CN102600438B - Medicament for treating diabetes mellitus, hypertension, hyperlipidemia and coronary heart disease - Google Patents

Abstract

The invention discloses a medicament for treating diabetes mellitus, hypertension, hyperlipidemia and coronary heart disease. The medicament comprises the following components in parts by weight: 30 parts of dried rehmannia root, 10 parts of radix ophiopogonis, 20 parts of root of Chinese trichosanthes, 30 parts of root of kudzu vine, 10 parts of epimedium, 30 parts of astragalus root, 20 parts of yams, 25 parts of root of bidentate achyranthes, 15 parts of uncaria, 15 parts of sea clam shells, 10 parts of asafetida, 10 parts of pipe fish, 25 parts of polygonum multiflorum, 10 parts of parasitic loranthus, 10 parts of radix curcumae, 20 parts of root of red-rooted salvia, 10 parts of pericarpium trichosanthis, 15 parts of seed of Chinese dodder and 15 parts of Szechuan lovage rhizome.

Description

The medicine for the treatment of diabetes, hypertension, hyperlipidemia and coronary heart disease

Technical field

The present invention relates to a kind of medicine for the treatment of diabetes, hypertension, hyperlipidemia and coronary heart disease.

Background technology

Diabetes are by inherited genetic factors, immunologic function disorder, infected by microbes and toxin thereof, free radical toxin, the various virulence factors of Nervous and Mental Factors etc. act on body and cause hypoinsulinism, insulin resistant etc. and the sugar that causes, protein, fat, a series of metabolism disorder syndromes such as power and water Xie Zhi, take hyperglycemia clinically as main feature, can there is polyuria in model case, polydipsia, polyphagia, the performance such as become thin, i.e. " three-many-one-little " symptom, diabetes (blood glucose) cause complication once control bad meeting, cause kidney, eye, the exhaustion pathological changes at the positions such as foot, and cannot cure.

Hypertension (hypertensive disease) is a kind ofly to take arteriotony and continue to raise be often to cause the chronic disease of main manifestations the pathological changes of the vitals such as the heart, brain, kidney and to occur corresponding consequence.Lipid metabolism or running make one or more lipids of blood plasma higher than being normally called hyperlipidemia extremely.Hyperlipidemia is a kind of systemic disease, refers to that T-CHOL in blood (TC) and/or triglyceride (TG) are too high or HDL-C (HDL-C) is too low, and modern medicine is referred to as dyslipidemia.Lipid is insoluble or be slightly soluble in water, must with lipoprotein form, exist with protein bound, and therefore, hyperlipidemia is conventionally also referred to as hyperlipoproteinemia.The cause of disease of hyperlipidemia, can be divided into two large class, i.e. In Patients With Primary Hyperlipoidemia and Secondary cases hyperlipidemias substantially.

In Patients With Primary Hyperlipoidemia

1, inherited genetic factors.Heredity can cause hyperlipemia by number of mechanisms, some may occur on cellular level, main manifestations is the defect (as the defect of lipoprotein lipase or shortage) of some enzyme in cell surface lipoprotein receptor volume defect and cell, also can occur on the molecule of lipoprotein or apolipoprotein, how because genetic flaw causes.

2, dietary factor.Dietary factor effect more complicated, it is closely-related with dietary factor that patients with hyperlipoproteinemia has sizable ratio in being in hospital.

3, clinical experiment shows: the normocyte in blood, colloid particle etc. are electronegative, between them, mutually repels, and maintains a certain distance, and the aging erythrocyte of pathological changes is because electronics is fought for, positively charged, due to positive negative suction, that red blood cell condensation is agglomerating, cause hyperlipidemia.

Secondary cases hyperlipidemia

Secondary cases hyperlipidemia is that these diseases comprise: diabetes, hepatopathy, thyroid disease, kidney disease, pancreas, obesity, glycogen storage disease, gout, bronzed disease, Cushing's syndrome, abnormal globulin mass formed by blood stasis etc. due to primary disease institute causer in the middle of other.

1, diabetes and hyperlipoproteinemia.In human body, between carbohydrate metabolism and lipid metabolism, there is close contacting, clinical research discovery, approximately 40% diabetics can secondary cause hyperlipemia.

2, hepatopathy and hyperlipoproteinemia.Modern medicine study data confirms, many materials comprise that lipid and lipoprotein etc. processes, produces and decompose at liver, drains.Once liver has pathological changes, lipid and lipoprotein metabolism also will get muddled.

3, obesity and hyperlipoproteinemia.Local clinic study data shows, the Chang Jifa of obesity causes blood triglyceride increased content, and some patients were first cholesterolemia content also may increase, and main manifestations is iv type hyperlipoproteinemia mostly, is secondly iib type hyperlipoproteinemia.

Summary of the invention

The object of this invention is to provide a kind of medicine for the treatment of diabetes, hypertension, hyperlipidemia and coronary heart disease.

The present invention is comprised of the component of following weight parts:

30 parts of Radix Rehmanniae, 10 parts of Radix Ophiopogonis, 20 parts of Radix Trichosanthis, 30 parts of Radix Puerariaes, 15 parts of Herba Epimedii, 30 parts of Radix Astragali, 20 parts of Rhizoma Dioscoreaes, 25 parts of Radix Achyranthis Bidentataes, 15 parts of Ramulus Uncariae Cum Uncis, 15 parts of Concha Meretricis seu Cyclinaes, 10 parts of Resina Ferulaes, 10 parts of Solenognathus, 25 parts of Radix Polygoni Multiflori, 10 parts of Herba Taxillis, 10 parts of Radix Curcumaes, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Pericarpium Trichosanthiss, 15 parts of Semen Cuscutae, 15 parts of Rhizoma Chuanxiongs.

The present invention is with Radix Rehmanniae, Radix Ophiopogonis, Radix Trichosanthis, Radix Puerariae, Herba Epimedii invigorating the spleen and replenishing QI, YIN nourishing and the production of body fluid promoting, the yang invigorating of quenching one's thirst; With Radix Astragali, Rhizoma Dioscoreae invigorating the spleen and benefiting QI; With Radix Achyranthis Bidentatae, Ramulus Uncariae Cum Uncis, Concha Meretricis seu Cyclinae, Resina Ferulae, the steady blood pressure of Solenognathus; With Radix Polygoni Multiflori, Herba Taxilli and Radix Curcumae purify the blood fat melting and thrombolytic; With the multiple arteries and veins of Radix Salviae Miltiorrhizae, Pericarpium Trichosanthis, Semen Cuscutae and Rhizoma Chuanxiong dredging collateral, kidney nourishing water, contains edema with the liver involved, and heart-fire, falls in strengthening the spleen soil, except scorching, and Ji blood.

Beneficial effect of the present invention:

The present invention has invigorating the spleen and replenishing QI, phencyclidine, moisturizes, tonifying the kidney to consolidate the essence, promoting the production of body fluid to quench thirst, eliminating phlegm to promote tissue regeneration, supplementing QI and nourishing YIN, blood circulation promoting and blood stasis dispelling, multiple arteries and veins, blood nourishing acupuncture-stimulating, invigorating the spleen and benefiting QI, clearing away heat-damp and promoting diuresis and consolidate the effect of righting nourish heart.The effect with treatment diabetes, hypertension, hyperlipidemia and coronary heart disease.

The specific embodiment

The present embodiment is comprised of the component of following weight parts:

Radix Rehmanniae 30g, Radix Ophiopogonis 10g, Radix Trichosanthis 20g, Radix Puerariae 30g, Herba Epimedii 15g, Radix Astragali 30g, Rhizoma Dioscoreae 20g, Radix Achyranthis Bidentatae 25g, Ramulus Uncariae Cum Uncis 15g, Concha Meretricis seu Cyclinae 15g, Resina Ferulae 10g, Solenognathus 10g, Radix Polygoni Multiflori 25g, Herba Taxilli 10g, Radix Curcumae 10g, Radix Salviae Miltiorrhizae 20g, Pericarpium Trichosanthis 10g, Semen Cuscutae 15g, Rhizoma Chuanxiong 15g.According to above-mentioned formula, make decoction, every milliliter contained 1g, every day 3 times, each serving 50～80ml.

Treatment diabetes case: Liu, female, 53 years old.Suffer from diabetes 3 years, one takes insoral.Empty stomach glucose in urine (+++), blood glucose 238mg/dl (13.3mmol/L), blood glucose 327mg/dl (18.2mmol/L) after food.Thirsty polydipsia, urine amount is many, the soreness of waist, spirit is tired, and large dry stool is dizzy nervous, easily perspires, very scorching, deficiency in origin and excess in superficiality.Take the present invention's medicine 35 days, thirstyly stop, glucose in urine is normal, and spirit takes a turn for the better.

Treatment hypertension, hyperlipidemia and coronary heart disease case: Zhang, man, 65 years old, suffer from hypertension, hyperlipidemia and coronary heart disease simultaneously, take Western medicine blood pressure lowering, eat less greasy food blood fat reducing, and then avoid the outbreak of coronary heart disease, take Western medicine blood pressure lowering and formed dependency.This medicine that takes the present invention is after March, and blood pressure is basicly stable within normal range, and blood fat obviously reduces, and coronary heart disease was not shown effect within 1 year.

Claims (1)

1. treat a medicine for diabetes, hypertension, hyperlipidemia and coronary heart disease, by the component of following weight parts, formed:

30 parts of Radix Rehmanniae, 10 parts of Radix Ophiopogonis, 20 parts of Radix Trichosanthis, 30 parts of Radix Puerariaes, 15 parts of Herba Epimedii, 30 parts of Radix Astragali, 20 parts of Rhizoma Dioscoreaes, 25 parts of Radix Achyranthis Bidentataes, 15 parts of Ramulus Uncariae Cum Uncis, 15 parts of Concha Meretricis seu Cyclinaes, 10 parts of Resina Ferulaes, 10 parts of Solenognathus, 25 parts of Radix Polygoni Multiflori, 10 parts of Herba Taxillis, 10 parts of Radix Curcumaes, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Pericarpium Trichosanthiss, 15 parts of Semen Cuscutae, 15 parts of Rhizoma Chuanxiongs.