CN206151974U - Hemoperfusion apparatus - Google Patents
Hemoperfusion apparatus Download PDFInfo
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- CN206151974U CN206151974U CN201620938610.0U CN201620938610U CN206151974U CN 206151974 U CN206151974 U CN 206151974U CN 201620938610 U CN201620938610 U CN 201620938610U CN 206151974 U CN206151974 U CN 206151974U
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- cylinder
- perfusion device
- divided
- spiral cover
- end cap
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- 230000001951 hemoperfusion Effects 0.000 title abstract 2
- 230000008676 import Effects 0.000 claims abstract description 24
- 230000007704 transition Effects 0.000 claims abstract description 16
- 238000001914 filtration Methods 0.000 claims description 51
- 230000008081 blood perfusion Effects 0.000 claims description 32
- 239000012528 membrane Substances 0.000 claims description 20
- 238000011144 upstream manufacturing Methods 0.000 claims description 6
- 210000002435 tendon Anatomy 0.000 claims description 5
- 239000011148 porous material Substances 0.000 claims description 4
- 230000003467 diminishing effect Effects 0.000 claims description 3
- 238000003491 array Methods 0.000 claims description 2
- 230000010412 perfusion Effects 0.000 abstract description 27
- 238000007789 sealing Methods 0.000 abstract description 13
- 238000000034 method Methods 0.000 abstract description 7
- 239000012530 fluid Substances 0.000 abstract 1
- 210000002445 nipple Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 28
- 210000004369 blood Anatomy 0.000 description 28
- 230000017531 blood circulation Effects 0.000 description 10
- 239000003463 adsorbent Substances 0.000 description 9
- 239000007787 solid Substances 0.000 description 7
- 238000000746 purification Methods 0.000 description 6
- 239000004677 Nylon Substances 0.000 description 5
- 229920001778 nylon Polymers 0.000 description 5
- 229920001971 elastomer Polymers 0.000 description 4
- 230000023555 blood coagulation Effects 0.000 description 3
- 238000002844 melting Methods 0.000 description 3
- 230000008018 melting Effects 0.000 description 3
- 238000001179 sorption measurement Methods 0.000 description 3
- 238000009826 distribution Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000002969 morbid Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 241000883990 Flabellum Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000008338 local blood flow Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
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- External Artificial Organs (AREA)
Abstract
The utility model provides a hemoperfusion apparatus, the novel nipple rectifier comprises a cylindrical shel, barrel one end closes up for the circular arc transition, the center of closing up is for exporting luer connector, this export luer connector's import department is equipped with output filter equipment, export luer connector and first spiral cover screw -thread fit, the other end of barrel is uncovered, this open inner wall is equipped with the ring channel, a split -flow filter device is located in this ring channel, and compress tightly fixedly through an end cover, the center of end cover is equipped with imported luer connector, the center of split -flow filter device is equipped with bellied hemispherical reposition of redundant personnel awl, it overflows clearance D to leave between import luer connector's low reaches drill way and hemispherical reposition of redundant personnel are bored, import luer connector and second spiral cover screw -thread fit. The utility model discloses simple structure, convenient to use, sealing performance are good, have good fluid dynamics design, effectively avoid perfusion process gassing.
Description
Technical field
The utility model is related to medical instruments field, more particularly to a kind of blood perfusion device.
Background technology
Blood perfusion is that blood samples of patients is introduced in the perfusion device equipped with solid adsorbent by extracorporeal circulation apparatus, is removed
Endogenous or exogenous morbid substance in blood, and by a kind for the treatment of method in defeated time patient's body of the blood after purification.It is interior
The blood perfusion device of dress solid adsorbent is the important composition part of blood purification treatment device, it is desirable to good sealing
And blood compatibility, and it is easy to industrialization large-scale production.
But, blood perfusion device common at present, such as Chinese utility model patent ZL200820047979.8 and China's reality
With blood perfusion device disclosed in new patent ZL201010183145.1, it is vertical dead that inner barrel is particularly blood exit port
The zig zag structure of angle/nearly vertical angle, the blood perfusion device of this class formation has the disadvantage that in use：First, pole
It is easily caused blood and vortex is formed in flow process, impact is produced on the rheological equationm of state of blood, causes the malignant conditions such as blood coagulation to be sent out
It is raw；2nd, it is unfavorable for that the bubble produced in perfusion device is discharged, and there is bubble in blood will directly threaten patient vitals' safety, make
Obtaining medical personnel need to spend more time and energy to exclude bubble when using this kind of perfusion device；3rd, perfusion device arrival end
Nearer apart from filter screen, blood cannot enter cylinder with more uniform speed and flow during perfusion, and blood flow enters cylinder in shape of gushing
In vivo, the velocity of blood flow near cylinder central authorities is comparatively fast slower near the velocity of blood flow of barrel, causes blood easily to produce vortex,
It is unfavorable for that blood is fully contacted with the solid adsorbent in cylinder, causing the adsorption efficiency of perfusion device reduces；4th, perfusion device assembly
Quantity is more, the mode such as coordinates to combine by embedded, screw thread from more than ten components so that perfusion device in sterilization, transport etc.
During sealing property decline, be highly prone to secondary pollution, also, component count excessively also results in complex manufacturing, life
Produce relatively costly.
To solve the above problems, people have carried out numerous studies design to perfusion device.Such as, Chinese utility model patent
ZL201420847160.5 discloses a kind of blood perfusion device with drainage stent, by arranging drainage rack in cylinder（Including
Middle mandrel rod, flow distribution plate and shunting flabellum）Shunting is played a part of to blood, additionally, also researcher is by perfusion device porch
Fitting passage makes screw type pipeline, and blood is entered in perfusion device by helical pipe along perfusion wall.Although these structures
The generation of blood vortex is reduced to a certain extent, but all there are problems that volume is larger, structure, particularly such as
Fruit process it is improper cause parts surface coarse, easily cause the visible component in blood in quick flow process due to friction etc.
Reason is destroyed.
Therefore, from perfusion device operability is improved, application risk is reduced, improves cylinder hydrodynamic characteristics, improves perfusion
Efficiency and simplified structural complexity angularly set out, and the improvement for carrying out major design to existing perfusion device is very necessary.
The content of the invention
The purpose of this utility model is for the deficiencies in the prior art, there is provided a kind of blood perfusion device, its simple structure, is made
With convenient, good seal performance, with good fluid-dynamic design, it is prevented effectively from perfusing course and produces bubble.
The technical solution of the utility model is：A kind of blood perfusion device, including cylinder, described cylinder one end is arc transition
Close up, the center of closing in is outlet luer joint, and the entrance of the outlet luer joint is provided with output filtering device, the output
The pore size filter of filter is 20～100 μm or 100～300 μm, and the outlet luer joint and the first spiral cover screw thread coordinate,
The other end of the cylinder is open, and the open inwall is provided with the cannelure for installing divided-flow filtering apparatus, and one shunted
Filter device is fixed in the cannelure by an end cap, and the center of the end cap is provided with import female Luer, described
The center of divided-flow filtering apparatus is provided with the hemispherical spreader of a projection, and the radius of the hemispherical spreader is 2～5mm, described
The downstream orifice of hemispherical spreader correspondence import female Luer, the downstream orifice of import female Luer and hemispherical spreader it
Between leave excessively stream clearance D, the excessively stream clearance D is 1～18mm, and the import female Luer coordinates with the second spiral cover screw thread.
The inner chamber of the cylinder is internal diameter from opening end to the diminishing conical cavities in closing in end.
The segmental arc central angle alpha that cylinder arc transition closes up is 30～90 °.
The divided-flow filtering apparatus include support frame and filter membrane, and the support frame has ring frame and is fixed on
Many support spokes of ring frame bottom, it is each to support spoke to be cambered surface, the filter membrane and each support towards the one side of end cap
Spoke, ring frame are fixedly connected, positioned at the bottom surface of support frame.
Also including the annular flow deflector of polylith different-diameter, these annular flow deflectors are in concentric circles to the divided-flow filtering apparatus
Arrangement be fixed on many support spokes on, between hemispherical spreader and ring frame, each annular flow deflector it is following to
Angle γ between outer incline, and the filter membrane of bottom is 10～60 °.
The divided-flow filtering apparatus include support frame and filter membrane, and the support frame has ring frame and is fixed on
The filter plate of ring frame bottom, the filter plate is provided with some vias, and the filter membrane is fixed on below filter plate.
It is respectively equipped with the arc transition closing in end end face of the cylinder, end cap convex around multiple retainings of female Luer
Point, is respectively equipped with the retaining groove coordinated with retaining salient point in first spiral cover, the axial end of the second spiral cover.
The open outer wall of the cylinder is provided with external thread section, and the end cap coordinates the upstream for being fixed on cylinder by screw thread
End, divided-flow filtering apparatus are pressed abd fixed in the cannelure of cylinder, and between the end cap and divided-flow filtering apparatus annular is provided with
Sealing ring.
The end face of the end cap is plane, or for the conical surface, the vertex of a cone angle β of the conical surface is 145～175 °.
Second spiral cover, the first spiral cover, it is respectively equipped with anti-skidding convex tendon on the circumference side of end cap.
Using above-mentioned technical proposal：A kind of blood perfusion device, including cylinder, described cylinder one end is arc transition closing in,
The center of closing in is outlet luer joint, and the entrance of the outlet luer joint is provided with output filtering device, the output filtering
The pore size filter of device is 20～100 μm or 100～300 μm, and wherein output filtering device is set to 20～100 μm of filter bores
Footpath is applied to plasma perfusion, prevents the solid adsorbent fine particle for coming off from flowing out perfusion device, is set to 100～300 μm of mistake
Filter opening footpath is applied to whole blood perfusion, both can guarantee that the visible components such as haemocyte were passed through, and can prevent the solid adsorbant for coming off
Agent particle flows out perfusion device.The outlet luer joint and the first spiral cover screw thread coordinate, and outlet luer joint is used for and standard blood
Liquid purification pipeline quickly connects, and the first spiral cover that screw thread coordinates plays sealing during transport, storage to the downstream of cylinder
Effect, the first spiral cover is screwed out when using, you can is used, is facilitated medical personnel to operate.The downstream of cylinder is arc transition closing in,
The hydrodynamic characteristics of cylinder can be effectively improved, the generation of blood vortex is reduced, while also discharge beneficial to medical personnel producing
A small amount of bubble.The other end of the cylinder is open, and the open inwall is provided with the annular for installing divided-flow filtering apparatus
Groove a, divided-flow filtering apparatus are fixed in the cannelure by an end cap, and the center of the end cap is provided with import Shandong
That joint, the center of the divided-flow filtering apparatus is provided with the hemispherical spreader of a projection, and the radius of the hemispherical spreader is 2
～5mm, the downstream orifice of the hemispherical spreader correspondence import female Luer, the downstream orifice and hemisphere of import female Luer
Leave excessively stream clearance D between shape spreader, the excessively stream clearance D is 1～18mm, when blood perfusion is carried out, blood is via entering
Mouth female Luer is injected in the barrel chamber of perfusion device, to hemispherical shunting poppet surface shunting, makes blood along excessively stream clearance D uniform flow
Enter barrel chamber, uniform contact abundant with the solid adsorbent in barrel chamber can effectively improve the adsorption efficiency of adsorbent, while ensureing
Velocity of blood flow is uniform, it is to avoid produces vortex because local blood flow velocity is too fast, effectively reduces bubble.The import female Luer and the
Two spiral cover screw threads coordinate, and the second spiral cover is sealed to import female Luer, and the upstream end of cylinder keeps close during transporting, storing
Envelope state, the second spiral cover is screwed out when using, you can is used, is facilitated medical personnel to operate.
The inner chamber of the cylinder is internal diameter from opening end to the diminishing conical cavities in closing in end, makes blood flow unimpeded, is subtracted
The appearance of the problems such as few bubble, blood coagulation.
The divided-flow filtering apparatus include support frame and filter membrane, and the support frame has ring frame and is fixed on
Many of ring frame bottom support spokes, it is each to support spoke to be cambered surface towards the one side of end cap, each support spoke of cambered surface with
Hemispherical spreader synergy, forms to blood and shunts, it is ensured that velocity of blood flow is uniform, the filter membrane and each support spoke,
Ring frame is fixedly connected, and positioned at the bottom surface of support frame, being arranged on the filter membrane of support frame bottom surface can be in filtering blood
Impurity, while smashing a small amount of bubble produced in support frame, make in the blood of divided-flow filtering apparatus not bubbles, protect
Card blood perfusion safety.
Also including the annular flow deflector of polylith different-diameter, these annular flow deflectors are in concentric circles to the divided-flow filtering apparatus
Arrangement be fixed on many support spokes on, between hemispherical spreader and ring frame, each annular flow deflector it is following to
Angle γ between outer incline, and the filter membrane of bottom is 10～60 °, and these annular flow deflectors make blood with uniform flow velocity stream
Cross divided-flow filtering apparatus, it is to avoid velocity of blood flow in the middle part of the cylinder is too fast and velocity of blood flow of near barrel is excessively slow and produce gas
Bubble.
It is respectively equipped with the arc transition closing in end end face of the cylinder, end cap convex around multiple retainings of female Luer
Point, is respectively equipped with the retaining groove coordinated with retaining salient point in first spiral cover, the axial end of the second spiral cover, when the first rotation
When lid, the second spiral cover are tightened on respectively outlet luer joint, import female Luer, corresponding retaining salient point snaps in corresponding retaining
In groove, prevent the first spiral cover, the second spiral cover from unclamping naturally or come off because unexpected, it is ensured that transport, store during perfusion device
Sealing property.
The open outer wall of the cylinder is provided with external thread section, and the end cap coordinates the upstream for being fixed on cylinder by screw thread
End, divided-flow filtering apparatus are pressed abd fixed in the cannelure of cylinder, and between the end cap and divided-flow filtering apparatus annular is provided with
Sealing ring, end cap coordinates the upstream end for being fixed on cylinder by screw thread, is conveniently put into or changes solid adsorbent, the annular of setting
Sealing ring can be effectively ensured the sealing property of perfusion device cylinder.
It is further described with reference to the accompanying drawings and detailed description.
Description of the drawings
Fig. 1 is structural representation of the present utility model；
Fig. 2 is the sectional view of Fig. 1；
Fig. 3 is the structural representation of the utility model cylinder；
Fig. 4 is the sectional view of Fig. 3；
Fig. 5 is the structural representation of the utility model output filtering device；
Fig. 6 is the sectional view of Fig. 5；
Fig. 7 is the structural representation of the utility model end cap；
Fig. 8 is the sectional view of Fig. 7；
Fig. 9 is the structural representation of the utility model divided-flow filtering apparatus；
Figure 10 is the sectional view of Fig. 9；
Figure 11 is the structural representation of the end cap of the utility model embodiment two；
Figure 12 is the structural representation of the divided-flow filtering apparatus of the utility model embodiment three；
Figure 13 is the sectional view of Figure 12；
Figure 14 is the structural representation of the utility model example IV divided-flow filtering apparatus；
Figure 15 is the sectional view of Figure 14；
Figure 16 is the structural representation of the cylinder of the utility model embodiment five；
Figure 17 is the sectional view of Figure 16；
Figure 18 is the structural representation of the end cap of the utility model embodiment five.
In accompanying drawing, 1 is cylinder, and 2 is outlet luer joint, and 3 is output filtering device, and 4 is the first spiral cover, and 5 is cannelure,
6 is divided-flow filtering apparatus, and 61 is support frame, and 61a is ring frame, and to support spoke, 61c is filter plate to 61b, and 62 are filtration
Film, 63 are annular flow deflector, and 7 is end cap, and 8 is hemispherical spreader, and 9 is import female Luer, and 10 is the second spiral cover, and 11 is rubber
Glue sealing gasket, 12 is retaining salient point, and 13 is retaining groove, and 14 is O-ring seal, and 15 is anti-skidding convex tendon, and 16 is rotation stop limiting stand
Rank.
Specific embodiment
Embodiment one：
Referring to Fig. 1 to Figure 10, blood perfusion device includes cylinder 1, and the one end of cylinder 1 is arc transition closing in, in closing in
The heart is outlet luer joint 2, and the other end of cylinder 1 is open, and the inner chamber of cylinder 1 gradually contracts from opening end for internal diameter to closing in end
Little conical cavities, the draw ratio of the cavity is 2:1~5:1, all kinds of solid-state blood purification sorbing materials can be filled in cavity, fill out
Fill volume accounts for barrel chamber volume 65% ~ 95%.The segmental arc central angle alpha that cylinder arc transition closes up is 30～90 °, in the present embodiment,
Center of circle angle α is 60 °.The entrance of outlet luer joint 2 is provided with output filtering device 3, the pore size filter of output filtering device 3
For 20～100 μm or 100～300 μm, in the present embodiment, the output filtering device is by ring frame and by melting or bonding
Or ultrasonic bonding mode is fixed on the nylon wire composition of ring frame bottom, the wherein inner chamber of ring frame is in open top
Greatly, the little tapered bore of bottom opening, the ring frame of output filtering device is by melting or the side of bonding or ultrasonic bonding
Formula is fixed on the arc transition closing in center of cylinder, and nylon wire is located at the bottom at arc transition closing in center, connects with outlet luer
The entrance contact of head, the top circumference of ring frame is flushed with the top of arc transition closing in center, makes cylinder inboard wall to Buddhist nun
In smoothing junction without dead angle between imperial net filtration face, the nylon wire in 20～100 μm of apertures of output filtering device is applied to plasma perfusion,
The nylon wire in 100～300 μm of apertures is applied to whole blood perfusion.The open inwall of cylinder is provided with for installing divided-flow filtering apparatus 6
Cannelure 5, divided-flow filtering apparatus 6 are fixed in the cannelure 5 by an end cap 7, in the present embodiment, institute
State the open outer wall of cylinder 1 and be provided with external thread section, end cap 7 is coordinated the upstream end for being fixed on cylinder 1 by screw thread, will be shunted
Filter device 6 is pressed abd fixed in the cannelure 5 of cylinder 1, is the sealing property for ensureing cylinder opening end, end cap 7 and shunt filtering
O-ring seal 14 is provided between device 6.The center of the end cap 7 is provided with import female Luer 9, the divided-flow filtering apparatus 6
Center be provided with the hemispherical spreader 8 of a projection, the radius of the hemispherical spreader 8 is 2～5mm, the hemispherical shunting
The downstream orifice of 8 corresponding import female Luers 9 is bored, is left between the downstream orifice of import female Luer 9 and hemispherical spreader 8
Excessively stream clearance D, excessively stream clearance D is 1～18mm, and in the present embodiment, the divided-flow filtering apparatus 6 include support frame 61 and filter
Film 62, the support frame 61 has ring frame 61a and is fixed on eight support spoke 61b of ring frame 61a bottoms, respectively
Spoke 61b is supported to be cambered surface towards the one side of end cap, filter membrane 62 is using the nylon wire with output filtering device same size, institute
State filter membrane 62 to consolidate with the bottom of each support spoke 61b, ring frame 61a by way of melting or bonding or ultrasonic bonding
Fixed connection, positioned at the bottom surface of support frame 61, the end face of the end cap is plane, and the circumference of end cap is provided with the outwardly directed ring of axle
Shape is turned back portion, and the turn back outer peripheral sidewall in portion of the annular is provided with anti-skidding convex tendon 15, and the turn back inwall in portion of annular is provided with internal thread segment
External thread section screw thread is provided with the open outer wall of cylinder 1 to coordinate, divided-flow filtering apparatus are assembled in the open cannelure of cylinder,
Filter membrane 62 is located at the bottom land of cannelure, the top surface of ring frame 61a and the end face of cylinder opening end, O-ring seal 14
External diameter and the annular of end cap portion's internal diameter of turning back it is identical, the internal diameter of O-ring seal between the external diameter, internal diameter of ring frame,
The inner periphery for making O-ring seal is located in the ring frame axial end of divided-flow filtering apparatus, has so both met sealing demand,
Blood flow is not interfered.The screw thread of 9 and second spiral cover of import female Luer 10 coordinates, the outlet luer joint 2 and first
The screw thread of spiral cover 4 coordinates, and the first spiral cover, the second spiral cover, is equipped with anti-skidding convex tendon 15 on the circumference side of end cap, is to strengthen sealing
Can, between the spiral cover 4 of the outlet luer joint 2 and first, to be equipped with rubber between the spiral cover 10 of import female Luer 9 and second close
Packing 11, rubber gasket is made using silicon rubber, and it is convex that each rubber gasket is provided with cambered surface towards the one side of respective female Luer
Rise.To prevent the first spiral cover, the second spiral cover because being accidentally unlocked or coming off, the arc transition closing in end end face of the cylinder 1, end cap
The multiple retaining salient points 12 around female Luer are respectively equipped with 7, are divided in first spiral cover 4, the axial end of the second spiral cover 10
Be not provided with retaining salient point 12 coordinate retaining groove 13, by the first spiral cover, the second spiral cover be tightened on respectively outlet luer joint,
In import female Luer, snapping in corresponding retaining groove to each retaining salient point.
Embodiment two：
Referring to Figure 11, the difference of the present embodiment blood perfusion device is the end of the end cap 7 for being arranged on cylinder opening end
Face is the conical surface, and the vertex of a cone angle β of the conical surface is 145～175 °, and in the present embodiment, vertex of a cone angle β is 160 °, remaining structure and reality
Apply example one identical.
Embodiment three：
Referring to Figure 12 and Figure 13, the difference of the present embodiment blood perfusion device is to be arranged on dividing for cylinder opening end
Stream filter 6 includes support frame 61 and filter membrane 62, and the support frame 61 has ring frame 61a and is fixed on annular
The filter plate 61c of housing 61a bottoms, filter plate 61c is provided with some vias, and hemispherical spreader is arranged on the centre bit of filter plate
Put, the filter membrane 62 is fixed on below filter plate 61c, remaining structure is identical with embodiment one.
Example IV：
Referring to Figure 14 and Figure 15, the difference of the present embodiment blood perfusion device is to be arranged on dividing for cylinder opening end
Also including the annular flow deflector 63 of polylith different-diameter, the quantity of annular flow deflector is six to stream filter 6, and these annulars are led
Flow 63 is fixed on many and supports on spoke 61b in concentric arrays, between hemispherical spreader 8 and ring frame 61a,
Each annular flow deflector 63 it is following outward-dipping, and the angle γ between the filter membrane 62 of bottom be 10～60 °, the present embodiment
In, angle γ is 30 °, and remaining structure is identical with embodiment one.
Embodiment five：
Referring to Figure 16 to Figure 18, the difference of the present embodiment blood perfusion device is to arrange in the open outer wall of cylinder
There is the rotation stop limited step 16 of projection, it is circumferentially uniform that rotation stop limited step 16 is provided with two or more towards on the end face of end cap
The retaining salient point 12 of distribution, is 12 in this example, and correspondingly, end cap 7 is provided with retaining groove 13 corresponding with retaining salient point.Only
Turn limited step 16 can play a part of limit end cap screw-in depth, it is to avoid do not screw or excessive screwing situation, meanwhile, when
When spiral cover is screwed, retaining salient point is slipped in the retaining groove of end cap, plays locking effect, prevents from transporting, sterilize or using
Surprisingly loosen in journey or open, remaining structure is identical with embodiment one.
Using method of the present utility model is, by taking the blood perfusion device of embodiment one as an example, respectively by the Shandong at perfusion device two ends
You are connected joint with Standard blood purification pipe joint, are filled by clinically conventional blood perfusion speed and treatment time
Stream, you can realize absorption morbid substance, the purpose of purification blood.
Perfusion device described in the utility model has preferable fluid-dynamic design, makes bubble be easy to discharge, and simplifies
Bleeding, is easy to operation, uniform into the velocity of blood flow in perfusion device, reduces the generation of the bad phenomenons such as blood coagulation, meanwhile,
Ensure that blood can be fully contacted in flow process with the adsorbent of filling in perfusion device, to improving adsorbent adsorption efficiency
With important function.
Claims (10)
1. a kind of blood perfusion device, including cylinder（1）, it is characterised in that：The cylinder（1）One end is arc transition closing in, receives
The center of mouth is outlet luer joint（2）, the outlet luer joint（2）Entrance be provided with output filtering device（3）, it is described defeated
Go out filter（3）Pore size filter be 20～100 μm or 100～300 μm, the outlet luer joint（2）With the first spiral cover
（4）Screw thread coordinates, the cylinder（1）The other end for open, the open inwall is provided with for installing divided-flow filtering apparatus（6）
Cannelure（5）, a divided-flow filtering apparatus（6）Located at the cannelure（5）In, and by an end cap（7）It is fixed, the end
Lid（7）Center be provided with import female Luer（9）, the divided-flow filtering apparatus（6）Center be provided with hemispherical point of a projection
Flow cone（8）, the hemispherical spreader（8）Radius be 2～5mm, the hemispherical spreader（8）Correspondence import female Luer
（9）Downstream orifice, import female Luer（9）Downstream orifice and hemispherical spreader（8）Between leave excessively stream clearance D, institute
Excessively stream clearance D is stated for 1～18mm, the import female Luer（9）With the second spiral cover（10）Screw thread coordinates.
2. blood perfusion device according to claim 1, it is characterised in that：The cylinder（1）Inner chamber be internal diameter from open
Hold the diminishing conical cavities in closing in end.
3. blood perfusion device according to claim 1, it is characterised in that：The segmental arc central angle alpha that cylinder arc transition closes up
For 30～90 °.
4. blood perfusion device according to claim 1, it is characterised in that：The divided-flow filtering apparatus（6）Including support rib
Frame（61）And filter membrane（62）, the support frame（61）With ring frame（61a）Be fixed on ring frame（61a）Bottom
Many support spokes（61b）, respectively support spoke（61b）Towards end cap（7）One side be cambered surface, the filter membrane（62）With it is each
Support spoke（61b）, ring frame（61a）It is fixedly connected, positioned at support frame（61）Bottom surface.
5. blood perfusion device according to claim 4, it is characterised in that：The divided-flow filtering apparatus（6）Also include polylith
The annular flow deflector of different-diameter（63）, these annular flow deflectors（63）Many support spokes are fixed in concentric arrays
（61b）On, positioned at hemispherical spreader（8）And ring frame（61a）Between, each annular flow deflector（63）Lean outward below
Tiltedly, with the filter membrane of bottom（62）Between angle γ be 10～60 °.
6. blood perfusion device according to claim 1, it is characterised in that：The divided-flow filtering apparatus（6）Including support rib
Frame（61）And filter membrane（62）, the support frame（61）With ring frame（61a）Be fixed on ring frame（61a）Bottom
Filter plate（61c）, the filter plate（61c）It is provided with some vias, the filter membrane（62）It is fixed on filter plate（61c）Below.
7. blood perfusion device according to claim 1, it is characterised in that：The cylinder（1）Arc transition closing in end end
Face, end cap（7）On be respectively equipped with multiple retaining salient points around female Luer（12）, first spiral cover（4）, the second spiral cover
（10）Axial end on be respectively equipped with and retaining salient point（12）The retaining groove of cooperation（13）.
8. blood perfusion device according to claim 1, it is characterised in that：The cylinder（1）Open outer wall is provided with outer
Thread segment, the end cap（7）Coordinated by screw thread and be fixed on cylinder（1）Upstream end, by divided-flow filtering apparatus（6）It is fixed
In cylinder（1）Cannelure（5）In, the end cap（7）And divided-flow filtering apparatus（6）Between be provided with O-ring seal（14）.
9. blood perfusion device according to claim 1, it is characterised in that：The end cap（7）End face be plane, or for cone
Face, the vertex of a cone angle β of the conical surface is 145～175 °.
10. blood perfusion device according to claim 1, it is characterised in that：Second spiral cover（10）, the first spiral cover（4）、
End cap（7）Circumference side on be respectively equipped with anti-skidding convex tendon（15）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620938610.0U CN206151974U (en) | 2016-08-25 | 2016-08-25 | Hemoperfusion apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620938610.0U CN206151974U (en) | 2016-08-25 | 2016-08-25 | Hemoperfusion apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206151974U true CN206151974U (en) | 2017-05-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620938610.0U Withdrawn - After Issue CN206151974U (en) | 2016-08-25 | 2016-08-25 | Hemoperfusion apparatus |
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| Country | Link |
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| CN (1) | CN206151974U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106110427A (en) * | 2016-08-25 | 2016-11-16 | 重庆郑博生物科技有限公司 | blood perfusion device |
| CN113075028A (en) * | 2021-04-30 | 2021-07-06 | 海宁凯兴新材料股份有限公司 | Wear resistance detection equipment for warp knitting cloth |
-
2016
- 2016-08-25 CN CN201620938610.0U patent/CN206151974U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106110427A (en) * | 2016-08-25 | 2016-11-16 | 重庆郑博生物科技有限公司 | blood perfusion device |
| CN113075028A (en) * | 2021-04-30 | 2021-07-06 | 海宁凯兴新材料股份有限公司 | Wear resistance detection equipment for warp knitting cloth |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20170510 Effective date of abandoning: 20180907 |
|
| AV01 | Patent right actively abandoned |