CN205027758U - Carbon quantum dot test strip - Google Patents
Carbon quantum dot test strip Download PDFInfo
- Publication number
- CN205027758U CN205027758U CN201520693313.XU CN201520693313U CN205027758U CN 205027758 U CN205027758 U CN 205027758U CN 201520693313 U CN201520693313 U CN 201520693313U CN 205027758 U CN205027758 U CN 205027758U
- Authority
- CN
- China
- Prior art keywords
- quantum dot
- carbon quantum
- pad
- nitrocellulose filter
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 title claims abstract description 42
- 238000012360 testing method Methods 0.000 title claims abstract description 15
- 229920001220 nitrocellulos Polymers 0.000 claims abstract description 25
- 239000000020 Nitrocellulose Substances 0.000 claims abstract description 24
- 239000000427 antigen Substances 0.000 claims abstract description 17
- 102000036639 antigens Human genes 0.000 claims abstract description 17
- 108091007433 antigens Proteins 0.000 claims abstract description 17
- 238000001514 detection method Methods 0.000 claims abstract description 16
- 230000000274 adsorptive effect Effects 0.000 claims description 13
- 238000005304 joining Methods 0.000 claims description 10
- 230000009870 specific binding Effects 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 abstract description 4
- 230000035945 sensitivity Effects 0.000 abstract description 3
- 239000012528 membrane Substances 0.000 abstract 5
- 238000005516 engineering process Methods 0.000 description 5
- 238000003317 immunochromatography Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000002117 illicit drug Substances 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
本实用新型公开了一种碳量子点试纸条，包括底板、样品垫、碳量子点垫、吸水垫和硝酸纤维素膜，所述底板为宽度为4mm的PVC板，所述底板上依次设置有样品垫、碳量子点垫、硝酸纤维素膜和吸水垫，所述硝酸纤维素膜设置在底板的中间部位，所述硝酸纤维素膜上分别设有能与待检测抗体特异性结合的抗原线、能捕获待检测抗体IgM的第二抗体线、能与碳量子点标记抗原相结合的抗体线，所述碳量子点垫与硝酸纤维素膜的一端的衔接处重叠3mm，所述吸水垫与硝酸纤维素膜的另一端的衔接处重叠3mm。本实用新型制备成本低，高效快速检测，易于制备，使用方便快捷，灵敏度高。
The utility model discloses a carbon quantum dot test strip, which comprises a bottom plate, a sample pad, a carbon quantum dot pad, a water-absorbing pad and a nitrocellulose film, the bottom plate is a PVC board with a width of 4mm, and the bottom plate is sequentially arranged There are sample pads, carbon quantum dot pads, nitrocellulose membranes, and water-absorbing pads. The nitrocellulose membranes are arranged in the middle of the bottom plate, and the nitrocellulose membranes are respectively provided with antigens that can specifically bind to the antibodies to be detected. line, the second antibody line capable of capturing IgM of the antibody to be detected, and the antibody line capable of combining with the carbon quantum dot labeled antigen, the junction of the carbon quantum dot pad and one end of the nitrocellulose membrane overlaps by 3 mm, and the water-absorbing pad Overlap the junction with the other end of the nitrocellulose membrane by 3mm. The utility model has the advantages of low preparation cost, high efficiency and fast detection, easy preparation, convenient and fast use and high sensitivity.
Description
Technical field
The utility model relates to a kind of test strips, specifically a kind of carbon quantum dot test strips.
Background technology
Since the nineties in 20th century, immunochromatography technique is developed rapidly because of features such as its quick, easy, economic, single part detections, has been widely used in medical science detection, food quality monitoring, illicit drugs inspection and environmental monitoring.At present, immunochromatography technique is towards high sensitivity, quantitatively and the future development of multivariate detection, and likely become the sieving and diagnosis technology effective and sensitive in early days of pathogen, malignant tumour and angiocardiopathy etc.Current the most commonly colloidal gold strip, it generally can read testing result in 15 minutes, but the sensitivity of this test strips is relatively low, and complex manufacturing technology, stability and poor repeatability.It is combine having highly sensitive carbon quantum labelling technique with the immune response of high specific, for the detection analytical technology of various antigen, haptens, antibody, hormone, enzyme, fatty acid, vitamin and medicine etc. that the immunochromatography being labeled as tracer with carbon quantum dot is examined soon.Carbon quantum dot immuno analytical method has the advantages such as highly sensitive, quick, accurate, reproducible.
Utility model content
The purpose of this utility model is to provide a kind of carbon quantum dot test strips, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the utility model provides following technical scheme:
A kind of carbon quantum dot test strips, comprise base plate, sample pad, carbon quantum dot pad, adsorptive pads and nitrocellulose filter, the PVC board of described base plate to be width be 4mm, described base plate is disposed with sample pad, carbon quantum dot pad, nitrocellulose filter and adsorptive pads, described nitrocellulose filter is arranged on the middle part of base plate, described nitrocellulose filter is respectively equipped with can with the antigen line of detection antibody specific binding, the second antibody line of detection antibody IgM can be caught, the antibody line that can combine with carbon quantum dot labelled antigen, described carbon quantum dot pad be arranged on can with the side of the antigen line of detection antibody specific binding, described adsorptive pads is arranged on the side of the antibody line that can combine with carbon quantum dot labelled antigen, described carbon quantum dot pad 3mm overlapping with the joining place of one end of nitrocellulose filter, described adsorptive pads 3mm overlapping with the joining place of the other end of nitrocellulose filter.
As further program of the utility model: the overlapping 3mm of joining place of described sample pad and carbon quantum dot pad one end.
Compared with prior art, the beneficial effects of the utility model are: preparation cost is low, and efficient detection fast, is easy to preparation, convenient to use, highly sensitive.
Accompanying drawing explanation
Fig. 1 is the vertical view of carbon quantum dot test strips.
Fig. 2 is the front view of carbon quantum dot test strips.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, be clearly and completely described the technical scheme in the utility model embodiment, obviously, described embodiment is only the utility model part embodiment, instead of whole embodiments.Based on the embodiment in the utility model, those of ordinary skill in the art are not making the every other embodiment obtained under creative work prerequisite, all belong to the scope of the utility model protection.
Refer to Fig. 1 ~ 2, in the utility model embodiment, a kind of carbon quantum dot test strips, comprise base plate 1, sample pad 2, carbon quantum dot pad 3, adsorptive pads 7 and nitrocellulose filter 8, described base plate 1 for width be the PVC board of 4mm, described base plate 1 is disposed with sample pad 2, carbon quantum dot pad 3, nitrocellulose filter 8 and adsorptive pads 7, described nitrocellulose filter 8 is arranged on the middle part of base plate 1, described nitrocellulose filter 8 is respectively equipped with can with the antigen line 4 of detection antibody specific binding, the second antibody line 5 of detection antibody IgM can be caught, the antibody line 6 that can combine with carbon quantum dot labelled antigen, described carbon quantum dot pad 3 be arranged on can with the side of the antigen line 4 of detection antibody specific binding, described adsorptive pads 7 is arranged on the side of the antibody line 6 that can combine with carbon quantum dot labelled antigen, the overlapping 3mm of joining place of described sample pad 2 and carbon quantum dot pad 3 one end, described carbon quantum dot pad 3 3mm overlapping with the joining place of one end of nitrocellulose filter 8, described adsorptive pads 7 3mm overlapping with the joining place of the other end of nitrocellulose filter 8.
First nitrocellulose filter 8 is pasted onto the middle position of base plate 1 by the utility model, then carbon quantum dot pad 3 can adhered to antigen line 4 side of detection antibody specific binding, adsorptive pads 7 is adhered in antibody line 6 side that can combine with carbon quantum dot labelled antigen, again sample pad 2 is adhered to one end of carbon quantum dot pad 3, during adhesion, joining place two ends can overlapping 3mm, tight to ensure combining precision, finally the PVC base plate 1 being stained with carbon quantum dot is cut into the wide test strips of 4mm, sealing is preserved.
To those skilled in the art, obvious the utility model is not limited to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present utility model or essential characteristic, can realize the utility model in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present utility model is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the utility model.Any Reference numeral in claim should be considered as the claim involved by limiting.
In addition, be to be understood that, although this instructions is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of instructions is only for clarity sake, those skilled in the art should by instructions integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (2)
1. a carbon quantum dot test strips, comprise base plate (1), sample pad (2), carbon quantum dot pad (3), adsorptive pads (7) and nitrocellulose filter (8), it is characterized in that, described base plate (1) for width be the PVC board of 4mm, described base plate (1) is disposed with sample pad (2), carbon quantum dot pad (3), nitrocellulose filter (8) and adsorptive pads (7), described nitrocellulose filter (8) is arranged on the middle part of base plate (1), described nitrocellulose filter (8) is respectively equipped with can with the antigen line (4) of detection antibody specific binding, the second antibody line (5) of detection antibody IgM can be caught, the antibody line (6) that can combine with carbon quantum dot labelled antigen, described carbon quantum dot pad (3) be arranged on can with the side of the antigen line (4) of detection antibody specific binding, described adsorptive pads (7) is arranged on the side of the antibody line (6) that can combine with carbon quantum dot labelled antigen, the overlapping 3mm of joining place of described carbon quantum dot pad (3) and one end of nitrocellulose filter (8), the overlapping 3mm of joining place of described adsorptive pads (7) and the other end of nitrocellulose filter (8).
2. carbon quantum dot test strips according to claim 1, is characterized in that, the overlapping 3mm of joining place of described sample pad (2) and carbon quantum dot pad (3) one end.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520693313.XU CN205027758U (en) | 2015-09-09 | 2015-09-09 | Carbon quantum dot test strip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520693313.XU CN205027758U (en) | 2015-09-09 | 2015-09-09 | Carbon quantum dot test strip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205027758U true CN205027758U (en) | 2016-02-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520693313.XU Expired - Fee Related CN205027758U (en) | 2015-09-09 | 2015-09-09 | Carbon quantum dot test strip |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205027758U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10041962B1 (en) | 2017-09-28 | 2018-08-07 | National Taiwan University | Sensing paper and method of sensing abused drugs |
| WO2021095858A1 (en) * | 2019-11-14 | 2021-05-20 | インターメディック株式会社 | Method for measuring physiologically active substance |
-
2015
- 2015-09-09 CN CN201520693313.XU patent/CN205027758U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10041962B1 (en) | 2017-09-28 | 2018-08-07 | National Taiwan University | Sensing paper and method of sensing abused drugs |
| WO2021095858A1 (en) * | 2019-11-14 | 2021-05-20 | インターメディック株式会社 | Method for measuring physiologically active substance |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160210 Termination date: 20160909 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |