CN1970069B - Chinese medicinal pill for treating coronary heart disease - Google Patents
Chinese medicinal pill for treating coronary heart disease Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal pill preparation for treating coronary disease which is prepared from 30 kinds of Chinese herbs including astragalus root, prepared rhizome of rehmannia, Chinese angelica root, root of red rooted saliva, Ligusticum wallichii, Loranthus mulberry mistletoe, pericarpium trichosanthis, corydalis tuber, root of herbaceous peony, grassleaved sweetflag rhizome, spatholobus stem, grassleaved sweetflag rhizome, black sesame seeds, dodder seed, white atractylodes rhizome, curcuma aromatica, prepared fleece flower root, epimeddium, spine date seed, schisandrafruit, donkey-hide gelatin, ganoderma lucidum, poria cocos, burred tuber, zedoary, ophiopogon root, oyster shell, pilose asiabell root, sandalwood and licorice root through steps of disintegrating, charging bee honey and modulating.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relating to a kind of is the pharmaceutical composition of raw material treatment coronary heart disease with the Chinese herbal medicine.
Technical background
Heart is a most important organ on the human body, when the beat function of finishing pump blood～of heart to each organ of whole body, when tissue is carried nutrient substance and fresh blood, life could be survived, life depends on heartbeat, yet, in the life evolutionary process, getting in touch between the coronary artery of heart and blood supply system but is quite fragile.In case blood supply system forms coronary artery medicated porridge myocardial infarction, will cause partial blockage in the lumen of vessels, myocardial ischemia, angina pectoris, to such an extent as to threaten people's life.At present, China's evidence of coronary heart diseases sharply rises, and age of onset is downward trend day by day.Coronary heart disease has three kinds of methods at present: Drug therapy, interventional therapy and surgery bypass surgery, and interventional therapy and bypass surgery are generically and collectively referred to as transmyocardial revascularization again.Surgical method is a danger close, but and pharmacotherapy is difficult to radical cure.The patent of a kind of application number 200410060497 " a kind of medicine pill for the treatment of coronary heart disease " was disclosed on the Chinese patent communique on March 8th, 2006, it adopts Radix Stephaniae Tetrandrae, the Radix Astragali, Cortex Moutan, Pheretima, Rhizoma Alismatis, Radix Puerariae, Radix Salviae Miltiorrhizae, Fructus Crataegi, the Radix Polygoni Multiflori, Rhizoma Chuanxiong, it has the advantage that curative effect is reliable, toxic and side effects is little, and curative effect is long but smelting is healed.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides the medicine pill of the treatment coronary heart disease that a kind of instant effect, short treating period have no side effect.
The object of the present invention is achieved like this: a kind of medicine pill for the treatment of coronary heart disease according to each drug component of percentage by weight is:
The Radix Astragali 7%～9.26%, Radix Rehmanniae Preparata 4%～6.84%, Radix Angelicae Sinensis 3%～3.5%, Radix Salviae Miltiorrhizae 3%～3.5%, Rhizoma Chuanxiong 3%～3.5%, Herba Taxilli 3%～3.5%, Fructus Trichosanthis 3%～3.5%, Rhizoma Corydalis 3%～3.5%, Radix Paeoniae 3%～3.5%, Rhizoma Anemones Altaicae 3%～3.5%, Caulis Spatholobi 3%～3.5%, Rhizoma Polygonati 3%～3.5%, Semen Sesami Nigrum 3%～3.5%, Semen Cuscutae 3%～3.5%, the Rhizoma Atractylodis Macrocephalae 3%～3.5%, Radix Curcumae 2.5%～2.92%, Herba Epimedii 2.5%～2.92%, Fructus Schisandrae Chinensis 2.5%～2.92%, Radix Polygoni Multiflori Preparata 2.5%～2.92%, Semen Ziziphi Spinosae 2.5%～2.92%, Colla Corii Asini 2.5%～2.92%, Ganoderma 2.5%～2.92%, Poria 2.5%～2.92%, rhizoma sparganic 2.5%～2.92%, Rhizoma Curcumae 2.5%～2.92%, Radix Ophiopogonis 3%～5.0%, Concha Ostreae 3%～5.0%, Radix Codonopsis 3%～5.0%, Lignum Santali Albi 2.28%～2.6%, Radix Glycyrrhizae 2.28%～2.6%.
Optimal drug composition weight percentage ratio of the present invention is:
The Radix Astragali 8.13%, Radix Rehmanniae Preparata 5.42%, Radix Angelicae Sinensis 3.25%, Radix Salviae Miltiorrhizae 3.25%, Rhizoma Chuanxiong 3.25%, Herba Taxilli 3.25%, Fructus Trichosanthis 3.25%, Rhizoma Corydalis 3.25%, Radix Paeoniae 3.25%, Rhizoma Anemones Altaicae 3.25%, Caulis Spatholobi 3.25%, Semen Sesami Nigrum 3.25%, Rhizoma Polygonati 3.25%, Semen Cuscutae 3.25%, the Rhizoma Atractylodis Macrocephalae 3.25%, Radix Curcumae 2.71%, Herba Epimedii 2.71%, Fructus Schisandrae Chinensis 2.71%, Radix Polygoni Multiflori Preparata 2.71%, Semen Ziziphi Spinosae 2.71%, Colla Corii Asini 2.71%, Ganoderma 2.71%, Poria 2.71%, rhizoma sparganic 2.71%, Rhizoma Curcumae 2.71%, Radix Ophiopogonis 4.065%, Concha Ostreae 4.065%, Radix Codonopsis 4.065%, Lignum Santali Albi 2.44%, Radix Glycyrrhizae 2.44%.
At first, the present invention earlier adds vinegar with Rhizoma Corydalis according to this medical material gross weight 5%, adds that to propagandize the back hotly standby; Fructus Schisandrae Chinensis is chosen from the northeast medical material; Semen Ziziphi Spinosae adopts parch; Semen Cuscutae is selected for use to steam; The Rhizoma Atractylodis Macrocephalae is fried to jaundice, and is standby; Radix Glycyrrhizae forms by processed with honey, promptly carries out parch earlier, adds Mel then and dilutes, and is until the medical material adhesion, standby.
Above-mentioned 30 kinds of Chinese herbal medicine were ground into the fine powder of 100 mesh sieves jointly, modulated honeyed pill at 1: 1 according to mixed powder and Mel.When taking, 2-3 time/day, 9g/ time, 15 is a course of treatment.
The present invention is fully according to Chinese medical theory, utilization: the blood-nourishing blood-generating of the Radix Astragali, Radix Angelicae Sinensis, set upright and invigorate vital energy and reinforce the heart to help the blood vessels operation, the liver protecting is arranged, prevent the effect that liver glycogen reduces; Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling have the effect of coronary artery dilator and increase LBF amount, angina pectoris spasmolytic, the whole blood viscosity of improving, blood pressure lowering; Herba Taxilli, Fructus Trichosanthis energy coronary artery dilator blood flow increasing have protective effect, can reduce physical demands myocardial ischemia; Radix Curcumae has the effect of alleviating to the formation and the lipidosis of aorta and crown endarterium speckle; Use the Rhizoma Corydalis regulating QI to relieve pain during stagnation of QI and blood thoracic obstruction bitterly, the bile secretion of enhancing is arranged, promote gallbladder to shrink, quicken the bile excretion effect; Radix Paeoniae Alba claims the Radix Paeoniae Alba again, and yin fluid astringing benefit blood, nourishing blood to suppress the hyperactive liver are arranged; Herba Epimedii also claims Herba Epimedii, have the kidney invigorating gas help heart-yang, to declare logical breast sun, make that YIN-cold expectorant is turbid to be dissipated, deep and weak pulse yang deficiency is improved the effect of myocardial ischemia; Contain multiple steroid saponin Radix Ophiopogonis, can control dryness of the lung dry cough, deficiency of YIN dryness of the intestine, can adjust blood glucose and antibiotic, have the effect of the relieving restlessness that clears away heart-fire, nourishing YIN and moistening the lung, reinforcing stomach reg fluid; Fructus Schisandrae Chinensis adopts the medical material in northeast, the enzyme of falling hepatoprotective, palpitation and insomnia are arranged, astringe the lung promote the production of body fluid, the effect of YIN nourishing astringing QI; The Rhizoma Anemones Altaicae circulation of qi promoting of having one's ideas straightened out makes the capable then blood of gas capable, has the invigorating the spleen and replenishing QI nourishing blood to promote the production of body fluid; Radix Codonopsis regulating QI anemia void, tonification vigour, can improve myocardial oxygen delivery and heart tonifying; The Radix Polygoni Multiflori Preparata that the present invention uses be with Radix Polygoni Multiflori and Semen sojae atricolor with boiling the drying in the sun Radix Polygoni Multiflori afterwards, be invigorating the liver and kidney simply, benefiting essence-blood, the good medicine that nourishes heart and allay excitement, but its vessel softening, cholesterol reducing, triglyceride; Caulis Spatholobi contains the catechol tannin, and having enriches blood invigorates blood circulation relaxing muscles and tendons and activating QI and blood in the collateral; Semen Sesami Nigrum has invigorating the liver and kidney, beneficial menses, energy adjust blood pressure, lung moistening; The effect that the Semen Ziziphi Spinosae of parch nourishes blood yin fluid astringing, calms the nerves and feel at ease; Rhizoma Polygonati has lung moistening YIN nourishing, invigorating the spleen and replenishing QI, the kidney invigorating and essence nourishing; Concha Ostreae has suppressing the hyperactive liver and subsiding YANG, astringent or styptic treatment for spontaneous sweating convergence, but the treating the liver splenomegaly; Colla Corii Asini contains several amino acids, can improve the whole body function, improves calcium balance in the body, promotes hemopoietic, promotes calcium absorption, helps retaining of calcium in the serum, improves the myocardial nutrition obstacle; Ganoderma has tonification strong, and protecting liver and detoxication promotes hepatic injury to recover, and improves immunity, transaminase lowering; The Poria promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach; Rhizoma sparganic, Rhizoma Curcumae blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain; The resinous glycoside of Semen Cuscutae, saccharide, have tonifying liver and kidney tonifying, support make eye bright, spleen reinforcing antidiarrheal, be applicable to insufficiency of the spleen loose stool; Radix Rehmanniae Preparata claims Radix Rehmanniae Preparata again, has the YIN nourishing of enriching blood, vital essence replenishing and marrow benifiting, is used for waist soreness, feels dizzy Hiccough and deaf, all cards through anemia void such as early whitening of beard and hair; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and replenishing QI, the spleen strengthening and damp drying, and the liver protecting is arranged, and prevents the effect that liver glycogen reduces; Lignum Santali Albi is the heartwood of Santalaceae plant Lignum Santali Albi trunk, can regulate the flow of vital energy dispersing cold for relieving pain, blood-activating and qi-promoting; Radix Glycyrrhizae contains the triterpenoid saponin glycyrrhizic acid, can control weakness of the spleen and stomach, and the Radix Glycyrrhizae of processed with honey has moist tonification, mends three warmers vigour, relaxes the property of medicine, and can help heart-yang, qualcomm meridian, sharp vim and vigour, blood circulation promoting regulates qi, inspiration QI-blood circulation.
The present invention is according to Chinese medical theory, make full use of the said medicine combination effect of supplementing and complementing each other, reach warming YANG and invigorating QI jointly, the multiple arteries and veins of invigorating blood circulation, blood circulation promoting regulates qi, disperse blood stasis and dredge collateral, a surname's numbness allay excitement, promote QI-blood circulation and the blood stasis removing of enriching blood, and greatly improves the efficient of curing coronary heart disease.
Compared with the prior art, the present invention is simple, the short treating period of preparation technology not only, and pure Chinese medicinal preparation, has no side effect.
The specific embodiment
Below in conjunction with embodiment the present invention is further detailed.
From beginning in 1980, the present invention goes on foot therapy according to the traditional Chinese medical science three of radical cure coronary heart disease: the method for " controlling asthenia of cholic qi increase bile earlier is that heart provides enough nutrition, the coronary heart disease that the treatment asthenia of qi and blood causes deficiency of heart-blood to be given birth to the QI and blood deficiency that helps fortuneization, conditioning asthenia of cholic qi to cause ", adopt a step wherein in the three step therapies, with " tonify deficiency 'Tongluowan ' " thousands of routine patients are carried out the treatment of coronary heart disease, by clinical trial certificate, total effective rate is 96%.
Case 1
The Wang, woman, 51 years old.
Be coronary heart disease at Linqu County, Shandong Province hospital diagnosis in 98 years, invalid through multi-treatment.Recently patient feels again sensation of oppression over the chest with shortness of breath, insomnia and dreamful sleep, and there is sense of heaviness at the back, through the check electrocardiogram, finds that the ST section moves down, and the T ripple is low flat, is diagnosed as coronary heart disease and increases the weight of.Through taking the present invention's " tonify deficiency 'Tongluowan ' " after 1 course of treatment, sensation of oppression over the chest with shortness of breath, insomnia and dreamful sleep, back sense of heaviness transference cure continued to take 2 courses of treatment, and every index is normal.
Case 2
Grandson, the man, 43 years old, surplus the combined valvular disease that has a heart disease 16 year.Heart failure often appears in patient's general edema, liver spleen silght enlargement repeatedly over nearly 3 years.By the agency of is treated to the court, takes the present invention's " tonify deficiency 'Tongluowan ' " after 1 course of treatment according to three step therapies, and anasarca disappears, and it is normal that the liver spleen is tending towards; After continuing to take 2 courses of treatment, every index is normal, and patient can normally work, live.
Case 3
Liu, man, workman.In March, 97 is during hospital admission, and heart rate reaches 30-45 time/minute, chest distress is arranged, suppress bloated phenomenon before the heart, is diagnosed as DCM (dilated cardiomyopathy), is equipped with cardiac pacemaker, no viability.After taking the present invention's " tonify deficiency 'Tongluowan ' " 1 half course of treatment according to three step therapies, chest distress obviously improves, and heart rate becomes 42-58 time/minute.Continued to take 2 courses of treatment after check, heart obviously bounces back, and each index is tending towards normally, and life can normally be taken care of oneself, work as usual.
ProductName of the present invention adopts " tonify deficiency 'Tongluowan ' ", and it is the Chinese medicine composition in a step wherein in three step of the traditional Chinese medical science therapy radical cure coronary heart disease, in order to detect performance of the present invention, has carried out following experiment:
One, toxicity test
" tonify deficiency 'Tongluowan ' " of the present invention in order to detect property of medicine is chosen 6 of healthy home mouse, and every about 40 grammes per square metres are filled out hello " tonify deficiency 'Tongluowan ' " of the present invention according to the maximum tolerance pharmaceutical quantities 80 gram/kilograms of home mouse.After 7 days, all none death of home mouse.Through anatomic observation, through anatomic observation hemogram, liver function, each internal organs official tissue morphology does not have any unusual, illustrates that the present invention is safe in utilization.
Two, clinical experiment
With reference to the related standards of International Society of Cardiology and World Health Organization (WHO), carry out clinical experiment, method is as follows:
134 of picked at random suffer from coronary disease disease patient and divide into groups, and are test group, each 67 example of matched group;
Treatment foundation: angina pectoris, stagnation of heart-blood, the thoracic obstruction, blood supply insufficiency;
Therapeutic Method: matched group is taken the XUESAITONG drop pill, every ball 9g, 1/time, 3 times/day; Test group is taken the present invention's " tonify deficiency 'Tongluowan ' ", every ball 9g, and 3 times/day, 1 ball/time.Testing period was 4 weeks.
Reference index: blood, urine, the excrement of generally experiencing project, routine; Electrocardiogram, liver function, renal function.
Observational technique: each angina pectoris attacks situation, the record of the various situations of change of the electrocardiogram before and after the medication, pulse, health, record is once weekly.
The treatment standard: recovery from illness, clinical symptom disappearance after the course of treatment, does not not repeatedly rebound; Invalid, do not see change, it is little for effect.
1, the angina pectoris curative effect is relatively:
Table 1, two groups of angina pectoris curative effects relatively (%, n=67)
| Group | Produce effects | Effectively | Invalid | Effective percentage |
| Test group (67) | 26(38.8) | 35(52.2) | 6(8.9) | 91.05％ |
| Matched group (67) | 18(26.8) | 38(56.7) | 11(16.4) | 85.58％ |
The result shows: the test group effective percentage obviously is better than matched group.
2, pain attack times uncomfortable in chest compares before and after the treatment:
Pain attack times comparison uncomfortable in chest before and after the table 2 liang group treatment (%, n=67)
| Group | Disappearance/example (%) | Improvement/example (%) | Constant/example (%) | Increase the weight of/example (%) | Fall and add up | P |
| Test group (67) | 20(29.9) | 43(64.2) | 4(6.0) | 0(0.0) | -2.348 | 0.019 |
| Test group (67) | 13(19.4) | 40(59.7) | 14(20.9) | 0(0.0) |
The result shows: treatment back pain attack times test group uncomfortable in chest is better than matched group.
(P＜0.01)。
3, the tcm syndrome total mark is relatively:
Specify according to " new Chinese medicine treatment angina pectoris (thoracic obstruction) clinical research guideline ".Wherein tcm syndrome total effects criterion judges that according to the integration therapeutic index tcm syndrome total effects is a produce effects: therapeutic index≤0.33, effectively: 0.33＜therapeutic index＜0.67, invalid: 0.67＜therapeutic index≤1.00, increase the weight of: therapeutic index 〉=1.00
Table 3 liang group tcm syndrome total mark is (%, n=67) relatively
The result shows: two groups of treatment back tcm syndrome total marks all descend (P＜0.01), and the tcm syndrome total mark of treatment 2 all backs test group is better than matched group (P＜0.01).
(4) onset time is relatively:
Table 4 liang group onset time comparison (P, n=67)
| Group | X±S | Median | Minima | Maximum |
| Test group | 5.5±3.5 | 5 | 1 | 15 |
| Matched group | 9.8±5.9 | 8 | 2 | 25 |
The result shows: there were significant differences (P＜0.01) between two groups of onset times groups, and test group is better than matched group.
Show from above-mentioned clinical test results: the present invention's " tonify deficiency 'Tongluowan ' " is to angina pectoris total effective rate 91.05%, can obviously improve the various symptoms of angina pectoris, total effective rate 86.6% to tcm symptom, illustrate that the present invention to its antithrombotic, anticoagulant, blood vessel dilating, improvement blood supply coronarius, can treat angina pectoris effectively; Onset time of the present invention is short, and " tonify deficiency 'Tongluowan ' " easier absorption has been described, onset is rapid, drug effect is had an effect soon, and the control angina pectoris is rapid.
Embodiment 1
At first the percentage by weight according to pharmaceutical composition takes by weighing respectively
Radix Astragali 300g, Radix Rehmanniae Preparata 200g, Radix Angelicae Sinensis 120g, Radix Salviae Miltiorrhizae 120g, Rhizoma Chuanxiong 120g, Herba Taxilli 120g, Fructus Trichosanthis 120g, Rhizoma Corydalis 120g, Radix Paeoniae 120g, Rhizoma Polygonati 120g, Caulis Spatholobi 120g, Rhizoma Anemones Altaicae 120g, Semen Sesami Nigrum 120g, Semen Cuscutae 120g, Rhizoma Atractylodis Macrocephalae 120g, Radix Curcumae 100g, Radix Polygoni Multiflori Preparata 100g, Herba Epimedii 100g, Semen Ziziphi Spinosae 100g, Fructus Schisandrae Chinensis 100g, Colla Corii Asini 100g, Ganoderma 100g, Poria 100g, rhizoma sparganic 100g, Rhizoma Curcumae 100g, Radix Ophiopogonis 150g, Concha Ostreae 150g, Radix Codonopsis 150g, Lignum Santali Albi 90g, Radix Glycyrrhizae 90g, wherein Rhizoma Corydalis forms according to the 5% interpolation vinegar heating parch of this medical material gross weight; Fructus Schisandrae Chinensis is selected from the northeast medical material; The Semen Ziziphi Spinosae parch is good; Semen Cuscutae steamed; The Rhizoma Atractylodis Macrocephalae is fried to jaundice, and is standby; Radix Glycyrrhizae forms by processed with honey; Then above-mentioned standby 30 kinds of good Chinese herbal medicine were ground into jointly the fine powder of 100 mesh sieves, modulated honeyed pill at 1: 1 according to mixed-powder and Mel.
Embodiment 2
At first the percentage by weight according to pharmaceutical composition takes by weighing down 30 kinds of medium-height grass materials of example respectively;
Radix Astragali 35g, Radix Rehmanniae Preparata 35g, Radix Angelicae Sinensis 15g, Radix Salviae Miltiorrhizae 15g, Rhizoma Chuanxiong 15g, Herba Taxilli 15g, Fructus Trichosanthis 15g, Rhizoma Corydalis 15g, Radix Paeoniae 15g, Rhizoma Polygonati 15g, Caulis Spatholobi 15g, Rhizoma Anemones Altaicae 15g, Semen Sesami Nigrum 15g, Semen Cuscutae 15g, Rhizoma Atractylodis Macrocephalae 15g, Radix Curcumae 14.6g, Radix Polygoni Multiflori Preparata 14.6g, Herba Epimedii 14.6g, Semen Ziziphi Spinosae 14.6g, Fructus Schisandrae Chinensis 14.6g, Colla Corii Asini 14.6g, Ganoderma 14.6g, Poria 14.6g, rhizoma sparganic 14.6g, Rhizoma Curcumae 14.6g, Radix Ophiopogonis 21.5g, Concha Ostreae 21.5g, Radix Codonopsis 21.5g, Lignum Santali Albi 12g, Radix Glycyrrhizae 12g, wherein Rhizoma Corydalis is to add vinegar heating parch according to 5% of own wt to form; Fructus Schisandrae Chinensis is selected from the northeast medical material; The Semen Ziziphi Spinosae parch is good; Semen Cuscutae steams; The Rhizoma Atractylodis Macrocephalae is fried to jaundice, and is standby; Radix Glycyrrhizae forms by processed with honey; Then above-mentioned standby 30 kinds of good Chinese herbal medicine were ground into jointly the fine powder of 100 mesh sieves, modulated honeyed pill at 1: 1 according to mixed-powder and Mel.
Embodiment 3
At first the percentage by weight according to pharmaceutical composition takes by weighing down 30 kinds of medium-height grass materials of example respectively;
Radix Astragali 46g, Radix Rehmanniae Preparata 20g, Radix Angelicae Sinensis 17.4g, Radix Salviae Miltiorrhizae 17.4g, Rhizoma Chuanxiong 17.4g, Herba Taxilli 17.4g, Fructus Trichosanthis 17.4g, Rhizoma Corydalis 17.4g, Radix Paeoniae 17.4g, Rhizoma Polygonati 17.4g, Caulis Spatholobi 17.4g, Rhizoma Anemones Altaicae 17.4g, Semen Sesami Nigrum 17.4g, Semen Cuscutae 17.4g, Rhizoma Atractylodis Macrocephalae 17.4g, Radix Curcumae 12.5g, Radix Polygoni Multiflori Preparata 12.5g, Herba Epimedii 12.5g, Semen Ziziphi Spinosae 12.5g, Fructus Schisandrae Chinensis 12.5g, Colla Corii Asini 12.5g, Ganoderma 12.5g, Poria 12.5g, rhizoma sparganic 12.5g, Rhizoma Curcumae 12.5g, Radix Ophiopogonis 20g, Concha Ostreae 20g, Radix Codonopsis 20g, Lignum Santali Albi 11.4g, Radix Glycyrrhizae 11.4g, wherein Rhizoma Corydalis is to add vinegar heating parch according to 5% of own wt to form; Fructus Schisandrae Chinensis is selected from the northeast medical material; The Semen Ziziphi Spinosae parch is good; Semen Cuscutae steams; The Rhizoma Atractylodis Macrocephalae is fried to jaundice, and is standby; Radix Glycyrrhizae forms by processed with honey; Then above-mentioned standby 30 kinds of good Chinese herbal medicine were ground into jointly the fine powder of 100 mesh sieves, modulated honeyed pill at 1: 1 according to mixed-powder and Mel.
Claims (1)
1, a kind of medicine pill for the treatment of coronary heart disease, make by following each drug component:
The Radix Astragali 7%～9.26%, Radix Rehmanniae Preparata 4%～6.84%, Radix Angelicae Sinensis 3%～3.5%, Radix Salviae Miltiorrhizae 3%～3.5%, Rhizoma Chuanxiong 3%～3.5%, Herba Taxilli 3%～3.5%, Fructus Trichosanthis 3%～3.5%, Rhizoma Corydalis 3%～3.5%, Radix Paeoniae 3%～3.5%, Rhizoma Anemones Altaicae 3%～3.5%, Caulis Spatholobi 3%～3.5%, Rhizoma Polygonati 3%～3.5%, Semen Sesami Nigrum 3%～3.5%, Semen Cuscutae 3%～3.5%, the Rhizoma Atractylodis Macrocephalae 3%～3.5%, Radix Curcumae 2.5%～2.92%, Herba Epimedii 2.5%～2.92%, Fructus Schisandrae Chinensis 2.5%～2.92%, Radix Polygoni Multiflori Preparata 2.5%～2.92%, Semen Ziziphi Spinosae 2.5%～2.92%, Colla Corii Asini 2.5%～2.92%, Ganoderma 2.5%～2.92%, Poria 2.5%～2.92%, rhizoma sparganic 2.5%～2.92%, Rhizoma Curcumae 2.5%～2.92%, Radix Ophiopogonis 3%～5.0%, Concha Ostreae 3%～5.0%, Radix Codonopsis 3%～5.0%, Lignum Santali Albi 2.28%～2.6%, Radix Glycyrrhizae 2.28%～2.6%;
Earlier Rhizoma Corydalis is added vinegar according to 5% of this medical material gross weight, add that to propagandize the back hotly standby; Fructus Schisandrae Chinensis adopts the medical material in northeast; Semen Ziziphi Spinosae adopts parch; Semen Cuscutae is selected for use to steam; The Rhizoma Atractylodis Macrocephalae is fried to jaundice, and is standby; Radix Glycyrrhizae forms by sweet moxibustion, promptly carries out parch earlier, adds Mel then and dilutes, and is until the medical material adhesion, standby;
Above-mentioned 30 kinds of Chinese herbal medicine were ground into the fine powder of 100 mesh sieves jointly, modulated honeyed pill at 1: 1 according to mixed powder and Mel.
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| CN102670956B (en) * | 2011-03-17 | 2014-11-19 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Application of Chinese medicinal composition to preparation of anti-myocardial cell apoptosis and/or anti-myocardial cell apoptosis related disease drug |
| CN102205049B (en) * | 2011-05-11 | 2012-07-04 | 杨雪珍 | Medicinal composition for treating premature beat |
| CN102406754B (en) * | 2011-11-18 | 2013-03-20 | 杨蕊 | Chinese medicinal composition for treating chronic heart failure |
| CN102600438B (en) * | 2012-04-21 | 2014-04-23 | 韩合旭 | Medicament for treating diabetes mellitus, hypertension, hyperlipidemia and coronary heart disease |
| CN102641420B (en) * | 2012-05-15 | 2013-08-21 | 沈长发 | Pharmaceutical composition for treating coronary heart disease |
| CN102935195B (en) * | 2012-12-08 | 2014-03-26 | 王颖翠 | Traditional Chinese medicine composition for treating coronary heart disease as well as preparation method and application thereof |
| CN103611088B (en) * | 2013-12-08 | 2015-08-05 | 朱英 | A kind of medicine for the treatment of coronary heart disease and preparation method thereof |
| CN104127672A (en) * | 2014-08-01 | 2014-11-05 | 范广慈 | Traditional Chinese medicine formula for treating cardiomyopathy |
| CN104547939A (en) * | 2015-01-15 | 2015-04-29 | 安乐红 | Traditional Chinese medicine preparation for treating premature beat |
| CN105194298A (en) * | 2015-11-10 | 2015-12-30 | 叶建斌 | A traditional Chinese medicine oral liquid for treating coronary heart disease and its preparation method |
| CN105853847A (en) * | 2016-05-25 | 2016-08-17 | 上海市中医医院 | Traditional Chinese medicine composition for treating triple-vessel disease of coronary heart disease and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (en) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | Medicinal composition for restoring cardiac collaterals and its application |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (en) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | Medicinal composition for restoring cardiac collaterals and its application |
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