CN205333633U - Dull and stereotyped agglutinate reaction unit of serum - Google Patents
Dull and stereotyped agglutinate reaction unit of serum Download PDFInfo
- Publication number
- CN205333633U CN205333633U CN201521029766.9U CN201521029766U CN205333633U CN 205333633 U CN205333633 U CN 205333633U CN 201521029766 U CN201521029766 U CN 201521029766U CN 205333633 U CN205333633 U CN 205333633U
- Authority
- CN
- China
- Prior art keywords
- flat board
- spherical reflector
- serum
- plate
- agglutination reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000002966 serum Anatomy 0.000 title claims abstract description 18
- 238000006243 chemical reaction Methods 0.000 title abstract description 25
- 230000004520 agglutination Effects 0.000 claims abstract description 36
- 239000011521 glass Substances 0.000 claims description 6
- 229920003023 plastic Polymers 0.000 claims description 6
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 4
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 4
- 239000011347 resin Substances 0.000 claims 2
- 229920005989 resin Polymers 0.000 claims 2
- 238000012360 testing method Methods 0.000 abstract description 6
- 238000009792 diffusion process Methods 0.000 abstract description 5
- 230000003760 hair shine Effects 0.000 abstract description 2
- 230000007613 environmental effect Effects 0.000 abstract 1
- 239000011324 bead Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 6
- 239000007788 liquid Substances 0.000 description 5
- 239000000427 antigen Substances 0.000 description 4
- 102000036639 antigens Human genes 0.000 description 4
- 108091007433 antigens Proteins 0.000 description 4
- 239000012295 chemical reaction liquid Substances 0.000 description 3
- 239000004417 polycarbonate Substances 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 1
- 229920005372 Plexiglas® Polymers 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000000075 oxide glass Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229910052814 silicon oxide Inorganic materials 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
Landscapes
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
血清平板凝集反应装置，涉及一种医疗化验用具，解决了现有凝集反应平板在实验过程中相邻样品液珠易扩散而连通影响结果判定，大量样品试验易出现结果与样品对应混乱和凝集反应结果判定易受环境光线变化影响等问题。该装置包括底座；安装在底座内部的球面反射镜，所述球面反射镜镜面向上；安装在球面反射镜底部中心的白炽灯，通过球面反射镜的反射作用使白炽灯发出的光线向正上方出射；放置在白炽灯光源底座上方的网格标号平板，所述白炽灯发出的光线照射在网格标号平板下表面。本实用新型结构简单、操作方便、可使凝集反应液滴形成稳定的液珠，且液珠扩散小，通过白光照射可辅助观察平板凝集反应结果，不但不易出现失误，并且易于准确判读结果。
The serum plate agglutination reaction device relates to a medical laboratory appliance, which solves the problem that in the existing agglutination reaction plate, adjacent sample droplets are easy to diffuse and connected to affect the result judgment, and a large number of sample tests are prone to result and sample correspondence confusion and agglutination reaction As a result, it is determined that it is susceptible to environmental light changes and other issues. The device includes a base; a spherical reflector installed inside the base, and the mirror surface of the spherical reflector is upward; an incandescent lamp installed at the center of the bottom of the spherical reflector, through the reflection of the spherical reflector, the light emitted by the incandescent lamp is emitted directly upward ; Place the grid marking plate above the base of the incandescent light source, and the light emitted by the incandescent lamp shines on the lower surface of the grid marking plate. The utility model has the advantages of simple structure and convenient operation, which can make the agglutination reaction droplets form stable droplets, and the droplets have small diffusion. The utility model can assist in observing the plate agglutination reaction results through white light irradiation, and is not only difficult to make mistakes, but also easy to accurately interpret the results.
Description
技术领域technical field
本实用新型涉及一种医疗化验用具，具体涉及一种血清平板凝集反应装置。The utility model relates to a medical laboratory appliance, in particular to a serum plate agglutination reaction device.
背景技术Background technique
血清凝集反应指颗粒性抗原例如细菌、红细胞等与相应的抗体在适量的电解质存在的条件下，经一定时间后凝聚成肉眼可见的凝集物。凝集反应广泛地应用于疾病的诊断和各种抗原性质的分析。血清凝集反应试验方法中最为简便快速的是玻片法。玻片法是一种定性试验方法，可用已知抗体来检测未知抗原。在鉴定新分离的菌种时，可取已知抗体滴加在玻片上，将待检菌液一滴与其混匀，如出现肉眼可见的凝集现象，为阳性反应。该法简便快速，除鉴定菌种外，尚可用于菌种分型、测定人类红细胞的ABO血型等。抗原或试剂与血清的凝集反应检测通常在无色透明氧化硅玻璃平板上进行，液珠在混匀过程易扩散，相邻样品液珠由于扩散而连通影响结果判定；大量样品试验易出现加样和结果判读混乱，而且凝集反应结果判定易受环境光线变化影响结果判定。Serum agglutination refers to the agglutination of particulate antigens such as bacteria, red blood cells, etc., and corresponding antibodies in the presence of an appropriate amount of electrolytes after a certain period of time to form agglutinations that are visible to the naked eye. Agglutination is widely used in the diagnosis of diseases and the analysis of the properties of various antigens. The easiest and fastest method of serum agglutination test is the slide method. The slide method is a qualitative test method in which known antibodies can be used to detect unknown antigens. When identifying newly isolated strains, it is advisable to drop a known antibody on a glass slide, mix a drop of the bacteria solution to be tested with it, and if there is agglutination visible to the naked eye, it is a positive reaction. The method is simple and fast, and can be used for strain typing, determination of ABO blood type of human red blood cells, etc. in addition to identification of strains. The detection of agglutination reaction between antigen or reagent and serum is usually carried out on a colorless transparent silica glass plate. The liquid beads are easy to diffuse during the mixing process, and the adjacent sample liquid beads are connected due to diffusion, which affects the result judgment; a large number of sample tests are prone to sample addition And the interpretation of the results is confusing, and the judgment of the agglutination reaction is easily affected by the change of ambient light.
实用新型内容Utility model content
为了解决现有凝集反应板在实验过程中相邻样品液珠易扩散而连通影响结果判定的问题，本实用新型提供一种可使凝集反应液滴形成稳定的液珠，且液珠扩散小，通过白光照射可辅助观察凝集反应结果的血清平板凝集反应装置。In order to solve the problem that in the existing agglutination reaction plate, the adjacent sample droplets are easy to spread and the connection affects the judgment of the result, the utility model provides a stable droplet that can make the agglutination reaction droplet form, and the droplet diffusion is small, A serum plate agglutination reaction device that can assist in observing the agglutination reaction result by white light irradiation.
本实用新型为解决技术问题所采用的技术方案如下：The technical scheme that the utility model adopts for solving technical problems is as follows:
本实用新型的血清平板凝集反应装置，包括：The serum plate agglutination reaction device of the present utility model comprises:
白炽灯光源底座；Incandescent light source base;
安装在白炽灯光源底座内部的球面反射镜，所述球面反射镜镜面向上；A spherical reflector installed inside the base of the incandescent light source, the mirror surface of the spherical reflector is upward;
安装在球面反射镜底部中心的白炽灯，通过球面反射镜的反射作用使白炽灯发出的光线向正上方出射；The incandescent lamp installed at the bottom center of the spherical reflector makes the light emitted by the incandescent lamp go straight up through the reflection of the spherical reflector;
放置在白炽灯光源底座上方的网格标号平板，所述白炽灯发出的光线照射在网格标号平板下表面。The grid marking plate placed above the base of the incandescent light source, the light emitted by the incandescent lamp irradiates the lower surface of the grid marking plate.
进一步的，所述网格标号平板采用无色透明有机玻璃或无色透明塑料板制成。Further, the grid marking plate is made of colorless transparent organic glass or colorless transparent plastic plate.
进一步的，所述无色透明有机玻璃为聚甲基丙烯酸甲酯。Further, the colorless transparent organic glass is polymethyl methacrylate.
进一步的，所述无色透明塑料板为聚碳酸酯。Further, the colorless transparent plastic plate is polycarbonate.
进一步的，所述网格标号平板厚度为1～2mm。Further, the thickness of the grid marking plate is 1-2mm.
进一步的，所述网格标号平板上表面印有多个由黑色网格线组成的正方形网格，每个正方形网格的面积为1cm2，在网格标号平板上表面边缘对每个正方形网格进行数字编号。Further, the upper surface of the grid marking plate is printed with a plurality of square grids composed of black grid lines, each square grid has an area of 1 cm 2 , and the edge of the grid marking plate is opposite to each square grid. The cells are numbered.
本实用新型的有益效果是：本实用新型针对现有凝集反应板在实验过程中相邻样品液珠易扩散而连通影响结果判定的问题，设计出一种可使凝集反应液滴形成稳定的液珠，且液珠扩散小，通过白光照射可辅助观察凝集反应结果的用于血清凝集反应的网格标号平板及其观察光源，其优势在于：The beneficial effects of the utility model are: the utility model aims at the problem that the adjacent sample liquid droplets in the existing agglutination reaction plate are easy to diffuse and the connection affects the judgment of the result, and a solution that can make the agglutination reaction droplets form stable is designed. Beads, and the diffusion of liquid beads is small, and the grid label plate and its observation light source for serum agglutination reaction that can assist in observing the result of agglutination reaction through white light irradiation have the following advantages:
1、本实用新型中的网格标号平板材质选择无色透明有机玻璃或塑料板，厚度1～2mm，与现有的氧化硅玻璃平板比较，选用的材质可使滴加的反应液形成稳定的液珠，且液珠在混匀时扩散小；1. The grid label plate material in the utility model is colorless transparent plexiglass or plastic plate with a thickness of 1-2mm. Compared with the existing silicon oxide glass plate, the selected material can make the dripping reaction solution form a stable Liquid beads, and the droplets spread little when mixing;
2、用球面反射镜反射平行白炽灯光源，从网格标号平板下表面照射反应液珠，方便判读凝集反应，不受环境光线变化限制；2. Use a spherical reflector to reflect the parallel incandescent light source, and irradiate the reaction liquid beads from the lower surface of the grid label plate, which is convenient for interpreting the agglutination reaction, and is not limited by the change of ambient light;
3、网格标号平板为每个面积为1cm2正方形网格中仅加入一个样品，因此易于快速准确识别每个样品所在的编号，避免大量样品测试加样、结果判读时的混乱。平板尺寸可根据载样数量需要确定，这种网格标号设计适用检测大量样品。 3. The grid label plate only adds one sample to each square grid with an area of 1cm2, so it is easy to quickly and accurately identify the number of each sample, and avoid confusion when adding a large number of samples to the test and interpreting the results. The size of the plate can be determined according to the number of samples loaded, and this grid label design is suitable for testing a large number of samples.
附图说明Description of drawings
图1为本实用新型的血清平板凝集反应装置的结构示意图；Fig. 1 is the structural representation of the serum plate agglutination reaction device of the present utility model;
图2为血清碘凝集试验在网格标号平板上的效果图。Fig. 2 is an effect diagram of a serum iodine agglutination test on a grid-marked flat plate.
图中：1、网格标号平板，2、白炽灯，3、球面反射镜，4、白炽灯光源底座。In the figure: 1, the grid label plate, 2, the incandescent lamp, 3, the spherical reflector, 4, the base of the incandescent light source.
具体实施方式detailed description
以下结合附图对本实用新型作进一步详细说明。Below in conjunction with accompanying drawing, the utility model is described in further detail.
如图1所示，本实用新型的血清平板凝集反应装置，主要由网格标号平板1、白炽灯2、球面反射镜3和白炽灯光源底座4组成。As shown in FIG. 1 , the serum plate agglutination reaction device of the present invention is mainly composed of a grid label plate 1 , an incandescent lamp 2 , a spherical reflector 3 and an incandescent light source base 4 .
白炽灯光源底座4放置在最下方，白炽灯光源底座4内部安装有球面反射镜3，球面反射镜3镜面向上。The base 4 of the incandescent light source is placed at the bottom, and a spherical reflector 3 is installed inside the base 4 of the incandescent light source, and the mirror surface of the spherical reflector 3 is upward.
在白炽灯光源底座4上方放置网格标号平板1，网格标号平板1上表面印有多个由黑色网格线组成的正方形网格，每个正方形网格的面积为1cm2，在网格标号平板1上表面边缘对每个正方形网格进行数字编号，如图2所示。Place a grid label plate 1 above the incandescent light source base 4. A plurality of square grids composed of black grid lines are printed on the upper surface of the grid label plate 1. The area of each square grid is 1cm 2 . Label the edge of the upper surface of the plate 1 to number each square grid, as shown in FIG. 2 .
球面反射镜3底部中心安装有白炽灯2，通过球面反射镜3的反射作用使白炽灯2发出的光线向正上方反射，白炽灯2发出的光线照射在网格标号平板1下表面。Spherical reflector 3 bottom center is equipped with incandescent lamp 2, the light that incandescent lamp 2 sends is reflected directly upwards by the reflection of spherical reflector 3, and the light that incandescent lamp 2 sends shines on grid label plate 1 lower surface.
网格标号平板1材质选择无色透明有机玻璃(聚甲基丙烯酸甲酯PMMA)或无色透明塑料板(聚碳酸酯PC)，厚度为1～2mm。Grid marking plate 1 is made of colorless transparent organic glass (polymethyl methacrylate PMMA) or colorless transparent plastic plate (polycarbonate PC), with a thickness of 1-2 mm.
使用时，将样品反应液珠按照编号依次滴加在网格标号平板1上表面的黑色正方形网格内(面积在1cm2)，点亮白炽灯2，通过白光照射侧视观察凝集反应过程、结果即可。When in use, drop the sample reaction liquid beads in sequence according to the number in the black square grid (with an area of 1 cm 2 ) on the upper surface of the grid label plate 1, light up the incandescent lamp 2, and observe the agglutination reaction process by side-viewing through white light irradiation, The result will do.
本实用新型结构简单、操作方便、凝集反应液珠扩散小，通过白光照射可辅助观察平板凝集反应结果，不但不易出现失误，并且易于准确判读结果。The utility model has the advantages of simple structure, convenient operation, and small diffusion of agglutination reaction liquid beads, and can assist in observing plate agglutination reaction results through white light irradiation, which is not only difficult to make mistakes, but also easy to accurately interpret the results.
Claims (6)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521029766.9U CN205333633U (en) | 2015-12-14 | 2015-12-14 | Dull and stereotyped agglutinate reaction unit of serum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521029766.9U CN205333633U (en) | 2015-12-14 | 2015-12-14 | Dull and stereotyped agglutinate reaction unit of serum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205333633U true CN205333633U (en) | 2016-06-22 |
Family
ID=56212731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201521029766.9U Expired - Fee Related CN205333633U (en) | 2015-12-14 | 2015-12-14 | Dull and stereotyped agglutinate reaction unit of serum |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205333633U (en) |
-
2015
- 2015-12-14 CN CN201521029766.9U patent/CN205333633U/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103323605B (en) | A kind of micro-fluidic chip of saccharification hemoglobin immune detection | |
| CN103063856B (en) | Full-automatic fecal occult blood analyzer | |
| CN102147409B (en) | A kind of method measuring Anti-nucleosome antibodies IgG and reagent device | |
| CN103439518B (en) | A kind of blood ABD shapes rapid integrated test card | |
| CN106622416B (en) | A kind of detection hs-CRP micro-fluidic paper chip and preparation method thereof and kit | |
| CN111638373A (en) | Kit for ABO blood group positive typing and Rh blood group detection and preparation method and detection method thereof | |
| CN203231968U (en) | Fiber-optic small-volume gold-labeled immunochromatographic test paper detector | |
| Ashiba et al. | Hemagglutination detection for blood typing based on waveguide-mode sensors | |
| CN106290328A (en) | For the slide of liquid calcium ion detection or reagent paper array and preparation and application | |
| JP2022520050A (en) | Assay with reduced interference (III) | |
| CN205333633U (en) | Dull and stereotyped agglutinate reaction unit of serum | |
| CN208156013U (en) | Exosome-based cancer detection system | |
| CN202562928U (en) | Visualized protein chip device | |
| TWM502845U (en) | Reagent cartridge slot structure | |
| CN201926651U (en) | Sulfur dioxide detection reagent kit | |
| CN105486625A (en) | Cell counting device and method based on Terahertz time-domain spectroscopy technology | |
| CN204269656U (en) | A kind of test macro and immuno-chromatographic test paper strip thereof | |
| RU2014115399A (en) | MULTIPARAMETRIC DIAGNOSTIC TEST SYSTEM FOR THE DETECTION AND MONITORING OF THERAPY OF BREAST CANCER AND OVARIAN CANCER, AND METHOD FOR ANALYSIS WITH ITS USE | |
| CN103837686A (en) | Kit for detecting human immunoglobulin G4 as well as preparation method of kit | |
| CN203310752U (en) | Aflatoxin quantitative detector | |
| CN206470189U (en) | A kind of multichannel heart infarction mark analyzer towards real-time test | |
| CN106769907A (en) | Quantitative analysis instrument | |
| CN204314299U (en) | A kind of fluorescence immunoassay quantitative test reagent card | |
| CN105326511B (en) | A kind of vacuum blood sampler for immune detection | |
| CN104483480A (en) | Low-noise excitation type fluorescent marker based immunochromatography test strip for vibrio parahaemolyticus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160622 Termination date: 20191214 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |