CN205749234U - Multifunctional bio in vitro soft tissue parameter measurement platform - Google Patents

Abstract

This utility model provides a kind of multifunctional bio in vitro soft tissue parameter measurement platform, is mainly made up of experiment assistance platform and experiment measuring table.This utility model can carry out four kinds of different experiments to soft tissue: uniaxial compression tests (pressure head is slowly depressed into certain position)；Stress relaxation experiment (pressure head depressed fast keeps a period of time to certain position)；Creep test (wire rope suspensioning counterweight)；Soft tissue punctures experiment.Mechanism uses screw thread pair to drive the mode of wire rope gearing to realize the small strain of soft tissue sample.This utility model efficiently solves and is only capable of in teeth uncovered by lips relying on material experiment-machine and measuring the problem that parameter is single, has certain promotional value.

Description

Multifunctional biological isolated soft tissue parameter measurement platform

technical field

The utility model relates to a measuring platform, in particular to a multifunctional biological isolated soft tissue parameter measuring platform.

Background technique

Virtual surgery is a very important research content in the field of minimally invasive surgery, and it is difficult to establish an accurate physical model including biological soft tissue parameters. At present, the measurement of soft tissue parameters relies on professional material testing machines, and is limited to the measurement of physical characteristic parameters of some tissues. Compared with the traditional method of using a professional material testing machine to measure parameters, the utility model patent provides a simple and effective multi-parameter measurement platform of biological soft tissue, which has a measurement platform and an auxiliary platform. The overall structure of the mechanism is simple, and the transmission is realized by the pulley block and the wire rope. It is easy to control, and the experimental tools (indenter and puncture needle) can be replaced at the end. It can mainly carry out four different biological experiments, and finally obtain multiple parameters of the soft tissue through the experiments.

Contents of the invention

The purpose of the utility model is to provide a multifunctional biological soft tissue parameter measurement platform with simple structure and easy control.

The purpose of this utility model is achieved in that it includes an auxiliary platform and a measuring platform, the auxiliary platform includes a base, a column installed on the base, a bracket A installed on the column, a bracket B and an adjustable mounting bracket , the bracket A and bracket B are on one end face of the pillar and the bracket A is above the bracket B, the end face where the adjustable position mounting bracket is located is adjacent to the end face where the bracket A is located, and the bracket A is installed with a tensioning wheel and pre-tightening wheel, the lower end surface of the bracket B is provided with a first wheel and a second wheel, and a third wheel is arranged on the installation bracket of the adjustable position; the measuring platform includes a vertically installed The slide rail on the installation bracket with adjustable position, the slide block installed in the slide rail, the connecting piece B fixedly connected with the slide block, the connecting piece A fixedly connected with the upper end of the connecting piece B, the puller arranged at the lower end of the connecting piece B The pressure sensor and the linear displacement potentiometer installed between the adjustable position mounting bracket and the connecting piece A, the end of the adjustable position mounting bracket is provided with a chute, the connecting piece B is located in the chute, and the connecting piece There is also a tension spring between A and the bracket B, and a steel wire rope is arranged on the tension wheel, and the end of the steel rope goes around the pretension wheel, the first pulley, the second pulley, and the third pulley in sequence and connects with the The component A is fixedly connected, and the lower end of the tension pressure sensor is provided with a pressure head or a needle, and the pressure head or needle is located above the glass dish arranged on the base.

The utility model also includes such structural features:

1. There are rulers on the connecting piece B and the column respectively.

Compared with the prior art, the beneficial effects of the utility model are: the utility model is a single-platform, multi-purpose experimental device, compared with a professional material testing machine, it has a compact structure and takes up less space; the utility model has a simple structure , using the pulley block and wire rope to realize the transmission, and realizing the low-speed movement of the measuring tool in the vertical direction through the thread pair, the whole experimental process is easy to control. The positions of multiple components of the auxiliary platform of the utility model can be adjusted, and a larger range of travel can be realized through adjustment; each part of the utility model is connected by screws, which is easy to assemble and disassemble, and is convenient for maintenance; the utility model can be quickly replaced at the end of the sensor. The tool can carry out different experiments to realize the measurement of different parameters, and has versatility.

Description of drawings

Fig. 1 is the overall structural representation of the utility model;

Fig. 2 is the schematic diagram of the experimental auxiliary platform of the present utility model;

Fig. 3 is a schematic diagram of the tensioning wheel of the present utility model;

Fig. 4 is a schematic diagram of passing the wheel of the present utility model;

Fig. 5 is a schematic diagram of the pretensioner wheel of the present utility model;

Fig. 6 is a schematic diagram of the experimental measurement platform of the present invention.

detailed description

Below in conjunction with accompanying drawing and specific embodiment the utility model is described in further detail.

With reference to FIG. 1 , the utility model is mainly composed of an experimental auxiliary platform 1 and an experimental measurement platform 2 . The experimental auxiliary platform 1 is used to realize the transmission of the mechanism, and the experimental measurement platform 2 is used to obtain the force-position data of the soft tissue samples during the experiment in real time.

Combined with Figure 2, the experimental auxiliary platform 1 is composed of bracket A1-1, tension wheel 1-2, hexagon socket screw 1-3, scale 1-4, column 1-5, bracket B1-6, tension spring bracket A1-7, Steel wire rope 1-8, three rollers 1-9, mounting bracket 1-10, pretensioner wheel 1-11, base 1-12, glass dish 1-13 are formed. Extension spring support A1-7 is made up of shaft end retaining ring 1-7-1, support 1-7-2, bearing pin 1-7-3. The column 1-5 is fixed on the base 1-12 by screws. The bracket A1-1, the bracket B1-6, and the mounting bracket 1-10 are connected to the column 1-5 by screws. The tensioning wheel 1-2 and the pretensioning wheel 1-11 are fixed on the bracket A1-1 by screws. During the experiment, a certain amount of physiological saline was stored in the glass dishes 1-13 to ensure the cell viability of the soft tissue samples. Before the experiment, the stroke of the measurement platform can be adjusted by adjusting the position of the scale line of the mounting bracket 1-10 on the scale 1-4. Adjust the pretensioner 1-11 so that the steel wire rope 1-8 has a certain initial tension, so that the steel wire rope 1-8 is in a tensioned state to ensure that the movement of the measuring platform is stable during the experiment. The steel wire rope 1-8 has two functions: first, the end of the steel wire rope 1-8 is wound on the tensioning wheel. In the experiment, the thread transmission is realized by adjusting the tensioning wheel 1-2 to pull the steel wire rope 1-8 to realize the vertical downward movement of the measuring platform. Displacement operation, under this condition, uniaxial compression and stress relaxation experiments can be performed on soft tissue; second, weights are hung at the end of the steel wire rope 1-8, so that a constant load can be applied to soft tissue, and creep experiment can be performed under this condition.

Combined with Figure 3, the tensioning wheel 1-2 consists of hexagon socket head cap screw 1-2-1, tensioning wheel slider 1-2-2, tensioning wheel bracket 1-2-3, miniature bearing bushing 1-2-4 , nut 1-2-5, pulley 1-2-6, hexagon socket head screw 1-2-7. The tensioning wheel bracket 1-2-3 is installed on the bracket A1-1 through screws, the hexagon socket head screw 1-2-1 and the tensioning wheel bracket 1-2-3 are connected by a thread pair, and the tensioning wheel bracket 1- 2-3 is provided with a slideway, the tensioner slider 1-2-2 is installed in the slideway, and the end of the hexagon socket screw 1-2-1 is connected with the tensioner slider 1-2-2, The pulley 1-2-6 is installed on the end of the tensioner slider 1-2-2 through the inner hexagon screw 1-2-7, and the tensioner slider 1-2-2 can be realized by turning the inner hexagon screw 1-2-1. 2-2 slide horizontally on the slide.

In conjunction with Figure 4, the passing wheel 1-9 consists of a nut 1-9-1, a spring washer 1-9-2, a pulley 1-9-3, a support base 1-9-4, and a miniature bearing bushing 1-9-5 , Hexagonal screws 1-9-6. The main function of the wheel is to change the direction of the wire rope.

Combined with Figure 5, the pretension wheel 1-11 is composed of hexagon socket screw M21-11-1, pretension wheel bracket 1-11-2, pretension wheel slider 1-11-3, hexagon socket screw M31-11-4, Miniature bearing axle sleeve 1-11-5, pulley 1-11-6, nut 1-11-7 form. The pre-tension wheel and the tension wheel are implemented in the same way, both realize the movement of the slider in the support slideway through thread transmission, and the pre-tension wheel is mainly used for tensioning the steel wire rope before the experiment.

Combined with Figure 6, the experimental measurement platform 2 consists of a linear slide rail 2-1, a limit stopper 2-2, a linear displacement potentiometer 2-3, a slider 2-4, a rope connection cap 2-5, and a sensor connector 2 -6, extension spring 2-7, extension spring bracket B2-8, connection piece A2-9, connection piece B2-10, hexagon socket head screw 2-11, scale 2-12, nut 2-13, tension pressure sensor 2- 14. The pressure head 2-15 is formed, wherein the extension spring support B2-8 is composed of the shaft end retaining ring 2-8-1, the support 2-8-2, and the bearing pin 2-8-3. The two linear slide rails 2-1 and the linear displacement potentiometer 2-3 are fixed on the mounting bracket 1-10 of the auxiliary platform by screws, and the linear displacement potentiometer 2-3 records the displacement of the measurement platform during the experiment. Connecting piece A2-9 and connecting piece B2-10 are fixedly connected by screws. The slider 2-4 is fixedly connected with the connecting piece B2-10 by screws. There is a slide block 2-4 on each linear slide rail 2-1, so that the movement is more stable, and the smooth compression deformation of the soft tissue is realized through the combination of the two. The tension and pressure sensor 2-14 is connected to the connector B2-10 through threads and fixed by the nut 2-13. The tension and pressure sensor 2-14 records the deformation force of the soft tissue during the experiment. When the force is greater than the set threshold Soft tissue contact is considered to occur. The extension spring bracket B2-8 and the rope connection cap 2-5 are fixed on the connecting piece A2-9 by the same screw, and the extension spring 2-7 provides upward pulling force for the experimental measurement platform to avoid sliding downward under the influence of its own gravity. Scale 2-12 is convenient for estimating the strain of the soft tissue during the experiment and preventing excessive compression from damaging the soft tissue sample. Limit block 2-2 plays the effect of mechanical limit. The shaft end retaining ring 2-8-1 of the extension spring support B2-8 is used for the axial positioning of the pin shaft 2-8-3.

Two different measurement tools can be installed at the end of the pull pressure sensor 2-14. First, an indenter 2-15 is installed at the end for uniaxial compression, stress relaxation experiment and creep experiment. Uniaxial compression test process: the end of the test wire rope 1-8 is wound on the pulley 1-2-6 of the tension pulley 1-2. Put the cut soft tissue sample into the middle position of the glass dish 1-13 containing physiological saline, and pre-adjust the position of the indenter 2-15 before the experiment, that is, adjust the scale line of the mounting bracket 1-10 on the scale 1-4 The proper position of the indenter makes the downward displacement of the indenter not exceed 40% of the thickness of the tissue sample, preventing the tissue from being crushed. Slowly turn the tensioning wheel screw 1-2-1, drive the tensioning wheel slider 1-2-2 to slide in the slideway of the tensioning wheel bracket 1-2-3 through thread transmission, and pull the wire rope 1-8 down for experimental measurement Platform 2, when the force data collected by the pull pressure sensor 2-14 is greater than the set value, the pressure head 2-15 contacts the soft tissue sample, and starts to record the displacement data of the linear displacement potentiometer 2-3, when the limit stopper 2 When -2 moves to contact with the installation bracket 1-10, stop the movement. Then reversely rotate the tensioning wheel screw 1-2-1, and now the experimental measurement platform 2 will rise slowly under the tension of the extension spring 2-7, return to the original position, and the experiment ends. Stress relaxation test process: Same as the uniaxial test, the position of the indenter 2-15 is pre-adjusted. Quickly turn the tensioning wheel screw 1-2-1, so that the limit stopper 2-2 moves to the contact position with the installation bracket 1-10 as soon as possible, and keep the position of the pressure head at this time for about 20 to 30 minutes. With the extension of time, The deformation force of the soft tissue will become smaller and tend to be stable, and the data of the two sensors will be collected during the collection. Creep test process: During this test, a weight of a certain mass is hung at the end of the steel wire rope 1-8, the lower end of the tension spring 2-7 is separated from the tension spring bracket B2-8, and the scale line of the installation bracket 1-10 is adjusted on the scale 1-10. 4's bottom position. The steel wire ropes 1-8 will pull the experimental measurement platform 2 to move downward under the action of the gravity of the weight, and cause tissue deformation after contacting with the soft tissue. The amount of deformation will gradually increase with the increase of time, and the data of the two sensors during the experiment are recorded. Second, a puncture needle is installed at the end for puncture experiments. Puncture test process: The puncture test is similar to the uniaxial compression test, first adjust the scale line 1-10 of the mounting bracket to the appropriate position of the scale 1-4. Slowly turn the tensioning wheel screw 1-2-1, the puncture needle will contact with the soft tissue, puncture and insert. Record data from both sensors during the experiment. On the basis of the physical model of soft tissue, with the help of the above experimental data, multiple parameters of the physical model can be obtained through software fitting.

The connection between the experimental auxiliary platform 1 and the experimental measurement platform 2 is mainly fixed by bypassing the tensioning wheel 1-2 at one end, and the other end is connected by a rope after being driven by the pretensioning wheel 1-11 and three passing wheels 1-9 and changing the direction. The cap 2-5 is connected by a steel wire rope 1-8 fixed on the connector A2-9 by screws; it is connected by an extension spring 2-7 whose one end is fixed on the extension spring support A1-7 and the other end is fixed on the extension spring support B2-8; The two linear slide rails 2-1 fixed on the mounting bracket 1-10 by screws are relatively slidingly connected to the two pairs of sliders 2-4 fixed on the connecting piece B2-10 by screws. The variable range of stroke of the measurement platform is reflected in the large adjustable range of the scale line of the mounting bracket 1-10 on the scale 1-4. Therefore, the structure of the experimental platform is simple and compact, and can achieve a large range of measurement stroke.

The multi-parameter measurement platform of biological isolated soft tissue realizes the experimental purpose mainly by making the wire rope 1-8 move relative to the pulleys 1-2-6, 1-9-3, 1-11-6 so as to change the pressure head 2-15 relative to the soft tissue. distance. Tensioning wheel 1-2 consists of hexagon socket head screw 1-2-1, tensioning wheel slider 1-2-2, tensioning wheel bracket 1-2-3, miniature bearing bushing 1-2-4, nut 1- 2-5, pulley 1-2-6 form. Pretensioner 1-11 consists of hexagon socket screw M21-11-1, pretensioner bracket 1-11-2, pretensioner slider 1-11-3, hexagon socket screw M31-11-4, miniature bearing sleeve 1-11-5, pulley 1-11-6, nut 1-11-7 form. The inner hexagonal screw 1-2-1 and the tensioner bracket 1-2-3 are connected by a thread pair, and the inner hexagonal screw 1-2-1 can be turned to realize the tensioner slider 1-2-2 on the slideway Slide horizontally, thereby adjust the position of wire rope 1-8 relative to pulley 1-2-6, 1-9-3, 1-11-6. The realization way of the pretensioner and the tensioner is the same, and both realize horizontal movement through thread transmission. Adjust the pretensioner 1-11 so that the steel wire rope 1-8 has a certain initial tension, so that it is in a tensioned state to ensure the stability of the measurement platform movement during the experiment. By adjusting the tensioner 1-2 to achieve thread transmission and pull the wire rope to achieve Measure the vertical downward micro-displacement operation of the platform. During the experiment, the extension springs 2-7 provide an upward pulling force for the experimental measurement platform to avoid sliding downward under the influence of its own gravity. Scale 2-12 is convenient for estimating the strain of the soft tissue during the experiment and preventing excessive compression from damaging the soft tissue sample. The biological isolated soft tissue multi-parameter measurement platform adopts thread transmission to pull the steel wire rope to realize micro-displacement adjustment, effectively avoiding the shaking of human hands; the design of tension spring and limit block achieves the purpose of easy and stable control of the experiment, reflecting the scientific nature of the experimental platform .

Adjust the pretensioner 1-11 to make the wire rope 1-8 have a certain initial tension, and make the wire rope 1-8 in a tensioned state to ensure that the movement of the measurement platform is stable during the experiment. By adjusting the tensioner 1-2, the thread The transmission pulls the wire rope to realize the vertical downward micro-displacement operation of the measuring platform. Under this condition, uniaxial compression experiments and stress relaxation experiments can be carried out. The end of steel wire rope 1-8 also can hang weight to realize the loading of certain constant load, can carry out creep test under this condition. The indenter 2-15 can be replaced with a puncture needle for puncture experiments. Therefore, the utility model is a single-platform, multi-purpose experimental device, which can carry out different experiments to realize the measurement of different parameters, and has multi-functionality.

The utility model relates to a measurement platform for the physical characteristic parameters of isolated biological soft tissues. An experimental mechanism capable of measuring various parameters of soft tissues is specially designed, which can realize the measurement of stress-strain characteristic parameters, creep characteristic parameters and relaxation characteristic parameters of biological soft tissues. And the measurement of puncture characteristic parameters is mainly composed of an experimental auxiliary platform 1 and an experimental measurement platform 2; the experimental measurement platform is composed of a force sensor, a displacement sensor, a connecting shaft, a mounting bracket, a linear module, a tension spring, and a spring connecting frame. The experimental auxiliary platform is composed of a column, a base, a glass dish, a pulley block, an adjustment bracket, and a wire rope. The utility model can carry out four different experiments on soft tissue: uniaxial compression experiment (indenter is slowly pressed down to a certain position); stress relaxation experiment (indenter is quickly pressed down to a certain position and kept for a period of time); creep experiment (wire rope Suspension weight); soft tissue puncture test. This mechanism adopts the thread pair to drive the steel wire rope to realize the small strain of the soft tissue sample. The utility model effectively solves the problems of only relying on a material testing machine and a single measurement parameter in soft tissue measurement, and has certain popularization value.

Claims (2)

1. The multifunctional biological isolated soft tissue parameter measurement platform is characterized in that: it includes an auxiliary platform and a measurement platform, and the auxiliary platform includes a base, a column installed on the base, a support A, a support B and a support installed on the support. An adjustable position mounting bracket, the bracket A and bracket B are on one end face of the pillar and the bracket A is located above the bracket B, the end face of the adjustable position mounting bracket is adjacent to the end face where the bracket A is located, and the bracket A tensioning wheel and a pre-tensioning wheel are installed on A, the lower end surface of the bracket B is provided with a first passing wheel and a second passing wheel, and the third passing wheel is arranged on the installation bracket of the adjustable position; the measuring The platform includes a slide rail vertically installed on a mounting bracket at an adjustable position, a slide block installed in the slide rail, a connecting piece B fixedly connected with the slide block, a connecting piece A fixedly connected with the upper end of the connecting piece B, and a The tension and pressure sensor at the lower end of the connecting piece B and the linear displacement potentiometer installed between the adjustable position mounting bracket and the connecting piece A, the end of the adjustable position mounting bracket is provided with a slide groove, and the connecting piece B is located on the slide In the groove, a tension spring is also arranged between the connector A and the bracket B, and a wire rope is arranged on the tension wheel, and the end of the wire rope goes around the pretension wheel, the first pulley, the second pulley, and the second pulley in turn. After three rounds, it is fixedly connected with the connecting piece A, and the lower end of the tension pressure sensor is provided with a pressure head or a needle, and the pressure head or needle is located above the glass vessel arranged on the base. 2. The multifunctional biological isolated soft tissue parameter measurement platform according to claim 1, characterized in that: the connecting piece B and the column are respectively provided with scales.