaneous Wave-free Ratio (iFR, instantaneous Wave-free Ratio) of the non-maximal hyperemia state, that is, during the no-wave period ( wave freeperiod) measured instantaneous pressure FFR value.

What is disclosed here is only the preferred embodiment of the utility model. This specification selects and describes these embodiments in detail to better explain the principle and practical application of the utility model, not to limit the utility model. Any modifications and changes made by those skilled in the art within the scope of the description shall fall within the protection scope of the present utility model.

Claims (11)

1. A wireless blood flow reserve fraction measurement system, characterized in that it comprises: a sensor unit, an acquisition and emission unit and a processing terminal, wherein, The sensor unit includes: a first pressure sensor unit and a second pressure sensor; The first pressure sensor unit includes: a first pressure sensor and a pressure guide wire, one end of the pressure guide wire is connected to the acquisition and emission unit, and the other end of the pressure guide wire is provided with the first pressure sensor, The first pressure sensor is wirelessly connected to the acquisition and transmission unit, and the first pressure sensor is used to measure the pressure at the distal end of the lesion stenosis, and transmit the pressure at the distal end of the lesion stenosis to the acquisition and transmission unit; The second pressure sensor is integrated on the acquisition transmitter unit or connected to the acquisition transmitter unit, the second pressure sensor is used to measure the aortic pressure, and transmit the aortic pressure to the acquisition transmitter unit unit; The processing terminal is connected to the collection and transmission unit, and the processing terminal is used to receive the pressure at the distal end of the lesion stenosis and the aortic pressure transmitted by the collection and transmission unit, and process them to obtain the blood flow reserve Fraction. 2 . The wireless fractional blood flow reserve measurement system according to claim 1 , wherein the collection and transmission unit further comprises: an electrocardiogram data interface, which is used to connect to an external device, and then receive the electrocardiogram signal of the external device. 3 . 3. The wireless fractional blood flow reserve measurement system according to claim 1, wherein the other end of the pressure guide wire is also provided with: a temperature measurement unit and/or a Doppler measurement unit, and the temperature measurement unit And/or the Doppler measurement unit is wirelessly connected to the acquisition and transmission unit; The temperature measurement unit is used to measure the temperature value of the stenosis distal end of the lesion, and transmit the temperature value to the acquisition and emission unit; The Doppler measurement unit is used to measure blood flow Doppler data at the distal end of the lesion stenosis, and transmit the blood flow Doppler data to the acquisition and emission unit. 4. The wireless fractional blood flow reserve measurement system according to claim 3, wherein the processing terminal is further configured to receive the temperature value and/or blood flow Doppler data through the collection and transmission unit, and The blood flow storage index and/or the microcirculation resistance index are obtained by calculating according to the temperature value and the blood flow Doppler data. 5. The wireless fractional blood flow reserve measurement system according to claim 1, wherein the collection and transmission unit comprises: a pressure sensor modulation circuit, a collection unit, an analog-to-digital converter, and a transmission unit, The pressure sensor modulation circuit is used to provide the voltage reference required for the operation of the first pressure sensor and the second pressure sensor; The acquisition unit, the analog-to-digital converter, and the transmitting unit are connected in sequence, and the acquisition unit is used to acquire the pressure at the distal end of the lesion stenosis and the aortic pressure; the analog-to-digital converter is used to monitor the The pressure at the distal end of the lesion stenosis and the pressure at the aorta collected by the acquisition unit are converted into analog-to-digital; The pressure is transmitted to the processing terminal. 6. The wireless blood flow reserve measurement system according to claim 1, wherein the processing terminal further comprises: a display unit for displaying the pressure at the distal end of the lesion stenosis, the aortic pressure and the The blood flow reserve fraction is displayed in real time. 7. The wireless blood flow reserve measurement system according to claim 1, wherein the connection between the collection and transmission unit and the processing terminal is a wireless connection and/or a wired connection; When it is a wireless connection, the collecting and transmitting unit includes: a wireless transmitting unit, and the processing terminal includes a wireless receiving unit; When it is a wired connection, both the collection and transmission unit and the processing terminal include a data connection interface. 8. The wireless blood flow reserve fraction measurement system according to claim 7, wherein the wireless transmitting unit and the wireless receiving unit are: a WIFI transmission unit, a Bluetooth transmission unit, a GPRS transmission unit, a WCDMA transmission unit, One or more of digital radio transmission stations. 9. The wireless blood flow reserve fraction measurement system according to claim 1, wherein the first pressure sensor and the second pressure sensor are respectively: a piezoresistive pressure sensor, a capacitive pressure sensor, an optical pressure sensor Any one of sensors, magnetic pressure sensors, and piezoelectric pressure sensors. 10 . The wireless fractional blood flow reserve measurement system according to claim 1 , wherein the power supply unit of the collection and transmission unit is a built-in battery and/or an external power supply. 11 . 11. The wireless fractional blood flow reserve measurement system according to claim 1, wherein the processing terminal is specifically one of: a PC computer, a tablet computer, a large-screen mobile phone, a mobile notebook, or an ultrasound device.