Dual pathways pulse generator and implantation type electric stimulation system
Technical field
This utility model relates to implantable medical devices, especially the pulse generator and the implantation type electric stimulation system of the independent adjustable output of the dual pathways.
Background technology
In the prior art, implantation type electric stimulation system and implanted delivery system have obtained application more and more widely as treatment or prophylactic a kind of means.Implantation type electric stimulation system generally includes implantable cardiac electric stimulation (being commonly called as cardiac pacemaker) and implantable nerve electric stimulation, mainly comprises the pulse generator, electrode and the external control device that implant.Wherein, pulse generator is connected with electrode, thereby the burst transmissions that pulse generator produced is arrived electrode, and the pulse signal that pulse generator produces transfers to heart by electrode or electricity irritation is carried out at specific neural position, thereby makes function of human body return to the state of normal operation.
Known implantable nerve electric stimulation mainly comprises pulse generator, electrode, extension wire and external control device usually.Wherein, pulse generator is connected with extension wire, extension wire and then be connected to electrode again, thereby with burst transmissions that pulse generator produced to electrode, so that nerve is carried out electricity irritation.
Implanted dual pathways pulse generator is meant that pulse generator has two-way and stimulates output respectively the brain left and right sides to be stimulated, and realizes therapeutic effect.The stimulus frequency of two passages of dual pathways pulse generator of the prior art must be identical, can't regulate and control respectively, studies show that the brain left and right sides uses the stimulus modelity effect of same frequency undesirable, therefore how to realize dual pathways pulse generator all stimulus parameters (comprising frequency, pulsewidth, amplitude and stimulus modelity) but all independent regulation control, making the neuromodulation of the brain left and right sides reach optimal effectiveness is problem demanding prompt solution.
The utility model content
At the deficiencies in the prior art, the technical problems to be solved in the utility model provides a kind of two passages that can the paired pulses generator and realizes the dual pathways pulse generator and the implantation type electric stimulation system of independent regulation control respectively.
According to technical scheme provided by the utility model, a kind of dual pathways pulse generator, comprise microprocessor module and dual pathways electrical stimulation circuit module, described microprocessor module is used to receive the regulation and control order that vitro program controlled device sends and sends described electrical stimulation circuit module to, and described electrical stimulation circuit module comprises the first boost pulse output channel and the second boost pulse output channel that can distinguish independent regulation and control output.
Preferably, described dual pathways electrical stimulation circuit module is a dual pathways electricity irritation digital-to-analogue hybrid chip.
Preferably, the described regulation and control of independence respectively output comprises frequency, pulsewidth, amplitude, the stimulus modelity of boost pulse.
Preferably, described microprocessor module comprises CPU, memorizer, first communication module;
Described electricity irritation digital-to-analogue hybrid chip comprises second communication module that is connected with described first communication module by communication bus;
The described first boost pulse output channel comprises first passage register-stored module, first passage digital pulse generator, first passage mimic pulse generator, the first passage output control module that is connected successively with described second communication module;
The described second boost pulse output channel comprises second channel register-stored module, second channel digital pulse generator, second channel mimic pulse generator, the second channel output control module that is connected successively with described second communication module.
Preferably, described electricity irritation digital-to-analogue hybrid chip comprises that being used to produce independent regulatable numeral stimulates the digital circuit blocks of adjustment signal output to stimulate adjustment signal to be converted to the analog module of simulation stimulus signal output above-mentioned numeral with being used for;
Described digital circuit blocks comprises described second communication module, first passage register-stored module that is connected with described second communication module and second channel register-stored module, be connected with described first passage register-stored module and be used to produce the first passage assigned frequency, pulsewidth, the first passage digital pulse generator of amplitude and stimulus modelity, be connected with described second channel register-stored module and be used to produce the second channel assigned frequency, pulsewidth, the second channel digital pulse generator of amplitude and stimulus modelity;
Described analog module comprises the first passage mimic pulse generator that is connected with described first passage digital pulse generator, the second channel mimic pulse generator that is connected with described second channel digital pulse generator, the first passage output control module that is connected with described first passage mimic pulse generator, the second channel output control module that is connected with described second channel mimic pulse generator.
Preferably, described specified stimulus modelity is the continued stimulus pattern, bunch sends out stimulus modelity, a kind of in stimulus modelity, motion stimulus modelity, the soft stimulus modelity regularly.
This utility model provides a kind of implantable nerve electric stimulation that comprises aforesaid dual pathways pulse generator.
Preferably, described implantable nerve electric stimulation is a kind of in implanted brain deep electric stimulation, implanted cortex electric stimulation, implanted spinal cord stimulation trial system, implanted sacral nerves electric stimulation or the implanted vagus nerve electric stimulation.
This utility model also provides a kind of implantable cardiac pacing system and implantable cardiac conversion defibrillation system, comprises aforesaid dual pathways pulse generator, and two of the paired pulses generator passages carry out independent regulation control respectively.
Compared with prior art the utility model has the advantages that: because electricity irritation digital-to-analogue hybrid chip of the present utility model comprises the first boost pulse output channel and the second boost pulse output channel that can distinguish independent regulation and control output; make electricity irritation digital-to-analogue hybrid chip to handle to the regulation and control order of the transmission of vitro program controlled device; realize independently regulation and control output through the first boost pulse output channel and the second boost pulse output channel respectively; realize that the doctor can be to the stimulation output (frequency of two passages of dual pathways pulse generator; pulsewidth; amplitude and stimulus modelity) independent adjustable, make the neuromodulation of patient's brain left and right sides reach optimal effectiveness.
Description of drawings
Accompanying drawing 1 is module principle figure of the present utility model;
Accompanying drawing 2 is the module principle figure of pulse generator of the present utility model;
Accompanying drawing 3 is the module principle figure of microprocessor chip of the present utility model and electricity irritation digital-to-analogue hybrid chip.
Wherein:
1, pulse generator; 11, microprocessor chip; 111, first communication module; 12, electricity irritation digital-to-analogue hybrid chip; 121, second communication module; 122, first passage register-stored module; 123, first passage digital pulse generator; 124, first passage mimic pulse generator; 125, first passage output control module; 126, second channel register-stored module; 127, second channel digital pulse generator; 128, second channel mimic pulse generator; 129, second channel output control module; 13, wireless communication module; 14, power supply; 15, the first boost pulse output channel; 16, the second boost pulse output channel; 17, digital circuit blocks; 18, analog module; 2, electrode; 3, vitro program controlled device.
The specific embodiment
Below in conjunction with accompanying drawing this utility model is described in further detail:
With reference to Fig. 1, the independent regulatable implantable nerve electric stimulation of a kind of dual pathways comprises the intravital pulse generator 1 of implant patient, electrode 2, vitro program controlled device 3.Pulse generator 1 is electrically connected with electrode 2, thereby the burst transmissions that pulse generator 1 is produced is arrived electrode 2, so that neuronal target is carried out electricity irritation, reaches the effect of treatment.Vitro program controlled device 3 can communicate by solenoid or wireless communication module with pulse generator 1, thus the various output parameters of regulating impulse generator 1.
With reference to Fig. 2, with the independent regulatable implanted brain of dual pathways deep electric stimulation is example, comprise dual pathways pulse generator 1 in the sternocostal surface subcutaneous tissue of implant patient, implant the electrode 2 that is connected with pulse generator 1 in brain deep, electrical stimulation circuit module, the wireless communication module 13 that pulse generator 1 comprises microprocessor module, be connected with microprocessor module and be the power supply 14 of above-mentioned module for power supply.
Described microprocessor module is used to receive the regulation and control order that vitro program controlled device sends and sends described electrical stimulation circuit module to, and described electrical stimulation circuit module comprises the first boost pulse output channel 15 and the second boost pulse output channel 16 that can distinguish independent regulation and control output.In the present embodiment, described microprocessor module is a microprocessor chip 11, and described dual pathways electrical stimulation circuit module is a dual pathways electricity irritation digital-to-analogue hybrid chip 12.
The output that the first boost pulse output channel 15 and the second boost pulse output channel 16 can independently be regulated and control respectively comprises frequency, pulsewidth, amplitude, the stimulus modelity of boost pulse.The output parameter of the first boost pulse output channel 15 and the second boost pulse output channel 16 can be identical also can be different.
With reference to Fig. 3, described microprocessor module comprises CPU, memorizer, first communication module 111, and described electricity irritation digital-to-analogue hybrid chip 12 comprises second communication module 121 that is connected with described first communication module 111 by communication bus.
The described first boost pulse output channel 15 comprises first passage register-stored module 122, first passage digital pulse generator 123, first passage mimic pulse generator 124, the first passage output control module 125 that is connected successively with described second communication module 121.
The described second boost pulse output channel 16 comprises second channel register-stored module 126, second channel digital pulse generator 127, second channel mimic pulse generator 128, the second channel output control module 129 that is connected successively with described second communication module 121.
First communication module 111 is the SPI sending module in the present embodiment, and second communication module 121 is the SPI receiver module, and the SPI sending module is connected by spi bus with the SPI receiver module and is used for the serial both-way communication.In all the other embodiments, can use other bus communication modes to realize the communication of microprocessor chip 11 and electricity irritation digital-to-analogue hybrid chip 12.
Described electricity irritation digital-to-analogue hybrid chip 12 comprises that being used to produce independent regulatable numeral stimulates the digital circuit blocks 17 of adjustment signal output to stimulate adjustment signal to be converted to the analog module 18 of simulation stimulus signal output above-mentioned numeral with being used for.
Described digital circuit blocks 17 comprises described second communication module 121, the first passage register-stored module 122 and the second channel register-stored module 126 that are connected with described second communication module 121, be connected with described first passage register-stored module 122 and be used to produce the first passage assigned frequency, pulsewidth, the first passage digital pulse generator 123 of amplitude and stimulus modelity, be connected with described second channel register-stored module 126 and be used to produce the second channel assigned frequency, pulsewidth, the second channel digital pulse generator 127 of amplitude and stimulus modelity;
Described analog module 18 comprises the first passage mimic pulse generator 124 that is connected with described first passage digital pulse generator 123, the second channel mimic pulse generator 128 that is connected with described second channel digital pulse generator 127, the first passage output control module 125 that is connected with described first passage mimic pulse generator 124, the second channel output control module 129 that is connected with described second channel mimic pulse generator 128.
Described specified stimulus modelity is the continued stimulus pattern, bunch send out stimulus modelity, a kind of in stimulus modelity, motion stimulus modelity, the soft stimulus modelity regularly.Described timing stimulus modelity is meant the opening and closing state that can have stimulation programs in the interval internal recycle nerve stimulator of program setting, soft stimulus modelity is meant can soft unlatching and soft stopping, promptly allow the value of the slow rising of pulse amplitude when stimulating, when stimulation is closed, allow pulse amplitude slowly to be reduced to 0 up to the permission of program setting when opening.
This utility model provides a kind of implantable nerve electric stimulation that comprises the independent regulatable pulse generator of the aforesaid dual pathways.Different described implantable nerve electric stimulation according to the treatment disease can be a kind of in implanted brain deep electric stimulation, implanted cortex electric stimulation, implanted spinal cord stimulation trial system, implanted sacral nerves electric stimulation or the implanted vagus nerve electric stimulation.
This utility model also provides a kind of implantable cardiac pacing system and implantable cardiac conversion defibrillation system, comprises aforesaid dual pathways pulse generator, and two of the paired pulses generator passages carry out independent regulation control respectively.
But use the pulse generator of the independent independent regulation control of this utility model dual pathways output, the doctor can will regulate and control order input microprocessor chip 11 by wireless communication module 13 by vitro program controlled device and handle, enter second communication module 121 by first communication module 111 through spi bus, be stored in first passage register-stored module 122 and second channel register-stored module 126 then respectively.
First passage register-stored module 122 sends first passage regulation and control order to first passage digital pulse generator 123 and is used for producing the independent regulatable digital adjustment signal output that stimulates, first passage digital pulse generator 123 stimulates adjustment signal to send first passage mimic pulse generator 124 to numeral to be converted to the simulation stimulus signal, and first passage mimic pulse generator 124 will be simulated stimulus signal and be sent 125 outputs of first passage output control module to and stimulate.
Similarly, second channel register-stored module 126 sends second channel regulation and control order to second channel digital pulse generator 127 and is used for producing the independent regulatable digital adjustment signal output that stimulates, second channel digital pulse generator 127 stimulates adjustment signal to send second channel mimic pulse generator 128 to numeral to be converted to the simulation stimulus signal, and second channel mimic pulse generator 128 will be simulated stimulus signal and be sent 129 outputs of second channel output control module to and stimulate.
Compared with prior art; electricity irritation digital-to-analogue hybrid chip 12 of the present utility model comprises the first boost pulse output channel 15 and the second boost pulse output channel 16 that can distinguish independent regulation and control output; make electricity irritation digital-to-analogue hybrid chip 12 to handle to the regulation and control order of the transmission of vitro program controlled device; realize independently regulation and control output through the first boost pulse output channel 15 and the second boost pulse output channel 16 respectively; realize that the doctor can be to the frequency of two passages of dual pathways pulse generator; pulsewidth; stimulation such as amplitude and stimulus modelity output all can independently be regulated and control, and makes the neuromodulation of patient's brain left and right sides reach optimal effectiveness.
This utility model also can have other various embodiments; under the situation that does not deviate from this utility model spirit and essence; those skilled in the art can make various corresponding changes and distortion according to this utility model, but these corresponding changes and distortion all should belong to the scope of claim protection of the present utility model.