CN209264735U - A kind of high pass amount detecting device for two-step method immunochromatography - Google Patents
A kind of high pass amount detecting device for two-step method immunochromatography Download PDFInfo
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- CN209264735U CN209264735U CN201822082053.9U CN201822082053U CN209264735U CN 209264735 U CN209264735 U CN 209264735U CN 201822082053 U CN201822082053 U CN 201822082053U CN 209264735 U CN209264735 U CN 209264735U
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- test paper
- determinand
- paper strip
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- 238000000034 method Methods 0.000 title claims abstract description 21
- 238000003317 immunochromatography Methods 0.000 title claims abstract description 13
- 238000012360 testing method Methods 0.000 claims abstract description 73
- 238000001514 detection method Methods 0.000 claims abstract description 33
- 239000000758 substrate Substances 0.000 claims abstract description 30
- 239000003550 marker Substances 0.000 claims abstract description 27
- 238000010521 absorption reaction Methods 0.000 claims abstract description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 238000004587 chromatography analysis Methods 0.000 claims abstract description 9
- 230000000890 antigenic effect Effects 0.000 claims abstract description 8
- 208000002925 dental caries Diseases 0.000 claims abstract description 7
- 230000001681 protective effect Effects 0.000 claims description 7
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical group [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 5
- 239000002105 nanoparticle Substances 0.000 claims description 4
- 241000283707 Capra Species 0.000 claims description 3
- 241001494479 Pecora Species 0.000 claims description 3
- 239000000126 substance Substances 0.000 abstract description 9
- 238000006243 chemical reaction Methods 0.000 description 7
- 239000007788 liquid Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 230000035945 sensitivity Effects 0.000 description 4
- 239000012491 analyte Substances 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000000020 Nitrocellulose Substances 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 229920001220 nitrocellulos Polymers 0.000 description 2
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000008118 PEG 6000 Substances 0.000 description 1
- 229920002584 Polyethylene Glycol 6000 Polymers 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
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- 229910052751 metal Inorganic materials 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
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- 229920006267 polyester film Polymers 0.000 description 1
- 239000002096 quantum dot Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 239000000273 veterinary drug Substances 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a kind of high pass amount detecting device for two-step method immunochromatography, including substrate, the multiple transparent accommodating cavitys being parallel to each other are provided on the substrate;Immuno-chromatographic test paper strip is placed in the accommodating cavity, the immuno-chromatographic test paper strip includes bottom plate, it is successively overlapped with sample pad, chromatographic film, water absorption pad by chromatography direction on the bottom plate side, the chromatographic film is equipped with detection line corresponding with determinand and nature controlling line;Several specimen cups identical with immuno-chromatographic test paper strip quantity are equipped with below the substrate, the position of each specimen cup is corresponding with every immuno-chromatographic test paper strip;The antibody marker of determinand or the antigenic label of determinand are fixed in the specimen cup.It is provided with multiple transparent accommodating cavitys on the substrate of the utility model, accommodates and is placed with immuno-chromatographic test paper strip in cavity, immuno-chromatographic test paper strip is for detecting different substances, and high throughput detects while finally realizing multiple immuno-chromatographic test paper strips.
Description
Technical field
The utility model relates to technical field of biological more particularly to a kind of high throughputs for two-step method immunochromatography
Detection device.
Background technique
Immunochromatography becomes one of the important tool that food safety is examined fastly in recent years.In use, often exist
This needs the needs of Multiple detection.When conventional method solves this problem, often there are two types of methods.
A kind of method is that the setting of a plurality of detection line is carried out in single test strips, to realize Multiple detection.But for just
The property taken and test paper strips are limited, and realize that 5 re-detections have been most on the market at present in single test strips, it is difficult to meet
Demand.
Another method is using multiple test strips while to be detected.CN207336544U discloses a kind of high-throughput agriculture
The immuno-chromatography detection device of residue of veterinary drug comprising for placing the sample area of agricultural samples liquid to be measured and being integrated in one
The different remaining immuno-chromatographic test paper strips of agricultural and veterinary chemicals of at least two detections of body, the sample pad of the immuno-chromatographic test paper strip and institute
State the agricultural samples liquid to be measured contact in sample area.The immuno-chromatographic test paper strip includes bottom plate, on the bottom plate side
It is successively overlapped with sample pad, bonding pad, chromatographic film, water absorption pad by chromatography direction, the chromatographic film is equipped with and agricultural and veterinary chemicals to be measured
Corresponding detection line and nature controlling line.CN201993317U discloses a kind of Multichannel synchronous quick detecting box, including box body
And test strips, box body include pedestal and panel, wherein pedestal is equipped with the fixing groove of installation test strips, and panel is equipped with well
Window as the result is shown, by sample pad, gold mark thing bonding pad, reaction film and water absorption pad, successively mutually overlap joint is pasted onto liner plate to test strips
On be made, reaction film is with being printed with the nitrocellulose filter of stealthy detection line and control line;It is characterized by: the well
Connect sample cavity;The fixing groove be it is multiple, fixing groove one end is test strips through-hole, through-hole bore and test strips width, thickness
Degree is adapted;The sample pad on test strips head is connected to by respective test strips through-hole with sample cavity.Above-mentioned fixing groove is 3-5
Item.It is using multiple test strips while to be detected, but its test strips includes five components in above patent document, respectively
For sample pad, bonding pad, chromatographic film, water absorption pad and bottom plate, wherein sample pad, bonding pad, chromatographic film, water absorption pad are successively mutual
Overlap joint, since marker is to be pre-dried to be fixed on bonding pad, the detection nothing in sample is in the same of dissolution marker
When reacted with the marker on bonding pad, but since the reaction time is short, dissolution is insufficient, immune combine not exclusively etc. causes to examine
Survey the low problem of sensitivity.
In order to solve the problems, such as that detection sensitivity is low, immunochromatography, i.e. sample are often carried out using two-step method in the prior art
Product are first added in the specimen cup containing antibody/antigen marker, reaction a period of time;Then test strips, test strips packet are placed into
Containing four components, respectively sample pad, chromatographic film, water absorption pad and bottom plate, wherein sample pad, chromatographic film, water absorption pad are successively mutual
Mutually overlap.Entire detection process is carried out in two steps, so reaction is more abundant, sensitivity is improved.
But it when carrying out immunochromatography using two-step method in the prior art, in order to realize Multiple detection, needs one by one
Test strips are put into one by one in each specimen cup.Such way has following defect.First is that being easy to produce time error, (every is put
The time entered is different), operator is easy confusion in multiple test strips use processes, and since part chromatography process is less than 1
Minute, the time of several seconds has resulted in large error.Second is that test strips are easy the pollutant because in operator's hand or gloves
And cause interference with, and this interference can only often be completed in chromatography, could be found after as a result coming out.Third is that the pollution in environment
Object, dust etc. are readily incorporated into test strips, and unstable result even result is caused to disappear.Fourth is that when using instrument readings,
It needs to arrange test strips neat, be more troublesome.
Utility model content
In order to solve above-mentioned the deficiencies in the prior art, the utility model provides a kind of high pass for two-step method immunochromatography
Amount detecting device.
Technical problem to be solved in the utility model is achieved by the following technical programs:
A kind of high pass amount detecting device for two-step method immunochromatography, including substrate are provided on the substrate mutually
Parallel multiple transparent accommodating cavitys, the accommodating cavity are convexly equipped in the substrate surface;It is placed in the accommodating cavity
Immuno-chromatographic test paper strip, the immuno-chromatographic test paper strip include bottom plate, are successively overlapped on the bottom plate side by chromatography direction
There are sample pad, chromatographic film, water absorption pad, the chromatographic film is equipped with detection line corresponding with determinand and nature controlling line;It is described
Be equipped with the specimen cup of several array arrangements identical with immuno-chromatographic test paper strip quantity below substrate, the position of each specimen cup with
Every immuno-chromatographic test paper strip is corresponding;The antibody marker of determinand or the antigenic mark of determinand are fixed in the specimen cup
Object.
Further, the accommodating cavity is closed at one end, open at one end, and the opening of the accommodating cavity is towards the sample
Bottom of a cup portion.
Further, the sample pad of the immuno-chromatographic test paper strip exceeds the edge of the substrate.
Further, the marker is colloidal gold or fluorescent nano particle.
Further, the antibody marker of the determinand is the block of the antibody-marker object conjugate of determinand;Institute
The antigenic label for stating determinand is antigen-carrier albumen-marker conjugate block of determinand;In the detection line
It is coated with the antibody of determinand or the antigen-carrier protein conjugate of determinand, is coated with goat anti-rabbit igg on the nature controlling line
Antibody or sheep anti-mouse igg antibody.
Further, the marker is colloidal gold or fluorescent nano particle.
Further, the substrate is molded with accommodating cavity to be integrated.
Further, the substrate is detachably connected with accommodating cavity.
It further, further include protective case, the protective case is detachably arranged at the open end of the accommodating cavity.
The utility model has the following beneficial effects:
It is provided with multiple transparent accommodating cavitys on the substrate of the utility model, accommodates in cavity and is placed with immunity-chromatography test
Paper slip, immuno-chromatographic test paper strip is for detecting different substances, high pass while finally realizing multiple immuno-chromatographic test paper strips
Amount detection.
In the utility model, according to actually detected demand, can select the immuno-chromatographic test paper strip of detection different material with
Specimen cup combination, meets different demands.
In the utility model, after the completion of immuno-chromatographic test paper strip detection, arrange uniform, it can be very in readout instrument reading
It is easily accurate to read, without being one by one aligned test strips, reduce error.
In the utility model, immuno-chromatographic test paper strip is placed in transparent accommodating cavity, so that immuno-chromatographic test paper strip sheet
Body is not easy to receive the pollution (gloves or hand) in operator's operating process, operates more convenient.
In the utility model, reduce the pollution of floating material in environment, so that result is more reliable and stable.
Existing immuno-chromatographic test paper strip is made of 4 parts, i.e., successively by sample pad, bonding pad, chromatographic film,
The bottom plate that water absorption pad passes sequentially through adhesive is successively mutually lapped, and is not had in the immuno-chromatographic test paper strip of the utility model
There is bonding pad, marker conjugate coated in existing bonding pad is set in specimen cup, improves in traditional test strip and ties
It closes and react and be not thorough on pad, not exclusively, the defects of low efficiency, so that determinand and marker conjugate are thorough in homogeneous system
Reaction improves sensitivity.
Detailed description of the invention
Fig. 1 is the perspective view of the utility model.
In figure: 1, accommodating cavity, 2, substrate, 3, immuno-chromatographic test paper strip, 4, specimen cup.
Specific embodiment
The utility model is described in detail with reference to the accompanying drawings and examples.
A kind of high pass amount detecting device for two-step method immunochromatography, including substrate, accommodating cavity, immune chromatography test paper
Item and specimen cup.
The multiple transparent accommodating cavitys being parallel to each other are provided on the substrate, the accommodating cavity is convexly equipped in the base
Plate surface;The accommodating inside cavity is hollow, is placed with immuno-chromatographic test paper strip in the accommodating cavity.
In the utility model, the not specific modes of emplacement limited between accommodating cavity and immuno-chromatographic test paper strip, as long as
So that immuno-chromatographic test paper strip is easy to fix and remove out accommodating cavity, those skilled in the art can be according to actual needs
It is set.Preferably, the accommodating cavity and immuno-chromatographic test paper strip frictionally secure, specifically, the accommodating cavity
Inner wall is equipped with the frictional layer for increasing frictional force, and the accommodating cavity physical efficiency is frictionally secured by frictional layer and test strips.
The accommodating cavity is closed at one end, open at one end, and the opening of the accommodating cavity is towards the specimen cup bottom.Institute
The accommodating cavity stated only is provided with an opening in the part towards specimen cup bottom of a cup, and rest part seals and each accommodating
Cavity is isolated, so that immuno-chromatographic test paper strip itself is not easy to receive the pollution (gloves or hand) in operator's operating process,
It operates more convenient.
The material of the substrate is impermeable material, can be plastics, metal, glass etc., but be not limited to as an example
This.
In the utility model, the quantity of accommodating cavity is not particularly limited, those skilled in the art can be according to reality
Detection needs to carry out flexible setting, and as an example, the quantity of the accommodating cavity can be 6,8,10.
In the utility model, the shape of accommodating cavity is not particularly limited, it is preferable that the accommodating cavity is platypelloid type
Structure.
The accommodating cavity is alternatively arranged.The substrate can be molded with accommodating cavity to be integrated, be also possible to
It is detachably connected.
The immuno-chromatographic test paper strip includes bottom plate, is successively overlapped with sample by chromatography direction on the bottom plate side
Pad, chromatographic film, water absorption pad, the chromatographic film are equipped with detection line corresponding with determinand and nature controlling line.Specifically, described
Immuno-chromatographic test paper strip includes bottom plate, sample pad, chromatographic film, water absorption pad, and the bottom plate side is equipped with sample pad, and the other side is equipped with
Water absorption pad is equipped with chromatographic film, neighboring samples pad and chromatographic film in the overlapping connection in junction, the layer between sample pad and water absorption pad
Film and water absorption pad are analysed in the overlapping connection in junction, the middle part of chromatographic film is equipped with detection line and nature controlling line, detection line close to sample pad,
The sample pad of the immuno-chromatographic test paper strip exceeds the edge of the substrate.
The sample pad is polyester film, glass or filter paper with sample filtering function.
The water absorption pad is blotting paper;The chromatographic film is nitrocellulose filter or cellulose acetate film.
The specimen cup of several array arrangements identical with immuno-chromatographic test paper strip quantity, each sample are equipped with below the substrate
The position of product cup is corresponding with every immuno-chromatographic test paper strip;The antibody marker or to be measured of determinand is fixed in the specimen cup
The antigenic label of object.
The marker is the substance that can be used to identify and detect acquisition signal, such as colloidal gold, but not limited to this, make
For citing, latex, fluorescent nano particle, quantum dot or up-conversion luminescence substance etc. can also be.The utility model not only can be with
Meet the testing requirements of fast qualitative, Effective judgement can also be carried out to sample result and sample amounts are analyzed.
The antibody marker of the determinand is the block of the antibody-marker object conjugate of determinand;The determinand
Antigenic label be determinand antigen-carrier albumen-marker conjugate block;Be coated in the detection line to
The antibody of object or the antigen-carrier protein conjugate of determinand are surveyed, is coated with goat anti-rabbit igg antibody or sheep on the nature controlling line
Dynamics.
The cup that specimen cup can have any shape, usually straight barrel type or the cup with the narrow Bottom Shape of wide opening.
Multiple accommodating cavitys can provide multiple immuno-chromatographic test paper strips simultaneously and be detected, while collocation is fixed with correspondence
The specimen cup of the marker of detectable substance, may be implemented high-throughput detection, improve detection efficiency, and can according to actual needs with
Meaning assembling.
The sample pad of immuno-chromatographic test paper strip is exposed to except accommodating cavity, and the sample pad of the immuno-chromatographic test paper strip is super
The edge of the substrate out.
In order to further realize the sealing to immuno-chromatographic test paper strip sample pad, the utility model further includes protective case, institute
State the open end that protective case is detachably arranged at the accommodating cavity.The utility model does not make especially dismountable concrete mode
It limits, the conventional arrangement of this field can be used.When not detecting, protective case is fixed on accommodating cavity open end, with realization pair
It is exposed to the sealing of the sample pad of the immuno-chromatographic test paper strip except accommodating cavity, prevents sample pad from pollution;When detecting, it will protect
Sheath is disassembled from accommodating cavity, and sample pad is contacted with the sample liquid of specimen cup.
Information registration label is also posted on water absorption pad and specimen cup, it is to be measured to be printed with correspondence on the information registration label
The title of object facilitates user to recognize kind.
The utility model application method is: acquisition sample handles sample to obtain analyte sample fluid, by sample to be tested
Liquid is put into specimen cup, and analyte sample fluid first dissolves out the antigenic label of the antibody marker of determinand or determinand, to be measured
Antigen in sample liquid is sufficiently reacted with marker simultaneously, then will be assembled immuno-chromatographic test paper strip while will be inserted into each
In specimen cup, it is anti-that the sample pad of the immuno-chromatographic test paper strip contacts progress immunochromatography with the analyte sample fluid in specimen cup
It answers, visually observes or the power of each detection line signal in instrument scanning chromatographic film, determine the more of respective objects substance in sample
Widow, the content of respective objects substance is also higher in signal more weak sample.Entire detection process is carried out in two steps, i.e., immune to combine
And Immune competition, due to this feature, so reaction is sufficiently, sensitive raising is easy to operate, and detection is that specific antigen-antibody is anti-
It answers, so having the characteristics that high specificity, accuracy are high.
As a further improvement, further include release agent in the specimen cup, the release agent be casein, BSA or
In PEG6000 any one or at least two combination.In the utility model, release agent is additionally added in specimen cup, so that
The combination of the antibody and marker of determinand is more stable, further reduced the detection limit of immuno-chromatographic test paper strip.
Finger cot ring is additionally provided on the substrate, specifically, the substrate is close to the accommodating cavity closed end side
Equipped with finger cot ring, it is preferred that there are two finger cot ring is arranged altogether, and finger cot ring is a kind of component of ABS material.This is practical
By the way that finger cot ring is arranged on substrate in novel, it can play convenient for stablizing the effect taken, increase the stability of detection.
The above-mentioned embodiments merely express the embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
Therefore it cannot be interpreted as that a limitation on the scope of the patent of the present invention, as long as using the form institute of equivalent substitution or equivalent transformation
The technical solution of acquisition, shall fall within the scope of the present invention.
Claims (8)
1. a kind of high pass amount detecting device for two-step method immunochromatography, which is characterized in that it includes substrate, on the substrate
The multiple transparent accommodating cavitys being parallel to each other are provided with, the accommodating cavity is convexly equipped in the substrate surface;The accommodating cavity
Immuno-chromatographic test paper strip is placed in body, the immuno-chromatographic test paper strip includes bottom plate, and chromatography side is pressed on the bottom plate side
To sample pad, chromatographic film, water absorption pad is successively overlapped with, the chromatographic film is equipped with detection line corresponding with determinand and matter
Control line;The specimen cup of several array arrangements identical with immuno-chromatographic test paper strip quantity, each sample are equipped with below the substrate
The position of cup is corresponding with every immuno-chromatographic test paper strip;The antibody marker or determinand of determinand are fixed in the specimen cup
Antigenic label.
2. high pass amount detecting device as described in claim 1, which is characterized in that the accommodating cavity is closed at one end, and one end is opened
Mouthful, the opening of the accommodating cavity is towards the specimen cup bottom.
3. high pass amount detecting device as described in claim 1, which is characterized in that the sample pad of the immuno-chromatographic test paper strip is super
The edge of the substrate out.
4. high pass amount detecting device as described in claim 1, which is characterized in that the marker is colloidal gold or fluorescence nano
Particle.
5. high pass amount detecting device as described in claim 1, which is characterized in that the antibody marker of the determinand is to be measured
The block of the antibody-marker object conjugate of object;The antigenic label of the determinand is the antigen-carrier albumen-of determinand
The block of marker conjugate;The antibody of determinand or the antigen-carrier albumen of determinand are coated in the detection line
Conjugate is coated with goat anti-rabbit igg antibody or sheep anti-mouse igg antibody on the nature controlling line.
6. high pass amount detecting device as described in claim 1, which is characterized in that the substrate is integrated note with accommodating cavity
It moulds.
7. high pass amount detecting device as described in claim 1, which is characterized in that the substrate detachably connects with accommodating cavity
It connects.
8. high pass amount detecting device as described in claim 1, which is characterized in that further include protective case, the protective case is removable
It is set to the open end of the accommodating cavity with unloading.
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CN201822082053.9U CN209264735U (en) | 2018-12-12 | 2018-12-12 | A kind of high pass amount detecting device for two-step method immunochromatography |
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CN201822082053.9U CN209264735U (en) | 2018-12-12 | 2018-12-12 | A kind of high pass amount detecting device for two-step method immunochromatography |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113075176A (en) * | 2021-03-17 | 2021-07-06 | 西安医学院 | Tumor marker multi-analysis device |
WO2022057200A1 (en) * | 2020-09-16 | 2022-03-24 | 深圳市易瑞生物技术股份有限公司 | Two-step multiplex immunochromatographic detection fastener |
CN114544572A (en) * | 2022-02-22 | 2022-05-27 | 上海艾瑞德生物科技有限公司 | BNP fluorescent quantitative detection test strip, kit and preparation method thereof |
-
2018
- 2018-12-12 CN CN201822082053.9U patent/CN209264735U/en active Active
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022057200A1 (en) * | 2020-09-16 | 2022-03-24 | 深圳市易瑞生物技术股份有限公司 | Two-step multiplex immunochromatographic detection fastener |
CN113075176A (en) * | 2021-03-17 | 2021-07-06 | 西安医学院 | Tumor marker multi-analysis device |
CN113075176B (en) * | 2021-03-17 | 2022-11-01 | 西安医学院 | Tumor Marker Multiplex Analysis Device |
CN114544572A (en) * | 2022-02-22 | 2022-05-27 | 上海艾瑞德生物科技有限公司 | BNP fluorescent quantitative detection test strip, kit and preparation method thereof |
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