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CN204142525U - A kind of micro liquid sampling sample adding device - Google Patents

A kind of micro liquid sampling sample adding device Download PDF

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Publication number
CN204142525U
CN204142525U CN201420635386.9U CN201420635386U CN204142525U CN 204142525 U CN204142525 U CN 204142525U CN 201420635386 U CN201420635386 U CN 201420635386U CN 204142525 U CN204142525 U CN 204142525U
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liquid storage
sampling
storage tube
adding device
sampling head
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薛源
张冠斌
赵凯军
陈铖
盛涛
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CapitalBio Corp
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CapitalBio Corp
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Abstract

本实用新型公开了一种微量液体取样加样装置。它包括一取样头、一储液管和一加样头;所述取样头上连接有定量毛细管;所述储液管的一端口密封有薄膜,且连接所述薄膜处设有凸台;所述储液管的另一端与所述加样头相配合,且所述加样头能沿所述储液管的长度方向移动;所述取样头能与所述储液管的所述薄膜端相配合,使所述定量毛细管刺破所述薄膜并延伸至所述储液管的腔体内。本实用新型微量液体取样加样装置,通用性强,结构设计合理,结合了定量取样、试剂稀释混合、加样多种功能于一体,不但节省了采购多种微量取样仪器的采购和维护成本,还有效的简化了操作步骤,大大提高了实验效率。

The utility model discloses a trace liquid sampling and adding device. It includes a sampling head, a liquid storage tube and a sampling head; the sampling head is connected with a quantitative capillary; a port of the liquid storage tube is sealed with a film, and a boss is provided at the place where the film is connected; The other end of the liquid storage tube is matched with the sampling head, and the sampling head can move along the length direction of the liquid storage tube; the sampling head can be connected with the film end of the liquid storage tube In cooperation, the quantitative capillary pierces the film and extends into the cavity of the liquid storage tube. The utility model micro-liquid sampling and adding device has strong versatility, reasonable structural design, and combines quantitative sampling, reagent dilution and mixing, and adding multiple functions in one, which not only saves the purchase and maintenance costs of purchasing various micro-sampling instruments, It also effectively simplifies the operation steps and greatly improves the experimental efficiency.

Description

一种微量液体取样加样装置A micro liquid sampling and adding device

技术领域technical field

本实用新型涉及一种微量液体取样加样装置。The utility model relates to a trace liquid sampling and adding device.

背景技术Background technique

随着检测行业的不断发展,微量液体的检测应用越来越广泛,由于检测样本的微量化,在检测时需要借助微量取样装置来完成。然而现有大多数的微量取样器仅仅只能完成取样的功能,后续还需要借助移液枪来定量和转移微量样本与试剂进行反应,需要大量微量工具的配合才能完成,不但极大的增加了器械购置成本和维护成本,而且步骤繁琐,效率低下。现有市面上存在的一种定量虹吸滴液管,虽然取样和混合和本实用新型相比在取样和液体混合方面使用都十分简单方便,但前者在加样方面仅仅只能采取滴加液体的方式加样而无法做到注射式加样,由于需要挤压试剂管,如果用力过猛则很可能造成缝隙间的漏液;此外由于挤压的试剂管具有弹性,操作起来很不方便,往往会由于操作者的挤压力不够而导致液体不能很好的被挤压排除,而一旦在操作过程中撤力,很容易造成回吸现象。With the continuous development of the detection industry, the detection of trace liquids is becoming more and more widely used. Due to the small amount of detection samples, it is necessary to use a trace sampling device to complete the detection. However, most of the existing micro samplers can only complete the sampling function, and then need to use a pipette to quantify and transfer micro samples and reagents for reaction, which requires the cooperation of a large number of micro tools, which not only greatly increases Equipment purchase cost and maintenance cost, and the steps are cumbersome and inefficient. A kind of quantitative siphon dropper that exists on the existing market, although sampling and mixing are all very simple and convenient in sampling and liquid mixing compared with the utility model, but the former can only take the method of dripping liquid in terms of adding samples. It is not possible to add samples by injection, because the reagent tube needs to be squeezed, and if the force is too strong, it may cause leakage between the gaps; in addition, because the squeezed reagent tube is elastic, it is very inconvenient to operate, and often The liquid cannot be squeezed out well due to insufficient squeezing force of the operator, and once the force is withdrawn during the operation, it is easy to cause back-suction.

实用新型内容Utility model content

本实用新型的目的是提供一种微量液体取样加样装置,所述取样加样装置不但能够进行微量液体样品的定量取样,还可以进一步完成样品的稀释混合与加样,解决了现有技术取样、混合、加样步骤的繁琐和效率低下等问题。The purpose of the utility model is to provide a micro-liquid sampling and adding device, which can not only perform quantitative sampling of micro-liquid samples, but also further complete sample dilution, mixing and sampling, which solves the problem of sampling in the prior art. , Mixing, cumbersome and inefficient steps of adding samples.

本实用新型所提供的微量液体取样加样装置,包括一取样头、一储液管和一加样头;The micro liquid sampling and adding device provided by the utility model comprises a sampling head, a liquid storage tube and a sampling head;

所述取样头上连接有定量毛细管;A quantitative capillary is connected to the sampling head;

所述储液管的一端口密封有薄膜,且连接所述薄膜处设有凸台;所述储液管的另一端与所述加样头相配合,且所述加样头能沿所述储液管的长度方向移动;One port of the liquid storage tube is sealed with a film, and a boss is provided at the place where the film is connected; the other end of the liquid storage tube is matched with the sampling head, and the sampling head can move along the The length direction movement of the liquid storage tube;

所述取样头能与所述储液管的所述薄膜端相配合,使所述定量毛细管刺破所述薄膜并延伸至所述储液管的腔体内。The sampling head can cooperate with the film end of the liquid storage tube, so that the quantitative capillary pierces the film and extends into the cavity of the liquid storage tube.

所述的微量液体取样加样装置中,所述储液管的一端连接一环状体形成所述凸台,所述取样头与所述储液管相配合时,所述取样头会与所述凸台相抵,进而实现所述取样头与所述储液管之间的限位;In the trace liquid sampling and adding device, one end of the liquid storage tube is connected to an annular body to form the boss, and when the sampling head cooperates with the liquid storage tube, the sampling head will match the The above-mentioned boss is offset, thereby realizing the limit between the sampling head and the liquid storage tube;

所述环状体的内壁上设有若干个环状突起,所述环状突起的设置能够起到防止所述储液管内的液体流出的作用。The inner wall of the annular body is provided with several annular protrusions, and the arrangement of the annular protrusions can prevent the liquid in the liquid storage tube from flowing out.

所述的微量液体取样加样装置中,所述储液管的内壁上设有若干个环状突起,其具有防止所述加样头从所述储液管中脱落的作用,同时在加样过程中起到限位和防止液体漏出的作用。In the micro-liquid sampling and adding device, the inner wall of the liquid storage tube is provided with several annular protrusions, which have the function of preventing the sampling head from falling off from the liquid storage tube. Play a role in limiting and preventing liquid leakage during the process.

所述的微量液体取样加样装置中,所述加样头的腔体由一端至其出口端由大变小,在加样时,将所述加样头向所述储液管的另一端移动时,则所述储液管内的液体被压缩,压力增大,所述加样头的腔体的上述设置有助于液体从其出口端流出。In the micro-volume liquid sampling and adding device, the cavity of the sampling head changes from one end to the outlet end thereof. When moving, the liquid in the liquid storage tube is compressed and the pressure increases, and the above arrangement of the cavity of the sampling head helps the liquid to flow out from the outlet port.

所述的微量液体取样加样装置中,由大口径端至小口径端,所述加样头依次由圆柱体a、圆台体和圆柱体b组成,即将所述圆柱体a与所述圆台体的大口径端相连接,所述圆台体的小口径端与所述圆柱体b相连接。In the trace liquid sampling and adding device, from the large-diameter end to the small-caliber end, the sampling head is composed of a cylinder a, a frustum of a cone and a cylinder b in sequence, that is, the cylinder a and the frustum of a cone The large-diameter end of the frustum is connected, and the small-diameter end of the frustum is connected with the cylinder b.

本实用新型微量液体取样加样装置具有如下优点:The micro liquid sampling and adding device of the utility model has the following advantages:

本实用新型微量液体取样加样装置,通用性强,结构设计合理,结合了定量取样、试剂稀释混合、加样多种功能于一体,不但节省了采购多种微量取样仪器的采购和维护成本,还有效的简化了操作步骤,大大提高了实验效率。The utility model micro-liquid sampling and adding device has strong versatility, reasonable structural design, and combines quantitative sampling, reagent dilution and mixing, and adding multiple functions in one, which not only saves the purchase and maintenance costs of purchasing various micro-sampling instruments, It also effectively simplifies the operation steps and greatly improves the experimental efficiency.

附图说明Description of drawings

图1是本实用新型微量液体取样加样装置的外观示意图。Fig. 1 is a schematic diagram of the appearance of the micro-liquid sampling and adding device of the present invention.

图2是本实用新型微量液体取样加样装置中储液管和加样头部分的示意图。Fig. 2 is a schematic view of the liquid storage tube and the sampling head in the micro-liquid sampling and adding device of the present invention.

图3是本实用新型微量液体取样加样装置中储液管与取样头取样头相配合时的示意图。Fig. 3 is a schematic diagram of the cooperation between the liquid storage tube and the sampling head in the micro-liquid sampling and adding device of the present invention.

图中各标记如下:The marks in the figure are as follows:

1取样头、2密封膜、3储液管、4储液腔、5环状突起Ⅰ、6环状突起Ⅱ、7加样头、8凸台。1 Sampling head, 2 Sealing film, 3 Liquid storage tube, 4 Liquid storage chamber, 5 Annular protrusion I, 6 Annular protrusion II, 7 Sample adding head, 8 Boss.

具体实施方式Detailed ways

下面结合附图对本实用新型作进一步说明,但本实用新型并不局限于以下实施例。The utility model will be further described below in conjunction with the accompanying drawings, but the utility model is not limited to the following embodiments.

如图1所示,为本实用新型微量液体取样加样装置的外观示意图,它包括一个取样头1、一个储液管3和一个加样头7。如图3所示,在取样头1的一端连接有定量毛细管(图中未标);如图2所示,在储液管3的一端密封有密封膜2,且该端连接一个环状体(图中未标),该环状体与储液管3的一端形成一个凸台8,取样头1能够与储液管3的一端相配合,相配合时,取样头1会与凸台8相抵,进而实现取样头1与储液管3之间的限位。取样头1与储液管3相配合时,取样头1上的定量毛细管刺破密封膜2并延伸至储液管3的腔体内。另外,在与储液管3相连接的环状体的内壁上设有多个环状突起Ⅰ5,其具有防止储液管3内的液体流出的作用。储液管3的另一端与加样头7相配合,且加样头7能沿储液管3的长度方向移动,且在储液管3的内壁上设有多个环状突起Ⅱ6,如图2中的局部放大图所示,其具有防止加样头7从储液管3中脱落的作用。As shown in FIG. 1 , it is a schematic diagram of the appearance of the micro-liquid sampling and adding device of the present invention, which includes a sampling head 1 , a liquid storage tube 3 and a sampling head 7 . As shown in Figure 3, one end of the sampling head 1 is connected with a quantitative capillary (not marked); (Not marked in the figure), this annular body forms a boss 8 with one end of liquid storage pipe 3, and sampling head 1 can match with one end of liquid storage pipe 3, and when matching, sampling head 1 can be with boss 8 offset, thereby realizing the limitation between the sampling head 1 and the liquid storage tube 3 . When the sampling head 1 cooperates with the liquid storage tube 3 , the quantitative capillary on the sampling head 1 pierces the sealing film 2 and extends into the cavity of the liquid storage tube 3 . In addition, a plurality of annular protrusions I5 are provided on the inner wall of the annular body connected to the liquid storage tube 3 to prevent the liquid in the liquid storage tube 3 from flowing out. The other end of the liquid storage tube 3 is matched with the sampling head 7, and the sampling head 7 can move along the length direction of the liquid storage tube 3, and a plurality of annular protrusions II6 are arranged on the inner wall of the liquid storage tube 3, such as As shown in the partial enlarged view in FIG. 2 , it has the function of preventing the sampling head 7 from falling off from the liquid storage tube 3 .

为了便于加样,将加样头7的腔体设置成由其一端至其出口端由大变小的形式,如图2和图3所示,由大口径端至小口径端,该加样头7依次由圆柱体a、圆台体和圆柱体b组成,即将圆柱体a与圆台体的大口径端相连接,圆台体的小口径端与圆柱体b的相连接,在加样时,将加样头7向储液管3的另一端移动时,则储液管3内的液体被压缩,压力增大,加样头7的腔体的上述设置有助于液体从其出口端流出。In order to facilitate sample addition, the cavity of the sample injection head 7 is set to a form that changes from one end to its outlet end, as shown in Figure 2 and Figure 3, from the large-caliber end to the small-caliber end, the sample addition The head 7 is composed of a cylinder a, a frustum of a cone and a cylinder b in turn, that is, the cylinder a is connected with the large diameter end of the cone, and the small diameter end of the cone is connected with the cylinder b. When adding a sample, the When the sampling head 7 moves to the other end of the liquid storage tube 3, the liquid in the liquid storage tube 3 is compressed and the pressure increases. The above-mentioned arrangement of the cavity of the sampling head 7 helps the liquid to flow out from its outlet end.

下面详细说明说明本实用新型微量液体取样加样装置的使用过程:The following describes in detail the use process of the micro-volume liquid sampling and adding device of the present invention:

当需要进行微量液体的取样时,用取样头1的定量毛细管利用虹吸现象吸取样品,不同的毛细管的尺寸可用于吸取不同体积的微量液体。当定量毛细管吸取完样品后,用其刺破储液管3顶部的密封膜2并使取样头1的中部密封于储液管3的储液腔4中,而取样头1与储液管3上的凸台8相抵,实现取样头1与储液管3之间的限位,环状体上的环状突起Ⅰ5与取样头1配合防止储液腔4内的内液体流出。手持储液管3上半部分向下甩动,使定量毛细管内的样品进入储液腔4中,然后上下颠倒该微量液体取样加样装置,达到所取微量样品和储液腔内试剂混合的作用;或者将加样头7与储液管3往复相对运动以达到液体混匀的效果。When it is necessary to sample a small amount of liquid, the quantitative capillary of the sampling head 1 is used to draw the sample through the siphon phenomenon, and different sizes of the capillary can be used to absorb a small amount of liquid of different volumes. After the quantitative capillary has sucked the sample, use it to puncture the sealing film 2 on the top of the liquid storage tube 3 and seal the middle part of the sampling head 1 in the liquid storage cavity 4 of the liquid storage tube 3, and the sampling head 1 and the liquid storage tube 3 The boss 8 on the top offsets to realize the limit between the sampling head 1 and the liquid storage tube 3, and the annular protrusion I5 on the annular body cooperates with the sampling head 1 to prevent the internal liquid in the liquid storage chamber 4 from flowing out. Hold the upper part of the liquid storage tube 3 and shake it downwards, so that the sample in the quantitative capillary enters the liquid storage chamber 4, and then turn the micro-liquid sampling and adding device upside down to achieve the mixing of the micro-sample and the reagent in the liquid storage chamber. role; or reciprocating relative movement between the sampling head 7 and the liquid storage tube 3 to achieve the effect of liquid mixing.

当本实用新型用于加样时,握住取样头1和储液管3向下推动加样头7,则加样头7向储液管3的腔体内部移动,使储液腔4逐渐缩小,同时储液腔4内试剂被挤出储液腔4,进而完成加样。When the utility model is used for adding samples, hold the sampling head 1 and the liquid storage tube 3 and push the sampling head 7 downward, then the sampling head 7 moves to the inside of the cavity of the liquid storage tube 3, so that the liquid storage chamber 4 gradually shrink, and at the same time, the reagent in the liquid storage chamber 4 is squeezed out of the liquid storage chamber 4, and then the sample addition is completed.

本实用新型微量液体取样加样装置,结合了定量取样,试剂稀释混合,加样多种功能于一体,不但节省了采购多种微量取样仪器的采购和维护成本,还有效的简化了操作步骤,使其易于操作,大大提高了实验效率。The micro-liquid sampling and adding device of the utility model combines quantitative sampling, reagent dilution and mixing, and multiple functions of adding samples, which not only saves the purchase and maintenance costs of purchasing various micro-sampling instruments, but also effectively simplifies the operation steps. It is easy to operate and greatly improves the experimental efficiency.

Claims (5)

1. a micro liquid sampling sample adding device, is characterized in that: it comprises a sampling head, a liquid storage pipe and a feed head;
Described sampling head is connected with quantitative capillary tube;
The Single port of described liquid storage pipe is sealed with film, and connects described film place and be provided with boss; The other end of described liquid storage pipe matches with described feed head, and described feed head can move along the length direction of described liquid storage pipe;
Described sampling head can match with the described film end of described liquid storage pipe, makes described quantitative capillary tube puncture described film and extends in the cavity of described liquid storage pipe.
2. sampling sample adding device according to claim 1, is characterized in that: one end of described liquid storage pipe connects a ring bodies and forms described boss;
The inwall of described ring bodies is provided with several circular protrusions.
3. sampling sample adding device according to claim 1 and 2, is characterized in that: the inwall of described liquid storage pipe is provided with several circular protrusions.
4. sampling sample adding device according to claim 3, is characterized in that: the cavity of described feed head by one end to its endpiece from large to small.
5. sampling sample adding device according to claim 4, is characterized in that: by heavy caliber end to small-caliber end, described feed head is made up of right cylinder a, Rotary-table and right cylinder b successively.
CN201420635386.9U 2014-10-29 2014-10-29 A kind of micro liquid sampling sample adding device Expired - Lifetime CN204142525U (en)

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CN105181981A (en) * 2015-08-11 2015-12-23 厦门大学 Method for rapid high-sensitivity on-site quantitative detection
CN105784416A (en) * 2016-04-26 2016-07-20 德莫德(苏州)机械科技有限公司 Collector with micro quantitative sampling and sample adding function
CN106854674A (en) * 2015-12-08 2017-06-16 上海交通大学 A kind of nucleic acid high flux method for quick based on capillary microarray
TWI604182B (en) * 2016-04-26 2017-11-01 諾貝爾生物有限公司 Syringe assembly and method of using the same
CN107525693A (en) * 2017-08-17 2017-12-29 基蛋生物科技股份有限公司 A kind of quantitative sampling sample adding device
WO2018006519A1 (en) * 2016-07-06 2018-01-11 江苏科华医疗器械科技有限公司 Pipette set
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WO2019014958A1 (en) * 2017-07-18 2019-01-24 杭州优思达生物技术有限公司 Biological sample collecting and processing bottle, and method of use therefor
CN112284825A (en) * 2020-10-19 2021-01-29 华兰生物工程重庆有限公司 Volatile substance sealing and sampling device capable of being used independently
CN117165416A (en) * 2023-11-03 2023-12-05 苏州雅睿生物技术股份有限公司 Dilution tube, nucleic acid detection device and detection method thereof
CN118067461A (en) * 2024-04-17 2024-05-24 安丘金山机械制造有限公司 Sampling device for mixed liquid detection

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105181981A (en) * 2015-08-11 2015-12-23 厦门大学 Method for rapid high-sensitivity on-site quantitative detection
CN106854674A (en) * 2015-12-08 2017-06-16 上海交通大学 A kind of nucleic acid high flux method for quick based on capillary microarray
CN105784416A (en) * 2016-04-26 2016-07-20 德莫德(苏州)机械科技有限公司 Collector with micro quantitative sampling and sample adding function
TWI604182B (en) * 2016-04-26 2017-11-01 諾貝爾生物有限公司 Syringe assembly and method of using the same
WO2018006519A1 (en) * 2016-07-06 2018-01-11 江苏科华医疗器械科技有限公司 Pipette set
WO2019014958A1 (en) * 2017-07-18 2019-01-24 杭州优思达生物技术有限公司 Biological sample collecting and processing bottle, and method of use therefor
CN107525693B (en) * 2017-08-17 2018-07-13 基蛋生物科技股份有限公司 A kind of quantitative sampling sample adding device
CN107525693A (en) * 2017-08-17 2017-12-29 基蛋生物科技股份有限公司 A kind of quantitative sampling sample adding device
CN108318287A (en) * 2018-01-23 2018-07-24 上海尚信化工装置科技有限公司 A kind of on-line sampling device
CN112284825A (en) * 2020-10-19 2021-01-29 华兰生物工程重庆有限公司 Volatile substance sealing and sampling device capable of being used independently
CN112284825B (en) * 2020-10-19 2023-10-13 华兰生物工程重庆有限公司 Volatile matter sealing sampling equipment capable of being used independently
CN117165416A (en) * 2023-11-03 2023-12-05 苏州雅睿生物技术股份有限公司 Dilution tube, nucleic acid detection device and detection method thereof
CN117165416B (en) * 2023-11-03 2024-01-26 苏州雅睿生物技术股份有限公司 Dilution tube, nucleic acid detection device and detection method thereof
CN118067461A (en) * 2024-04-17 2024-05-24 安丘金山机械制造有限公司 Sampling device for mixed liquid detection
CN118067461B (en) * 2024-04-17 2024-07-23 安丘金山机械制造有限公司 Sampling device for mixed liquid detection

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